Susceptibility and severity of cancer-related fatigue in colorectal cancer patients is associated with SLC6A4 gene single nucleotide polymorphism rs25531 A>G genotype

The SERT gene promoter SNP rs25531 was associated with the CRF in patients with colon and rectal cancer and the G genotype was an independent risk factor for CRF among individuals with colon and rectal cancer in the study.