Analysis of nanostructure of red blood cells membranes by space Fourier transform of AFM images

► This work extends the possibility to use atomic force microscopy for analyzing of membrane nanostructure of red blood cells. ► The space Fourier transform was used to decompose the complex AFM image of the surface into three simpler ones. ► The parameters of spectral windows selected according the natural structures of RBC membranes. ► This method allows to compare statistically the nanostructure alterations of cells membranes resulting blood intoxication in vitro.