دانلود مقالات ISI درباره Srebp-2 + ترجمه فارسی

تنظیم پروتئین کلسترول و اسیدفولیک اسید در بیماری های کبدی چربی و آترواسکلروز

Cholesterol and bile acid-mediated regulation of autophagy in fatty liver diseases and atherosclerosis

Keywords: NAFLD; nonalcoholic fatty liver disease; NASH; nonalcoholic steatohepatitis; FC; free cholesterol; VLDL; very low density lipoprotein; LDL; low density lipoprotein; mTOR; mechanistic target of rapamycin signaling; AMPK; AMP-activated protein kinase; TG; t

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

مکانیسم پلاسمایی در معرض قرار گرفتن در معرض نیکوتین قبل از زایمان - کاهش میزان کلسترول خون در موشهای صحرایی جنین ماده

Placental mechanism of prenatal nicotine exposure-reduced blood cholesterol levels in female fetal rats

Keywords: IUGR; intrauterine growth retardation; PNE; prenatal nicotine exposure; TCH; total cholesterol; HDL-C; high-density lipoprotein-cholesterol; LDL-C; low-density lipoprotein-cholesterol; SR-B1; scavenger receptor class B type 1; ABCA1; ATP-binding cassette

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

تاریخ طبیعی فیتوسترولیمی: مشاهدات در مورد آن در خانه است

The natural history of phytosterolemia: Observations on its homeostasis

Keywords: Rare disease; Sterol; Homeostasis; Sterol regulatory element binding protein-2; ABCG8; ATP-binding cassette sub-family G member 8; SREBP-2; Sterol regulatory element-binding protein 2; LDL; low-density lipoprotein; HMGCR; 3-Hydroxy-3-Methylglutaryl-CoA re

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2018 سفارش ترجمه

یک مدل ریاضی از پروتئین متصل کننده پروتئین استرول، پروتئین 2، پروتئین کلسترول

A mathematical model of the sterol regulatory element binding protein 2 cholesterol biosynthesis pathway

Keywords: Genetic regulation; Transcription factor; Nonlinear ordinary differential equation; SREBP-2;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

پوسته سیب زمینی بنفش سبب کاهش پروفایل لیپیدی سرم در موش هایی که دارای رژیم غذایی با کلسترول هستند

Purple potato flake reduces serum lipid profile in rats fed a cholesterol-rich diet

Keywords: ALP; alkaline phosphatase; ALT; alanine amino trasnferase; AST; aspartate amino trasnferase; CONT; a control diet; GAPDH; glyceraldehydes-3-phosphate dehydrogenase; HDL; high-density lipoprotein; HMG-CoA; 5-hydroxy-3-methylglutaryl-CoA; LDL; low-density l

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

MicroRNA-98 regulates hepatic cholesterol metabolism via targeting sterol regulatory element-binding protein 2

Keywords: MiR-98; Cholesterol metabolism; SREBP-2; HMG-CoA reductase;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2018 سفارش ترجمه

Long noncoding RNA lncARSR promotes hepatic cholesterol biosynthesis via modulating Akt/SREBP-2/HMGCR pathway

Keywords: lncARSR; Cholesterol; HMG-CoA reductase; SREBP-2; PI3K/Akt;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2018 سفارش ترجمه

Behavior of three hypocholesterolemic peptides from soy protein in an intestinal model based on differentiated Caco-2 cell

Keywords: Hypocholesterolemic peptides; Caco-2 cells; DPP-IV; HMGCoAR; In silico docking; Intestinal absorption; LC-MRM; Mass spectrometry; Soy protein; ACN; acetonitrile; AP; apical; BL; basolateral; CV; coefficient of variance; DMEM; Dulbecco's Modified Eagle M

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2018 سفارش ترجمه

Lysophosphatidylcholine induces expression of genes involved in cholesterol biosynthesis in THP-1 derived macrophages

Keywords: LPC; lysophosphatidylcholine; PCA; principal component analysis; FFA; free fatty acids; DMSO; dimethyl sulfoxide; FPKM; fragments per kilobase of transcript per million fragments mapped; RT-PCR; reverse transcription polymerase chain reaction; KEGG; Kyoto

دانلود رایگان متن کامل مقاله ISI 27 صفحه سال انتشار : 2018 سفارش ترجمه

DNA methylation signatures at endoplasmic reticulum stress genes are associated with adiposity and insulin resistance

Keywords: Endoplasmic reticulum; Epigenetics; Obesity; Triglycerides; Insulin resistance; BMI; body mass index; CASP12; caspase 12; CpG; cytosine-phosphate-guanine site; DBP; diastolic blood pressure; DiOGenes; diet obesity and genes dietary trial; DNAJC1; dnaJ hea

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2018 سفارش ترجمه

Cholesterol-lowering effect of Aralia elata (Miq.) Seem via the activation of SREBP-2 and the LDL receptor

Keywords: Aralia elata (Miq.) Seem; Cholesterol; HMG-CoA; LDL-R; SREBP-2;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2017 سفارش ترجمه

Cassia auriculata flower extract attenuates hyperlipidemia in male Wistar rats by regulating the hepatic cholesterol metabolism

Keywords: Et- CAF; ethanolic extract of Cassia auriculata flower; HMGR; HMG-CoA reductase; HMGS; HMGCoA synthase; SREBP-1c; sterol regulatory element binding protein -1c; SREBP-2; sterol regulatory element binding protein- 2; CYP7A1; cholesterol 7 α-hydroxylase; A

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2017 سفارش ترجمه

Neoagarooligosaccharides enhance the level and efficiency of LDL receptor and improve cholesterol homeostasis

Keywords: LDL cholesterol; LDL receptor; Neoagarooligosaccharides; PCSK9; SREBP-2; ALT; alanine aminotransferase; AOS; agaro-oligosaccharides; AST; aspartate aminotransferase; CHD; coronary heart disease; DNS; dinitrosalicylic acid; DP; degree of polymerization; HC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2017 سفارش ترجمه

New insights into cellular cholesterol acquisition: promoter analysis of human HMGCR and SQLE, two key control enzymes in cholesterol synthesis

Keywords: ChIP-seq; chromatin immunoprecipitation-sequencing; DHCR7; 7-dehydrocholesterol reductase; DHCR24; 24-dehydrocholesterol reductase; EMSA; electrophoretic mobility shift assay; FCLPDS; fetal calf lipoprotein-deficient serum; FCS; fetal calf serum; HMGCR; 3

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2017 سفارش ترجمه

NAFLD is associated with methylation shifts with relevance for the expression of genes involved in lipoprotein particle composition

Keywords: 1-25-diOH D; dihydroxyvitamine D; 25-OH D; 25-hydroxyvitamin D; APO; apolipoprotein; BMI; body mass index; ER; endoplasmic reticulum; FC; free cholesterol; FFAs; free fatty acids; FGF-2; fibroblast growth factor 2; FXRɑ; farnesoid X receptor α; HDL; hig

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2017 سفارش ترجمه

Double blind exploratory study on de novo lipogenesis in preterm infants on parenteral nutrition with a lipid emulsion containing 10% fish oil

Keywords: Lipids; Isotope labeling; Lipogenesis; Premature infants; Omega-3 fatty acids; Omega-6 fatty acids; ASR; absolute synthesis rate; CE; cholesterol esters; C16-CE; cholesterol esters palmitate; C16-PL; phospholipids palmitate; C16-TG; triglycerides palmitat

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Possible involvement of PCSK9 overproduction in hyperlipoproteinemia associated with hepatocellular carcinoma: A case report

Keywords: Hypercholesterolemia; Hypertriglyceridemia; Type III hyperlipoproteinemia; Cholesterol; Liver; Hepatocellular carcinoma; PCSK9; SREBP-2; LDL receptor; Hepatitis B virus;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

DHCR7: A vital enzyme switch between cholesterol and vitamin D production

Keywords: 7DHC; 7-dehydrocholesterol; AEBS; antiestrogen binding site; DHCR7; 7-dehydrocholesterol reductase; DHCR14; Δ14-sterol reductase; DHCR24; 24-dehydrocholesterol reductase; EBP; emopamil binding protein; Hh; Hedgehog; HMGCR; 3-hydroxy-3-methylglutaryl-CoA

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

Physiological feedback regulation of cholesterol biosynthesis: Role of translational control of hepatic HMG-CoA reductase and possible involvement of oxylanosterols

Keywords: HMG-CoA reductase; 3-hydroxy-3-methylgutaryl coenzyme A reductase; LDL; low density lipoprotein; HDL; high density lipoprotein; SRE; sterol response element; SREBP-2; sterol response element binding protein-2; Scap; SREBP cleavage-activating protein; Insi

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Alginate oligosaccharide enhances LDL uptake via regulation of LDLR and PCSK9 expression

Keywords: AOS; alginate oligosaccharide; CVD; cardiovascular disease; FH; familial hypercholesterolemia; GSK3β; glycogen synthase kinase 3β; HINFP; histone nuclear factor P; HMG-CoA; 3-hydroxy-3-methylglutaryl-coenzyme A; HNF; hepatocyte nuclear factor; Insig; in

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Enediynyl peptides and iso-coumarinyl methyl sulfones as inhibitors of proprotein convertases PCSK8/SKI-1/S1P and PCSK4/PC4: Design, synthesis and biological evaluations

Keywords: aa; amino acid; AMC; 7-amino 4-methyl coumarin; Amu; atomic mass unit; Au; arbitrary unit; Aufs; absorption units full scale; IMS; iso-coumarinyl methyl sulfone; Eda; enediyne amino acid; h; human; IC50; inhibitor concentration required for 50% inhibition

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

24S,25-Epoxycholesterol in mouse and rat brain

Keywords: HMG-CoA; 3-hydroxy-3-methyl-glutaryl-CoA; APCI; atmospheric pressure chemical ionisation; API; atmospheric pressure ionisation; BBB; blood brain barrier; CNS; central nervous system; Ctx; cortex; CYP or Cyp; cytochrome P450; DDA; data dependent analysis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Cholesterol-lowering effect of Lactobacillus plantarum NCU116 in a hyperlipidaemic rat model

Keywords: CVDs; cardiovascular diseases; CYP7A1; cholesterol 7α-hydroxylase; HDL-C; high-density lipoprotein cholesterol; HMG-CoA; 3-hydroxy-3-methylglutaryl coenzyme A; LDL-C; low-density lipoprotein cholesterol; SREBP-2; sterol regulatory element-binding protein

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

The sterol-based transcriptional control of human 7-dehydrocholesterol reductase (DHCR7): Evidence of a cooperative regulatory program in cholesterol synthesis

Keywords: 7DHC; 7-dehydrocholesterol; DHCR7; 7-dehydrocholesterol reductase; DHCR24; 24-dehydrocholesterol reductase; LDLR; low-density lipoprotein receptor; NF-Y; nuclear factor-Y; NPC1L1; Niemann-pick C1 like-1; SLOS; Smith-Lemli-Opitz Syndrome; Sp1; specific

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Accumulation of lipids and oxidatively damaged DNA in hepatocytes exposed to particles

Keywords: ABCG5; ATP-binding cassette, sub-family G (WHITE), member 5; ABCG8; ATP-binding cassette, sub-family G (WHITE), member 8; CB; carbon black; DEP; diesel exhaust particles; FASN; fatty acid synthase; FFA; free fatty acids; FPG; formamidopyrimidine DNA glyco

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Cholesterol biosynthesis and ER stress in peroxisome deficiency

Keywords: Peroxisomes; Cholesterol; Isoprenoid; Pex2; SREBP-2; ER stress; Integrated stress response; Unfolded protein response; Zellweger syndrome; ACAT; acetoacetyl-CoA thiolase; ATF; activating transcription factor; BA; bile acid; CHOP; C/EBP homologous protein;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Pectin pentasaccharide from hawthorn (Crataegus pinnatifida Bunge. Var. major) ameliorates disorders of cholesterol metabolism in high-fat diet fed mice

Keywords: HMGCR; 3-hydroxy-3-methyl-glutaryl-CoA reductase; SREBP-2; sterol regulatory element-binding protein 2; LDLR; low density lipoprotein receptor; CYP7A1; cholesterol 7α-hydroxylase; ACAT; acyl-coenzyme A: cholesterol acyl-transferase; Actb; actin beta; HPP

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Lipopolysaccharide downregulates CD91/low-density lipoprotein receptor-related protein 1 expression through SREBP-1 overexpression in human macrophages

Keywords: Lipopolysaccharide; Aggregated LDL; Human macrophages; LRP1; LDLR; SREBP-1; SREBP-2;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2013 سفارش ترجمه

Activation of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase during high fat diet feeding

Keywords: HMG-CoA reductase; Cholesterol; SREBP-2; Fatty liver

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2013 سفارش ترجمه

Acetoacetyl-CoA synthetase is essential for normal neuronal development

Keywords: Ketone body; SREBP-2; Acetoacetyl-CoA synthetase; Neuronal development

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

DPA n-3, DPA n-6 and DHA improve lipoprotein profiles and aortic function in hamsters fed a high cholesterol diet

Keywords: Docosahexaenoic acid; Docosapentaenoic acid; Total cholesterol; HMG-CoA reductase; SREBP-2; Vascular reactivity;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Acetoacetyl-CoA synthetase, a ketone body-utilizing enzyme, is controlled by SREBP-2 and affects serum cholesterol levels

Keywords: Ketone body; Cholesterol; SREBP-2; Acetoacetyl-CoA synthetase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Endoplasmic reticulum stress-mediated inhibition of NSMase2 elevates plasma membrane cholesterol and attenuates NO production in endothelial cells

Keywords: NO; nitric oxide; ER; endoplasmic reticulum; BAEC; bovine aortic endothelial cells; eNOS; endothelial nitric oxide synthase; NSMase or NSM; neutral sphingomyelinase; SREBP-2; sterol-responsive element-binding protein; Tm; tunicamycin; Pm; palmitate; RNAi;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Phaleria macrocarpa (Scheff.) Boerl fruit aqueous extract enhances LDL receptor and PCSK9 expression in vivo and in vitro

Keywords: apo-B; apolipoprotein B; BSA; bovine serum albumin; CETP; cholesterol ester transfer protein; HDL; high density lipoprotein; HMG-CoA; 3-hydroxy-3-methyl-glutaryl-CoA reductase; LDL; low density lipoprotein; PBS; phosphate buffer saline; PCSK9; proprotein

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2011 سفارش ترجمه

Hypocholesterolemic activity of grape seed proanthocyanidin is mediated by enhancement of bile acid excretion and up-regulation of CYP7A1

Keywords: Cholesterol; Grape seed proanthocyanidin; CYP7A1; LDL receptor; HMG-CoA reductase; SREBP-2; Liver X receptor

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Activation of TM7SF2 promoter by SREBP-2 depends on a new sterol regulatory element, a GC-box, and an inverted CCAAT-box

Keywords: SRE; sterol regulatory element; SREBP-2; SRE-binding protein 2; NF-Y; nuclear factor Y; LDLR; low density lipoprotein receptor; FBS; foetal bovine serum; Lov; lovastatin; 25-OH chol; 25-hydroxycholesterol; LPDS; lipoprotein deficient serum; EMSA; electrop

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

Selective role of sterol regulatory element binding protein isoforms in aggregated LDL-induced vascular low density lipoprotein receptor-related protein-1 expression

Keywords: Aggregated LDL; LRP1; SREBP-1a; SREBP-1c; SREBP-2; Human VSMC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

Pitavastatin induces PON1 expression through p44/42 mitogen-activated protein kinase signaling cascade in Huh7 cells

Keywords: Paraoxonase; HMG-CoA reductase inhibitor; ERK; SREBP-2; Sp1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Regulation of steroid 5-α reductase type 2 (Srd5a2) by sterol regulatory element binding proteins and statin

Keywords: Srd5a2; Steroid 5-α reductase type 2; SREBP; sterol regulatory element binding protein; HMG; 3-hydroxy-3-methylglutaryl; ChIP; chromatin immunoprecipitation; qPCR; quantitative PCR; L/E; lovastatin and ezetimibe; LDLR; low density lipoprotein receptor; S

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Localization of the transcription factor, sterol regulatory element binding protein-2 (SREBP-2) in the normal rat brain and changes after kainate-induced excitotoxic injury

Keywords: SREBP-2; Hippocampus; Cerebral cortex; Striatum; Dendrites; Cholesterol biosynthesis; Excitotoxicity

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Enhanced free cholesterol, SREBP-2 and StAR expression in human NASH

Keywords: NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; FFA; free fatty acids; TG; triglycerides; SREBP-2; sterol regulatory element-binding protein-2; SREBP-1c; sterol regulatory element-binding protein-1c; HMG-CoA reductase; hydro

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2009 سفارش ترجمه

Inhibitory effect of novel diallyldisulfide analogs on HMG-CoA reductase expression in hypercholesterolemic rats: CREB as a potential upstream target

Keywords: Diallyldisulfide; HMG-CoA reductase; SREBP-2; CREB; NF-Y; NF-κB

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Rapamycin down-regulates LDL-receptor expression independently of SREBP-2

Keywords: SREBP-2; Rapamycin; Sirolimus; mTOR; LDL-receptor; Hyperlipidemia;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

Overexpression of A-kinase anchoring protein 12A activates sterol regulatory element binding protein-2 and enhances cholesterol efflux in hepatic cells

Keywords: AKAP12/Gravin; SREBP-2; Cholesterol; U18666A; Cholesterol efflux

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Inability to fully suppress sterol synthesis rates with exogenous sterol in embryonic and extraembyronic fetal tissues

Keywords: SLOS; Smith-Lemli-Opitz syndrome; DHCR7; 3β-hydroxysterol Δ7-reductase; HMGR; HMG-CoA reductase; SREBP; sterol regulatory element binding protein; SCAP; SREBP cleavage-activating protein; DPS; digitonin-precipitable sterols; Shh; Sonic hedgehog; Cho

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Activation of the hepatic LDL receptor promoter by thyroid hormone

Keywords: LDL receptor promoter activity; Cholesterol domeostasis; Thyroid hormone response element; Rat liver; Thyroid receptor β1; SREBP-2; Sterol response element

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

LDL receptor gene transcription is selectively induced by t10c12-CLA but not by c9t11-CLA in the human hepatoma cell line HepG2

Keywords: CLA, conjugated linoleic acid; LA, linoleic acid; SREBP, sterol regulatory element binding protein; HMG-CoA reductase, 3-hydroxy-3-methylglutaryl-coenzyme A reductaseConjugated linoleic acid; LDL receptor; Atherosclerosis; SREBP-2; SREBP-1

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2006 سفارش ترجمه

Sterol Regulatory Element-binding Protein-2 Negatively Regulates Low Density Lipoprotein Receptor-related Protein Transcription

Keywords: LRP1; SREBP-2; down-regulationLDL, low density lipoprotein; agLDL, aggregated LDL; LDLR, LDL receptor; SRE, sterol regulatory element; SREBP-2, sterol regulatory element binding protein; VSMC, vascular smooth muscle cells; LRP1, low density lipoprotein re

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه