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Daneshyari Ageing Journas Latest Articles

Ageing Research Articles

BMP7-induced-Pten inhibits Akt and prevents renal fibrosis
Fulltext Access 35 Pages 2017
Aquaporin-3 deletion in mice results in renal collecting duct abnormalities and worsens ischemia-reperfusion injury
Fulltext Access 35 Pages 2017
Ketogenic diet leads to O-GlcNAc modification in the BTBRT + tf/j mouse model of autism
Fulltext Access 35 Pages 2017
Redox modification of caveolar proteins in the cardiovascular system- role in cellular signalling and disease
Fulltext Access 35 Pages 2017
Modeling schizophrenia pathogenesis using patient-derived induced pluripotent stem cells (iPSCs)
Fulltext Access 35 Pages 2017
Profibrotic IHG-1 complexes with renal disease associated HSPA5 and TRAP1 in mitochondria
Fulltext Access 35 Pages 2017
A novel role of topical iodine in skin: Activation of the Nrf2 pathway
Fulltext Access 35 Pages 2017
Structural basis, chemical driving forces and biological implications of flavones as Cu(II) ionophores
Fulltext Access 35 Pages 2017
Altered expression of E-Cadherin-related transcription factors indicates partial epithelial-mesenchymal transition in aggressive meningiomas
Fulltext Access 35 Pages 2017
Caloric restriction protects livers from ischemia/reperfusion damage by preventing Ca2+-induced mitochondrial permeability transition
Fulltext Access 35 Pages 2017
Deletion of CD73 in mice leads to aortic valve dysfunction
Fulltext Access 35 Pages 2017
Insights into the differential toxicological and antioxidant effects of 4-phenylchalcogenil-7-chloroquinolines in Caenorhabditis elegans
Fulltext Access 35 Pages 2017
Functional characterisation of the methionine sulfoxide reductase repertoire in Trypanosoma brucei
Fulltext Access 35 Pages 2017
NADPH oxidases as drug targets and biomarkers in neurodegenerative diseases: What is the evidence?
Fulltext Access 35 Pages 2017
Proteomic analysis of the glutathione-deficient LEGSKO mouse lens reveals activation of EMT signaling, loss of lens specific markers, and changes in stress response proteins
Fulltext Access 35 Pages 2017
Inhibition of hepatocyte nuclear factor 1b induces hepatic steatosis through DPP4/NOX1-mediated regulation of superoxide
Fulltext Access 35 Pages 2017
The protective properties of Act-Belong-Commit indicators against incident depression, anxiety, and cognitive impairment among older Irish adults: Findings from a prospective community-based study
Fulltext Access 35 Pages 2017
Exercise increases mitochondrial complex I activity and DRP1 expression in the brains of aged mice
Fulltext Access 36 Pages 2017
Synthesis of l-cysteine derivatives containing stable sulfur isotopes and application of this synthesis to reactive sulfur metabolome
Fulltext Access 36 Pages 2017
Novel molecular insights into the function and the antioxidative stress response of a Peroxiredoxin Q protein from cyanobacteria
Fulltext Access 36 Pages 2017
Chronic vitamin E deficiency impairs cognitive function in adult zebrafish via dysregulation of brain lipids and energy metabolism
Fulltext Access 36 Pages 2017
Neocortical and hippocampal TREM2 protein levels during the progression of Alzheimer's disease
Fulltext Access 36 Pages 2017
An mtDNA mutation accelerates liver aging by interfering with the ROS response and mitochondrial life cycle
Fulltext Access 36 Pages 2017
Carnosic acid (CA) attenuates collagen-induced arthritis in db/db mice via inflammation suppression by regulating ROS-dependent p38 pathway
Fulltext Access 36 Pages 2017
Effects of left DLPFC versus right PPC tDCS on multiple sclerosis fatigue
Fulltext Access 36 Pages 2017
Drug holidays from bisphosphonates and denosumab in postmenopausal osteoporosis: EMAS position statement
Fulltext Access 36 Pages 2017
Retinal neurodegeneration and brain MRI markers: the Rotterdam Study
Fulltext Access 36 Pages 2017
Non-oxidizable HMGB1 induces cardiac fibroblasts migration via CXCR4 in a CXCL12-independent manner and worsens tissue remodeling after myocardial infarction
Fulltext Access 36 Pages 2017
Ethanol-induced PGE2 up-regulates Aβ production through PKA/CREB signaling pathway
Fulltext Access 36 Pages 2017
Impact of aging on distribution of IgA+ and IgG+ cells in aggregated lymphoid nodules area in abomasum of Bactrian camels (Camelus bactrianus)
Fulltext Access 36 Pages 2017
Decreasing body mass index is associated with cerebrospinal fluid markers of Alzheimer's pathology in MCI and mild dementia
Fulltext Access 36 Pages 2017
Extracellular miR-145, miR-223 and miR-326 expression signature allow for differential diagnosis of immune-mediated neuroinflammatory diseases
Fulltext Access 36 Pages 2017
Levodopa-carbidopa intestinal gel in advanced Parkinson's: Final results of the GLORIA registry
Fulltext Access 36 Pages 2017
Role of p16INK4a and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells
Fulltext Access 36 Pages 2017
Applicability of [11C]PIB micro-PET imaging for in vivo follow-up of anti-amyloid treatment effects in APP23 mouse model
Fulltext Access 36 Pages 2017
MDH2 is an RNA binding protein involved in downregulation of sodium channel Scn1a expression under seizure condition
Fulltext Access 36 Pages 2017
Downregulation of miR-132/212 impairs S-nitrosylation balance and induces tau phosphorylation in Alzheimer's disease
Fulltext Access 36 Pages 2017
Dual role of MUC1 mucin in kidney ischemia-reperfusion injury: Nephroprotector in early phase, but pro-fibrotic in late phase
Fulltext Access 36 Pages 2017
The role of miR-190a in methylglyoxal-induced insulin resistance in endothelial cells
Fulltext Access 36 Pages 2017
High-sucrose-induced maternal obesity disrupts ovarian function and decreases fertility in Drosophila melanogaster
Fulltext Access 36 Pages 2017
Medial temporal lobe subregional morphometry using high resolution MRI in Alzheimer's disease
Fulltext Access 36 Pages 2017
Early upregulation of 18-kDa translocator protein in response to acute neurodegenerative damage in TREM2-deficient mice
Fulltext Access 36 Pages 2017
miR-4516, a microRNA downregulated in psoriasis inhibits keratinocyte motility by targeting fibronectin/integrin α9 signaling
Fulltext Access 36 Pages 2017
Foxo3a inhibits mitochondrial fission and protects against doxorubicin-induced cardiotoxicity by suppressing MIEF2
Fulltext Access 37 Pages 2017
Aging, microglia and cytoskeletal regulation are key factors in the pathological evolution of the APP23 mouse model for Alzheimer's disease
Fulltext Access 37 Pages 2017
Oxidative stress and pro-inflammatory cytokines may act as one of the signals for regulating microRNAs expression in Alzheimer's disease
Fulltext Access 37 Pages 2017
Thyroid nodules: Α guide to assessment, treatment and follow-up
Fulltext Access 37 Pages 2017
Autophagy, its mechanisms and regulation: Implications in neurodegenerative diseases
Fulltext Access 37 Pages 2017
Self-rated health and all-cause and cause-specific mortality of older adults: Individual data meta-analysis of prospective cohort studies in the CHANCES Consortium
Fulltext Access 37 Pages 2017
The GABAergic septohippocampal connection is impaired in a mouse model of tauopathy
Fulltext Access 37 Pages 2017
Cortical control of vertical and horizontal saccades in progressive supranuclear palsy: An exploratory fMRI study
Fulltext Access 37 Pages 2017
Piperlongumine attenuates experimental autoimmune encephalomyelitis through inhibition of NF-kappaB activity
Fulltext Access 37 Pages 2017
DHA-derived oxylipins, neuroprostanes and protectins, differentially and dose-dependently modulate the inflammatory response in human macrophages: Putative mechanisms through PPAR activation
Fulltext Access 37 Pages 2017
Reactive oxygen species enhance mitochondrial function, insulin sensitivity and glucose uptake in skeletal muscle of senescence accelerated prone mice SAMP8
Fulltext Access 37 Pages 2017
Enhancing Mitofusin/Marf ameliorates neuromuscular dysfunction in Drosophila models of TDP-43 proteinopathies
Fulltext Access 37 Pages 2017
HMGB1-RAGE pathway drives peroxynitrite signaling-induced IBD-like inflammation in murine nonalcoholic fatty liver disease
Fulltext Access 37 Pages 2017
Interleukin-6 and neuregulin-1 as regulators of utrophin expression via the activation of NRG-1/ErbB signaling pathway in mdx cells
Fulltext Access 37 Pages 2017
Genetic variation in WRN and ischemic stroke: General population studies and meta-analyses
Fulltext Access 37 Pages 2017
Impact of β-hydroxy β-methylbutyrate (HMB) on age-related functional deficits in mice
Fulltext Access 37 Pages 2017
Vitamin D and walking speed in older adults: Systematic review and meta-analysis
Fulltext Access 37 Pages 2017
CHAC2 is essential for self-renewal and glutathione maintenance in human embryonic stem cells
Fulltext Access 37 Pages 2017
Dimerization and oxidation of tryptophan in UV-A photolysis sensitized by kynurenic acid
Fulltext Access 37 Pages 2017
The peroxyl radical-induced oxidation of Escherichia coli FtsZ and its single tryptophan mutant (Y222W) modifies specific side-chains, generates protein cross-links and affects biological function
Fulltext Access 37 Pages 2017
Analysis of endogenous H2S and H2Sn in mouse brain by high-performance liquid chromatography with fluorescence and tandem mass spectrometric detection
Fulltext Access 37 Pages 2017
Amyloid and intracellular accumulation of BRI2
Fulltext Access 37 Pages 2017
Thalamic DBS with a constant-current device in essential tremor: A controlled clinical trial
Fulltext Access 38 Pages 2017
Walking speed decline in older adults is associated with elevated pro-BDNF in plasma extracellular vesicles
Fulltext Access 38 Pages 2017
iNOS-derived peroxynitrite mediates high glucose-induced inflammatory gene expression in vascular smooth muscle cells through promoting KLF5 expression and nitration
Fulltext Access 38 Pages 2017
Modulation of dendritic cell and T cell cross-talk during aging: The potential role of checkpoint inhibitory molecules
Fulltext Access 38 Pages 2017
N-type Ca2+ channels are affected by full-length mutant huntingtin expression in a mouse model of Huntington's disease
Fulltext Access 38 Pages 2017
Structural determinants in ApoA-I amyloidogenic variants explain improved cholesterol metabolism despite low HDL levels
Fulltext Access 38 Pages 2017
Non-linear impact of glutathione depletion on C. elegans life span and stress resistance
Fulltext Access 38 Pages 2017
Polytrauma-induced hepatic stress response and the development of liver insulin resistance
Fulltext Access 38 Pages 2017
IGF-1R signalling contributes to IL-6 production and T cell dependent inflammation in rheumatoid arthritis
Fulltext Access 38 Pages 2017
DMAPT inhibits NF-κB activity and increases sensitivity of prostate cancer cells to X-rays in vitro and in tumor xenografts in vivo
Fulltext Access 38 Pages 2017
Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway
Fulltext Access 38 Pages 2017
Classical transient receptor potential 6 (TRPC6) channels support myofibroblast differentiation and development of experimental pulmonary fibrosis
Fulltext Access 38 Pages 2017
Regulatory roles of glutathione-S-transferases and 4-hydroxynonenal in stress-mediated signaling and toxicity
Fulltext Access 38 Pages 2017
TNAP stimulates vascular smooth muscle cell trans-differentiation into chondrocytes through calcium deposition and BMP-2 activation: Possible implication in atherosclerotic plaque stability
Fulltext Access 38 Pages 2017
Characterization of phospholipid nitroxidation by LC-MS in biomimetic models and in H9c2 Myoblast using a lipidomic approach
Fulltext Access 38 Pages 2017
Polydatin promotes Nrf2-ARE anti-oxidative pathway through activating CKIP-1 to resist HG-induced up-regulation of FN and ICAM-1 in GMCs and diabetic mice kidneys
Fulltext Access 38 Pages 2017
1,4-Naphthoquinone activates the HSP90/HSF1 pathway through the S-arylation of HSP90 in A431 cells: Negative regulation of the redox signal transduction pathway by persulfides/polysulfides
Fulltext Access 38 Pages 2017
The p7 viroporin of the hepatitis C virus contributes to liver inflammation by stimulating production of Interleukin-1β
Fulltext Access 38 Pages 2017
PPARα activation by MHY908 attenuates age-related renal inflammation through modulation of the ROS/Akt/FoxO1 pathway
Fulltext Access 38 Pages 2017
Ageing is not associated with an altered immune response during Trypanosoma cruzi infection
Fulltext Access 38 Pages 2017
Nuclear protein HMGN2 attenuates pyocyanin-induced oxidative stress via Nrf2 signaling and inhibits Pseudomonas aeruginosa internalization in A549 cells
Fulltext Access 38 Pages 2017
The effect of exercise, resveratrol or their combination on Sarcopenia in aged rats via regulation of AMPK/Sirt1 pathway
Fulltext Access 38 Pages 2017
Relationship of angiotensin I-converting enzyme (ACE) and bradykinin B2 receptor (BDKRB2) polymorphism with diabetic nephropathy
Fulltext Access 39 Pages 2017
The effects of PPARγ on the regulation of the TOMM40-APOE-C1 genes cluster
Fulltext Access 39 Pages 2017
Hydrogen peroxide, nitric oxide and ATP are molecules involved in cardiac mitochondrial biogenesis in Diabetes
Fulltext Access 39 Pages 2017
Mdivi-1 ameliorates early brain injury after subarachnoid hemorrhage via the suppression of inflammation-related blood-brain barrier disruption and endoplasmic reticulum stress-based apoptosis
Fulltext Access 39 Pages 2017
The biological foundation of the genetic association of TOMM40 with late-onset Alzheimer's disease
Fulltext Access 39 Pages 2017
Role of membrane GM1 on early neuronal membrane actions of Aβ during onset of Alzheimer's disease
Fulltext Access 39 Pages 2017
Upregulation of Akt signaling enhances femoral fracture healing by accelerating atrophic quadriceps recovery
Fulltext Access 39 Pages 2017
Hypotensive and vasorelaxant effect of Diapocynin in normotensive rats
Fulltext Access 39 Pages 2017
Role of PARP-1 as a novel transcriptional regulator of MMP-9 in diabetic retinopathy
Fulltext Access 39 Pages 2017
Regulated expression of the TPβ isoform of the human T prostanoid receptor by the tumour suppressors FOXP1 and NKX3.1: Implications for the role of thromboxane in prostate cancer
Fulltext Access 39 Pages 2017
Fecal microbiota transplantation (FMT) could reverse the severity of experimental necrotizing enterocolitis (NEC) via oxidative stress modulation
Fulltext Access 39 Pages 2017
Methylglyoxal-induced AMPK activation leads to autophagic degradation of thioredoxin 1 and glyoxalase 2 in HT22 nerve cells
Fulltext Access 39 Pages 2017
Inhibition of Drp1-mediated mitochondrial fission improves mitochondrial dynamics and bioenergetics stimulating neurogenesis in hippocampal progenitor cells from a Down syndrome mouse model
Fulltext Access 39 Pages 2017
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