γ-Taxilin temporally regulates centrosome disjunction in a Nek2A-dependent manner Fulltext Access 12 Pages 2018
Up-regulated miR-548k promotes esophageal squamous cell carcinoma progression via targeting long noncoding RNA-LET Fulltext Access 12 Pages 2018
ADAMTS-1 disrupts HGF/c-MET signaling and HGF-stimulated cellular processes in fibrosarcoma Fulltext Access 12 Pages 2018
Multi-tasking Sulf1/Sulf2 enzymes do not only facilitate extracellular cell signalling but also participate in cell cycle related nuclear events Fulltext Access 12 Pages 2018
Arginine inhibits the malignant transformation induced by interferon-gamma through the NF-κB-GCN2/eIF2α signaling pathway in mammary epithelial cells in vitro and in vivo Fulltext Access 12 Pages 2018
Silencing PFKP inhibits starvation-induced autophagy, glycolysis, and epithelial mesenchymal transition in oral squamous cell carcinoma Fulltext Access 12 Pages 2018
A Vascular Endothelial Growth Factor-Dependent Sprouting Angiogenesis Assay Based on an In Vitro Human Blood Vessel Model for the Study of Anti-Angiogenic Drugs Fulltext Access 12 Pages 2018
Ancestral Variations of the PCDHG Gene Cluster Predispose to Dyslexia in a Multiplex Family Fulltext Access 12 Pages 2018
GABA Regulates Release of Inflammatory Cytokines From Peripheral Blood Mononuclear Cells and CD4+ T Cells and Is Immunosuppressive in Type 1 Diabetes Fulltext Access 12 Pages 2018
Inhibition of the mitochondrial calcium uniporter prevents IL-13 and allergen-mediated airway epithelial apoptosis and loss of barrier function Fulltext Access 12 Pages 2018
IL-4 Receptor Alpha Signaling through Macrophages Differentially Regulates Liver Fibrosis Progression and Reversal Fulltext Access 12 Pages 2018
Identification of Serine 119 as an Effective Inhibitor Binding Site of M. tuberculosis Ubiquitin-like Protein Ligase PafA Using Purified Proteins and M. smegmatis Fulltext Access 12 Pages 2018
Hydroxylase Activity of ASPH Promotes Hepatocellular Carcinoma Metastasis Through Epithelial-to-Mesenchymal Transition Pathway Fulltext Access 12 Pages 2018
The Novel Pathogenesis of Retinopathy Mediated by Multiple RTK Signals is Uncovered in Newly Developed Mouse Model Fulltext Access 12 Pages 2018
MARCKSL1 Regulates Spine Formation in the Amygdala and Controls the Hypothalamic-Pituitary-Adrenal Axis and Anxiety-Like Behaviors Fulltext Access 12 Pages 2018
Integrative (epi) Genomic Analysis to Predict Response to Androgen-Deprivation Therapy in Prostate Cancer Fulltext Access 12 Pages 2018
A Genomic-clinicopathologic Nomogram for the Preoperative Prediction of Lymph Node Metastasis in Bladder Cancer Fulltext Access 12 Pages 2018
Oxysterol Signatures Distinguish Age-Related Macular Degeneration from Physiologic Aging Fulltext Access 12 Pages 2018
Extracellular Vesicles Secreted by Human Adipose-derived Stem Cells (hASCs) Improve Survival Rate of Rats with Acute Liver Failure by Releasing lncRNA H19 Fulltext Access 12 Pages 2018
HDAC inhibitor suppresses proliferation and tumorigenicity of drug-resistant chronic myeloid leukemia stem cells through regulation of hsa-miR-196a targeting BCR/ABL1 Fulltext Access 12 Pages 2018
The Autism-Related Protein PX-RICS Mediates GABAergic Synaptic Plasticity in Hippocampal Neurons and Emotional Learning in Mice Fulltext Access 12 Pages 2018
BC200 (BCYRN1) - The shortest, long, non-coding RNA associated with cancer Fulltext Access 13 Pages 2018
Effects of manganese toxicity on the protein profile of tomato (Solanum lycopersicum) roots as revealed by two complementary proteomic approaches, two-dimensional electrophoresis and shotgun analysis Fulltext Access 13 Pages 2018
Intracerebroventricular injection of Aβ1-42 combined with two-vessel occlusion accelerate Alzheimer's disease development in rats Fulltext Access 13 Pages 2018
Sphingosine kinase 2 cooperating with Fyn promotes kidney fibroblast activation and fibrosis via STAT3 and AKT Fulltext Access 13 Pages 2018
Crosstalk between Na+,K+-ATPase and a volume-regulated anion channel in membrane microdomains of human cancer cells Fulltext Access 13 Pages 2018
Small GTPases SAR1A and SAR1B regulate the trafficking of the cardiac sodium channel Nav1.5 Fulltext Access 13 Pages 2018
Prostaglandin D2 Receptor DP1 Antibodies Predict Vaccine-induced and Spontaneous Narcolepsy Type 1: Large-scale Study of Antibody Profiling Fulltext Access 13 Pages 2018
Induction of the Immunoproteasome Subunit Lmp7 Links Proteostasis and Immunity in α-Synuclein Aggregation Disorders Fulltext Access 13 Pages 2018
CXCR3 expression in colorectal cancer cells enhanced invasion through preventing CXCR4 internalization Fulltext Access 13 Pages 2018
Long Non-Coding RNAs Associated with Metabolic Traits in Human White Adipose Tissue Fulltext Access 13 Pages 2018
Quercetin Reduces Cortical GABAergic Transmission and Alleviates MK-801-Induced Hyperactivity Fulltext Access 13 Pages 2018
T Cells Primed by Live Mycobacteria Versus a Tuberculosis Subunit Vaccine Exhibit Distinct Functional Properties Fulltext Access 13 Pages 2018
Bioprosthesis leaflet thrombosis following self-expanding valve-in-valve transcatheter aortic valve replacement in patient taking factor Xa inhibitor and warfarin: A case report Fulltext Access 13 Pages 2018
Mice with an Oncogenic HRAS Mutation are Resistant to High-Fat Diet-Induced Obesity and Exhibit Impaired Hepatic Energy Homeostasis Fulltext Access 13 Pages 2018
Assessment of ATP8B1 Deficiency in Pediatric Patients With Cholestasis Using Peripheral Blood Monocyte-Derived Macrophages Fulltext Access 13 Pages 2018
Zinc Deficiency via a Splice Switch in Zinc Importer ZIP2/SLC39A2 Causes Cystic Fibrosis-Associated MUC5AC Hypersecretion in Airway Epithelial Cells Fulltext Access 13 Pages 2018
Myosin phosphatase accelerates cutaneous wound healing by regulating migration and differentiation of epidermal keratinocytes via Akt signaling pathway in human and murine skin Fulltext Access 13 Pages 2018
Probing the colorectal cancer proteome for biomarkers: Current status and perspectives Fulltext Access 13 Pages 2018
A large-scale and robust dynamic MRM study of colorectal cancer biomarkers Fulltext Access 13 Pages 2018
Effect of N-acyl-dopamines on beta cell differentiation and wound healing in diabetic mice Fulltext Access 13 Pages 2018
Pyrrolidine nucleoside bisphosphonates as antituberculosis agents targeting hypoxanthine-guanine phosphoribosyltransferase Fulltext Access 13 Pages 2018
Identification of a splice variant of optineurin which is defective in autophagy and phosphorylation Fulltext Access 13 Pages 2018
Embryonic lethality in mice due to carnitine transporter OCTN2 defect and placental carnitine deficiency Fulltext Access 13 Pages 2018
Abnormal RNA splicing and genomic instability after induction of DNMT3A mutations by CRISPR/Cas9 gene editing Fulltext Access 13 Pages 2018
Synthesis, cytotoxicity and structure-activity relationship of indolizinoquinolinedione derivatives as DNA topoisomerase IB catalytic inhibitors Fulltext Access 13 Pages 2018
The lead optimization of the polyamine conjugate of flavonoid with a naphthalene motif: Synthesis and biological evaluation Fulltext Access 13 Pages 2018
Short-Term Hypoxia Dampens Inflammation in vivo via Enhanced Adenosine Release and Adenosine 2B Receptor Stimulation Fulltext Access 13 Pages 2018
Design, semisynthesis, α-glucosidase inhibitory, cytotoxic, and antibacterial activities of p-terphenyl derivatives Fulltext Access 13 Pages 2018
Substituted tetrahydroisoquinolines: synthesis, characterization, antitumor activity and other biological properties Fulltext Access 13 Pages 2018
Synthesis and structure-activity relationships of asymmetric dimeric β-carboline derivatives as potential antitumor agents Fulltext Access 13 Pages 2018
Recent progress in potential anti-hepatitis B virus agents: Structural and pharmacological perspectives Fulltext Access 13 Pages 2018
Synthesis of 3â²-halo-5â²-norcarbocyclic nucleoside phosphonates as potent anti-HIV agents Fulltext Access 13 Pages 2018
The aminopyridine-3,5-dicarbonitrile core for the design of new non-nucleoside-like agonists of the human adenosine A2B receptor Fulltext Access 13 Pages 2018
2-Benzylpiperazine: A new scaffold for potent human carbonic anhydrase inhibitors. Synthesis, enzyme inhibition, enantioselectivity, computational and crystallographic studies and in vivo activity for a new class of intraocular pressure lowering agents Fulltext Access 13 Pages 2018
Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents Fulltext Access 13 Pages 2018
Recent advances in trimethoxyphenyl (TMP) based tubulin inhibitors targeting the colchicine binding site Fulltext Access 13 Pages 2018
Design, synthesis and biological evaluation of non-secosteriodal vitamin D receptor ligand bearing double side chain for the treatment of chronic pancreatitis Fulltext Access 13 Pages 2018
Design, synthesis and biological evaluation of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido)benzoyl hydrazide derivatives as thymidylate synthase (TS) inhibitors and as potential antitumor drugs Fulltext Access 13 Pages 2018
Two new Cu(II) dipeptide complexes based on 5-methyl-2-(2â²-pyridyl)benzimidazole as potential antimicrobial and anticancer drugs: Special exploration of their possible anticancer mechanism Fulltext Access 13 Pages 2018
Novel ruthenium(II) triazine complex [Ru(bdpta)(tpy)]2+ co-targeting drug resistant GRP78 and subcellular organelles in cancer stem cells Fulltext Access 13 Pages 2018
Integrated physiological and proteomic analysis reveals underlying response and defense mechanisms of Brachypodium distachyon seedling leaves under osmotic stress, cadmium and their combined stresses Fulltext Access 13 Pages 2018
PPARγ agonist rosiglitazone switches fuel preference to lipids in promoting thermogenesis under cold exposure in C57BL/6 mice Fulltext Access 13 Pages 2018
Variety-specific nutrient acquisition and dehydration-induced proteomic landscape of grasspea (Lathyrus sativus L.) Fulltext Access 13 Pages 2018
Proteomics, functional characterization and antivenom neutralization of the venom of Pakistani Russell's viper (Daboia russelii) from the wild Fulltext Access 13 Pages 2018
Exosomes derived from calcium oxalate-exposed macrophages enhance IL-8 production from renal cells, neutrophil migration and crystal invasion through extracellular matrix Fulltext Access 13 Pages 2018
Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress Fulltext Access 13 Pages 2018
The role of gastrulation brain homeobox 2 (gbx2) in the development of the ventral telencephalon in zebrafish embryos Fulltext Access 13 Pages 2018
Presenilin gene function and Notch signaling feedback regulation in the developing mouse lens Fulltext Access 13 Pages 2018
Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies? Fulltext Access 13 Pages 2018
Daily therapy with a slow-releasing H2S donor GYY4137 enables early functional recovery and ameliorates renal injury associated with urinary obstruction Fulltext Access 13 Pages 2018
Absorption, metabolism, distribution and excretion of (â)-epicatechin: A review of recent findings Fulltext Access 13 Pages 2018
Distorted leukocyte migration, angiogenesis, wound repair and metastasis in Tspan8 and Tspan8/CD151 double knockout mice indicate complementary activities of Tspan8 and CD51 Fulltext Access 13 Pages 2018
In vitro identification of mitochondrial oxidative stress production by time-resolved fluorescence imaging of glioma cells Fulltext Access 13 Pages 2018
The nonreceptor tyrosine kinase c-Abl phosphorylates Runx1 and regulates Runx1-mediated megakaryocyte maturation Fulltext Access 13 Pages 2018
Resolvin D1 blocks H2O2-mediated inhibitory crosstalk between SHP2 and PP2A and suppresses endothelial-monocyte interactions Fulltext Access 13 Pages 2018
Histone variant H2A.Z antagonizes the positive effect of the transcriptional activator CPC1 to regulate catalase-3 expression under normal and oxidative stress conditions Fulltext Access 13 Pages 2018
Oleanolic acid attenuates PCBs-induced adiposity and insulin resistance via HNF1b-mediated regulation of redox and PPARγ signaling Fulltext Access 13 Pages 2018
Inferring anatomical therapeutic chemical (ATC) class of drugs using shortest path and random walk with restart algorithms Fulltext Access 13 Pages 2018
Natural product inspired library synthesis - Identification of 2,3-diarylbenzofuran and 2,3-dihydrobenzofuran based inhibitors of Chlamydia trachomatis Fulltext Access 13 Pages 2018
Synthesis and biological evaluation of N-substituted 3-oxo-1,2,3,4-tetrahydro-quinoxaline-6-carboxylic acid derivatives as tubulin polymerization inhibitors Fulltext Access 13 Pages 2018
Antagonists of the adenosine A2A receptor based on a 2-arylbenzoxazole scaffold: Investigation of the C5- and C7-positions to enhance affinity Fulltext Access 13 Pages 2018
Design, synthesis and biological evaluation of LX2343 derivatives as neuroprotective agents for the treatment of Alzheimer's disease Fulltext Access 13 Pages 2018
Increased mitochondrial DNA copy number in maternal peripheral blood is associated with low birth weight in Lombok, Indonesia Fulltext Access 14 Pages 2018
In vitro analysis of the transcriptional regulatory mechanism of zebrafish pou5f3 Fulltext Access 14 Pages 2018
A web platform for the network analysis of high-throughput data in melanoma and its use to investigate mechanisms of resistance to anti-PD1 immunotherapy Fulltext Access 14 Pages 2018
Acidic pHe regulates cytoskeletal dynamics through conformational integrin β1 activation and promotes membrane protrusion Fulltext Access 14 Pages 2018
Pt(IV) prodrugs containing microtubule inhibitors displayed potent antitumor activity and ability to overcome cisplatin resistance Fulltext Access 14 Pages 2018
6-Arylthio-3-hydroxypyrimidine-2,4-diones potently inhibited HIV reverse transcriptase-associated RNase H with antiviral activity Fulltext Access 14 Pages 2018
Novel indolo-sophoridinic scaffold as Topo I inhibitors: Design, synthesis and biological evaluation as anticancer agents Fulltext Access 14 Pages 2018
Optimization of the first small-molecule relaxin/insulin-like family peptide receptor (RXFP1) agonists: Activation results in an antifibrotic gene expression profile Fulltext Access 14 Pages 2018
Inactivation of glycogen synthase kinase 3β (GSK-3β) enhances mitochondrial biogenesis during myogenesis Fulltext Access 14 Pages 2018
hnRNP A1 promotes keratinocyte cell survival post UVB radiation through PI3K/Akt/mTOR pathway Fulltext Access 14 Pages 2018