Response of single cell with acute angle exposed to an external electric field

• We optimized and formulated the response of a single cell under external EF.
• The response of model to EF depends on external EF and acute angle on the cell.
• The induced EF of cell model increases significantly with decreasing the angle.
• We calculated the value of power dissipation for this model.
• We calculated an electric field threshold that may damage the living cell.

It is known that the electric field incurs effects on the living cells. Predicting the response of single cell or multilayer cells to induced alternative or static eclectic field has permanently been a challenge. In the present study a first order single cell with acute angle under the influence of external electric field is considered. The cell division stage or the special condition of reshaping is modelled with a cone being connected. In the case of cell divisions, anaphase, it can be considered with two cones that connected nose-to-nose. Each cone consists of two regions. The first is the membrane modelled with a superficial layer, and the second is cytoplasm at the core. A Laplace equation is written for this model and the distribution of its electric field is a sharp point in the single cell for which an acute angle model is calculated.