Keywords: SERT; serotonin transporter; NET; norepinephrine transporter; DAT; dopamine transporter; NSS; neurotransmitter/sodium (Na+/Clâ) symporter; SSRI; selective serotonin reuptake inhibitor; NBD; nitrobenzoxadiazolealanine; NMM; N-methylmorpholine; NHS; N-hyd
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Keywords: scFv; single chain antibody fragment; PBS/NCS; phosphate-buffered saline/neonatal calf serum; POD; horseradish peroxidase; TMB; tetramethylbenzidine; FITC; fluorescein isothiocyanate; NHS; N-hydroxysuccinimide; IPTG; isopropyl-β-d-thiogalactopyranoside;
Keywords: EDC; 1-ethyl-3-(3-dimethylpropyl)-carboiimide; DU; D-antigen unit; ELISA; enzyme-linked immunosorbent assay; EWS; European Working Standard; HBS-EP; hepes-buffered saline containing EDTA and the P20 detergent; Ig; immunoglobulin; IPV; inactivated polio va
Keywords: αCD44; anti-CD44 antibody; bTyr-NSP; biotinylated tyrosine-derived nanospheres; bTyr-NSP-PTX; biotinylated tyrosine-derived nanospheres loaded with paclitaxel; CTAB; cetyltrimethylammonium bromide; ESA; epithelial-specific antigen; DCC; N,Nâ²-dicyclohex
Keywords: N-hydroxysuccinimide; Graphene nanosheets; Cadmium telluride; Quantum dot; Photoelectrocatalytic oxidation; Aliphatic alcohols;
Keywords: Minoxidil; Polyamines; Conjugates; Antioxidant activities; Anti-inflammatory activities; Lipoxygenase inhibitors; Lipid peroxidation; Cytotoxicity; AAPH; 2,2-azo-bis(2-amidinopropane) dihydrochloride; ABTS; 2,2â²-azinobis(3-ethylbenzothiazoline-6-sulfoni
Keywords: (EPR); Electron paramagnetic resonance; (LMSs); Laccase mediator systems; (ITO); Indium tin oxide; (GLU); Glutaraldehyde; (NHS); N-hydroxysuccinimide; (NPG); Nanoporous gold; (EDC); 1-Ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride; (PHEMAH); P
Glutathione responsive chitosan-thiolated dextran conjugated miR-145 nanoparticles targeted with AS1411 aptamer for cancer treatment
Keywords: miRNAs; micro RNAs; PU-PEI; polyurethane-short branch-polyethylenimine; PEI; polyethylenimine; siRNA; small interfering RNA; TD; thiolated dextran; L-Cys; L-cysteine; CMD; carboxymethyl dextran; GSH; glutathione; PEC; polyelectrolyte complexes; Mw; molecu
Fragment screening for drug leads by weak affinity chromatography (WAC-MS)
Keywords: 3-ABA; 3-aminobenzamidine; 4-ABA; 4-aminobenzamidine; AmAc; ammonium acetate; APCI; atmospheric pressure chemical ionization; AQP1; human aquaporin-1; BA; benzamidine; BCA; bicinchoninic acid; CMC; critical micelle concentration; DMSO; dimethyl sulfoxide;
BPN, a marine-derived PTP1B inhibitor, activates insulin signaling and improves insulin resistance in C2C12 myotubes
Keywords: T2DM; type 2 diabetes mellitus; PTP1B; protein tyrosine phosphatase 1B; BPN; 3,4-dibromo-5-(2-bromo-3, 4-dihydroxy-6-(ethoxymethyl)benzyl) benzene-1,2-diol; GLUT4; glucose transporter 4 translocation; INS; insulin; IR; insulin receptor; IRS-1; IR substrat
Recent advances of immunosensors for detecting food allergens
Keywords: (F(ab')2-HRP); Peroxidase-conjugated AffiniPure F(ab')2 Fragment Goat anti-Rabbit IgG; 3-IP; 3-indoxyl phosphate; 5-HTA; 5 - hydroxy tryptamine; AbD; Detector antibody; Ag+; Silver ions; AntiHA-Ab; Anti-histamine antibody; AuNPs; Gold nanoparticles; b
Recent progress in nanostructured magnetic framework composites (MFCs): Synthesis and applications
Keywords: Magnetic nanoparticles; Metal organic frameworks; Synthesis; Application; Hybrid material; AEAPTMS; N-(3-(Trimethoxysilyl)propyl) ethylenediamine; AOP; Advanced Oxidation Processes; APTES; (3-Aminopropyl)triethoxysilane; H2BDC; Benzenedicarboxylic Acid; B
Preparation, evaluation and optimization of nanoparticles composed of thiolated triethyl chitosan: A potential approach for buccal delivery of insulin
Keywords: Insulin nanoparticles; Thiolated chitosan; Box-Behnken response surface methodology; Buccal drug delivery; Cys; L-cysteine; TEC; triethyl chitosan; TEC-Cys; thiolated N-triethyl chitosan; NMP; N-methyl pyrrolidone; NHS; N-hydroxysuccinimide; DTNB; 5, 5â²
Expression of active chimeric-tissue plasminogen activator in tobacco hairy roots, identification of a DNA aptamer and purification by aptamer functionalized-MWCNTs chromatography
Keywords: Aptamer; Chimeric-tissue plasminogen activator; Cloning; Cuscutain; Hairy root; SELEX; SOEing-PCR; Splicing Overlap Extension Polymerase Chain Reaction; SELEX; systematic evolution of ligands; tPA; Tissue-type plasminogen activator; CNTs; Carbon nano tube
Minimum structural requirements for BMP-2-binding of heparin oligosaccharides
Keywords: Heparin; Glycosaminoglycan; BMP-2; Bone repair; BMP; bone morphogenetic protein; GAGs; glycosaminoglycans; HS; heparan sulfate; CS; chondroitin sulfate; DS; dermatan sulfate; KS; keratan sulfate; ALP; alkaline phosphatase; dp; degree of polymerization; DS
Multimodal imaging for a theranostic approach in a murine model of B-cell lymphoma with engineered nanoparticles
Keywords: Mouse model; Preclinical imaging; Theranostic; Fluorescence imaging; Magnetic resonance; Engineered nanoparticles; HA; Hyaluronic acid; NPs; nanoparticles; Ig-BCR; immunoglobulin B-cell receptor; pA20-36; peptide A20-36; pCNT; scrambled or control peptide
Modulation of in vitro phagocytic uptake and immunogenicity potential of modified Herceptin®-conjugated PLGA-PEG nanoparticles for drug delivery
Keywords: NPs; nanoparticles; TNF-α; tumor necrosis factor alpha; PEG; polyethylene glycol; PLGA; poly (D L- lactide-co-glycolide); MALDI; matrix assisted laser desorption/ionization; TOF; time-of-flight; TFA; trifluoroacetic acid; DCM; dichloromethane; EDC; 1-eth
Growth of Escherichia coli on the GaAs (001) surface
Keywords: CFU; Colony forming unit; PCR; Polymerase chain reaction; SPR; Surface plasmon resonance; PL; Photoluminescence; SI; Semi-insulating; DI water; Deionized water; AS; Ammonium sulfide; b-PEG; Biotinylated polyethylene glycol; LB; Luria Bertani; PBS; Phospha
PDMS with designer functionalities-Properties, modifications strategies, and applications
Keywords: AgNW; silver nanowires; APTES; 3-aminopropyl)triethoxysilane; ATRP; atom transfer radical polymerisation; BSA; bovine serum albumin; CNT; carbon nanotubes; CuNW; copper nanowires; CVD; chemical vapour deposition; FITC; fluorescein isothiocyanate; GO; grap
Molecular mechanism of Arabidopsis thaliana profilins as antifungal proteins
Keywords: Profilin; Antifungal protein; Arabidopsis; Apoptosis; ROS; AtPFN; Arabidopsis thaliana profilin; CD; circular dichroism; CLSM; confocal laser scanning microscopy; DAPI; 4â²,6-diamidino-2-phenylindole; EDTA; ethylenediaminetetraacetic acid; FPLC; fast pro
The gene product of a Trypanosoma equiperdum ortholog of the cAMP-dependent protein kinase regulatory subunit is a monomeric protein that is not capable of binding cyclic nucleotides
Keywords: Trypanosoma equiperdum; Regulatory subunits of the cAMP-dependent protein kinase; Gene cloning; Protein expression in bacteria; Protein purification; Biochemical characterization; Dourine; Trypanosomatid parasites; PKA; cAMP-dependent protein kinase; R; P
Synthesis of hybrid materials using graft copolymerization on non-cellulosic polysaccharides via homogenous ATRP
Keywords: AAP; 4-aminoantipyrine; AGET; activators generated by electron transfer; AGP; agarose palmitate; AGU; anhydroglucose unit; AMIMB; 1-allyl-3-methylimidazolium bromide; AS; acetylated starch; Au NPs; gold nanoparticles; BIBA; α-bromoisobutyric acid; BIBB;
Natural polyphenols as versatile platforms for material engineering and surface functionalization
Keywords: ABTS+; 2,2â²-azino-bis(3-ethylbenzthiazoline-6-sulfonic acid); AgNPs; silver nanoparticles; AgrTA; tannic acid-functionalized agarose; ALP; alkaline phosphatase; A. niger; Aspergillus niger; APTES; 3-aminopropyltriethoxysilane; AuNPs; gold nanoparticles;
Smart polymersomes and hydrogels from polypeptide-based polymer systems through α-amino acid N-carboxyanhydride ring-opening polymerization. From chemistry to biomedical applications
Keywords: ADSCs; adipose derived stem cells; AFM; atomic force microscopy; AG; l/dl-allylglycine; AIBN; 2,2â²-azobisisobutyronitrile; Ala; alanine; ATR-FTIR; attenuated total reflectance Fourier transform infrared spectroscopy; ATRP; atom transfer radical polymeri
Preparation of UV-curable alginate derivatives for drug immobilization on dressing foam
Keywords: Az-alginate; Azidophenyl alginate; EDC; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; NHS; N-hydroxysuccinimide; MES; 2-(N-morpholino)ethanesulfonic acid; UV; Ultraviolet Ray; BSA; Bovine serum albumin; FITC-BSA; Fluorescein isothiocyanate-conjugated bov
Calcium phosphate-polymer hybrid nanoparticles for enhanced triple negative breast cancer treatment via co-delivery of paclitaxel and miR-221/222 inhibitors
Keywords: miR; micro RNA; miRi; micro RNA inhibitor; pac; paclitaxel; ER; estrogen receptor; PR; progesterone receptor; HER2/neu; epidermal growth factor receptor 2; TNBC; triple-negative breast cancer; PLGA; poly(d,l-lactide-co-glycolide); PEG; poly(ethylene-glyco
Major findings and recent advances in virus-like particle (VLP)-based vaccines
Keywords: VLP; virus-like particle; CCMV; cowpea chlorotic mottle virus; HBV; hepatitis B virus; PASP; pathogen associated structural pattern; BCR; B cell receptor; APC; antigen presenting cell; LN; lymph node; SCS; sub capsular sinus; DC; dendritic cell; cDC; conv
Development of long-acting ciliary neurotrophic factor by site-specific conjugation with different-sized polyethylene glycols and transferrin
Keywords: CNTF; ciliary neurotrophic factor; PEG; poly(ethylene glycol); Tf; transferrin; PEG-MAL; methoxy-PEG-maleimide; DIO; diet induced obesity; NHS; N-hydroxysuccinimide; ESI-MS; electrospray ionization mass spectrometry; PEGylation; Transferrin coupling; Lo
Thermodynamics of interactions between mammalian cytochromes P450 and b5
Keywords: Cytochrome P450; Cytochrome b5; SPR; Optical biosensor; Thermodynamics; Protein-protein interactions; CYP; â¿ytochrome P450; CYB5; â¿ytochrome b5; CYB5A and CYB5B; microsomal and mitochondrial isoforms of b5; SPR; surface plasmon resonance; RU; resonanc
PLGA-PEG-PLGA triblock copolymeric micelles as oral drug delivery system: In vitro drug release and in vivo pharmacokinetics assessment
Keywords: UA; Ursolic acid; US597; a derivatives of UA; US597@micelles; the formulation of PLGA-PEG-PLGA tri-block micelles loaded with US597; PAMAM; polyamidoamine; SD rats; Sprague-Dawley rats; UPLC/MS/MS; Ultra-performance liquid chromatography tandem mass-spe
Trimethyl chitosan based conjugates for oral and intravenous delivery of paclitaxel
Keywords: 2â²SPTX; 2â²-O-succinyl-paclitaxel; AUC; area under the concentrationtime curve; BSA; bovine serum albumin; CMC; critical micelle concentration; DMEM; Dulbecco's Modified Eagle Medium; DMSO; dimethyl sulfoxide; DSC; differential scanning calorimetry;
Intensity fading MALDI-TOF mass spectrometry and functional proteomics assignments to identify protease inhibitors in marine invertebrates
Keywords: MALDI.MS; as matrix-assisted laser desorption ionization mass spectrometry, in the TOF or TOF/TOF mode; IF-MALDI.MS or IF-MS or IF MALDI-TOF or TOF/TOF MS; as intensity fading MALDI-TOF mass spectrometry; MALDI-TDS; MALDI-top-down sequencing; CID; collisi
Application of nanocrystalline CdTe quantum dots in chemical analysis: Implementation of chemo-sensing schemes based on analyte-triggered photoluminescence modulation
Keywords: EDC; 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide; EMIDCA; 1-ethyl-3-methylimidazolium dicyanamide; Phen; 1,10-phenanthroline; BQ; 1,4-benzoquinone; MEA; 2-mercaptoethylamine; MPA; 3-mercaptopropionic acid; 4AT; 4-amino-2,2,6,6-tetramethylpiperidine-N-ox
Quantification of Rac1 and Rac1b in serum of non small cell lung cancer by label free real time assay
Keywords: NSCLC; Non Small Cell Lung Cancer; pre chemo; pre chemotherapy; Post chemo; post chemotherapy; SPR; surface plasmon resonance; EDC; N-ethyl-Nâ²-3diethylaminopropyl carbodiimide; NHS; N-hydroxysuccinimide; RU; response units; PVDF; polyvinylidene difluori
Characterizing nerve growth factor-p75NTR interactions and small molecule inhibition using surface plasmon resonance spectroscopy
Keywords: Nerve growth factor; Surface plasmon resonance; NGF inhibition; p75NTR; TrkA; Biosensor; NGF; nerve growth factor; SPR; surface plasmon resonance; HBS-EP; Hepes-buffered saline with EDTA and surfactant P20; EDTA; ethylenediaminetetraacetic acid; EDC; 1-
First paraben substituted cyclotetraphosphazene compounds and DNA interaction analysis with a new automated biosensor
Keywords: m.p.; melting point; THF; tetrahydrofuran; TLC; thin layer chromatography; DMSO; dimethylsulfoxide; TMS; tetramethylsilane; HRP; horseradish peroxidase; TMB; 3,3â²,5,5â²-Tetramethylbenzidine; Tris-HCI; ethylenediaminetetraacetic acid; NHS; N-hydroxysu
l-tryptophan and dipeptide derivatives for supercoiled plasmid DNA purification
Keywords: NMR; nuclear magnetic resonance; STD; Saturation Transfer Difference; HR-MAS; high resolution magic angle spinning; SPR; surface plasmon resonance; 5´-GMP; guanosine 5â²-monophosphate; 3´-AMP; adenosine 5â²-monophosphate; 5´-TMP; thymidine 5â²-monop
Poly(α-hydroxy acid)s and poly(α-hydroxy acid-co-α-amino acid)s derived from amino acid
Keywords: COCl2; phosgene; EDC; N-(3-dimethylaminopropyl)-Nâ²-ethylcarbodiimide hydrochloride; NHS; N-hydroxysuccinimide; DCC; N,Nâ²-dicyclohexylcarbodiimide; HOBt; hydroxybenzotriazole; PTSA; 4-toluenesulfonic acid/p-toluenesulfonic acid; PEA; poly(esteramide);
PLGA-based nanoparticles: A new paradigm in biomedical applications
Keywords: Biodegradable; Poly(lactic-co-glycolic acid); Nanoparticles; Targeting; Sustained release; DCC; N,N-Dicyclohexylcarbodiimide; DDS; Drug delivery system; DNA; Deoxyribose nucleic acid; EDC; 1-ethyl-3-(3-dimethylaminopropyl carbodiimide); EGFR; Epidermal gr
Direct determination of the redox status of cysteine residues in proteins in vivo
Keywords: NHS; N-hydroxysuccinimide; AMS; 4-acetamido-4â²-maleimidylstilbene-2,2â²-disulfonic acid; PEG-Mal; methoxypolyethylene glycol-maleimide; PEO; biotin-PEG11-maleimide; ssDNA; single-stranded DNA; Trxβ; fusion protein of the cytosolic thioredoxin h1 from
C60 carboxyfullerene-based functionalised nanohybrids as signal-amplifying tags for the ultrasensitive electrochemical detection of procalcitonin
Keywords: anti-PCT I; primary antibody; anti-PCT II; secondary antibody; AuNPs; gold nanoparticles; BSA; bovine serum albumin; CBC; l-cysteine-branched chitosan; Cdl; double-layer capacitance; CLEIA; chemiluminescence enzyme immunoassay; CV; cyclic voltammetry; DPV
The furofuran-ring selectivity, hydrogen peroxide-production and low Km value are the three elements for highly effective detoxification of aflatoxin oxidase
Keywords: AFB1; aflatoxin B1; AFO; aflatoxin oxidase; BF; benzofuran; CV; cyclic voltammetry; DHP; 3,4-dihydro-2H-pyran; DPV; differential pulse voltammetry; EDC; 1-ethyl-3-(3-dimethylaminepropyl) carbodiimide; FR; furan; HRP; horseradish peroxidase; ITC; isotherma
Synthesis and structure formation in dilute aqueous solution of a chitosan-DNA hybrid
Keywords: Chitosan; DNA; Self-assembly; Chitosan-grafted-single stranded DNA; Chitosan-g-ssDNA; degree of acetylation; DA; controlled pore glass; CpG; gel permeation chromatography; GPC; 2-(N-morpholino)ethanesulfonic acid buffer; MES; N-hydroxysuccinimide; NHS; 1-
High affinity anti-Internalin B VHH antibody fragments isolated from naturally and artificially immunized repertoires
Keywords: ELISA; enzyme-linked immunosorbent assay; IMAC; immobilized metal ion affinity chromatography; InlA; Internalin A; InlB; Internalin B; IPTG; isopropyl β-D-1-thiogalactopyranoside; LAC; llama-alpaca-camel; LRR; leucine-rich repeat; MWCO; molecular weight
A novel synthetic luteinizing hormone-releasing hormone (LHRH) analogue coupled with modified β-cyclodextrin: Insight into its intramolecular interactions
Keywords: BOP; benzotriazole-1-yl-oxy-tris-(dimethylamino)-phosphonium hexafluorophosphate; CLTR-Cl; 2-chlorotrityl chloride; DCC; N,Nâ²-dicyclohexylcarbodiimide; DMA; dimethylacetamide; DIC; N,Nâ²-diisopropylcarbodiimide; DIEA; diisopropylethylamine; DMF; N,N-di
A dual inhibitor of matrix metalloproteinases and a disintegrin and metalloproteinases, [18F]FB-ML5, as a molecular probe for non-invasive MMP/ADAM-targeted imaging
Keywords: ACN; acetonitrile; AcOH; acetic acid; ADAM; a disintegrin and metalloproteinase; CD; catalytic domain; DCC; N,Nâ²-dicyclohexylcarbodiimide; DCM; dichloromethane; DMF; N,N-dimethylformamide; ECM; extracellular matrix; EOB; end of bombardment; EOS; end of
Oral delivery of shRNA based on amino acid modified chitosan for improved antitumor efficacy
Keywords: Chitosan; Amino acid modification; Survivin shRNA; Oral delivery; Antitumor efficacy; ANOVA; analysis of variance; CH; chitosan-histidine; CHC30; chitosan-histidine-cysteine with molecular weight of 30Â kDa; CHC30 NC; CHC30/ shSur-pDNA nanocomplexes
Targeting docetaxel-PLA nanoparticles simultaneously inhibit tumor growth and liver metastases of small cell lung cancer
Keywords: SCLC; small cell lung cancer; DTX; docetaxel; PLA; polylactic acid; DN; docetaxel nanoparticles; AP-DN; AP conjugated docetaxel nanoparticles; EDC; 1-ethyl-3-(3-dimethylamino-propyl) carbodiimide; PVA; polyvinyl alcohol; NHS; N-hydroxysuccinimide; FBS; fe
Cyclic-RGDfK peptide conjugated succinoyl-TPGS nanomicelles for targeted delivery of docetaxel to integrin receptor over-expressing angiogenic tumours
Keywords: 1H NMR; Proton nuclear magnetic resonance; AO; Acridine orange; CMC; Critical micellar concentration; cRGDfK; Cyclo(-Arg-Gly-Asp-D-Phe-Lys); DMEM; Dulbecco's modified eagle medium; DMSO; Dimethyl sulfoxide; DNM; Docetaxel loaded TPSA nanomicelles; DPBS;
Functionalized polythiophenes: Recognition materials for chemosensors and biosensors of superior sensitivity, selectivity, and detectability
Keywords: A; adenine; ATP; adenosine-5â²-triphosphate; AuNP; gold nanoparticle; C; cytosine; CRP; C-reactive protein; CV; cyclic voltammetry; DMMP; dimethyl methylphosphonate; DNA; deoxyribonucleic acid; DPASV; differential pulse anodic stripping voltammetry; dsDN