Early Subclinical Macular Edema in Eyes with Uveal Melanoma: Association with Future Cystoid Macular Edema

Subclinical macular edema is common in eyes with uveal melanoma before and at 4 months after plaque radiotherapy and is associated with initial larger tumor size. Eyes with early subclinical macular edema are at significantly higher risk for future CME. These findings suggest that tumor-related factors, most likely mediated through proinflammatory cytokines, may play an important role in development of post-radiation CME.