Pharmacokinetic study of ginsenoside Rc and simultaneous determination of its metabolites in rats using RRLC-Q-TOF-MS

- RRLC-Q-TOF-MS method was developed for metabolic study of ginsenoside Rc in Rats.
- The mean plasma elimination half-lives of Rc in rats were determined.
- Rc and metabolites Mb, Mc and compound K were characterized in the metabolic study.
- The in vivo metabolic pathway of ginsenoside Rc were summarized.