Regulation of VDAC1 contributes to the cardioprotective effects of penehyclidine hydrochloride during myocardial ischemia/reperfusion Fulltext Access 24 Pages 2018
Mechanism responsible for inhibitory effect of indirubin 3â²-oxime on anticancer agent-induced YB-1 nuclear translocation in HepG2 human hepatocellular carcinoma cells Fulltext Access 24 Pages 2018
B2-Lymphocyte responses to oxidative stress-derived antigens contribute to the evolution of nonalcoholic fatty liver disease (NAFLD) Fulltext Access 24 Pages 2018
ARF promotes the degradation of the Epidermal Growth Factor Receptor by the lysosome Fulltext Access 24 Pages 2018
Staphylococcal enterotoxin C2 stimulated the maturation of bone marrow derived dendritic cells via TLR-NFκB signaling pathway Fulltext Access 24 Pages 2018
Deuterated 18F-9-O-hexadeutero-3-fluoropropoxyl-(+)-dihydrotetrabenazine (D6-FP-(+)-DTBZ): A vesicular monoamine transporter 2 (VMAT2) imaging agent Fulltext Access 24 Pages 2018
Nrf2 signaling and autophagy are complementary in protecting breast cancer cells during glucose deprivation Fulltext Access 24 Pages 2018
Activation of Nrf2 by Ginsenoside Rh3 protects retinal pigment epithelium cells and retinal ganglion cells from UV Fulltext Access 24 Pages 2018
GABAergic over-inhibition, a promising hypothesis for cognitive deficits in Down syndrome Fulltext Access 24 Pages 2018
Intraobserver and interobserver variability of the bone marrow burden (BMB) score for the assessment of disease severity in Gaucher disease. Possible impact of reporting experience Fulltext Access 24 Pages 2018
Tanshindiol C inhibits oxidized low-density lipoprotein induced macrophage foam cell formation via a peroxiredoxin 1 dependent pathway Fulltext Access 24 Pages 2018
Low shear stress induces vascular eNOS uncoupling via autophagy-mediated eNOS phosphorylation Fulltext Access 24 Pages 2018
Subclinical and clinical chorioamnionitis, fetal vasculitis, and risk for preterm birth: A cohort study Fulltext Access 24 Pages 2018
Molecular functions and specific roles of circRNAs in the cardiovascular system Fulltext Access 24 Pages 2018
Involvement of microRNAs-MMPs-E-cadherin in the migration and invasion of gastric cancer cells infected with Helicobacter pylori Fulltext Access 24 Pages 2018
MiR-449a suppresses cell migration and invasion by targeting PLAGL2 in breast cancer Fulltext Access 24 Pages 2018
Up-regulation of miR-122 protects against neuronal cell death in ischemic stroke through the heat shock protein 70-dependent NF-κB pathway by targeting FOXO3 Fulltext Access 24 Pages 2018
In silico analysis of the potential mechanism of telocinobufagin on breast cancer MCF-7 cells Fulltext Access 24 Pages 2018
MiR-223/Pknox1 axis protects mice from CVB3-induced viral myocarditis by modulating macrophage polarization Fulltext Access 24 Pages 2018
HtrA3 is a cellular partner of cytoskeleton proteins and TCP1α chaperonin Fulltext Access 24 Pages 2018
Merging in-silico and in vitro salivary protein complex partners using the STRING database: A tutorial Fulltext Access 24 Pages 2018
Chlorambucil-conjugated platinum(IV) prodrugs to treat triple-negative breast cancer in vitro and in vivo Fulltext Access 24 Pages 2018
Design, synthesis and in vitro anti-Zika virus evaluation of novel Sinefungin derivatives Fulltext Access 24 Pages 2018
Osteopontin promotes collagen I synthesis in hepatic stellate cells by miRNA-129-5p inhibition Fulltext Access 24 Pages 2018
Anti-tumor effect of AZD8055 against neuroblastoma cells in vitro and in vivo Fulltext Access 24 Pages 2018
New developments in non-quinolone-based antibiotics for the inhibiton of bacterial gyrase and topoisomerase IV Fulltext Access 24 Pages 2018
Inhibition of mTOR complexes protects cancer cells from glutamine starvation induced cell death by restoring Akt stability Fulltext Access 24 Pages 2018
Design, synthesis and biological evaluation of novel trimethylangelicin analogues targeting nuclear factor kB (NF-kB) Fulltext Access 24 Pages 2018
Design, synthesis and biological evaluation of C(4) substituted monobactams as antibacterial agents against multidrug-resistant Gram-negative bacteria Fulltext Access 24 Pages 2018
By modulating α2β1 integrin signalling, gastrin increases adhesion oF AGS-GR gastric cancer cells Fulltext Access 24 Pages 2018
β,γ-diamino acids as building blocks for new analogues of Gramicidin S: Synthesis and biological activity Fulltext Access 24 Pages 2018
Desogestrel down-regulates PHOX2B and its target genes in progesterone responsive neuroblastoma cells Fulltext Access 24 Pages 2018
Highly convergent synthesis and antiviral activity of (E)-but-2-enyl nucleoside phosphonoamidates Fulltext Access 24 Pages 2018
Cytotoxicity, molecular modeling, cell cycle arrest, and apoptotic induction induced by novel tetrahydro-[1,2,4]triazolo[3,4-a]isoquinoline chalcones Fulltext Access 24 Pages 2018
BCA3 contributes to the malignant progression of hepatocellular carcinoma through AKT activation and NF-κB translocation Fulltext Access 25 Pages 2018
Stem cell transcription factor SOX2 in synovial sarcoma and other soft tissue tumors Fulltext Access 25 Pages 2018
Follicular helper T cells promote the effector functions of CD8+ T cells via the provision of IL-21, which is downregulated due to PD-1/PD-L1-mediated suppression in colorectal cancer Fulltext Access 25 Pages 2018
68Ga[Ga]-Galmydar: Biodistribution and radiation dosimetry studies in rodents Fulltext Access 25 Pages 2018
Altered O-glycosylation is associated with inherent radioresistance and malignancy of human laryngeal carcinoma Fulltext Access 25 Pages 2018
MiR-1260b promotes the migration and invasion in non-small cell lung cancer via targeting PTPRK Fulltext Access 25 Pages 2018
Association between NME1 polymorphisms and cancer susceptibility: A meta-analysis based on 1644 cases and 2038 controls Fulltext Access 25 Pages 2018
DNMT1 is associated with cell cycle and DNA replication gene sets in diffuse large B-cell lymphoma Fulltext Access 25 Pages 2018
Two novel mutations (p.(Ser160Pro) and p.(Arg472Cys)) causing glucose-6-phosphate isomerase deficiency are associated with erythroid dysplasia and inappropriately suppressed hepcidin Fulltext Access 25 Pages 2018
Systematic isolated post-dilatation of the side branch as part of the provisional stent technique in the percutaneous treatment of coronary bifurcations. CR12 Registry Fulltext Access 25 Pages 2018
Transgenic expression of the RNA binding protein IMP2 stabilizes miRNA targets in murine microsteatosis Fulltext Access 25 Pages 2018
TPC2 mediates autophagy progression and extracellular vesicle secretion in cancer cells Fulltext Access 25 Pages 2018
Long non-coding RNA DLX6-AS1 is upregulated in preeclampsia and modulates migration and invasion of trophoblasts through the miR-376c/GADD45A axis Fulltext Access 25 Pages 2018
Mesenchymal stem cells up-regulate the invasive potential of prostate cancer cells via the eotaxin-3/CCR3 axis Fulltext Access 25 Pages 2018
A β-glucuronidase-responsive albumin-binding prodrug for potential selective kinase inhibitor-based cancer chemotherapy Fulltext Access 25 Pages 2018
NCAM140 is translocated into the nucleus by an importin-β1-dependent mechanism Fulltext Access 25 Pages 2018
Asymmetrical meta-methoxylated diarylpentanoids: Rational design, synthesis and anti-cancer evaluation in-vitro Fulltext Access 25 Pages 2018
Design and synthesis of furyl/thineyl pyrroloquinolones based on natural alkaloid perlolyrine, lead to the discovery of potent and selective PDE5 inhibitors Fulltext Access 25 Pages 2018
Translationally controlled tumor protein (TCTP) is required for TGF-β1 induced epithelial to mesenchymal transition and influences cytoskeletal reorganization Fulltext Access 25 Pages 2018
Modelling human myoblasts survival upon xenotransplantation into immunodeficient mouse muscle Fulltext Access 25 Pages 2018
Ascorbic acid increases SVCT2 localization at the plasma membrane by accelerating its trafficking from early secretory compartments and through the endocytic-recycling pathway Fulltext Access 25 Pages 2018
Mapping three guanine oxidation products along DNA following exposure to three types of reactive oxygen species Fulltext Access 25 Pages 2018
Hydroxychavicol, a key ingredient of Piper betle induces bacterial cell death by DNA damage and inhibition of cell division Fulltext Access 25 Pages 2018
Berberine exerts antioxidant effects via protection of spiral ganglion cells against cytomegalovirus-induced apoptosis Fulltext Access 25 Pages 2018
A novel case of ACOX2 deficiency leads to recognition of a third human peroxisomal acyl-CoA oxidase Fulltext Access 25 Pages 2018
Regioselective synthesis of 3,4-diaryl-5-unsubstituted isoxazoles, analogues of natural cytostatic combretastatin A4 Fulltext Access 25 Pages 2018
Dual-targeting antitumor hybrids derived from Pt(IV) species and millepachine analogues Fulltext Access 25 Pages 2018
Antibacterial and anti-TB tat-peptidomimetics with improved efficacy and half-life Fulltext Access 25 Pages 2018
Dual-tail arylsulfone-based benzenesulfonamides differently match the hydrophobic and hydrophilic halves of human carbonic anhydrases active sites: Selective inhibitors for the tumor-associated hCA IX isoform Fulltext Access 25 Pages 2018
Structure-based lead optimization to improve antiviral potency and ADMET properties of phenyl-1H-pyrrole-carboxamide entry inhibitors targeted to HIV-1 gp120 Fulltext Access 25 Pages 2018
Synthesis, antiproliferative activity and mechanism of gallium(III)-thiosemicarbazone complexes as potential anti-breast cancer agents Fulltext Access 25 Pages 2018
Structure-activity relationships in fungal nucleobases transporters as dissected by the inhibitory effects of novel purine analogues Fulltext Access 25 Pages 2018
MMB triazole analogs are potent NF-κB inhibitors and anti-cancer agents against both hematological and solid tumor cells Fulltext Access 25 Pages 2018
Novel coumarin-pyrazole carboxamide derivatives as potential topoisomerase II inhibitors: Design, synthesis and antibacterial activity Fulltext Access 25 Pages 2018
Magnetic capture of polydopamine-encapsulated Hela cells for the analysis of cell surface proteins Fulltext Access 25 Pages 2018
Salivary biomarkers for the diagnosis and monitoring of neurological diseases Fulltext Access 25 Pages 2018
CD18-mediated adhesion is required for the induction of a proinflammatory phenotype in lung epithelial cells by mononuclear cell-derived extracellular vesicles Fulltext Access 25 Pages 2018
Hypoxia-induced HMGB1 expression of HCC promotes tumor invasiveness and metastasis via regulating macrophage-derived IL-6 Fulltext Access 25 Pages 2018
Caveolin-1 promotes pituitary adenoma cells migration and invasion by regulating the interaction between EGR1 and KLF5 Fulltext Access 25 Pages 2018
Heart failure and endothelial nitric oxide synthase G894T gene polymorphism frequency variations within ancestries Fulltext Access 25 Pages 2018
Increased phosphorylation of eNOS in nasal polyps of chronic rhinosinusitis patients can be diminished by 1,8-cineol Fulltext Access 25 Pages 2018
Kinase-independent role of nuclear RIPK1 in regulating parthanatos through physical interaction with PARP1 upon oxidative stress Fulltext Access 25 Pages 2018
Reciprocal regulation of the Cadherin-11/Stat3 axis by caveolin-1 in mouse fibroblasts and lung carcinoma cells Fulltext Access 26 Pages 2018
miR144-3p inhibits PMVECs excessive proliferation in angiogenesis of hepatopulmonary syndrome via Tie2 Fulltext Access 26 Pages 2018
MicroRNA-630 inhibits breast cancer progression by directly targeting BMI1 Fulltext Access 26 Pages 2018
MiR-155 targets PTCH1 to mediate endothelial progenitor cell dysfunction caused by high glucose Fulltext Access 26 Pages 2018
Serum miR-130b level, an ideal marker for monitoring the recurrence and prognosis of primary hepatocellular carcinoma after radiofrequency ablation treatment Fulltext Access 26 Pages 2018
Cancer stem cell-like population is preferentially suppressed by EGFR-TKIs in EGFR-mutated PC-9 tumor models Fulltext Access 26 Pages 2018
Human skin barrier formation takes place via a cubic to lamellar lipid phase transition as analyzed by cryo-electron microscopy and EM-simulation Fulltext Access 26 Pages 2018
Tisp40 deficiency limits renal inflammation and promotes tubular cell proliferation in renal ischemia reperfusion injury Fulltext Access 26 Pages 2018
SIRT2 reduces actin polymerization and cell migration through deacetylation and degradation of HSP90 Fulltext Access 26 Pages 2018
Metastasis-associated protein 1 (MTA1) in gastric cancer tissues is positively associated with poorer prognosis Fulltext Access 26 Pages 2018
Rap1b enhances the invasion and migration of hepatocellular carcinoma cells by up-regulating Twist 1 Fulltext Access 26 Pages 2018
Procyanidin B2 protects rats from paraquat-induced acute lung injury by inhibiting NLRP3 inflammasome activation Fulltext Access 26 Pages 2018
Oocyte-specific deletion of Gsα induces oxidative stress and deteriorates oocyte quality in mice Fulltext Access 26 Pages 2018
Nitric oxide induces epidermal stem cell de-adhesion by targeting integrin β1 and Talin via the cGMP signalling pathway Fulltext Access 26 Pages 2018
Cell-free therapy based on adipose tissue stem cell-derived exosomes promotes wound healing via the PI3K/Akt signaling pathway Fulltext Access 26 Pages 2018
MiR-21-5p, miR-34a, and human telomerase RNA component as surrogate markers for cervical cancer progression Fulltext Access 26 Pages 2018