Elevated glutaric acid levels in Dhtkd1-/Gcdh- double knockout mice challenge our current understanding of lysine metabolism Fulltext Access 31 Pages 2017
Cyclophosphamide and acrolein induced oxidative stress leading to deterioration of metaphase II mouse oocyte quality Fulltext Access 31 Pages 2017
Connexin43 regulates high glucose-induced expression of fibronectin, ICAM-1 and TGF-β1 via Nrf2/ARE pathway in glomerular mesangial cells Fulltext Access 31 Pages 2017
Social regulation of ageing by young workers in the honey bee, Apis mellifera Fulltext Access 31 Pages 2017
In vivo EPR pharmacokinetic evaluation of the redox status and the blood brain barrier permeability in the SOD1G93A ALS rat model Fulltext Access 31 Pages 2017
Berberine improves cognitive impairment by promoting autophagic clearance and inhibiting production of β-amyloid in APP/tau/PS1 mouse model of Alzheimer's disease Fulltext Access 31 Pages 2017
CSF protein changes associated with hippocampal sclerosis risk gene variants highlight impact of GRN/PGRN Fulltext Access 31 Pages 2017
Uncoupling of oxidative stress resistance and lifespan in long-lived isp-1 mitochondrial mutants in Caenorhabditis elegans Fulltext Access 31 Pages 2017
Association of Ambulatory Blood Pressure Monitoring parameters with the Framingham Stroke Risk Profile Fulltext Access 31 Pages 2017
Anhedonia and its correlation with clinical aspects in Parkinson's disease Fulltext Access 31 Pages 2017
Fanconi Anemia: A DNA repair disorder characterized by accelerated decline of the hematopoietic stem cell compartment and other features of aging Fulltext Access 31 Pages 2017
The methylation of nuclear and mitochondrial DNA in ageing phenotypes and longevity Fulltext Access 31 Pages 2017
Life and death in the trash heap: The ubiquitin proteasome pathway and UCHL1 in brain aging, neurodegenerative disease and cerebral Ischemia Fulltext Access 31 Pages 2017
3T hippocampal glutamate-glutamine complex reflects verbal memory decline in aging Fulltext Access 31 Pages 2017
Polynucleotide kinase-phosphatase (PNKP) mutations and neurologic disease Fulltext Access 31 Pages 2017
Burden of rare variants in ALS genes influences survival in familial and sporadic ALS Fulltext Access 31 Pages 2017
Traffic-related air pollution impact on mouse brain accelerates myelin and neuritic aging changes with specificity for CA1 neurons Fulltext Access 31 Pages 2017
Radiation-induced DNA-protein cross-links: Mechanisms and biological significance Fulltext Access 32 Pages 2017
Mechanism of synergistic DNA damage induced by the hydroquinone metabolite of brominated phenolic environmental pollutants and Cu(II): Formation of DNA-Cu complex and site-specific production of hydroxyl radicals Fulltext Access 32 Pages 2017
4-hydroxynonenal causes impairment of human subcutaneous adipogenesis and induction of adipocyte insulin resistance Fulltext Access 32 Pages 2017
Hydrogen peroxide modifies both activity and isoforms of acetylcholinesterase in human neuroblastoma SH-SY5Y cells Fulltext Access 32 Pages 2017
Chronic hyper-leptinemia induces insulin signaling disruption in adipocytes: Implications of NOS2 Fulltext Access 32 Pages 2017
Selenoprotein T is required for pathogenic bacteria avoidance in Caenorhabditis elegans Fulltext Access 32 Pages 2017
Brd4 inhibition attenuates unilateral ureteral obstruction-induced fibrosis by blocking TGF-β-mediated Nox4 expression Fulltext Access 32 Pages 2017
Glucocorticoid-mediated activation of GSK3β promotes tau phosphorylation and impairs memory in type 2 diabetes Fulltext Access 32 Pages 2017
Temporal changes in glutathione biosynthesis during the lipopolysaccharide-induced inflammatory response of THP-1 macrophages Fulltext Access 32 Pages 2017
Nuclear factor-erythroid-2 related transcription factor-1 (Nrf1) is regulated by O-GlcNAc transferase Fulltext Access 32 Pages 2017
Isolation and identification of senescent renal tubular epithelial cells using immunomagnetic beads based on DcR2 Fulltext Access 32 Pages 2017
Involvement of progranulin in modulating neuroinflammatory responses but not neurogenesis in the hippocampus of aged mice Fulltext Access 32 Pages 2017
Identification of potential therapeutic compounds for Parkinson's disease using Drosophila and human cell models Fulltext Access 32 Pages 2017
PEG-functionalized zinc oxide nanoparticles induce apoptosis in breast cancer cells through reactive oxygen species-dependent impairment of DNA damage repair enzyme NEIL2 Fulltext Access 32 Pages 2017
PGC-1α in aging and lifelong exercise training-mediated regulation of UPR in mouse liver Fulltext Access 32 Pages 2017
Knee extensor power asymmetry is unrelated to functional mobility of older adults Fulltext Access 32 Pages 2017
Leukoencephalopathy, cerebral calcifications, and cysts: A clinical case involving a long-term follow-up and literature review Fulltext Access 32 Pages 2017
Long-term exposition to a high fat diet favors the appearance of β-amyloid depositions in the brain of C57BL/6J mice. A potential model of sporadic Alzheimer's disease Fulltext Access 32 Pages 2017
Increased cortical capillary transit time heterogeneity in Alzheimer's disease: a DSC-MRI perfusion study Fulltext Access 32 Pages 2017
Investigating the amyloid-beta enhancing effect of cGMP in neuro2a cells Fulltext Access 32 Pages 2017
Aging modifies the effect of GCH1 RS11158026 on DAT uptake and Parkinson's disease clinical severity Fulltext Access 32 Pages 2017
Genetic ataxia telangiectasia porcine model phenocopies the multisystemic features of the human disease Fulltext Access 32 Pages 2017
Malnutrition in postacute geriatric care: Basic ESPEN diagnosis and etiology based diagnoses analyzed by length of stay, in-hospital mortality, and functional rehabilitation indexes Fulltext Access 32 Pages 2017
A Drosophila model of GDAP1 function reveals the involvement of insulin signalling in the mitochondria-dependent neuromuscular degeneration Fulltext Access 32 Pages 2017
IL-21/anti-Tim1/CD40 ligand promotes B10 activity in vitro and alleviates bone loss in experimental periodontitis in vivo Fulltext Access 32 Pages 2017
APOE moderates compensatory recruitment of neuronal resources during working memory processing in healthy older adults Fulltext Access 32 Pages 2017
Assessment of histone tail modifications and transcriptional profiling during colon cancer progression reveals a global decrease in H3K4me3 activity Fulltext Access 32 Pages 2017
Spinal cord anteroposterior atrophy in HAM/TSP: Magnetic resonance imaging and neuropathological analyses Fulltext Access 32 Pages 2017
RhoA GTPase oxidation stimulates cell proliferation via nuclear factor-κB activation Fulltext Access 32 Pages 2017
MiR-485-5p modulates mitochondrial fission through targeting mitochondrial anchored protein ligase in cardiac hypertrophy Fulltext Access 33 Pages 2017
18F-fallypride PET-CT of dopamine D2/D3 receptors in patients with sporadic amyotrophic lateral sclerosis Fulltext Access 33 Pages 2017
Differential effects of blood insulin and HbA1c on cerebral amyloid burden and neurodegeneration in nondiabetic cognitively normal older adults Fulltext Access 33 Pages 2017
Hepatic mitochondrial bioenergetics in aged C57BL/6 mice exhibit delayed recovery from severe burn injury Fulltext Access 33 Pages 2017
Oxidative stress induces mitotic arrest by inhibiting Aurora A-involved mitotic spindle formation Fulltext Access 33 Pages 2017
Soluble CD14 inhibits contractile function and insulin action in primary adult rat cardiomyocytes Fulltext Access 33 Pages 2017
Targeting the TLR4 signaling pathway by polyphenols: A novel therapeutic strategy for neuroinflammation Fulltext Access 33 Pages 2017
From lymphopoiesis to plasma cells differentiation, the age-related modifications of B cell compartment are influenced by “inflamm-ageing” Fulltext Access 33 Pages 2017
IL-6 promotes M2 macrophage polarization by modulating purinergic signaling and regulates the lethal release of nitric oxide during Trypanosoma cruzi infection Fulltext Access 33 Pages 2017
Reelin protects from colon pathology by maintaining the intestinal barrier integrity and repressing tumorigenic genes Fulltext Access 33 Pages 2017
Insulin regulates titin pre-mRNA splicing through the PI3K-Akt-mTOR kinase axis in a RBM20-dependent manner Fulltext Access 33 Pages 2017
Abnormal trajectories in cerebellum and brainstem volumes in carriers of the fragile X premutation Fulltext Access 33 Pages 2017
Knockdown of sestrin2 increases pro-inflammatory reactions and ER stress in the endothelium via an AMPK dependent mechanism Fulltext Access 33 Pages 2017
The retromer complex system in a transgenic mouse model of AD: influence of age Fulltext Access 33 Pages 2017
Protective effect of resveratrol against inflammation, oxidative stress and apoptosis in pancreas of aged SAMP8 mice Fulltext Access 33 Pages 2017
Factors associated with fear of falling in community-dwelling older adults with and without diabetes mellitus: Findings from the Frailty in Brazilian Older People Study (FIBRA-BR) Fulltext Access 33 Pages 2017
Cerebrospinal fluid levels of orexin-A and histamine, and sleep profile within the Alzheimer process Fulltext Access 33 Pages 2017
GL-V9 induced upregulation and mitochondrial localization of NAG-1 associates with ROS generation and cell death in hepatocellular carcinoma cells Fulltext Access 33 Pages 2017
Tumor necrosis factor-alpha and soluble TNF-alpha receptor responses in young vs. middle-aged males following eccentric exercise Fulltext Access 34 Pages 2017
q-Space Myelin Map imaging for longitudinal analysis of demyelination and remyelination in multiple sclerosis patients treated with fingolimod: A preliminary study Fulltext Access 34 Pages 2017
Metabolomic analysis of oxidative stress: Superoxide dismutase mutation and paraquat induced stress in Drosophila melanogaster Fulltext Access 34 Pages 2017
Regulatory region genetic variation is associated with FYN expression in Alzheimer's disease Fulltext Access 34 Pages 2017
MDA-MB-231 breast cancer cells fuel osteoclast metabolism and activity: A new rationale for the pathogenesis of osteolytic bone metastases Fulltext Access 34 Pages 2017
Oculogyric crises: Etiology, pathophysiology and therapeutic approaches Fulltext Access 34 Pages 2017
Redox environment in stem and differentiated cells: A quantitative approach Fulltext Access 34 Pages 2017
Enforced DNA repair enzymes rescue neurons from apoptosis induced by target deprivation and axotomy in mouse models of neurodegeneration Fulltext Access 34 Pages 2017
AMPK orchestrates an elaborate cascade protecting tissue from fibrosis and aging Fulltext Access 34 Pages 2017
Exercise redox biochemistry: Conceptual, methodological and technical recommendations Fulltext Access 34 Pages 2017
A framework for identifying the adaptations responsible for differences in pegboard times between middle-aged and older adults Fulltext Access 34 Pages 2017
Euphorbia factor L1 inhibits osteoclastogenesis by regulating cellular redox status and induces Fas-mediated apoptosis in osteoclast Fulltext Access 34 Pages 2017
Rifampicin-induced injury in HepG2 cells is alleviated by TUDCA via increasing bile acid transporters expression and enhancing the Nrf2-mediated adaptive response Fulltext Access 34 Pages 2017
Aspirin prevents TNF-α-induced endothelial cell dysfunction by regulating the NF-κB-dependent miR-155/eNOS pathway: Role of a miR-155/eNOS axis in preeclampsia Fulltext Access 34 Pages 2017
The neuron-astrocyte-microglia triad in CA3 after chronic cerebral hypoperfusion in the rat: Protective effect of dipyridamole Fulltext Access 34 Pages 2017
Non-enzymatic oxidized metabolite of DHA, 4(RS)-4-F4t-neuroprostane protects the heart against reperfusion injury Fulltext Access 34 Pages 2017
Treadmill exercise alleviates motor deficits and improves mitochondrial import machinery in an MPTP-induced mouse model of Parkinson's disease Fulltext Access 34 Pages 2017
Aging and circadian dysfunction increase alcohol sensitivity and exacerbate mortality in Drosophila melanogaster Fulltext Access 34 Pages 2017
Copper therapy reduces intravascular hemolysis and derepresses ferroportin in mice with mosaic mutation (Atp7amo-ms): An implication for copper-mediated regulation of the Slc40a1 gene expression Fulltext Access 34 Pages 2017
Sodium butyrate exerts protective effect against Parkinson's disease in mice via stimulation of glucagon like peptide-1 Fulltext Access 34 Pages 2017
In-vivo reflectance confocal microscopy of Meissner's corpuscles in diabetic distal symmetric polyneuropathy Fulltext Access 34 Pages 2017
Global brain atrophy and metabolic dysfunction in LGI1 encephalitis: A prospective multimodal MRI study Fulltext Access 34 Pages 2017
Common PHOX2B poly-alanine contractions impair RET gene transcription, predisposing to Hirschsprung disease Fulltext Access 34 Pages 2017
Nitric oxide donor [Ru(terpy)(bdq)NO]3+ induces uncoupling and phosphorylation of endothelial nitric oxide synthase promoting oxidant production Fulltext Access 34 Pages 2017
Caloric restriction alleviates alpha-synuclein toxicity in aged yeast cells by controlling the opposite roles of Tor1 and Sir2 on autophagy Fulltext Access 34 Pages 2017
The role of the TOR pathway in mediating the link between nutrition and longevity Fulltext Access 35 Pages 2017
Development of a measure to evaluate gains among spanish dementia caregivers: The gains associated with caregiving (GAC) scale Fulltext Access 35 Pages 2017
IGF-II promotes neuroprotection and neuroplasticity recovery in a long-lasting model of oxidative damage induced by glucocorticoids Fulltext Access 35 Pages 2017
Epigenetic regulation of estrogen receptor α contributes to age-related differences in transcription across the hippocampal regions CA1 and CA3 Fulltext Access 35 Pages 2017
18F-FDG PET hypometabolism patterns reflect clinical heterogeneity in sporadic forms of early-onset Alzheimer's disease Fulltext Access 35 Pages 2017