Clinical significance of intracoronary thrombus aspirated during primary percutaneous intervention: An immunohistopathological study Fulltext Access 28 Pages 2018
NADPH oxidase 5 promotes proliferation and fibrosis in human hepatic stellate cells Fulltext Access 28 Pages 2018
Exploring parasite heterogeneity using single-cell RNA-seq reveals a gene signature among sexual stage Plasmodium falciparum parasites Fulltext Access 28 Pages 2018
Extracellular superoxide dismutase (SOD3) regulates oxidative stress at the vitreoretinal interface Fulltext Access 28 Pages 2018
Dr. Jekyll and Mr. Hyde: Oxidizable phenol-generated reactive oxygen species enhance sulforaphane's antioxidant response element activation, even as they suppress Nrf2 protein accumulation Fulltext Access 28 Pages 2018
Keto-enol-based modification on piperlongumine to generate a potent Cu(II) ionophore that triggers redox imbalance and death of HepG2 cells Fulltext Access 28 Pages 2018
An innate immune response and altered nuclear receptor activation defines the spinal cord transcriptome during alpha-tocopherol deficiency in Ttpa-null mice Fulltext Access 28 Pages 2018
ETS-domain containing protein (Elk1) suppression protects cortical neurons against oxygen-glucose deprivation injury Fulltext Access 28 Pages 2018
FOXO1 cysteine-612 mediates stimulatory effects of the coregulators CBP and PGC1α on FOXO1 basal transcriptional activity Fulltext Access 28 Pages 2018
Human keratinocyte cultures (HaCaT) can be infected by DENV, triggering innate immune responses that include IFNλ and LL37 Fulltext Access 28 Pages 2018
Detection of the formyl radical by EPR spin-trapping and mass spectrometry Fulltext Access 28 Pages 2018
Prognostic significance of carbonic anhydrase IX overexpression in stage III non-small cell lung cancer patients after neoadjuvant treatment Fulltext Access 28 Pages 2018
High expression of enhancer RNA MARC1 or its activation by DHT is associated with the malignant behavior in bladder cancer Fulltext Access 28 Pages 2018
Label-free FTIR spectroscopy detects and visualizes the early stage of pulmonary micrometastasis seeded from breast carcinoma Fulltext Access 28 Pages 2018
Mild ozonisation activates antioxidant cell response by the Keap1/Nrf2 dependent pathway Fulltext Access 28 Pages 2018
Overexpression of YAP1 in EGFR mutant lung adenocarcinoma prior to tyrosine kinase inhibitor therapy is associated with poor survival Fulltext Access 28 Pages 2018
Preclinical evaluation of heat-denatured [18F]FDG-labeled red blood cells for detecting splenic tissues with PET in rats Fulltext Access 28 Pages 2018
Imaging of isoproterenol-induced myocardial injury with 18F labeled fluoroglucaric acid in a rat model Fulltext Access 28 Pages 2018
Microscale radiosynthesis, preclinical imaging and dosimetry study of [18F]AMBF3-TATE: A potential PET tracer for clinical imaging of somatostatin receptors Fulltext Access 28 Pages 2018
DA-Raf, a dominant-negative antagonist of the Ras-ERK pathway, is a putative tumor suppressor Fulltext Access 28 Pages 2018
The role of C1QBP in CSF-1-dependent PKCζ activation and macrophage migration Fulltext Access 28 Pages 2018
Involvement of FFA1 and FFA4 in the regulation of cellular functions during tumor progression in colon cancer cells Fulltext Access 28 Pages 2018
Assessment of the hepatocytic differentiation ability of human skin-derived ABCB5+ stem cells Fulltext Access 28 Pages 2018
PTEN silencing enhances neuronal proliferation and differentiation by activating PI3K/Akt/GSK3β pathway in vitro Fulltext Access 28 Pages 2018
Progranulin ameliorates coxsackievirus-B3-induced viral myocarditis by downregulating Th1 and Th17 cells Fulltext Access 28 Pages 2018
Reduced substrate stiffness promotes M2-like macrophage activation and enhances peroxisome proliferator-activated receptor γ expression Fulltext Access 28 Pages 2018
ISG15 promotes esophageal squamous cell carcinoma tumorigenesis via c-MET/Fyn/β-catenin signaling pathway Fulltext Access 28 Pages 2018
Vitamin A deficiency induces endoplasmic reticulum stress and apoptosis in pancreatic islet cells: Implications of stearoyl-CoA desaturase 1-mediated oleic acid synthesis Fulltext Access 28 Pages 2018
Secreted AGR2 promotes invasion of colorectal cancer cells via Wnt11-mediated non-canonical Wnt signaling Fulltext Access 28 Pages 2018
Oxidative post-translational modification of βeta 2-glycoprotein I in the pathophysiology of the anti-phospholipid syndrome Fulltext Access 28 Pages 2018
Methylation status of ORMDL3 regulates cytokine production and p-ERK/MMP9 pathway expression Fulltext Access 28 Pages 2018
A comprehensive review of chalcone derivatives as antileishmanial agents Fulltext Access 28 Pages 2018
Synthesis and antitumour evaluation of mono- and multinuclear [2+1] tricarbonylrhenium(I) complexes Fulltext Access 28 Pages 2018
Synthesis of novel 4-functionalized 1,5-diaryl-1,2,3-triazoles containing benzenesulfonamide moiety as carbonic anhydrase I, II, IV and IX inhibitors Fulltext Access 28 Pages 2018
6,7-Dimorpholinoalkoxy quinazoline derivatives as potent EGFR inhibitors with enhanced antiproliferative activities against tumor cells Fulltext Access 28 Pages 2018
Discovery and development of novel salicylate synthase (MbtI) furanic inhibitors as antitubercular agents Fulltext Access 28 Pages 2018
Design, synthesis and in vitro biological evaluation of novel [1,2,3]triazolo[4,5-d]pyrimidine derivatives containing a thiosemicarbazide moiety Fulltext Access 28 Pages 2018
Synthesis and biological evaluation of 4-amino-5-cinnamoylthiazoles as chalcone-like anticancer agents Fulltext Access 28 Pages 2018
Ligand-selective small molecule modulators of the constitutively active vGPCR US28 Fulltext Access 28 Pages 2018
Green approach for the synthesis of thiophenyl pyrazoles and isoxazoles by adopting 1,3-dipolar cycloaddition methodology and their antimicrobial activity Fulltext Access 28 Pages 2018
Brg1 regulates pro-lipogenic transcription by modulating SREBP activity in hepatocytes Fulltext Access 28 Pages 2018
Syntheses of C-ring modified dehydroabietylamides and their cytotoxic activity Fulltext Access 28 Pages 2018
Tropospheric ozone affects SRB1 levels via oxidative post-translational modifications in lung cells Fulltext Access 28 Pages 2018
Synthesis and biological evaluation of (1-aryl-1H-pyrazol-4-yl) (3,4,5-trimethoxyphenyl)methanone derivatives as tubulin inhibitors Fulltext Access 28 Pages 2018
Exosomes derived from PEDF modified adipose-derived mesenchymal stem cells ameliorate cerebral ischemia-reperfusion injury by regulation of autophagy and apoptosis Fulltext Access 28 Pages 2018
PI3K/AKT/mTOR activation and autophagy inhibition plays a key role in increased cholesterol during IL-17A mediated inflammatory response in psoriasis Fulltext Access 28 Pages 2018
BRMS1L suppresses ovarian cancer metastasis via inhibition of the β-catenin-wnt pathway Fulltext Access 28 Pages 2018
Metabolic studies of a patient harbouring a novel S487L mutation in the catalytic subunit of AMPK Fulltext Access 28 Pages 2018
Design, synthesis, and biological evaluation of novel pan agonists of FFA1, PPARγ and PPARδ Fulltext Access 29 Pages 2018
In vitro-induced M2 type macrophages induces the resistance of prostate cancer cells to cytotoxic action of NK cells Fulltext Access 29 Pages 2018
Inhibition of LDL oxidation and inflammasome assembly by nitroaliphatic derivatives. Potential use as anti-inflammatory and anti-atherogenic agents Fulltext Access 29 Pages 2018
Up-regulated lncRNA-MSX2P1 promotes the growth of IL-22-stimulated keratinocytes by inhibiting miR-6731-5p and activating S100A7 Fulltext Access 29 Pages 2018
Predicting response to sepantronium bromide (YM155), a survivin suppressant, by PET imaging with [11C]YM155 Fulltext Access 29 Pages 2018
Effects of farnesoid-X-receptor SUMOylation mutation on myocardial ischemia/reperfusion injury in mice Fulltext Access 29 Pages 2018
The role of Ca2+ in oocyte activation during In Vitro fertilization: Insights into potential therapies for rescuing failed fertilization Fulltext Access 29 Pages 2018
Intraprocedural invasive hemodynamic parameters as predictors of short- and long-term outcomes in patients undergoing transcatheter aortic valve replacement Fulltext Access 29 Pages 2018
Redox-sensitive signaling in inflammatory T cells and in autoimmune disease Fulltext Access 29 Pages 2018
Branched pentapeptides as potent inhibitors of the vascular endothelial growth factor 165 binding to Neuropilin-1: Design, synthesis and biological activity Fulltext Access 29 Pages 2018
Synthesis of 5H-pyrido[3,2-b]pyrrolizin-5-one tripentone analogs with antitumor activity Fulltext Access 29 Pages 2018
miR-125a-5p regulation increases phosphorylation of FAK that contributes to imatinib resistance in gastrointestinal stromal tumors Fulltext Access 29 Pages 2018
Design, synthesis, biological evaluation and docking studies of new 3-(4,5-dihydro-1H-pyrazol/isoxazol-5-yl)-2-phenyl-1H-indole derivatives as potent antioxidants and 15-lipoxygenase inhibitors Fulltext Access 29 Pages 2018
Erythrocyte SOD1 activity, but not SOD1 polymorphisms, is associated with ICU mortality in patients with septic shock Fulltext Access 29 Pages 2018
On the role of IgG4 in inflammatory conditions: lessons for IgG4-related disease Fulltext Access 29 Pages 2018
Prolactin regulatory element-binding (PREB) protein regulates hepatic glucose homeostasis Fulltext Access 29 Pages 2018
ERK5/KLF2 activation is involved in the reducing effects of puerarin on monocyte adhesion to endothelial cells and atherosclerotic lesion in apolipoprotein E-deficient mice Fulltext Access 29 Pages 2018
TIGIT-Fc alleviates acute graft-versus-host disease by suppressing CTL activation via promoting the generation of immunoregulatory dendritic cells Fulltext Access 29 Pages 2018
Telomere length alterations in microsatellite stable colorectal cancer and association with the immune response Fulltext Access 29 Pages 2018
An improved 99mTc-HYNIC-(Ser)3-LTVSPWY peptide with EDDA/tricine as co-ligands for targeting and imaging of HER2 overexpression tumor Fulltext Access 29 Pages 2018
Nitrogen-containing ecdysteroid derivatives vs. multi-drug resistance in cancer: Preparation and antitumor activity of oximes, oxime ethers and a lactam Fulltext Access 29 Pages 2018
Synthesis and activity towards Alzheimer's disease in vitro: Tacrine, phenolic acid and ligustrazine hybrids Fulltext Access 29 Pages 2018
Replacement of Arg with Nle and modified D-Phe in the core sequence of MSHs, Ac-His-D-Phe-Arg-Trp-NH2, leads to hMC1R selectivity and pigmentation Fulltext Access 29 Pages 2018
Photophysical properties and photocytotoxicity of free and liposome-entrapped diazepinoporphyrazines on LNCaP cells under normoxic and hypoxic conditions Fulltext Access 29 Pages 2018
Design and biological evaluation of tetrahydro-β-carboline derivatives as highly potent histone deacetylase 6 (HDAC6) inhibitors Fulltext Access 29 Pages 2018
Functionalized spirooxindole-indolizine hybrids: Stereoselective green synthesis and evaluation of anti-inflammatory effect involving TNF-α and nitrite inhibition Fulltext Access 29 Pages 2018
Targeting prohibitin with small molecules to promote melanogenesis and apoptosis in melanoma cells Fulltext Access 29 Pages 2018
Mitochondria-targeting BODIPY-loaded micelles as novel class of photosensitizer for photodynamic therapy Fulltext Access 29 Pages 2018
Systems biology approach to study the role of miRNA in promoter targeting during megakaryopoiesis Fulltext Access 29 Pages 2018
EYA1 promotes tumor angiogenesis by activating the PI3K pathway in colorectal cancer Fulltext Access 29 Pages 2018
siRNA - Mediated LRP/LR knock-down reduces cellular viability of malignant melanoma cells through the activation of apoptotic caspases Fulltext Access 29 Pages 2018
LncRBA GSA5, up-regulated by ox-LDL, aggravates inflammatory response and MMP expression in THP-1 macrophages by acting like a sponge for miR-221 Fulltext Access 29 Pages 2018
Aldolase promotes the development of cardiac hypertrophy by targeting AMPK signaling Fulltext Access 29 Pages 2018
Exosomes derived from endothelial progenitor cells ameliorate acute lung injury by transferring miR-126 Fulltext Access 29 Pages 2018
Differentiation in stem/progenitor cells along fetal or adult hepatic stages requires transcriptional regulators independently of oscillations in microRNA expression Fulltext Access 29 Pages 2018
Ultra-high mass multimer analysis of protein-1a capping domains by a silicon nanomembrane detector Fulltext Access 29 Pages 2018
ATM inhibition induces synthetic lethality and enhances sensitivity of PTEN-deficient breast cancer cells to cisplatin Fulltext Access 29 Pages 2018
Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets Fulltext Access 29 Pages 2018
The reaction between GSNO and H2S: On the generation of NO, HNO and N2O Fulltext Access 29 Pages 2018
N-acetylcysteine protects against diabetic nephropathy through control of oxidative and nitrosative stress by recovery of nitric oxide in rats Fulltext Access 29 Pages 2018
Caspase-2 is required for skeletal muscle differentiation and myogenesis Fulltext Access 29 Pages 2018
Label-free discrimination analysis of de-differentiated vascular smooth muscle cells, mesenchymal stem cells and their vascular and osteogenic progeny using vibrational spectroscopy Fulltext Access 29 Pages 2018
Crosstalk between Nrf2 and YAP contributes to maintaining the antioxidant potential and chemoresistance in bladder cancer Fulltext Access 29 Pages 2018
S-glutathionylation exerts opposing roles in the regulation of STAT1 and STAT3 signaling in reactive microglia Fulltext Access 29 Pages 2018