Adsorption of Candida rugosa lipase at water-polymer interface: The case of poly(dl)lactide

► Thermodynamic study of Candida rugosa lipase interaction with PDLLA Langmuir monolayers. ► Mechanical properties study. ► Surface potential and dipole moment study. ► Candida rugosa lipase adsorption on PDLLA nanoparticles. ► Estimation of the heat of adsorption.