Precore/core promoter mutations and hepatitis B virus genotype in hepatitis B and C dually infected patients treated with interferon-based therapy

► Prevalence and implications of HBV mutation/genotype in dual BC infection is unknown. ► Dual infection has a higher prevalence of genotype C and less G1896A mutation. ► Genotype C is associated with more A1762T/G1764A mutation, but less G1896A mutation. ► Specific HBV mutations could predict long-term HBV response after IFN therapy.