کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7043412 1456911 2019 26 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Pre-purification by membrane filtration of paralytic shellfish toxins from Alexandrium minutum dinoflagellate
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی تصفیه و جداسازی
پیش نمایش صفحه اول مقاله
Pre-purification by membrane filtration of paralytic shellfish toxins from Alexandrium minutum dinoflagellate
چکیده انگلیسی
The Paralytic shellfish neurotoxins (PST) are of increasing interest for biomedical applications. The chemical synthesis is often complex and expensive that's why the purification by membrane filtration of PST from Alexandrium minutum dinoflagellate was investigated. Disrupted micro-alga cells by ultrasonic treatment were diafiltred to let pass toxins through an ultrafiltration membrane. Then, the mean permeate was concentrated and diafiltrated by nanofiltration. Mean permeate fluxes equal to 187, 135 and 135 L h−1 m−2 were obtained during the first diafiltration, the concentration step and the final diafiltration respectively. Up to 57% (mol/mol) and 78% (mol/mol) of organic matters and salts were removed respectively. Divalent ions were sparsely removed contrary to monovalent ones. C1 and C2 toxins were successfully purified since more than 75% (mol/mol) were recovered. However, only 27 to 50% (mol/mol) of GTX2, GTX3 and STX were recovered.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Separation and Purification Technology - Volume 210, 8 February 2019, Pages 152-158
نویسندگان
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