Clinical Utility of Left Atrial Strain in Children in the Acute Phase of Kawasaki Disease

In aKD, impaired left atrial reservoir function could be detected as decreased PALS. For differentiating aKD from controls, PALS outperforms E/E′, E/A, and LAVImax. However, like E/E′, E/A, and LAVImax, PALS as a single parameter is limited in its clinical utility to differentiate aKD from controls because of its low sensitivity and poor discriminative ability.