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Daneshyari Molecular Medicine Journas Latest Articles

Molecular Medicine Research Articles

Design, synthesis and biological evaluation of 1,4-Diazobicylco[3.2.2]nonane derivatives as α7-Nicotinic acetylcholine receptor PET/CT imaging agents and agonists for Alzheimer's disease
Fulltext Access 16 Pages 2018
Design, synthesis and biological evaluation of novel ferrocene-pyrazole derivatives containing nitric oxide donors as COX-2 inhibitors for cancer therapy
Fulltext Access 16 Pages 2018
Vasoactive intestinal peptide inhibits airway smooth muscle cell proliferation in a mouse model of asthma via the ERK1/2 signaling pathway
Fulltext Access 17 Pages 2018
More than a syllable in fib-ROS-is: The role of ROS on the fibrotic extracellular matrix and on cellular contacts
Fulltext Access 17 Pages 2018
Semi-automated system for concentrating 68Ga-eluate to obtain high molar and volume concentration of 68Ga-Radiopharmaca for preclinical applications
Fulltext Access 17 Pages 2018
Preliminary evaluation of a novel 18F-labeled PARP-1 ligand for PET imaging of PARP-1 expression in prostate cancer
Fulltext Access 17 Pages 2018
GuideLiner extension catheter-facilitated side strut stenting technique for the treatment of right coronary artery ostial in-stent restenosis
Fulltext Access 17 Pages 2018
KRIT1 loss-of-function induces a chronic Nrf2-mediated adaptive homeostasis that sensitizes cells to oxidative stress: Implication for Cerebral Cavernous Malformation disease
Fulltext Access 17 Pages 2018
Severe aortic stenosis in dextrocardia with situs invertus and anomalous single coronary ostium treated with transcatheter aortic valve replacement
Fulltext Access 17 Pages 2018
E3 ubiquitin ligase HECW2 targets PCNA and lamin B1
Fulltext Access 17 Pages 2018
Computer-aided drug discovery: Novel 3,9-disubstituted eudistomin U derivatives as potent antibacterial agents
Fulltext Access 17 Pages 2018
Expression of TUSC3 and its prognostic significance in colorectal cancer
Fulltext Access 17 Pages 2018
Catabolism of phenylacetic acid in Penicillium rubens. Proteome-wide analysis in response to the benzylpenicillin side chain precursor
Fulltext Access 17 Pages 2018
Hybrid epithelial/mesenchymal phenotype(s): The 'fittest' for metastasis?
Fulltext Access 17 Pages 2018
Interventions Targeting Glucocorticoid-Krüppel-like Factor 15-Branched-Chain Amino Acid Signaling Improve Disease Phenotypes in Spinal Muscular Atrophy Mice
Fulltext Access 17 Pages 2018
The Human Cytomegalovirus Strain DB Activates Oncogenic Pathways in Mammary Epithelial Cells
Fulltext Access 17 Pages 2018
HtrA1 Mediated Intracellular Effects on Tubulin Using a Polarized RPE Disease Model
Fulltext Access 17 Pages 2018
PERK inhibition attenuates the abnormalities of the secretory pathway and the increased apoptotic rate induced by SIL1 knockdown in HeLa cells
Fulltext Access 17 Pages 2018
β-amino alcohols and their respective 2-phenyl-N-alkyl aziridines as potential DNA minor groove binders
Fulltext Access 17 Pages 2018
Design, synthesis and structure-activity relationship of a focused library of β-phenylalanine derivatives as novel eEF2K inhibitors with apoptosis-inducing mechanisms in breast cancer
Fulltext Access 17 Pages 2018
Discovery of novel piperonyl derivatives as diapophytoene desaturase inhibitors for the treatment of methicillin-, vancomycin- and linezolid-resistant Staphylococcus aureus infections
Fulltext Access 17 Pages 2018
Association of increased microvessel density with skeletal extramedullary disease relapse in multiple myeloma patients who have skeletal extramedullary disease at diagnosis
Fulltext Access 17 Pages 2018
Putative model based on iTRAQ proteomics for Spirulina morphogenesis mechanisms
Fulltext Access 17 Pages 2018
Long-term results of a sirolimus-eluting stent with biodegradable polymer (RAPSTROM™) in de novo coronary stenoses
Fulltext Access 17 Pages 2018
Photoinduced anticancer activity studies of iridium(III) complexes targeting mitochondria and tubules
Fulltext Access 17 Pages 2018
The role of NADPH oxidases in diabetic cardiomyopathy
Fulltext Access 17 Pages 2018
Redox biosensors in a context of multiparameter imaging
Fulltext Access 17 Pages 2018
Soluble ST2, a preeclampsia-related cytokine receptor, is transported bi-directionally across the placenta
Fulltext Access 18 Pages 2018
Bailout surgical explantation of a transcatheter valve-in-valve for subacute thrombosis: When there is no time for anticoagulation
Fulltext Access 18 Pages 2018
Hematological phenotypes in children according to the α-globin genotypes
Fulltext Access 18 Pages 2018
Role of tissue-specific promoter DNA methylation in regulating the human EKLF gene
Fulltext Access 18 Pages 2018
Label-free quantitative proteomics of rat hypothalamus under fever induced by LPS and PGE2
Fulltext Access 18 Pages 2018
Mass spectrometry and DigiWest technology emphasize protein acetylation profile from Quisinostat-treated HuT78 CTCL cell line
Fulltext Access 18 Pages 2018
SIRT1 and microRNAs: The role in breast, lung and prostate cancers
Fulltext Access 18 Pages 2018
Identification of a novel cofilin-related molecule (Der f 31) as an allergen from Dermatophagoides farinae
Fulltext Access 18 Pages 2018
Impact of marital status on outcomes following ST-segment elevation myocardial infarction
Fulltext Access 18 Pages 2018
Orthogonal potency analysis of mesenchymal stromal cell function during ex vivo expansion
Fulltext Access 18 Pages 2018
Investigation of relationship between precursor of miRNA-944 and its mature form in lung squamous-cell carcinoma - the diagnostic value
Fulltext Access 18 Pages 2018
Role of miR-452-5p in the tumorigenesis of prostate cancer: A study based on the Cancer Genome Atl(TCGA), Gene Expression Omnibus (GEO), and bioinformatics analysis
Fulltext Access 18 Pages 2018
VEGFR-2 as a novel predictor of survival in gastric cancer: A systematic review and meta-analysis

Fulltext Access 18 Pages 2018
Matrix metalloproteinases are regulated by MicroRNA 320 in macrophages and are associated with aortic dissection
Fulltext Access 18 Pages 2018
Studies on 2-phenylquinoline Staphylococcus aureus NorA efflux pump inhibitors: New insights on the C-6 position
Fulltext Access 18 Pages 2018
Studying allergic inflammation and spirometry over menstrual cycles in well-controlled asthmatic women: Changes in progesterone and estradiol affect neither FENO levels nor lung function
Fulltext Access 18 Pages 2018
Inhaled nebulized sodium nitrite decreases pulmonary artery pressure in β-thalassemia patients with pulmonary hypertension
Fulltext Access 18 Pages 2018
Expression and clinicopathological significance of hematopoietic pre-B cell leukemia transcription factor-interacting protein in cervical carcinoma
Fulltext Access 18 Pages 2018
Circ-8073 regulates CEP55 by sponging miR-449a to promote caprine endometrial epithelial cells proliferation via the PI3K/AKT/mTOR pathway
Fulltext Access 18 Pages 2018
Synthesis, toxicities and bio-activities of manganese complexes with CO and H2S dual donors
Fulltext Access 18 Pages 2018
Dihydropyrimidinone/1,2,3-triazole hybrid molecules: Synthesis and anti-varicella-zoster virus (VZV) evaluation
Fulltext Access 18 Pages 2018
CD73 inhibition by purine cytotoxic nucleoside analogue-based diphosphonates
Fulltext Access 18 Pages 2018
Redox-signals and macrophage biology
Fulltext Access 18 Pages 2018
Development of an in vitro model to study hepatitis C virus effects on hepatocellular lipotoxicity and lipid metabolism
Fulltext Access 18 Pages 2018
Discovery of biphenyl-substituted diarylpyrimidines as non-nucleoside reverse transcriptase inhibitors with high potency against wild-type and mutant HIV-1
Fulltext Access 18 Pages 2018
Erythrocyte heme‑oxygenation status indicated as a risk factor in prehypertension by Raman spectroscopy
Fulltext Access 19 Pages 2018
Coordination and redox interactions of β-lactam antibiotics with Cu2+ in physiological settings and the impact on antibacterial activity
Fulltext Access 19 Pages 2018
Design, synthesis, and evaluation of cystargolide-based β-lactones as potent proteasome inhibitors
Fulltext Access 19 Pages 2018
Current insight into a cancer-implicated long noncoding RNA ZFAS1 and correlative functional mechanisms involved
Fulltext Access 19 Pages 2018
Deciphering OPA1 mutations pathogenicity by combined analysis of human, mouse and yeast cell models
Fulltext Access 19 Pages 2018
CCR7 preservation via histone deacetylase inhibition promotes epithelial-mesenchymal transition of hepatocellular carcinoma cells
Fulltext Access 19 Pages 2018
Crosstalk between reactive oxygen species and nitric oxide in plants: Key role of S-nitrosoglutathione reductase
Fulltext Access 19 Pages 2018
Spread of MCR-3 Colistin Resistance in China: An Epidemiological, Genomic and Mechanistic Study
Fulltext Access 19 Pages 2018
Membrane cholesterol modulates STEAP2 conformation during dynamic intracellular trafficking processes leading to broad subcellular distribution
Fulltext Access 19 Pages 2018
Protective C allele of the single-nucleotide polymorphism rs1335532 is associated with strong binding of Ascl2 transcription factor and elevated CD58 expression in B-cells
Fulltext Access 19 Pages 2018
Fetal presentation of congenital dyserythropoietic anemia type 1 with novel compound heterozygous CDAN1 mutations
Fulltext Access 19 Pages 2018
The TRPM2 ion channel contributes to cytokine hyperproduction in a mouse model of Down Syndrome
Fulltext Access 19 Pages 2018
Untimely oxidative stress in β-cells leads to diabetes - Role of circadian clock in β-cell function
Fulltext Access 19 Pages 2018
Prazosin induced lysosomal tubulation interferes with cytokinesis and the endocytic sorting of the tumour antigen CD98hc
Fulltext Access 19 Pages 2018
Store-independent coupling between the Secretory Pathway Ca2+ transport ATPase SPCA1 and Orai1 in Golgi stress and Hailey-Hailey disease
Fulltext Access 19 Pages 2018
PDGF in organ fibrosis
Fulltext Access 19 Pages 2018
Enediynes bearing polyfluoroaryl sulfoxide as new antiproliferative agents with dual targeting of microtubules and DNA
Fulltext Access 19 Pages 2018
Design, synthesis, biological evaluation and in vivo testing of dual phosphodiesterase 5 (PDE5) and histone deacetylase 6 (HDAC6)-selective inhibitors for the treatment of Alzheimer's disease
Fulltext Access 19 Pages 2018
The E3 ligase for metastasis associated 1 protein, TRIM25, is targeted by microRNA-873 in hepatocellular carcinoma
Fulltext Access 19 Pages 2018
Discovery of 4-((N-(2-(dimethylamino)ethyl)acrylamido)methyl)-N-(4-methyl-3-((4-(pyridin-3-yl)pyrimidin-2-yl)amino)phenyl)benzamide (CHMFL-PDGFR-159) as a highly selective type II PDGFRα kinase inhibitor for PDGFRα driving chronic eosinophilic leukemia
Fulltext Access 19 Pages 2018
NUSAP1 gene silencing inhibits cell proliferation, migration and invasion through inhibiting DNMT1 gene expression in human colorectal cancer
Fulltext Access 19 Pages 2018
Aberrant endoplasmic reticulum stress mediates coronary artery spasm through regulating MLCK/MLC2 pathway
Fulltext Access 19 Pages 2018
Evaluation of a chloride-based 89Zr isolation strategy using a tributyl phosphate (TBP)-functionalized extraction resin
Fulltext Access 19 Pages 2018
The relationship between EGFR mutation status and clinic-pathologic features in pulmonary adenocarcinoma
Fulltext Access 19 Pages 2018
Lactam hybrid analogues of solonamide B and autoinducing peptides as potent S. aureus AgrC antagonists
Fulltext Access 20 Pages 2018
SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins
Fulltext Access 20 Pages 2018
Expression of RNA-binding protein LIN28 in classic gastric hepatoid carcinomas, gastric fetal type gastrointestinal adenocarcinomas, and hepatocellular carcinomas: An immunohistochemical study with comparison to SALL4, alpha-fetoprotein, glypican-3, and H
Fulltext Access 20 Pages 2018
Phenylpyridine-2-ylguanidines and rigid mimetics as novel inhibitors of TNFα overproduction: Beneficial action in models of neuropathic pain and of acute lung inflammation
Fulltext Access 20 Pages 2018
Design, synthesis and biological evaluation of a series of novel 2-benzamide-4-(6-oxy-N-methyl-1-naphthamide)-pyridine derivatives as potent fibroblast growth factor receptor (FGFR) inhibitors
Fulltext Access 20 Pages 2018
Design, synthesis and bioevaluation of 2-mercapto-6-phenylpyrimidine-4-carboxylic acid derivatives as potent xanthine oxidase inhibitors
Fulltext Access 20 Pages 2018
Astroglial and microglial contributions to iron metabolism disturbance in Parkinson's disease
Fulltext Access 20 Pages 2018
Common variants of ROCKs and the risk of hypertension, and stroke: Two case-control studies and a follow-up study in Chinese Han population
Fulltext Access 20 Pages 2018
Rational design of mitochondria-targeted pyruvate dehydrogenase kinase 1 inhibitors with improved selectivity and antiproliferative activity
Fulltext Access 20 Pages 2018
NCS-1 is a regulator of calcium signaling in health and disease
Fulltext Access 20 Pages 2018
Four new antitumor metabolites isolated from a mutant 3-f-31 strain derived from Penicillium purpurogenum G59
Fulltext Access 20 Pages 2018
Redox clocks: Time to rethink redox interventions
Fulltext Access 20 Pages 2018
Alkaline ceramidase 3 promotes growth of hepatocellular carcinoma cells via regulating S1P/S1PR2/PI3K/AKT signaling
Fulltext Access 20 Pages 2018
8-Nitro-cGMP is a promoter of osteoclast differentiation induced by RANKL
Fulltext Access 20 Pages 2018
PAG1 promotes the inherent radioresistance of laryngeal cancer cells via activation of STAT3
Fulltext Access 20 Pages 2018
Renal ischemia/reperfusion-induced mitophagy protects against renal dysfunction via Drp1-dependent-pathway
Fulltext Access 20 Pages 2018
Dysfunction of cholesterol sensor SCAP promotes inflammation activation in THP-1 macrophages
Fulltext Access 20 Pages 2018
Tr1 responses are elevated in asymptomatic H. pylori-infected individuals and are functionally impaired in H. pylori-gastric cancer patients
Fulltext Access 20 Pages 2018
Differential protein expression of hippocampal cells associated with heavy metals (Pb, As, and MeHg) neurotoxicity: Deepening into the molecular mechanism of neurodegenerative diseases
Fulltext Access 20 Pages 2018
Outcomes of transcatheter aortic valve replacement using a minimalist approach
Fulltext Access 20 Pages 2018
Chronic exposure of the RAW246.7 macrophage cell line to H2O2 leads to increased catalase expression
Fulltext Access 21 Pages 2018
Nrf2 protects against acute lung injury and inflammation by modulating TLR4 and Akt signaling
Fulltext Access 21 Pages 2018
Extracorporeal myocardial shockwave therapy; a precious blast for refractory angina patients
Fulltext Access 21 Pages 2018
Coronary access following TAVI - Selective coronary engagement using balloon-assisted tracking of a guide catheter extension
Fulltext Access 21 Pages 2018
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