Sonographic assessment of the effect of praziquantel therapy on liver echotexture and diameters of the portal and splenic veins in patients with schistosomiasis

The liver echotexture and size were significantly recovered in patients who received PZQ therapy compared to those who did not use the drug (p-values < 0.001). PZQ caused significant reduction in diameters of the PV and SV (p-value <0.001). Conclusion: Liver size and echotexture and diameters of PV and SV improved well as a result of Praziquantel therapy in patients with chronic Schistosoma infection. Treatment of Schistosomiasis is necessary to prevent liver cirrhosis and portal hypertension.