کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8547067 | 1561727 | 2018 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Multiple mycotoxin exposure of infants and young children via breastfeeding and complementary/weaning foods consumption in Ecuadorian highlands
ترجمه فارسی عنوان
قرار گرفتن در معرض مایکوتوکسین چندگانه نوزادان و کودکان جوان از طریق تغذیه با شیر مادر و مصرف مکمل / شیرینی در سرزمینهای اکوادور
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کلمات کلیدی
PTDIBMDLDeoxynivalenolPMTDIOTAAFM1AFB1 - AFB 1Aflatoxin B1 - آفلاتوکسین B1Aflatoxin M1 - آفلاتوکسین M1Exposure assessment - ارزیابی قرار گرفتن در معرضOchratoxin A - اکراتوکسین AMOET - بایدMargin of exposure - حاشیه قرار گرفتن در معرضLOD یا Limit of detection - حد تشخیصprovisional maximum tolerable daily intake - حداکثر مصرف روزانه قابل تحمل روزانهDON - دونHazard quotient - سهم خطرHazard index - شاخص خطرBreast milk - شیر مادرMycotoxins - مایکوتوکسین ها limit of detection - محدودیت تشخیصprovisional tolerable daily intake - مصرف روزانه قابل تحمل روزانهMOE - وزارت صنایع
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
دانش تغذیه
چکیده انگلیسی
The dietary exposure to mycotoxins in Ecuadorian children aged 0-23 months (320 rural and 603 urban) was evaluated based on the intake of breast milk and staple cereals used as complementary/weaning foods. A probabilistic distribution approach by first order Monte Carlo simulation was adopted to assess the locally occurring mycotoxins (aflatoxins M1 and B1 in breast milk, ochratoxin A and deoxynivalenol in wheat noodles and oat flakes, and HT-2 toxin in polished rice). Overall, exposure was modest but higher for rural children due to their monotonous diet. Aflatoxin exposure by breast milk intake were of health concern in both areas (Margin of Exposure and Combined Margin of Exposure Index<10,000). Mycotoxin exposure by staple cereals intake was considered tolerable across feeding stages for individual mycotoxin-cereal combination (Hazard Quotient<1) and combined exposure (Hazard Index<1). The major exposure was to HT-2 toxin by rice intake at complementary feeding (15% rural and 4% urban above TDI) and at weaning stage (26% rural and 6% urban above TDI). Since the usual Ecuadorian diet is based on the same staple cereals, risk management actions could lead to a better protection of young children and also ensure higher safety of the recommended breastfeeding practices by protecting nursing mothers.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food and Chemical Toxicology - Volume 118, August 2018, Pages 541-548
Journal: Food and Chemical Toxicology - Volume 118, August 2018, Pages 541-548
نویسندگان
Johana Ortiz, Liesbeth Jacxsens, Gabriela Astudillo, Adriana Ballesteros, Silvana Donoso, Lieven Huybregts, Bruno De Meulenaer,