کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6052093 | 1583377 | 2009 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Epithelial histogenesis during tooth development
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کلمات کلیدی
FGFRPEKLEF-1MSXlymphoid enhancer binding factor 1bullous pemphigoid antigen 1EDARSEKBMPREFAFGFEDADiI - DIIEctodysplasin - اکاتوسیپلاسینIDE - اینجاTooth development - توسعه دندانStellate reticulum - ستون فقراتfibroblast growth factor - فاکتور رشد فیبروبلاستBMP - مدیریت فرایند کسب و کارBone morphogenetic protein - پروتئین مورفوژنیک استخوانfibroblast growth factor receptor - گیرنده فاکتور رشد فیبروبلاست
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
دندانپزشکی، جراحی دهان و پزشکی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
This paper reviews the current understanding of the progressive changes mediating dental epithelial histogenesis as a basis for future collaborative studies. Tooth development involves morphogenesis, epithelial histogenesis and cell differentiation. The consecutive morphological stages of lamina, bud, cap and bell are also characterized by changes in epithelial histogenesis. Differential cell proliferation rates, apoptosis, and alterations in adhesion and shape lead to the positioning of groups of cells with different functions. During tooth histo-morphogenesis changes occur in basement membrane composition, expression of signalling molecules and the localization of cell surface components. Cell positional identity may be related to cell history. Another important parameter is cell plasticity. Independently of signalling molecules, which play a major role in inducing or modulating specific steps, cell-cell and cell-matrix interactions regulate the plasticity/rigidity of particular domains of the enamel organ. This involves specifying in space the differential growth and influences the progressive tooth morphogenesis by shaping the epithelial-mesenchymal junction. Deposition of a mineralized matrix determines the final shape of the crown. All data reviewed in this paper were investigated in the mouse.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Archives of Oral Biology - Volume 54, Supplement 1, December 2009, Pages S25-S33
Journal: Archives of Oral Biology - Volume 54, Supplement 1, December 2009, Pages S25-S33
نویسندگان
H. Lesot, A.H. Brook,