Keywords: Toll like receptors; NOD like receptors; Lipopolysaccharide; CpG ODN; Unmethylated DNA;
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Keywords: CBA; Cytometric Bead Array; CPG ODN; CpG oligodeoxynucleotide; DC; dendritic cells; LPS; lipopolysaccharide; PBMC; peripheral blood mononuclear cell; PGN; peptidoglican; Poly I:C; Polyinosinic-polycytidylic acid; PRR; pattern-recognition receptor; TLR; To
Keywords: SIRS; systemic inflammatory response syndrome; D-GalN; D-galactosamine; CpG ODN; oligodexynucleotides containing CpG motifs; CCT ODN; oligodexynucleotides containing CCT motifs; mtDNA; mitochondrial DNA; PLCs; peritoneal lavage cells; sTLR9; surface Toll-
Keywords: Pattern recognition receptors; Innate immunity; DAMP; Endoplasmic reticulum stress; Excitotoxicity; Cytokine; Chemokine; CpG ODN; Neuroprotection; Neurodegeneration; Injury;
Keywords: BMDM; bone marrow-derived macrophages; CpG ODN; oligodeoxynucleotides containing unmethylated cytosine-phosphate-guanine; DMEM; Dulbecco's Modified Eagle Medium; RPMI; Roswell Park Memorial Institute; FACS; fluorescence-activated cell sorter; MFI; mean fl
Oral administration of PLGA-encapsulated CpG ODN and Campylobacter jejuni lysate reduces cecal colonization by Campylobacter jejuni in chickens
Keywords: Chicken; Campylobacter; Toll-like receptor ligand; CpG ODN; Nanoparticle; PLGA;
Synergistic effect of co-stimulation of membrane and endosomal TLRs on chicken innate immune responses
Keywords: TLR; toll like receptor; TLR-Ls; toll-like receptor ligands; BMMs; bone marrow-derived macrophages; PCSK; pam3Cys-SK4; MPLA; synthetic monophosphoryl lipid A; KLA; Di[3-deoxy-d-manno-octulosonyl]-lipid A ammonium salt; R848; resiquimod; CpG; cytosine-phos
Oral immunization with Porphyromonas gingivalis outer membrane protein and CpG oligodeoxynucleotides attenuates P. gingivalis-accelerated atherosclerosis and inflammation
Keywords: 40k-OMP; 40-kDa outer membrane protein of Porphyromonas gingivalis; CpG ODN; synthetic oligodeoxynucleotides containing unmethylated CpG dinucleotides; CT; cholera toxin; Oral vaccine; Porphyromonas gingivalis; Chronic periodontitis; Atheromatous lesions;
Gene expression profiling of chicken cecal tonsils and ileum following oral exposure to soluble and PLGA-encapsulated CpG ODN, and lysate of Campylobacter jejuni
Keywords: Chicken; Cecal tonsils; Ileum; Campylobacter; CpG ODN; Nanoparticle; PLGA; Cytokines; Antimicrobial peptides;
CpG oligodeoxynucleotides with crude parasite antigens reduce worm recovery in Opisthorchis viverrini infected hamsters
Keywords: CpG ODN; Opisthorchis viverrini; Protection; Hamster; T cells; IFN-γ;
Delivery of an inactivated avian influenza virus vaccine adjuvanted with poly(D,L-lactic-co-glycolic acid) encapsulated CpG ODN induces protective immune responses in chickens
Keywords: Avian influenza virus; Chickens; CpG ODN; Poly(D,L-lactic-co-glycolic acid); Delivery system; Nanoparticle; Immune response;
Epithelial-mesenchymal transition promotes reactivity of human lung adenocarcinoma A549 cells to CpG ODN
Keywords: A549 cells; Asthma; CpG ODN; Epithelial-mesenchymal transition; RemodelingEMT, epithelial-mesenchymal transition; ODN, oligodeoxynucleotides; TLR, Toll-like receptor
CpG ODN mimicking CpG rich region of myxosporean Myxobolus supamattayai stimulates innate immunity in Asian sea bass (Lates calcarifer) and defense against Streptococcus iniae
Keywords: CpG ODN; Lates calcarifer; Immunostimulant; Innate immunity; Streptococcus iniae;
Evidence for the existence of regulatory and effector B cell populations in Peyer's patches of sheep
Keywords: Immune regulation; Regulatory cells; Bregs; Effector B cells; Peyer's patches; TLR9; CpG ODN;
Induction of a balanced Th1/Th2 immune responses by co-delivery of PLGA/ovalbumin nanospheres and CpG ODNs/PEI-SWCNT nanoparticles as TLR9 agonist in BALB/c mice
Keywords: Single-walled carbon nanotubes; Polyethylenimine; CpG ODN; Adjuvant delivery; PLGA; Ovalbumin;
Systemic immune responses to an inactivated, whole H9N2 avian influenza virus vaccine using class B CpG oligonucleotides in chickens
Keywords: Toll-like receptor 21; Low pathogenic avian influenzavirus; H9N2 subtype; CpG oligodeoxynucleotides; Chickens; Antibody response; Haemagglutination inhibition; Virus neutralization; ELISA; TLR; Toll-like receptor; ODN; oligodeoxynucleotide; CpG ODN; ODN c
Potentiation of antigen-specific antibody production by peptides derived from Ag85B of Mycobacterium tuberculosis
Keywords: FCA; Freund's complete adjuvant; CpG ODN; CpG oligodeoxynucleotide; MDP; Muramyl dipeptide; OVA; Ovalbumin; PBS; Phosphate-buffered saline; FBS; Fetal bovine serum; AP; Altered peptide; Antibody; Immunization; Adjuvant; Peptide-25; MHC-II; Th2;
Phase 1 testing of detoxified LPS/group B meningococcal outer membrane protein vaccine with and without synthetic CPG 7909 adjuvant for the prevention and treatment of sepsis
Keywords: TSH; thyroid stimulating hormone; ECL; electrochemiluminescence; GNB; Gram-negative bacteria; MDR; multidrug resistant; gMFI; geometric mean fold increase; OMP; outer membrane protein; dLPS; detoxified LPS; CpG; cytosine and guanosine triphosphate oligode
Immune modulation of T regulatory cells and IgE responses in horses vaccinated with West Nile virus vaccine combined with a CpG ODN
Keywords: Equine; IgE; Vaccines; CpG ODN; Adverse vaccine responses;
Class B CpG ODN stimulation upregulates expression of TLR21 and IFN-γ in chicken Harderian gland cells
Keywords: Harderian gland; CpG ODN; Chicken; TLR; Interleukins
C7: A CpG oligodeoxynucleotide that induces protective immune response against megalocytivirus in Japanese flounder (Paralichthys olivaceus) via toll-like receptor 9-mediated signaling pathway
Keywords: CpG ODN; Paralichthys olivaceus; Megalocytivirus; Immunostimulant; Adjuvant
CpG oligodeoxynucleotide protect neonatal piglets from challenge with the enterotoxigenic E. coli
Keywords: The piglets; CpG ODN; Enterotoxigenic Escherichia coli; Innate immunity;
CpG oligodeoxynucleotides with double stem-loops show strong immunostimulatory activity
Keywords: CpG ODN; TLR9; Tumor immunology
Hemocytic immune responses triggered by CpG ODNs in shrimp Litopenaeus vannamei
Keywords: CpG ODN; Litopenaeus vannamei; Apoptosis; Hematopoiesis; Phagocytosis
Novel Bregs down-regulate TLR9-induced cytokine responses in sheep Peyer's patches
Keywords: Immune regulation; Regulatory cells; Bregs; Peyer's patches; Toll-like receptors; TLR9; CpG ODN; Sheep;
TLR9 agonists: Immune mechanisms and therapeutic potential in domestic animals
Keywords: TLR9; CpG ODN; Immune mechanisms; Immunotherapy; Adjuvants; Vaccines; Animals;
A CpG oligodeoxynucleotide potentiates the anti-tumor effect of HSP65-Her2 fusion protein against Her2 positive B16 melanoma in mice
Keywords: CpG ODN; Adjuvant; HSP65; Tumor vaccine; Anti-tumor effect;
The role of liposome-protamine-DNA nanoparticles containing CpG oligodeoxynucleotides in the course of infection induced by Leishmania major in BALB/c mice
Keywords: LPD nanoparticles; CpG ODN; Leishmania major; Leishmanization; Immune response;
Leishmania donovani recombinant iron superoxide dismutase B1 protein in the presence of TLR-based adjuvants induces partial protection of BALB/c mice against Leishmania major infection
Keywords: Leishmania; Superoxide dismutase; Vaccine; CpG ODN; GLA;
Prophylactic treatment with Toll-like receptor ligands enhances host immunity to avian influenza virus in chickens
Keywords: Chicken; Avian influenza virus; Toll-like receptors; Poly I:C; CpG ODN; LPS; Immune response; Cytokines;
Targeted delivery of CpG ODN to CD32 on human and monkey plasmacytoid dendritic cells augments IFNα secretion
Keywords: DC, dendritic cell; IFN, interferon; mDC, myeloid DC; pDC, plasmacytoid DC; TLR, Toll Like ReceptorAllergy; CD32a; CpG ODN; Plasmacytoid dendritic cell; Targeting
Discrepant roles of CpG ODN on acute alcohol-induced liver injury in mice
Keywords: CpG ODN; TLR9; Alcohol; Liver injury; TNF-α; IFN-α
Effects of orally administered immunostimulants on inflammatory gene expression and sea lice (Lepeophtheirus salmonis) burdens on Atlantic salmon (Salmo salar)
Keywords: Atlantic salmon; Sea lice; Lepeophtheirus salmonis; CpG ODN; β-Glucans; Inflammatory response
Innate defense regulator peptide synergizes with CpG ODN for enhanced innate intestinal immune responses in neonate piglets
Keywords: CpG ODN; Innate defense-regulator peptides; Innate intestinal immune responses; Neonatal piglets;
CpG oligodeoxynucleotide and montanide ISA 206 adjuvant combination augments the immune responses of a recombinant FMDV vaccine in cattle
Keywords: CpG ODN; FMDV; Vaccine; Cattle;
CpG oligodeoxynucleotide-adjuvanted fusion peptide derived from HBcAg epitope and HIV-Tat may elicit favorable immune response in PBMCs from patients with chronic HBV infection in the immunotolerant phase
Keywords: Chronic hepatitis B; IFN-γ; Cytotoxic T lymphocyte response; HBcAg18–27; HIV-Tat49–57; CpG ODN
CpG oligodeoxynucleotide synergizes innate defense regulator peptide for enhancing the systemic and mucosal immune responses to pseudorabies attenuated virus vaccine in piglets in vivo
Keywords: The newborn piglets; Pseudorabies attenuated virus vaccine; CpG ODN; Innate defense-regulator peptides; Immune response
Cell activation by CpG ODN leads to improved electrofusion in hybridoma production
Keywords: CpG ODN; CpG oligodeoxynucleotide; PEG; Polyethyleneglycol; HAT; Hypoxanthine; LPS; Lipopolysaccharide; PWM; Pokeweed mitogen; IL-2; Interleukin-2; PBS; Phosphate buffered saline; FBS; Fetal bovine serum; IL-10; Interleukin-10; IL-12; Interleukin-12; GM-C
Enhanced humoral and mucosal immune responses after intranasal immunization with chimeric multiple antigen peptide of LcrV antigen epitopes of Yersinia pestis coupled to palmitate in mice
Keywords: MAP construct; Adjuvant; CpG ODN; Mucosal immunity; Yersinia; V antigen;
Cytokine content in lymphoid and white adipose tissues after repeated CpG oligodeoxynucleotide administration in trained rats
Keywords: CpG ODN; Physical training; Cytokine
CpG oligonucleotides induce an immune response of odontoblasts through the TLR9, MyD88 and NF-κB pathways
Keywords: Odontoblast; CpG ODN; TLR9; MyD88; NF-κB;
Identification and analysis of the immune effects of CpG motifs that protect Japanese flounder (Paralichthys olivaceus) against bacterial infection
Keywords: CpG ODN; Paralichthys olivaceus; Immunostimulant; DNA vaccine
A novel canine favored CpG oligodeoxynucleotide capable of enhancing the efficacy of an inactivated aluminum-adjuvanted rabies vaccine of dog use
Keywords: CpG ODN; Rabies vaccine; Dog
Subcutaneous, but not intratracheal administration of the TLR9 agonist, CpG DNA transiently reduces parainfluenza-3 virus shedding in newborn lambs
Keywords: CpG ODN; Toll-like receptors; Innate immunity; Neonates; Sheep; Parainfluenza-3 virus
CpG ODN pretreatment attenuates concanavalin A-induced hepatitis in mice
Keywords: ODN, synthetic oligodeoxynucleotide; CpG ODN, ODN containing CpG motifs; MNC, mononuclear cell; IFN-γ, interferon gamma; TNF-α, tumor necrosis factor alphaConcanavalin A; CpG ODN; TNF-α; IFN-γ; NF-κB
HBcAg18–27 epitope fused to HIV-Tat49–57 adjuvanted with CpG ODN induces immunotherapeutic effects in transgenic mice
Keywords: Chronic hepatitis B; HBcAg18–27; HIV-Tat49–57; CpG ODN; Immune response; Transgenic mice
Anti-tumor immune response correlates with neurological symptoms in a dog with spontaneous astrocytoma treated by gene and vaccine therapy
Keywords: Canine glioma; CpG ODN; Gemistoctyic astrocytoma; Interferon gamma; Adenovirus
Plasmid containing CpG oligodeoxynucleotides can augment the immune responses of pigs immunized with porcine reproductive and respiratory syndrome killed virus vaccine
Keywords: Pig; Porcine reproductive and respiratory syndrome killed virus vaccine; CpG ODN; Immune response; Antibody dependent enhancement effect
Administered CpG oligodeoxynucleotide induces mRNA expression of CXC and CC chemokines at the intestinal mucosa and PBMCs in piglets
Keywords: Piglets; CpG ODN; Chemokines; Innate immunity
Identification and analysis of a CpG motif that protects turbot (Scophthalmus maximus) against bacterial challenge and enhances vaccine-induced specific immunity
Keywords: CpG ODN; Adjuvant; Scophthalmus maximus; Immunostimulant