کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9622608 | 160547 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Selection of twenty-four highly informative SNP markers for human identification and paternity analysis in Koreans
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آنالیزی یا شیمی تجزیه
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چکیده انگلیسی
A number of DNA marker types suitable for human identification and parentage testing have been developed, of which single nucleotide polymorphisms (SNPs) merit attention as they are abundant, genetically stable, and amenable to high-throughput automated analysis. In this regard, 24 highly informative SNP markers representing each 22 autosome and both sex chromosomes were selected, and the allele and genotype frequencies of these SNPs were determined in a group composed of 30 unrelated Koreans. Based on frequency data from this group, the estimated probability of identity (PI) and probability of paternity exclusion (PE) with 22 autosomal SNP loci were 1.905 Ã 10â10 and 98.9%, respectively. The SNPs in this study offer a small but highly accurate database that will be an essential reference for SNP-based forensic application in the future.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Forensic Science International - Volume 148, Issues 2â3, 10 March 2005, Pages 107-112
Journal: Forensic Science International - Volume 148, Issues 2â3, 10 March 2005, Pages 107-112
نویسندگان
Hwan Young Lee, Myung Jin Park, Ji-Eun Yoo, Ukhee Chung, Gil-Ro Han, Kyoung-Jin Shin,