کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5524586 1401421 2017 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Thyroid functions and serum lipid profile in metabolic syndrome
ترجمه فارسی عنوان
عملکرد تیروئید و پروفایل لیپید سرم در سندرم متابولیک
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی تحقیقات سرطان
چکیده انگلیسی

BackgroundThyroid hormones are known to affect energy metabolism. Many patients of metabolic syndrome have subclinical or clinical hypothyroidism and vice versa. To study the correlation of thyroid profile and serum lipid profile with metabolic syndrome.MethodIt is a hospital based cross sectional case-control study carried out in tertiary care health center, we studied thyroid functions test and serum lipid profile in 100 metabolic syndrome patients according to IDF criteria and a similar number of age, gender and ethnicity matched healthy controls.ResultWe found that serum HDL was significantly lower (p < 0.001) in cases (41.28 ± 8.81) as compared to controls (54.00 ± 6.31). It was also found that serum LDL, VLDL, triglyceride levels and total cholesterol were found to be significantly higher (p < 0.001) in cases than controls. Serum TSH levels of subjects in cases group (3.33 ± 0.78) were significantly higher (p < 0.001) than that of controls (2.30 ± 0.91) and significantly lower levels of T4 (p < 0.001) in the patients of metabolic syndrome (117.45) than in controls (134.64) while higher levels of T3, although statistically insignificant in the patients of metabolic syndrome.ConclusionThyroid hormones up-regulate metabolic pathways relevant to resting energy expenditure, hence, obesity and thyroid functions are often correlated.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomedical Journal - Volume 40, Issue 3, June 2017, Pages 147-153
نویسندگان
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