• Daneshyari
  • Topics
    • Physical Sciences and Engineering
      Life Sciences
      Health Sciences
      Social Sciences and Humanities
Daneshyari Cell Biology Journas Latest Articles

Cell Biology Research Articles

Selective evolutionary pressure from the tissue microenvironment drives tumor progression
Fulltext Access 9 Pages 2005
PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteins
Fulltext Access 9 Pages 2005
Cathepsin B and tumor proteolysis: contribution of the tumor microenvironment
Fulltext Access 9 Pages 2005
Tissue homeostasis and the control of the neoplastic phenotype in epithelial cancers
Fulltext Access 9 Pages 2005
Pyruvate kinase type M2 and its role in tumor growth and spreading
Fulltext Access 9 Pages 2005
In vitro and in vivo imaging of cell migration: Two interdepending methods to unravel metastasis formation
Fulltext Access 9 Pages 2005
3D-extravasation model - selection of highly motile and metastatic cancer cells
Fulltext Access 9 Pages 2005
Matrigel: Basement membrane matrix with biological activity
Fulltext Access 9 Pages 2005
ETV6-NTRK3: a chimeric protein tyrosine kinase with transformation activity in multiple cell lineages
Fulltext Access 9 Pages 2005
Understanding mesenchymal cancer: the liposarcoma-associated FUS-DDIT3 fusion gene as a model
Fulltext Access 9 Pages 2005
The EWS-WT1 gene fusion in desmoplastic small round cell tumor
Fulltext Access 9 Pages 2005
Emergence and prevention of resistance against small molecule inhibitors
Fulltext Access 9 Pages 2005
Binding of JAB1/CSN5 to MIF is mediated by the MPN domain but is independent of the JAMM motif
Fulltext Access 9 Pages 2005
Budded karyoplasts from multinucleated fibroblast cells contain centrosomes and change their morphology to mitotic cells
Fulltext Access 9 Pages 2005
COMBO-FISH for focussed fluorescence labelling of gene domains: 3D-analysis of the genome architecture of abl and bcr in human blood cells
Fulltext Access 9 Pages 2005
Effect of oxidative stress on in vivo ADP-ribosylation of eukaryotic elongation factor 2
Fulltext Access 9 Pages 2005
BAG-1: a multi-functional pro-survival molecule
Fulltext Access 9 Pages 2005
Human peripheral blood eosinophils induce angiogenesis
Fulltext Access 9 Pages 2005
Dual-specificity tyrosine-phosphorylated and regulated kinase 1A (DYRK1A) interacts with the phytanoyl-CoA α-hydroxylase associated protein 1 (PAHX-AP1), a brain specific protein
Fulltext Access 9 Pages 2005
Molecular mechanisms of TNF-α-induced apoptosis in aging human T cell subsets
Fulltext Access 9 Pages 2005
A mouse model of Werner Syndrome: what can it tell us about aging and cancer?
Fulltext Access 9 Pages 2005
Chaperone-like activity of β-casein
Fulltext Access 9 Pages 2005
Carbohydrate-specifically polyethylene glycol-modified ricin A-chain with improved therapeutic potential
Fulltext Access 9 Pages 2005
Intracellular signal transduction pathways induced by leptin in C2C12 cells
Fulltext Access 9 Pages 2005
De-differentiation-derived mesenchymal stem cells demonstrate selective repression in H19 bioregulatory RNA gene expression
Fulltext Access 9 Pages 2005
Metaplasia in the pancreas
Fulltext Access 9 Pages 2005
Negative regulation of Gli1 and Gli2 activator function by Suppressor of fused through multiple mechanisms
Fulltext Access 9 Pages 2005
Developmental expression of two Haliotis asinina hemocyanin isoforms
Fulltext Access 9 Pages 2005
Expression of human TFF3 in relation to growth of HT-29 cell subpopulations: involvement of PI3-K but not STAT6
Fulltext Access 9 Pages 2005
Brown adipose tissue mitochondrial subpopulations show different morphological and thermogenic characteristics
Fulltext Access 9 Pages 2005
Centrosome aberrations in hematological malignancies
Fulltext Access 9 Pages 2005
Generation of embryoid bodies from mouse embryonic stem cells cultured on STO feeder cells
Fulltext Access 9 Pages 2005
Interleukin-15 stimulates adiponectin secretion by 3T3-L1 adipocytes: Evidence for a skeletal muscle-to-fat signaling pathway
Fulltext Access 9 Pages 2005
Influence of membrane physical state on lysosomal potassium ion permeability
Fulltext Access 9 Pages 2005
In vitro differentiation of human dental follicle cells with dexamethasone and insulin
Fulltext Access 9 Pages 2005
Photodynamic damages induced by a monocationic porphyrin derivative in a human carcinoma cell line
Fulltext Access 9 Pages 2005
Role of reactive oxygen species (ROS), metalloproteinase-2 (MMP-2) and interleukin-6 (IL-6) in direct interactions between tumour cell spheroids and endothelial cell monolayer
Fulltext Access 9 Pages 2005
Expression of silicatein in spicules from the Baikalian sponge Lubomirskia baicalensis
Fulltext Access 9 Pages 2005
In vivo expression and characteristics of novel α-d-mannose-rich glycoprotein markers of apoptotic cells
Fulltext Access 9 Pages 2005
Establishment and characterization of endothelial cell lines from the aorta of miniature pig for the study of xenotransplantation
Fulltext Access 9 Pages 2005
FMS*Calciumfluor specifically increases mRNA levels and induces signaling via MAPK 42,44 and not FAK in differentiating rat osteoblasts
Fulltext Access 9 Pages 2005
The plant P1B-type ATPase AtHMA4 transports Zn and Cd and plays a role in detoxification of transition metals supplied at elevated levels
Fulltext Access 9 Pages 2005
Comparison of the current RefSeq, Ensembl and EST databases for counting genes and gene discovery
Fulltext Access 9 Pages 2005
Cortactin phosphorylation as a switch for actin cytoskeletal network and cell dynamics control
Fulltext Access 9 Pages 2005
Expression profiling of the estrogen responsive genes in response to phytoestrogens using a customized DNA microarray
Fulltext Access 9 Pages 2005
Analysis of the mKir2.1 channel activity in potassium influx defective Saccharomyces cerevisiae strains determined as changes in growth characteristics
Fulltext Access 9 Pages 2005
Structural domains in RNAi
Fulltext Access 9 Pages 2005
A novel neurotrophic role of secretory phospholipases A2 for cerebellar granule neurons
Fulltext Access 9 Pages 2005
Evidence of differential pH regulation of the Arabidopsis vacuolar Ca2+/H+ antiporters CAX1 and CAX2
Fulltext Access 9 Pages 2005
Transgenic mice expressing mutant (N279K) human tau show mutation dependent cognitive deficits without neurofibrillary tangle formation
Fulltext Access 9 Pages 2005
Expression and functional characterization of LRRC4, a novel brain-specific member of the LRR superfamily
Fulltext Access 9 Pages 2005
TNF-α enhances phenotypic and functional maturation of human epidermal Langerhans cells and induces IL-12 p40 and IP-10/CXCL-10 production
Fulltext Access 9 Pages 2005
Comparison of replicative senescence and stress-induced premature senescence combining differential display and low-density DNA arrays
Fulltext Access 9 Pages 2005
Clp upregulates transcription of engA gene encoding a virulence factor in Xanthomonas campestris by direct binding to the upstream tandem Clp sites
Fulltext Access 9 Pages 2005
Inducible expression of a degradation-resistant form of p27Kip1 causes growth arrest and apoptosis in breast cancer cells
Fulltext Access 9 Pages 2005
The yeast osmosensitive mutant fps1Δ transformed by the cauliflower BobTIP1;1 aquaporin withstand a hypo-osmotic shock
Fulltext Access 9 Pages 2005
Antiviral silencing in animals
Fulltext Access 9 Pages 2005
microRNA biogenesis and function in plants
Fulltext Access 9 Pages 2005
Investigation of cell cycle arrest effects of actinomycin D at G1 phase using proteomic methods in B104-1-1 cells
Fulltext Access 9 Pages 2005
ET-18-O-CH3-induced apoptosis is causally linked to COX-2 upregulation in H-ras transformed human breast epithelial cells
Fulltext Access 9 Pages 2005
Sensitivity of the Drosophila para sodium channel to DDT is not lowered by the super-kdr mutation M918T on the IIS4–S5 linker that profoundly reduces sensitivity to permethrin and deltamethrin
Fulltext Access 9 Pages 2005
Immune cell-induced synthesis of NO and reactive oxygen species in lymphoma cells causes their death by apoptosis
Fulltext Access 9 Pages 2005
High resolution crystal structures of human Rab4a in its active and inactive conformations
Fulltext Access 9 Pages 2005
Modulating furin activity with designed mini-PDX peptides: Synthesis and in vitro kinetic evaluation
Fulltext Access 9 Pages 2005
GABA, progesterone and zona pellucida activation of PLA2 and regulation by MEK-ERK1/2 during acrosomal exocytosis in guinea pig spermatozoa
Fulltext Access 9 Pages 2005
Cell-cycle regulators are involved in transient cerebral ischemia induced neuronal apoptosis in female rats
Fulltext Access 9 Pages 2005
Oncostatin M induces proliferation of human adipose tissue-derived mesenchymal stem cells
Fulltext Access 9 Pages 2005
Ubiquitin-proteasome-dependent proteolytic activity remains elevated after zymosan-induced sepsis in rats while muscle mass recovers
Fulltext Access 9 Pages 2005
Cellular signals activating muscle proteolysis in chronic kidney disease: A two-stage process
Fulltext Access 9 Pages 2005
Spindle cells and their role in Kaposi's sarcoma
Fulltext Access 9 Pages 2005
Fyn binding protein, Fyb, interacts with mammalian actin binding protein, mAbp1
Fulltext Access 9 Pages 2005
Simulating redox coupled proton transfer in cytochrome c oxidase: Looking for the proton bottleneck
Fulltext Access 9 Pages 2005
Reactive oxygen species-linked regulation of the multidrug resistance transporter P-glycoprotein in Nox-1 overexpressing prostate tumor spheroids
Fulltext Access 9 Pages 2005
A unified framework for unraveling the functional interaction structure of a biomolecular network based on stimulus-response experimental data
Fulltext Access 9 Pages 2005
STAT4 is a target of the hematopoietic zinc-finger transcription factor Ikaros in T cells
Fulltext Access 9 Pages 2005
Mapping of C-termini of V-ATPase subunits by in vivo-FRET measurements
Fulltext Access 9 Pages 2005
Involvement of HP1α protein in irreversible transcriptional inactivation by antiestrogens in breast cancer cells
Fulltext Access 9 Pages 2005
Epstein-Barr virus encoded latent membrane protein 1 modulates nuclear translocation of telomerase reverse transcriptase protein by activating nuclear factor-κB p65 in human nasopharyngeal carcinoma cells
Fulltext Access 9 Pages 2005
RNA interference-mediated silencing of the syntaxin 5 gene induces Golgi fragmentation but capable of transporting vesicles
Fulltext Access 9 Pages 2005
Molecular characterization of the first satellite DNA with CENP-B and CDEIII motifs in the bat Pipistrellus kuhli
Fulltext Access 9 Pages 2005
The hydrophobic amino acid residues in the membrane-proximal C tail of the G protein-coupled vasopressin V2 receptor are necessary for transport-competent receptor folding
Fulltext Access 9 Pages 2005
SNX9 as an adaptor for linking synaptojanin-1 to the Cdc42 effector ACK1
Fulltext Access 9 Pages 2005
Molecular evolution and multilocus sequence typing of 145 strains of SARS-CoV
Fulltext Access 9 Pages 2005
The interplay between structure and function in intrinsically unstructured proteins
Fulltext Access 9 Pages 2005
Protein phosphatase 4 – from obscurity to vital functions
Fulltext Access 9 Pages 2005
Natural selection in neoplastic progression of Barrett's esophagus
Fulltext Access 10 Pages 2005
O-GlcNAc glycosylation: a signal for the nuclear transport of cytosolic proteins?
Fulltext Access 10 Pages 2005
Insulin-like growth factor-I inhibits dexamethasone-induced proteolysis in cultured L6 myotubes through PI3K/Akt/GSK-3β and PI3K/Akt/mTOR-dependent mechanisms
Fulltext Access 10 Pages 2005
Modulation of blood coagulation and fibrinolysis by polyamines in the presence of glycosaminoglycans
Fulltext Access 10 Pages 2005
Ubiquitin–protein ligases in muscle wasting
Fulltext Access 10 Pages 2005
Muscle wasting in cardiac cachexia
Fulltext Access 10 Pages 2005
Folding and stability of a coiled-coil investigated using chemical and physical denaturing agents: Comparative analysis of polymerized and non-polymerized forms of α-tropomyosin
Fulltext Access 10 Pages 2005
Pro-inflammatory effect of Arum maculatum lectin and role of resident cells
Fulltext Access 10 Pages 2005
Accumulation of ubiquitin-conjugated cytokeratin fragments in tumor cells
Fulltext Access 10 Pages 2005
Dynamics of colorectal cancer
Fulltext Access 10 Pages 2005
Plasma free amino acid profile in cancer patients
Fulltext Access 10 Pages 2005
The evolutionary origin of genetic instability in cancer development
Fulltext Access 10 Pages 2005
Mechanisms leading to chromosomal instability
Fulltext Access 10 Pages 2005
Multiple numerical chromosome aberrations in cancer: what are their causes and what are their consequences?
Fulltext Access 10 Pages 2005
Origins and selection of p53 mutations in lung carcinogenesis
Fulltext Access 10 Pages 2005
<< < 1035 1036 1037 1038 1039 > >>
Related Topics
Apoptosis Articles
29123 Papers
Development Articles
12883 Papers
Cytotoxicity Articles
9900 Papers
Signal transduction Articles
5230 Papers
Bacteria Articles
4979 Papers
Insulin resistance Articles
4830 Papers
Flow cytometry Articles
4594 Papers
Cell cycle Articles
4584 Papers
Macrophage Articles
4285 Papers
TNF-α Articles
4204 Papers
Reproduction Articles
4160 Papers
ATP Articles
4142 Papers
Hydroxyapatite Articles
4033 Papers
Innate immunity Articles
3893 Papers
tumor necrosis factor Articles
3693 Papers
Macrophages Articles
3689 Papers
Tissue engineering Articles
3603 Papers
Autophagy Articles
3586 Papers
endoplasmic reticulum Articles
3542 Papers
Vascular endothelial growth factor Articles
3428 Papers
MicroRNA Articles
3363 Papers
C-reactive protein Articles
3321 Papers
Microglia Articles
3245 Papers
Dendritic cells Articles
3148 Papers
Endothelial cells Articles
3043 Papers
Endothelium Articles
2946 Papers
Immunocytochemistry Articles
2877 Papers
Stem cells Articles
2803 Papers
DNA repair Articles
2780 Papers
Muscle Articles
2735 Papers
Bone mineral density Articles
2697 Papers
Cell culture Articles
2695 Papers
Fibrosis Articles
2647 Papers
Cryopreservation Articles
2621 Papers
Pathology Articles
2605 Papers
Cell death Articles
2572 Papers
Cytoskeleton Articles
2558 Papers
Brachytherapy Articles
2546 Papers
Squamous cell carcinoma Articles
2508 Papers
Lignin Articles
2361 Papers
Bioinformatics Articles
2344 Papers
Metabolomics Articles
2337 Papers
Phosphate Articles
2313 Papers
Liposome Articles
2305 Papers
NSCLC Articles
2240 Papers
Molecular modeling Articles
2239 Papers
Neurogenesis Articles
2160 Papers
Cell adhesion Articles
2130 Papers
Phagocytosis Articles
2107 Papers
Mesenchymal stem cells Articles
2068 Papers
P-glycoprotein Articles
2020 Papers
Epidermal growth factor receptor Articles
1993 Papers
T cells Articles
1934 Papers
bone marrow Articles
1894 Papers
Osteoblast Articles
1863 Papers
Zeta potential Articles
1841 Papers
Biopsy Articles
1841 Papers
Endocytosis Articles
1797 Papers
Growth factors Articles
1768 Papers
Endothelial cell Articles
1709 Papers
Adenosine Triphosphate Articles
1706 Papers
Dosimetry Articles
1706 Papers
Porous materials Articles
1692 Papers
mtDNA Articles
1622 Papers
Chromatin Articles
1608 Papers
Androgen Receptor Articles
1587 Papers
FRET Articles
1583 Papers
Necrosis Articles
1548 Papers
Chemotaxis Articles
1530 Papers
myeloperoxidase Articles
1528 Papers
Proteasome Articles
1509 Papers
Phospholipid Articles
1504 Papers
ER, endoplasmic reticulum Articles
1482 Papers
Sperm Articles
1480 Papers
Fluorescence spectroscopy Articles
1458 Papers
caspase Articles
1443 Papers
Gene delivery Articles
1389 Papers
Integrin Articles
1373 Papers
Calmodulin Articles
1354 Papers
mAb, Monoclonal antibody Articles
1314 Papers
ECM, extracellular matrix Articles
1312 Papers
Carcinogenesis Articles
1284 Papers
PAGE, polyacrylamide gel electrophoresis Articles
1248 Papers
FCS, fetal calf serum Articles
1227 Papers
Caspase-3 Articles
1224 Papers
T cell Articles
1197 Papers
Lectin Articles
1182 Papers
Fibroblast Articles
1175 Papers
Endothelial dysfunction Articles
1156 Papers
Regulatory T cells Articles
1152 Papers
ALP Articles
1145 Papers
Creatine kinase Articles
1141 Papers
Osteoblasts Articles
1132 Papers
NADPH oxidase Articles
1129 Papers
Hypertrophy Articles
1080 Papers
Sarcoma Articles
1065 Papers
Systems biology Articles
1062 Papers
semen Articles
1028 Papers
Cell wall Articles
1022 Papers
Plasmid Articles
1015 Papers
Microtubules Articles
991 Papers
IFN, interferon Articles
974 Papers
Antigen Articles
968 Papers
Mesenchymal stem cell Articles
967 Papers
Mast cell Articles
958 Papers
Hepatocyte Articles
952 Papers
Programmed cell death Articles
945 Papers
Mitosis Articles
938 Papers
Embryonic stem cells Articles
936 Papers
Trypsin Articles
929 Papers
Ferroelectric Articles
926 Papers
Monocyte Articles
914 Papers
ATPase Articles
912 Papers
CELLCYCLE Articles
908 Papers
triacylglycerol Articles
906 Papers
phosphatidylinositol Articles
898 Papers
Keratinocytes Articles
898 Papers
Lymph node Articles
894 Papers
Metabolic engineering Articles
892 Papers
Protein engineering Articles
881 Papers
Chondrocyte Articles
871 Papers
Endocrinology Articles
871 Papers
Failure analysis Articles
865 Papers
Leukocytes Articles
861 Papers
Cell therapy Articles
840 Papers
Protozoa Articles
825 Papers
Heat shock proteins Articles
822 Papers
Natural killer cells Articles
818 Papers
Cell differentiation Articles
811 Papers
Sarcoplasmic reticulum Articles
808 Papers
Cell viability Articles
803 Papers
Calpain Articles
800 Papers
LDH, lactate dehydrogenase Articles
798 Papers
Ion channels Articles
794 Papers
ATP, adenosine triphosphate Articles
792 Papers
Telomere Articles
783 Papers
Erythrocytes Articles
778 Papers
Osmoregulation Articles
775 Papers
Adipocyte Articles
772 Papers
Myelin Articles
769 Papers
Integrins Articles
766 Papers
Hemolysis Articles
761 Papers
Adipogenesis Articles
755 Papers
sphingomyelin Articles
746 Papers
Hydrophilicity Articles
740 Papers
Cancer stem cells Articles
726 Papers
Insulin sensitivity Articles
723 Papers
cytology Articles
723 Papers
Chondrocytes Articles
723 Papers
Unfolded protein response Articles
696 Papers
Neural stem cells Articles
687 Papers
Meiosis Articles
677 Papers
Small cell lung cancer Articles
677 Papers
Hydrophobic Articles
676 Papers
CP, crude protein Articles
674 Papers
Endoplasmic reticulum stress Articles
673 Papers
Enzyme inhibition Articles
667 Papers
epithelial cells Articles
661 Papers
Cell growth Articles
655 Papers
Cell cycle arrest Articles
652 Papers
Chloroplast Articles
649 Papers
Liver cancer Articles
618 Papers
Oligodendrocyte Articles
601 Papers
osteonecrosis Articles
601 Papers
Stem cell transplantation Articles
597 Papers
Exosomes Articles
588 Papers
Osteocalcin Articles
582 Papers
melanin Articles
574 Papers
Hyponatremia Articles
569 Papers
Synthetic biology Articles
556 Papers
MMP, matrix metalloproteinase Articles
552 Papers
Embryonic development Articles
541 Papers
Cord blood Articles
538 Papers
Western blotting Articles
532 Papers
Endothelial progenitor cells Articles
528 Papers
Cytotoxic Articles
521 Papers
Bone metastases Articles
507 Papers
Ageing Articles
Biochemistry Articles
Biochemistry, Genetics and Molecular Biology (General) Articles
Biophysics Articles
Biotechnology Articles
Cancer Research Articles
Cell Biology Articles
Clinical Biochemistry Articles
Developmental Biology Articles
Endocrinology Articles
Genetics Articles
Molecular Biology Articles
Molecular Medicine Articles
Physiology Articles
Structural Biology Articles
All Topics
Related Journals
Ageing Journals
Biochemistry Journals
Biochemistry, Genetics and Molecular Biology (General) Journals
Biophysics Journals
Biotechnology Journals
Cancer Research Journals
Cell Biology Journals
Clinical Biochemistry Journals
Developmental Biology Journals
Endocrinology Journals
Genetics Journals
Molecular Biology Journals
Molecular Medicine Journals
Physiology Journals
Structural Biology Journals
Biomaterials Journal
Chemistry and Physics of Lipids Journal
Micron Journal
Mechanisms of Ageing and Development Journal
Redox Biology Journal
Acta Histochemica Journal
Biochimica et Biophysica Acta (BBA) - Biomembranes Journal
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids Journal
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research Journal
Biochimie Open Journal
Cellular Signalling Journal
FEBS Open Bio Journal
The International Journal of Biochemistry & Cell Biology Journal
Molecular Cell Journal
Pharmacological Reports Journal
Progress in Histochemistry and Cytochemistry Journal
Progress in Lipid Research Journal
Regenerative Therapy Journal
Seminars in Cancer Biology Journal
Cell Journal
FEBS Letters Journal
Reproductive Biology Journal
Cell Biology International Journal
Mitochondrion Journal
Cell Stem Cell Journal
Journal of Applied Biomedicine Journal
Stem Cell Reports Journal
Stem Cell Research Journal
Biochimica et Biophysica Acta (BBA) - Reviews on Cancer Journal
Biology of Blood and Marrow Transplantation Journal
Cancer Cell Journal
Differentiation Journal
Experimental Cell Research Journal
Experimental Hematology Journal
Hematology/Oncology and Stem Cell Therapy Journal
Matrix Biology Journal
Cell Calcium Journal
Cellular Immunology Journal
Cryobiology Journal
Current Opinion in Cell Biology Journal
Cytokine & Growth Factor Reviews Journal
Cytotherapy Journal
Developmental Biology Journal
Developmental Cell Journal
Egyptian Journal of Medical Human Genetics Journal
European Journal of Cell Biology Journal
Flora - Morphology, Distribution, Functional Ecology of Plants Journal
Fungal Biology Reviews Journal
Fungal Genetics and Biology Journal
Gene Expression Patterns Journal
Genes & Diseases Journal
Immunobiology Journal
Journal of Molecular Biology Journal
Journal of Molecular and Cellular Cardiology Journal
Mammalian Biology - Zeitschrift für Säugetierkunde Journal
Mechanisms of Development Journal
Molecular and Cellular Endocrinology Journal
Molecular and Cellular Neuroscience Journal
Molecular and Cellular Probes Journal
Neurochemistry International Journal
Results in Immunology Journal
Seminars in Cell & Developmental Biology Journal
Tissue and Cell Journal
Trends in Cell Biology Journal
Virology Reports Journal

Daneshyari.com

دسترسی سریع

  • صفحه اصلی دانشیاری
  • دسته بندی موضوعی مقالات
  • مقالات ترجمه شده
  • سفارش ترجمه مقاله
  • سفارش تولید محتوا
  • تولید محتوا

ارتباط

  • ورود
  • عضویت
  • تماس و پشتیبانی
  • تبلیغات

English Website

  • Home
  • Physical Sciences and Engineering
  • Life Sciences
  • Health Sciences
  • Social Sciences and Humanities