An intronic single nucleotide polymorphism in the MUTYH gene is associated with increased risk for HCV-induced hepatocellular carcinoma Fulltext Access 31 Pages 2018
Rotavirus-encoded virus-like small RNA triggers autophagy by targeting IGF1R via the PI3K/Akt/mTOR pathway Fulltext Access 31 Pages 2018
Sex differences in the nitrate-nitrite-NO⢠pathway: Role of oral nitrate-reducing bacteria Fulltext Access 31 Pages 2018
Validation of reference genes for real-time PCR of cord blood mononuclear cells, differentiating endothelial progenitor cells, and mature endothelial cells Fulltext Access 31 Pages 2018
Use of LC-MS for the quantitative analysis of (poly)phenol metabolites does not necessarily yield accurate results: Implications for assessing existing data and conducting future research Fulltext Access 31 Pages 2018
microRNA-212-induced protection of the heart against myocardial infarction occurs via the interplay between AQP9 and PI3K/Akt signaling pathway Fulltext Access 31 Pages 2018
AIM2 is a potential therapeutic target in human renal carcinoma and suppresses its invasion and metastasis via enhancing autophagy induction Fulltext Access 31 Pages 2018
Human papillomavirus (HPV) oncoprotein E6 facilitates Calcineurin-Nuclear factor for activated T cells 2 (NFAT2) signaling to promote cellular proliferation in cervical cell carcinoma Fulltext Access 31 Pages 2018
MicroRNA-182 inhibits HCMV replication through activation of type I IFN response by targeting FOXO3 in neural cells Fulltext Access 31 Pages 2018
Electron transfer kinetics of the mitochondrial outer membrane protein mitoNEET Fulltext Access 31 Pages 2018
Melanoma-released exosomes directly activate the mitochondrial apoptotic pathway of CD4+ T cells through their microRNA cargo Fulltext Access 31 Pages 2018
1,25(OH)2D3 attenuates pulmonary arterial hypertension via microRNA-204 mediated Tgfbr2/Smad signaling Fulltext Access 31 Pages 2018
AF119895 regulates NXF3 expression to promote migration and invasion of hepatocellular carcinoma through an interaction with miR-6508-3p Fulltext Access 31 Pages 2018
Deregulation of Nrf2/ARE signaling pathway causes susceptibility of dystrophin-deficient myotubes to menadione-induced oxidative stress Fulltext Access 31 Pages 2018
Endoplasmic reticulum stress precedes oxidative stress in antibiotic-induced cholestasis and cytotoxicity in human hepatocytes Fulltext Access 31 Pages 2018
Caffeic acid and resveratrol ameliorate cellular damage in cell and Drosophila models of spinocerebellar ataxia type 3 through upregulation of Nrf2 pathway Fulltext Access 31 Pages 2018
The NOX1 isoform of NADPH oxidase is involved in dysfunction of liver sinusoids in nonalcoholic fatty liver disease Fulltext Access 31 Pages 2018
The IRF9-SIRT1-P53 axis is involved in the growth of human acute myeloid leukemia Fulltext Access 31 Pages 2018
The RNA binding protein tristetraprolin down-regulates autophagy in lung adenocarcinoma cells Fulltext Access 31 Pages 2018
HuR translocation to the cytoplasm of cancer cells in actin-independent manner Fulltext Access 32 Pages 2018
CDK8 regulates the angiogenesis of pancreatic cancer cells in part via the CDK8-β-catenin-KLF2 signal axis Fulltext Access 32 Pages 2018
A chimeric protein PTEN-L-p53 enters U251 cells to repress proliferation and invasion Fulltext Access 32 Pages 2018
The miR-200b/200a/429 cluster prevents metastasis and induces dormancy in a murine claudin-low mammary tumor cell line Fulltext Access 32 Pages 2018
Serelaxin inhibits differentiation and fibrotic behaviors of cardiac fibroblasts by suppressing ALK-5/Smad2/3 signaling pathway Fulltext Access 32 Pages 2018
Pseudo-phosphorylation at AT8 epitopes regulates the tau truncation at aspartate 421 Fulltext Access 32 Pages 2018
Salivary Glycopatterns as Potential Biomarkers for Screening of Early-Stage Breast Cancer Fulltext Access 32 Pages 2018
Triple negative breast cancer: Key role of Tumor-Associated Macrophages in regulating the activity of anti-PD-1/PD-L1 agents Fulltext Access 32 Pages 2018
Nitric oxide suppresses aluminum-induced programmed cell death in peanut (Arachis hypoganea L.) root tips by improving mitochondrial physiological properties Fulltext Access 32 Pages 2018
The lysine acetylome of the nematocidal bacterium Bacillus nematocida and impact of nematode on the acetylome Fulltext Access 32 Pages 2018
Modulating SIRT1 activity variously affects thymic lymphoma development in mice Fulltext Access 32 Pages 2018
Endothelial nitric oxide synthase enhancer AVE3085 reverses endothelial dysfunction induced by homocysteine in human internal mammary arteries Fulltext Access 32 Pages 2018
Activity of oxygen-versus sulfur-containing analogs of the Flex-Het anticancer agent SHetA2 Fulltext Access 32 Pages 2018
Arteriotomy site complication during transcatheter aortic valve replacement: Ipsilateral wire protection and bailout Fulltext Access 32 Pages 2018
Selenocysteine in mammalian thioredoxin reductase and application of ebselen as a therapeutic Fulltext Access 32 Pages 2018
Dynamic TSPO-PET for assessing early effects of cerebral hypoxia and resuscitation in new born pigs Fulltext Access 32 Pages 2018
Synthesis and evaluation of an N-[18F]fluorodeoxyglycosyl amino acid for PET imaging of tumor metabolism Fulltext Access 32 Pages 2018
Discovery of new 2, 5-disubstituted 1,3-selenazoles as selective human carbonic anhydrase IX inhibitors with potent anti-tumor activity Fulltext Access 32 Pages 2018
Design of PPAR-γ agonist based on algal metabolites and the endogenous ligand 15-deoxy-Î12, 14-prostaglandin J2 Fulltext Access 32 Pages 2018
CDNF induces the adaptive unfolded protein response and attenuates endoplasmic reticulum stress-induced cell death Fulltext Access 32 Pages 2018
Exosome-mediated miR-222 transferring: An insight into NF-κB-mediated breast cancer metastasis Fulltext Access 32 Pages 2018
Tight junction-associated protein GEF-H1 in the neighbours of dividing epithelial cells is essential for adaptation of cell-cell membrane during cytokinesis Fulltext Access 32 Pages 2018
Combination of DESI2 and endostatin gene therapy significantly improves antitumor efficacy by accumulating DNA lesions, inducing apoptosis and inhibiting angiogenesis Fulltext Access 32 Pages 2018
Upregulated SCUBE2 expression in breast cancer stem cells enhances triple negative breast cancer aggression through modulation of notch signaling and epithelial-to-mesenchymal transition Fulltext Access 32 Pages 2018
ANKRD9 is associated with tumor suppression as a substrate receptor subunit of ubiquitin ligase Fulltext Access 32 Pages 2018
Alkaline degradation of lyophilized DMSA prior to labeling with 99mTc: Identification and development of the degradation pathway by HPLC and MS Fulltext Access 32 Pages 2018
212Pb-labeled B7-H3-targeting antibody for pancreatic cancer therapy in mouse models Fulltext Access 32 Pages 2018
A new Drosophila model of Ubiquilin knockdown shows the effect of impaired proteostasis on locomotive and learning abilities Fulltext Access 32 Pages 2018
4TM-TRPM8 channels are new gatekeepers of the ER-mitochondria Ca2+ transfer Fulltext Access 32 Pages 2018
Conserved functions of Arabidopsis mitochondrial late-acting maturation factors in the trafficking of ironâsulfur clusters Fulltext Access 32 Pages 2018
Proteogenomic insights into uranium tolerance of a Chernobyl's Microbacterium bacterial isolate Fulltext Access 32 Pages 2018
TMT-based quantitative proteomics analysis reveals the response of tea plant (Camellia sinensis) to fluoride Fulltext Access 32 Pages 2018
Identification of candidate serum biomarkers of childhood-onset growth hormone deficiency using SWATH-MS and feature selection Fulltext Access 32 Pages 2018
Thiabendazole-based Rh(III) and Ir(III) biscyclometallated complexes with mitochondria-targeted anticancer activity and metal-sensitive photodynamic activity Fulltext Access 32 Pages 2018
Pyridine bioisosteres of potent GluN2B subunit containing NMDA receptor antagonists with benzo[7]annulene scaffold Fulltext Access 32 Pages 2018
NB 06: From a simple lysosomotropic aSMase inhibitor to tools for elucidating the role of lysosomes in signaling apoptosis and LPS-induced inflammation Fulltext Access 32 Pages 2018
Synthesis, molecular modeling and evaluation of α-glucosidase inhibition activity of 3,4-dihydroxy piperidines Fulltext Access 32 Pages 2018
Endoperoxide-8-aminoquinoline hybrids as dual-stage antimalarial agents with enhanced metabolic stability Fulltext Access 32 Pages 2018
Tetrahydroacridine derivatives with dichloronicotinic acid moiety as attractive, multipotent agents for Alzheimer's disease treatment Fulltext Access 32 Pages 2018
Nontoxic combretafuranone analogues with high in vitro antibacterial activity Fulltext Access 32 Pages 2018
Cordyceps sinensis: Anti-fibrotic and inflammatory effects of a cultured polysaccharide extract Fulltext Access 32 Pages 2018
Blockade of TREM-1 prevents vitreoretinal neovascularization in mice with oxygen-induced retinopathy Fulltext Access 32 Pages 2018
TRPM7 controls mesenchymal features of breast cancer cells by tensional regulation of SOX4 Fulltext Access 32 Pages 2018
Expression and therapeutic implications of cyclin-dependent kinase 4 (CDK4) in osteosarcoma Fulltext Access 32 Pages 2018
The search for novel diagnostic and prognostic biomarkers in cholangiocarcinoma Fulltext Access 32 Pages 2018
The scavenger activity of the human P2X7 receptor differs from P2X7 pore function by insensitivity to antagonists, genetic variation and sodium concentration: Relevance to inflammatory brain diseases Fulltext Access 32 Pages 2018
Oral pioglitazone ameliorates fructose-induced peripheral insulin resistance and hippocampal gliosis but not restores inhibited hippocampal adult neurogenesis Fulltext Access 32 Pages 2018
SIRT1 regulates inflammation response of macrophages in sepsis mediated by long noncoding RNA Fulltext Access 32 Pages 2018
Heparan sulfate potentiates leukocyte adhesion on cardiac fibroblast by enhancing Vcam-1 and Icam-1 expression Fulltext Access 32 Pages 2018
Discovery of N-hydroxy-3-alkoxybenzamides as direct acid sphingomyelinase inhibitors using a ligand-based pharmacophore model Fulltext Access 33 Pages 2018
Dual roles of different redox forms of complement factor H in protecting against age related macular degeneration Fulltext Access 33 Pages 2018
Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways Fulltext Access 33 Pages 2018
ILT4 functions as a potential checkpoint molecule for tumor immunotherapy Fulltext Access 33 Pages 2018
Hedgehog pathway inhibitors of the acylthiourea and acylguanidine class show antitumor activity on colon cancer in vitro and in vivo Fulltext Access 33 Pages 2018
Apoptosis-Inducing Factor (AIF) in Physiology and Disease: The Tale of a Repented Natural Born Killer Fulltext Access 33 Pages 2018
Total synthesis of acylphloroglucinols and their antibacterial activities against clinical isolates of multi-drug resistant (MDR) and methicillin-resistant strains of Staphylococcus aureus Fulltext Access 33 Pages 2018
Homopiperazine-rhodamine B adducts of triterpenoic acids are strong mitocans Fulltext Access 33 Pages 2018
Argirein alleviates vascular endothelial insulin resistance through suppressing the activation of Nox4-dependent O2- production in diabetic rats Fulltext Access 33 Pages 2018
Oxidative stress induced by prenatal LPS leads to endothelial dysfunction and renal haemodynamic changes through angiotensin II/NADPH oxidase pathway: Prevention by early treatment with α-tocopherol Fulltext Access 33 Pages 2018
Epigenetic Changes in the CRH Gene are Related to Severity of Suicide Attempt and a General Psychiatric Risk Score in Adolescents Fulltext Access 33 Pages 2018
Metallomics for Alzheimer's disease treatment: Use of new generation of chelators combining metal-cation binding and transport properties Fulltext Access 33 Pages 2018
The SGK1 inhibitor EMD638683, prevents Angiotensin II-induced cardiac inflammation and fibrosis by blocking NLRP3 inflammasome activation Fulltext Access 33 Pages 2018
Design and synthesis of novel pyrrolo[2,3-a]carbazoles: 7-Chloro-2-oxo-3a-(2â²-oxo-2â²,3â²-dihydro-1â²H-indol-3â²-yl)-2,3,3a,4,5,10-hexahydro-pyrrolo[3,2-a]carbazole-1-carbonitrile as an efficient anticancer agent Fulltext Access 33 Pages 2018
PVT1 regulates the malignant behaviors of human glioma cells by targeting miR-190a-5p and miR-488-3p Fulltext Access 33 Pages 2018
More to NAD+ than meets the eye: A regulator of metabolic pools and gene expression in Arabidopsis Fulltext Access 33 Pages 2018
Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic acid Fulltext Access 33 Pages 2018
Identification of novel N1-(2-aryl-1, 3-thiazolidin-4-one)-N3-aryl ureas showing potent multi-tyrosine kinase inhibitory activities Fulltext Access 33 Pages 2018
Evaluation of 4-oxo-quinoline-based CB2 PET radioligands in R6/2 chorea huntington mouse model and human ALS spinal cord tissue Fulltext Access 33 Pages 2018
Novel inhibitors of the rRNA ErmC' methyltransferase to block resistance to macrolides, lincosamides, streptogramine B antibiotics Fulltext Access 33 Pages 2018
Adipose tissue derived-factors impaired pancreatic β-cell function in diabetes Fulltext Access 33 Pages 2018
Hepatic oxidative stress in pigmented P23H rhodopsin transgenic rats with progressive retinal degeneration Fulltext Access 33 Pages 2018
The newly established bovine endometrial gland cell line (BEGC) forms gland acini in vitro and is only IFNÏ-responsive (MAPK42/44 activation) after E2 and P4-pre-incubation Fulltext Access 33 Pages 2018
Glycine Transporter-1 and glycine receptor mediate the antioxidant effect of glycine in diabetic rat islets and INS-1 cells Fulltext Access 33 Pages 2018
Metformin overcomes high glucose-induced insulin resistance of podocytes by pleiotropic effects on SIRT1 and AMPK Fulltext Access 33 Pages 2018
Functional role of a long non-coding RNA LIFR-AS1/miR-29a/TNFAIP3 axis in colorectal cancer resistance to pohotodynamic therapy Fulltext Access 33 Pages 2018