RankProd Combined with Genetic Algorithm Optimized Artificial Neural Network Establishes a Diagnostic and Prognostic Prediction Model that Revealed C1QTNF3 as a Biomarker for Prostate Cancer Fulltext Access 11 Pages 2018
HIV Activates the Tyrosine Kinase Hck to Secrete ADAM Protease-Containing Extracellular Vesicles Fulltext Access 11 Pages 2018
Transcriptomics and Targeted Proteomics Analysis to Gain Insights Into the Immune-control Mechanisms of HIV-1 Infected Elite Controllers Fulltext Access 11 Pages 2018
Losmapimod Overcomes Gefitinib Resistance in Non-small Cell Lung Cancer by Preventing Tetraploidization Fulltext Access 11 Pages 2018
Vinorelbine Potently Induces Placental Cell Death, Does Not Harm Fertility and is a Potential Treatment for Ectopic Pregnancy Fulltext Access 11 Pages 2018
Fecal Microbiota Composition Drives Immune Activation in HIV-infected Individuals Fulltext Access 11 Pages 2018
Inhibition of HDACs-EphA2 Signaling Axis with WW437 Demonstrates Promising Preclinical Antitumor Activity in Breast Cancer Fulltext Access 11 Pages 2018
Oligodendrocyte Progenitor Cells and Macrophages/Microglia Produce Glioma Stem Cell Niches at the Tumor Border Fulltext Access 11 Pages 2018
A Validated Clinical Risk Prediction Model for Lung Cancer in Smokers of All Ages and Exposure Types: A HUNT Study Fulltext Access 11 Pages 2018
LDL Receptor Gene-ablated Hamsters: A Rodent Model of Familial Hypercholesterolemia With Dominant Inheritance and Diet-induced Coronary Atherosclerosis Fulltext Access 11 Pages 2018
Gefitinib for Epidermal Growth Factor Receptor Activated Osteoarthritis Subpopulation Treatment Fulltext Access 11 Pages 2018
TGF-β3 Promotes MUC5AC Hyper-Expression by Modulating Autophagy Pathway in Airway Epithelium Fulltext Access 11 Pages 2018
Immune Characteristics of Chinese Diffuse Large B-Cell Lymphoma Patients: Implications for Cancer Immunotherapies Fulltext Access 11 Pages 2018
Lnc-PCDH9-13:1 Is a Hypersensitive and Specific Biomarker for Early Hepatocellular Carcinoma Fulltext Access 11 Pages 2018
Proapoptotic Cyclic Peptide BC71 Targets Cell-Surface GRP78 and Functions as an Anticancer Therapeutic in Mice Fulltext Access 11 Pages 2018
Computational prediction of vaccine potential epitopes and 3-dimensional structure of XAGE-1b for non-small cell lung cancer immunotherapy Fulltext Access 11 Pages 2018
Genetic host factors in Helicobacter pylori-induced carcinogenesis: Emerging new paradigms Fulltext Access 11 Pages 2018
Modulations of Keap1-Nrf2 signaling axis by TIIA ameliorated the oxidative stress-induced myocardial apoptosis Fulltext Access 11 Pages 2018
Caspase-mediated cleavage of X-ray repair cross-complementing group 4 promotes apoptosis by enhancing nuclear translocation of caspase-activated DNase Fulltext Access 11 Pages 2018
Cmk2 kinase is essential for survival in arsenite by modulating translation together with RACK1 orthologue Cpc2 in Schizosaccharomyces pombe Fulltext Access 11 Pages 2018
Ubiquitination and SUMOylation in the chronic inflammatory tumor microenvironment Fulltext Access 11 Pages 2018
Effects of ionizing radiation and HPSE1 inhibition on the invasion of oral tongue carcinoma cells on human extracellular matrices in vitro Fulltext Access 11 Pages 2018
Osteoglycin-induced VEGF Inhibition Enhances T Lymphocytes Infiltrating in Colorectal Cancer Fulltext Access 11 Pages 2018
Proteomic profile, biological activities and antigenic analysis of the venom from Bothriopsis bilineata smaragdina (“loro machaco”), a pitviper snake from Peru Fulltext Access 11 Pages 2018
Proteomic study of endothelial dysfunction induced by AGEs and its possible role in diabetic cardiovascular complications Fulltext Access 11 Pages 2018
Enterococcus faecium produces membrane vesicles containing virulence factors and antimicrobial resistance related proteins Fulltext Access 11 Pages 2018
Microcalcifications in breast cancer: From pathophysiology to diagnosis and prognosis Fulltext Access 11 Pages 2018
Tsc1-dependent transcriptional programming of dendritic cell homeostasis and function Fulltext Access 11 Pages 2018
Bioactivity and gene expression profiles of hiPSC-generated retinal ganglion cells in MT-ND4 mutated Leber's hereditary optic neuropathy Fulltext Access 11 Pages 2018
microRNA-181a downregulates deptor for TGFβ-induced glomerular mesangial cell hypertrophy and matrix protein expression Fulltext Access 11 Pages 2018
Knockdown of MALAT1 enhances chemosensitivity of ovarian cancer cells to cisplatin through inhibiting the Notch1 signaling pathway Fulltext Access 11 Pages 2018
Spatial and temporal translocation of PKCα in single endothelial cell in response to mechanical stimulus Fulltext Access 11 Pages 2018
Langerhans Cells Prevent Autoimmunity via Expansion of Keratinocyte Antigen-Specific Regulatory T Cells Fulltext Access 11 Pages 2018
Glucocorticoids Regulate the Vascular Remodeling of Aortic Dissection Via the p38 MAPK-HSP27 Pathway Mediated by Soluble TNF-RII Fulltext Access 11 Pages 2018
RNA interference-mediated knockdown of SIRT1 and/or SIRT2 in melanoma: Identification of downstream targets by large-scale proteomics analysis Fulltext Access 11 Pages 2018
Comprehensive proteomic profiles of mouse AApoAII amyloid fibrils provide insights into the involvement of lipoproteins in the pathology of amyloidosis Fulltext Access 11 Pages 2018
Circadian control of p75 neurotrophin receptor leads to alternate activation of Nrf2 and c-Rel to reset energy metabolism in astrocytes via brain-derived neurotrophic factor Fulltext Access 11 Pages 2018
Combined transcriptomic/proteomic analysis of salivary gland and secreted saliva in three planthopper species Fulltext Access 11 Pages 2018
Proteomic analysis of Bombyx mori molting fluid: Insights into the molting process Fulltext Access 11 Pages 2018
Neurotoxicity of cytarabine (Ara-C) in dorsal root ganglion neurons originates from impediment of mtDNA synthesis and compromise of mitochondrial function Fulltext Access 11 Pages 2018
Pyridine nucleotides regulate the superoxide anion flash upon permeabilization of mitochondrial membranes: An MCLA-based study Fulltext Access 11 Pages 2018
A Photo-triggered and photo-calibrated nitric oxide donor: Rational design, spectral characterizations, and biological applications Fulltext Access 11 Pages 2018
Therapeutic potential of bixin in PM2.5 particles-induced lung injury in an Nrf2-dependent manner Fulltext Access 11 Pages 2018
Characterization of covalent modifications of HDL apoproteins by endogenous oxidized phospholipids Fulltext Access 11 Pages 2018
Malonylome analysis in developing rice (Oryza sativa) seeds suggesting that protein lysine malonylation is well-conserved and overlaps with acetylation and succinylation substantially Fulltext Access 11 Pages 2018
Mitochondrial protein S-nitrosation protects against ischemia reperfusion-induced denervation at neuromuscular junction in skeletal muscle Fulltext Access 11 Pages 2018
Crosstalk mechanisms between the WNT signaling pathway and long non-coding RNAs Fulltext Access 12 Pages 2018
Cardiogenic Shock Complicating Transcatheter Aortic Valve Replacement Due to Severe Para-Valvular Regurgitation Fulltext Access 12 Pages 2018
Assessment of leukocyte activity in mice devoid of the glucocorticoid receptor in the noradrenergic system (GRDBHCre) Fulltext Access 12 Pages 2018
Role of miR-1 expression in clear cell renal cell carcinoma (ccRCC): A bioinformatics study based on GEO, ArrayExpress microarrays and TCGA database Fulltext Access 12 Pages 2018
Pseudoaneurysm of the ascending thoracic aorta years after aortic valve replacement Fulltext Access 12 Pages 2018
Reductive chemical release of N-glycans as 1-amino-alditols and subsequent 9-fluorenylmethyloxycarbonyl labeling for MS and LC/MS analysis Fulltext Access 12 Pages 2018
Design, synthesis and biological evaluation of water-soluble per-O-methylated cyclodextrin-C60 conjugates as anti-influenza virus agents Fulltext Access 12 Pages 2018
Combined proteomic and functional analysis reveals rich sources of protein diversity in skin mucus and venom from the Scorpaena plumieri fish Fulltext Access 12 Pages 2018
Chemical chaperone 4-phenylbutyric acid alleviates the aggregation of human familial pulmonary fibrosis-related mutant SP-A2 protein in part through effects on GRP78 Fulltext Access 12 Pages 2018
CD51 is an independent unfavorable prognostic factor in esophageal squamous cell carcinoma Fulltext Access 12 Pages 2018
Study of a novel agent for TCA precipitated proteins washing - comprehensive insights into the role of ethanol/HCl on molten globule state by multi-spectroscopic analyses Fulltext Access 12 Pages 2018
Patient Derived Xenografts (PDX) for personalized treatment of pancreatic cancer: emerging allies in the war on a devastating cancer? Fulltext Access 12 Pages 2018
Phosphoproteomics unveils stable energy supply as key to flooding tolerance in Kandelia candel Fulltext Access 12 Pages 2018
Integrative transcriptome and proteome analyses define marked differences between Neospora caninum isolates throughout the tachyzoite lytic cycle Fulltext Access 12 Pages 2018
cPLA2 and desaturases underlie the tau hyperphosphorylation offset induced by BACE knock-down in neuronal primary cultures Fulltext Access 12 Pages 2018
ZIP9 but not the androgen receptor mediates testosterone-induced migratory activity of metastatic prostate cancer cells Fulltext Access 12 Pages 2018
Conjugation of a 5-nitrofuran-2-oyl moiety to aminoalkylimidazoles produces non-toxic nitrofurans that are efficacious in vitro and in vivo against multidrug-resistant Mycobacterium tuberculosis Fulltext Access 12 Pages 2018
Quantitative proteomics identify an association between extracellular matrix degradation and immunopathology of genotype VII Newcastle disease virus in the spleen in chickens Fulltext Access 12 Pages 2018
MitoQ improves mitochondrial dysfunction in heart failure induced by pressure overload Fulltext Access 12 Pages 2018
Crosstalk between autophagy and oxidative stress regulates proteolysis in the diaphragm during mechanical ventilation Fulltext Access 12 Pages 2018
Modulation of reactive oxygen species via ERK and STAT3 dependent signalling are involved in the response of mesothelioma cells to exemestane Fulltext Access 12 Pages 2018
SRSF5 functions as a novel oncogenic splicing factor and is upregulated by oncogene SRSF3 in oral squamous cell carcinoma Fulltext Access 12 Pages 2018
Decrease in paracellular permeability and chemosensitivity to doxorubicin by claudin-1 in spheroid culture models of human lung adenocarcinoma A549 cells Fulltext Access 12 Pages 2018
Ras-Raf-MAPK signaling promotes nuclear localization of FOXA transcription factor SGF1 via Ser91 phosphorylation Fulltext Access 12 Pages 2018
Junctional adhesion molecule C (JAM-C) dimerization aids cancer cell migration and metastasis Fulltext Access 12 Pages 2018
A novel role of sONE/NOS3/NO signaling cascade in mediating hydrogen sulphide bilateral effects on triple negative breast cancer progression Fulltext Access 12 Pages 2018
H2S is a key antisecretory molecule against cholera toxin-induced diarrhoea in mice: Evidence for non-involvement of the AC/cAMP/PKA pathway and AMPK Fulltext Access 12 Pages 2018
CYP2J2-derived EETs attenuated ethanol-induced myocardial dysfunction through inducing autophagy and reducing apoptosis Fulltext Access 12 Pages 2018
Long-term moderate exercise enhances specific proteins that constitute neurotrophin signaling pathway: A TMT-based quantitative proteomic analysis of rat plasma Fulltext Access 12 Pages 2018
6-Biphenylmethyl-3-hydroxypyrimidine-2,4-diones potently and selectively inhibited HIV reverse transcriptase-associated RNase H Fulltext Access 12 Pages 2018
Nicotine induces apoptosis in human osteoblasts via a novel mechanism driven by H2O2 and entailing Glyoxalase 1-dependent MG-H1 accumulation leading to TG2-mediated NF-kB desensitization: Implication for smokers-related osteoporosis Fulltext Access 12 Pages 2018
Short-term sleep deprivation with exposure to nocturnal light alters mitochondrial bioenergetics in Drosophila Fulltext Access 12 Pages 2018
Fatty Acid Metabolism is Associated With Disease Severity After H7N9 Infection Fulltext Access 12 Pages 2018
Oxidants produced by methylglyoxal-modified collagen trigger ER stress and apoptosis in skin fibroblasts Fulltext Access 12 Pages 2018
An elastase activity reporter for Electronic Paramagnetic Resonance (EPR) and Overhauser-enhanced Magnetic Resonance Imaging (OMRI) as a line-shifting nitroxide Fulltext Access 12 Pages 2018
Design, synthesis, and biological evaluation of a series of resorcinol-based N-benzyl benzamide derivatives as potent Hsp90 inhibitors Fulltext Access 12 Pages 2018
Design, synthesis and pharmacological evaluation of N-(5-chloro-2,4-dihydroxybenzoyl)-(R)-N-arylmethyl-1,2,3,4-tetrahydro-3-isoquinolinecarboxamides as potent Hsp90 inhibitors Fulltext Access 12 Pages 2018
Photoactive platinum(II) complexes of nonsteroidal anti-inflammatory drug naproxen: Interaction with biological targets, antioxidant activity and cytotoxicity Fulltext Access 12 Pages 2018
Synthesis and biological evaluation of 3-(2-aminoethyl) uracil derivatives as gonadotropin-releasing hormone (GnRH) receptor antagonists Fulltext Access 12 Pages 2018
Discovery of C-1 modified oseltamivir derivatives as potent influenza neuraminidase inhibitors Fulltext Access 12 Pages 2018
Mitochondria-targeted platinum(II) complexes induce apoptosis-dependent autophagic cell death mediated by ER-stress in A549 cancer cells Fulltext Access 12 Pages 2018
Binding mechanism investigations guiding the synthesis of novel condensed 1,4-dihydropyridine derivatives with L-/T-type calcium channel blocking activity Fulltext Access 12 Pages 2018