Rotigotine transdermal patch in Chinese patients with advanced Parkinson's disease: A randomized, double-blind, placebo-controlled pivotal study Fulltext Access 26 Pages 2017
Structural and functional alterations associated with deutan N94K and R330Q mutations of green cone opsin Fulltext Access 26 Pages 2017
Quantitative assessment of autonomic symptom burden in Postural tachycardia syndrome (POTS) Fulltext Access 26 Pages 2017
Autophagy suppresses isoprenaline-induced M2 macrophage polarization via the ROS/ERK and mTOR signaling pathway Fulltext Access 26 Pages 2017
Oxidant species are involved in T/B-mediated ERK1/2 phosphorylation that activates p53-p21 axis to promote KSHV lytic cycle in PEL cells Fulltext Access 26 Pages 2017
Fluorescent proteins such as eGFP lead to catalytic oxidative stress in cells Fulltext Access 26 Pages 2017
Low energy costs of F1Fo ATP synthase reversal in colon carcinoma cells deficient in mitochondrial complex IV Fulltext Access 26 Pages 2017
Ablation of systemic SIRT1 activity promotes nonalcoholic fatty liver disease by affecting liver-mesenteric adipose tissue fatty acid mobilization Fulltext Access 26 Pages 2017
Xanthohumol isolated from Humulus lupulus prevents thrombosis without increased bleeding risk by inhibiting platelet activation and mtDNA release Fulltext Access 26 Pages 2017
The miRNome of Alzheimer's disease: consistent downregulation of the miR-132/212 cluster Fulltext Access 26 Pages 2017
C-reactive protein is related to future cognitive impairment and decline in elderly individuals with cardiovascular disease Fulltext Access 26 Pages 2017
Identification of post-translational modifications of Aβ peptide in platelet membranes from patients with cerebral amyloid angiopathy Fulltext Access 27 Pages 2017
Fructose induced neurogenic hypertension mediated by overactivation of p38 MAPK to impair insulin signaling transduction caused central insulin resistance Fulltext Access 27 Pages 2017
Involvement of tRNAs in replication of human mitochondrial DNA and modifying effects of telomerase Fulltext Access 27 Pages 2017
Insulin-dependent metabolic and inotropic responses in the heart are modulated by hydrogen peroxide from NADPH-oxidase isoforms NOX2 and NOX4 Fulltext Access 27 Pages 2017
ER stress disturbs SR/ER-mitochondria Ca2Â + transfer: Implications in Duchenne muscular dystrophy Fulltext Access 27 Pages 2017
Cholesterol regulates DAF-16 nuclear localization and fasting-induced longevity in C. elegans Fulltext Access 27 Pages 2017
Identifying combinatorial biomarkers by association rule mining in the CAMD Alzheimer's database Fulltext Access 27 Pages 2017
Parkinson's disease-associated pathogenic VPS35 mutation causes complex I deficits Fulltext Access 27 Pages 2017
RAGE deficiency alleviates aortic valve calcification in ApoEâ/â mice via the inhibition of endoplasmic reticulum stress Fulltext Access 27 Pages 2017
Effects of learning on mTOR pathway gene expression in the brain of zebrafish (Danio rerio) of different ages Fulltext Access 27 Pages 2017
The ataxia related G1107D mutation of the plasma membrane Ca2Â + ATPase isoform 3 affects its interplay with calmodulin and the autoinhibition process Fulltext Access 27 Pages 2017
The anti-aging and anti-oxidation effects of tea water extract in Caenorhabditis elegans Fulltext Access 27 Pages 2017
Inactivation of glycogen synthase kinase-3β (GSK-3β) enhances skeletal muscle oxidative metabolism Fulltext Access 27 Pages 2017
DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression Fulltext Access 27 Pages 2017
Trans-crocetin improves amyloid-β degradation in monocytes from Alzheimer's Disease patients Fulltext Access 27 Pages 2017
GRN deletion in familial frontotemporal dementia showing association with clinical variability in 3 familial cases Fulltext Access 27 Pages 2017
A novel mutation in TREM2 gene causing Nasu-Hakola disease and review of the literature Fulltext Access 27 Pages 2017
Transcriptome-wide piRNA profiling in human brains of Alzheimer's disease Fulltext Access 27 Pages 2017
Protective effects of ginsenoside Rg1 against oxygen-glucose-deprivation-induced apoptosis in neural stem cells Fulltext Access 27 Pages 2017
Triggering autophagic cell death with a di-manganese(II) developmental therapeutic Fulltext Access 27 Pages 2017
Clinical, imaging, pathological, and biochemical characterization of a novel presenilin 1 mutation (N135Y) causing Alzheimer's disease Fulltext Access 27 Pages 2017
Dexibuprofen prevents neurodegeneration and cognitive decline in APPswe/PS1dE9 through multiple signaling pathways Fulltext Access 27 Pages 2017
Serum C-peptide as a key contributor to lipid-related residual cardiovascular risk in the elderly Fulltext Access 27 Pages 2017
MicroRNA-194 inhibition improves dietary-induced non-alcoholic fatty liver disease in mice through targeting on FXR Fulltext Access 27 Pages 2017
Na+/K+-ATPase interaction with methylglyoxal as reactive metabolic side product Fulltext Access 28 Pages 2017
Zinc regulates Nox1 expression through a NF-κB and mitochondrial ROS dependent mechanism to induce senescence of vascular smooth muscle cells Fulltext Access 28 Pages 2017
A novel PMCA3 mutation in an ataxic patient with hypomorphic phosphomannomutase 2 (PMM2) heterozygote mutations: Biochemical characterization of the pump defect Fulltext Access 28 Pages 2017
Role of vitamin A metabolism in IIH: Results from the idiopathic intracranial hypertension treatment trial Fulltext Access 28 Pages 2017
Contribution to Alzheimer's disease risk of rare variants in TREM2, SORL1, and ABCA7 in 1779 cases and 1273 controls Fulltext Access 28 Pages 2017
In vivo assessment of iron content of the cerebral cortex in healthy aging using 7-Tesla T2*-weighted phase imaging Fulltext Access 28 Pages 2017
A gene-environment interaction analysis of plasma selenium with prevalent and incident diabetes: The Hortega study Fulltext Access 28 Pages 2017
Fetuin-A downregulates adiponectin through Wnt-PPARγ pathway in lipid induced inflamed adipocyte Fulltext Access 28 Pages 2017
Mouse lysine catabolism to aminoadipate occurs primarily through the saccharopine pathway; implications for pyridoxine dependent epilepsy (PDE) Fulltext Access 28 Pages 2017
Decreased gene expression of CD2AP in Chinese patients with sporadic Alzheimer's disease Fulltext Access 28 Pages 2017
Measures of impulsivity in Parkinson's disease decrease after DBS in the setting of stable dopamine therapy Fulltext Access 28 Pages 2017
α-Dystroglycan hypoglycosylation affects cell migration by influencing β-dystroglycan membrane clustering and filopodia length: A multiscale confocal microscopy analysis Fulltext Access 28 Pages 2017
Novel mutation in mitochondrial Elongation Factor EF-Tu associated to dysplastic leukoencephalopathy and defective mitochondrial DNA translation Fulltext Access 28 Pages 2017
Metabonomics approach to assessing the metabolism variation and gender gap of Drosophila melanogaster in aging process Fulltext Access 29 Pages 2017
Apigenin attenuates isoflurane-induced cognitive dysfunction via epigenetic regulation and neuroinflammation in aged rats Fulltext Access 29 Pages 2017
Cellular adaptation to xenobiotics: Interplay between xenosensors, reactive oxygen species and FOXO transcription factors Fulltext Access 29 Pages 2017
Heme modulates Trypanosoma cruzi bioenergetics inducing mitochondrial ROS production Fulltext Access 29 Pages 2017
Relationship of the angle between the A1 and A2 segments of the anterior cerebral artery with formation and rupture of anterior communicating artery aneurysm Fulltext Access 29 Pages 2017
Oxidative stress, mitochondrial abnormalities and antioxidant defense in Ataxia-telangiectasia, Bloom syndrome and Nijmegen breakage syndrome Fulltext Access 29 Pages 2017
Klotho, APOEε4, cognitive ability, brain size, atrophy, and survival: a study in the Aberdeen Birth Cohort of 1936 Fulltext Access 29 Pages 2017
Potential role of lycopene in targeting proprotein convertase subtilisin/kexin type-9 to combat hypercholesterolemia Fulltext Access 29 Pages 2017
Predicting 3-year mortality and admission to acute-care hospitals, skilled nursing facilities, and long-term care facilities in Medicare beneficiaries Fulltext Access 29 Pages 2017
ER fatalities-The role of ER-mitochondrial contact sites in yeast life and death decisions Fulltext Access 29 Pages 2017
Epigenetic regulation of EC-SOD expression in aging lung fibroblasts: Role of histone acetylation Fulltext Access 29 Pages 2017
Targeted downregulation of dMyc restricts neurofibrillary tangles mediated pathogenesis of human neuronal tauopathies in Drosophila Fulltext Access 29 Pages 2017
Experimental Guillain-Barre syndrome induced by immunization with gangliosides: Keyhole limpet hemocyanin is required for disease triggering Fulltext Access 29 Pages 2017
Mitochondrial defects arise from nucleoside/nucleotide reverse transcriptase inhibitors in neurons: Potential contribution to HIV-associated neurocognitive disorders Fulltext Access 29 Pages 2017
Severe fluoropyrimidine toxicity due to novel and rare DPYD missense mutations, deletion and genomic amplification affecting DPD activity and mRNA splicing Fulltext Access 29 Pages 2017
The addition of ketone bodies alleviates mitochondrial dysfunction by restoring complex I assembly in a MELAS cellular model Fulltext Access 29 Pages 2017
CREG protects from myocardial ischemia/reperfusion injury by regulating myocardial autophagy and apoptosis Fulltext Access 29 Pages 2017
Epigenetic and gene expression alterations of FOXP3 in the T cells of EAE mouse model of multiple sclerosis Fulltext Access 30 Pages 2017
Novel patient missense mutations in the HSD17B10 gene affect dehydrogenase and mitochondrial tRNA modification functions of the encoded protein Fulltext Access 30 Pages 2017
Increased serotransferrin and ceruloplasmin turnover in diet-controlled patients with type 2 diabetes Fulltext Access 30 Pages 2017
Synergistic enhancement of topotecan-induced cell death by ascorbic acid in human breast MCF-7 tumor cells Fulltext Access 30 Pages 2017
Insulin-like growth factor-1 protects SH-SY5Y cells against β-amyloid-induced apoptosis via the PI3K/Akt-Nrf2 pathway Fulltext Access 30 Pages 2017
Survivin controls biogenesis of microRNA in smokers: A link to pathogenesis of rheumatoid arthritis Fulltext Access 30 Pages 2017
CSF/serum albumin ratio in dementias: a cross-sectional study on 1861 patients Fulltext Access 30 Pages 2017
Alteration of methylation status in the ATXN3 gene promoter region is linked to the SCA3/MJD Fulltext Access 30 Pages 2017
Association of anti-inflammatory cytokine IL10 polymorphisms with motoric cognitive risk syndrome in an Ashkenazi Jewish population Fulltext Access 30 Pages 2017
Quantitative EEG during normal aging: association with the Alzheimer's disease genetic risk variant in PICALM gene Fulltext Access 30 Pages 2017
Serum miRNAs miR-206, 143-3p and 374b-5p as potential biomarkers for amyotrophic lateral sclerosis (ALS) Fulltext Access 30 Pages 2017
Genetic and functional analysis of TBK1 variants in Korean patients with sporadic amyotrophic lateral sclerosis Fulltext Access 30 Pages 2017
Frail elderly with and without cognitive impairment at the end of life: Their emotional state and the wellbeing of their family caregivers Fulltext Access 30 Pages 2017
Epinecidin-1 protects mice from LPS-induced endotoxemia and cecal ligation and puncture-induced polymicrobial sepsis Fulltext Access 30 Pages 2017
Hepatic stellate cell-specific deletion of SIRT1 exacerbates liver fibrosis in mice Fulltext Access 30 Pages 2017
Low concentration of uncouplers of oxidative phosphorylation decreases the TNF-induced endothelial permeability and lethality in mice Fulltext Access 30 Pages 2017
Evening and morning peroxiredoxin-2 redox/oligomeric state changes in obstructive sleep apnea red blood cells: Correlation with polysomnographic and metabolic parameters Fulltext Access 30 Pages 2017
Long-term safety of repeated high doses of incobotulinumtoxinA injections for the treatment of upper and lower limb spasticity after stroke Fulltext Access 30 Pages 2017
Search for KPNA7 cargo proteins in human cells reveals MVP and ZNF414 as novel regulators of cancer cell growth Fulltext Access 30 Pages 2017
Dried plum and chokeberry ameliorate d-galactose-induced aging in mice by regulation of Pl3k/Akt-mediated Nrf2 and Nf-kB pathways Fulltext Access 30 Pages 2017
Common variants of human TERT and TERC genes and susceptibility to sporadic Alzheimers disease Fulltext Access 30 Pages 2017
A role of BAG3 in regulating SNCA/α-synuclein clearance via selective macroautophagy Fulltext Access 30 Pages 2017
Lethal dysregulation of energy metabolism during embryonic vitamin E deficiency Fulltext Access 30 Pages 2017
PARP inhibition protects mitochondria and reduces ROS production via PARP-1-ATF4-MKP-1-MAPK retrograde pathway Fulltext Access 30 Pages 2017
Down-regulation of NOX2 activity in phagocytes mediated by ATM-kinase dependent phosphorylation Fulltext Access 31 Pages 2017
Theaflavin ameliorates ionizing radiation-induced hematopoietic injury via the NRF2 pathway Fulltext Access 31 Pages 2017
Portacaval shunting causes differential mitochondrial superoxide production in brain regions Fulltext Access 31 Pages 2017
Loss of Nrf2 promotes alveolar type 2 cell loss in irradiated, fibrotic lung Fulltext Access 31 Pages 2017