The suppression effect of dendritic cells maturation by adipose-derived stem cells through TGF-β1 related pathway Fulltext Access 33 Pages 2018
Alteration in microRNA-25 expression regulate cardiac function via renin secretion Fulltext Access 33 Pages 2018
Homo- and heteroleptic Pt(II) complexes of ONN donor hydrazone and 4-picoline: A synthetic, structural and detailed mechanistic anticancer investigation Fulltext Access 33 Pages 2018
Identification of an oxime-containing C-glucosylarene as a potential inhibitor of sodium-dependent glucose co-transporter 2 Fulltext Access 33 Pages 2018
Structural and biological characterization of new hybrid drugs joining an HDAC inhibitor to different NO-donors Fulltext Access 33 Pages 2018
RHBDF1 regulates APC-mediated stimulation of the epithelial-to-mesenchymal transition and proliferation of colorectal cancer cells in part via the Wnt/β-catenin signalling pathway Fulltext Access 33 Pages 2018
The development of methods for primary mast cells in vitro and ex vivo: An historical review Fulltext Access 33 Pages 2018
Overexpression of CTNNB1: Clinical implication in Chinese de novo acute myeloid leukemia Fulltext Access 33 Pages 2018
Combined detection of insulin-like growth factor-binding protein 7 promoter methylation improves the diagnostic efficacy of AFP in hepatitis B virus-associated hepatocellular carcinoma Fulltext Access 33 Pages 2018
Reduced blood pressure responsiveness to skeletal muscle metaboreflex activation in older adults following inorganic nitrate supplementation Fulltext Access 33 Pages 2018
Disruption of adherens junction and alterations in YAP-related proliferation behavior as part of the underlying cell transformation process of alcohol-induced oral carcinogenesis Fulltext Access 33 Pages 2018
[99mTc]duramycin, a potential molecular probe for early prediction of tumor response after chemotherapy Fulltext Access 33 Pages 2018
Synthesis of scutellarein derivatives with antiproliferative activity and selectivity through the intrinsic pathway Fulltext Access 33 Pages 2018
AUF1 modulates TGF-β signal in renal tubular epithelial cells via post-transcriptional regulation of Nedd4L expression Fulltext Access 33 Pages 2018
Synthesis of 1,2,3-triazole linked 4(3H)-Quinazolinones as potent antibacterial agents against multidrug-resistant Staphylococcus aureus Fulltext Access 33 Pages 2018
VPS28, an ESCRT-I protein, regulates mitotic spindle organization via Gβγ, EG5 and TPX2 Fulltext Access 33 Pages 2018
Design, synthesis, and biological evaluations of phenylpropiolic acid derivatives as novel GPR40 agonists Fulltext Access 33 Pages 2018
l,8-Naphthalimide based DNA intercalators and anticancer agents. AÂ systematic review from 2007 to 2017 Fulltext Access 33 Pages 2018
Synthesis, molecular docking and inhibition studies of novel 3-N-aryl substituted-2-heteroarylchromones targeting microtubule affinity regulating kinase 4 inhibitors Fulltext Access 33 Pages 2018
2ʹ-Aryl and 4ʹ-arylidene substituted pyrazolones: As potential α-amylase inhibitors Fulltext Access 33 Pages 2018
Correlates of Protection Against SIVmac251 Infection in Rhesus Macaques Immunized With Chimpanzee-Derived Adenovirus Vectors Fulltext Access 34 Pages 2018
Peroxiredoxin 2 deficiency accelerates age-related ovarian failure through the reactive oxygen species-mediated JNK pathway in mice Fulltext Access 34 Pages 2018
Cross-pathway control gene CPC1/GCN4 coordinates with histone acetyltransferase GCN5 to regulate catalase-3 expression under oxidative stress in Neurospora crassa Fulltext Access 34 Pages 2018
A novel signal sequence negative multimeric glycosomal protein required for cell cycle progression of Leishmania donovani parasites Fulltext Access 34 Pages 2018
Complement 5a stimulates macrophage polarization and contributes to tumor metastases of colon cancer Fulltext Access 34 Pages 2018
Wnt11 alters integrin and cadherin expression by ovarian cancer spheroids and inhibits tumorigenesis and metastasis Fulltext Access 34 Pages 2018
Distinct hypoxic regulation of preadipocyte factor-1 (Pref-1) in preadipocytes and mature adipocytes Fulltext Access 34 Pages 2018
MiR-125b-5p is involved in oxygen and glucose deprivation injury in PC-12 cells via CBS/H2S pathway Fulltext Access 34 Pages 2018
Establishment of a method for in-vivo SPECT/CT imaging analysis of 111In-labeled exendin-4 pancreatic uptake in mice without the need for nephrectomy or a secondary probe Fulltext Access 34 Pages 2018
α-Actinin-4 confers radioresistance coupled invasiveness in breast cancer cells through AKT pathway Fulltext Access 34 Pages 2018
Crucial role of HO-1/IRF4-dependent apoptosis induced by panobinostat and lenalidomide in multiple myeloma Fulltext Access 34 Pages 2018
PDGF-mediated PI3K/AKT/β-catenin signaling regulates gap junctions in corpus cavernosum smooth muscle cells Fulltext Access 34 Pages 2018
NLRP3 inflammasome inhibition attenuates silica-induced epithelial to mesenchymal transition (EMT) in human bronchial epithelial cells Fulltext Access 34 Pages 2018
Novel spiroindoline HDAC inhibitors: Synthesis, molecular modelling and biological studies Fulltext Access 34 Pages 2018
Impact of structural alterations on the radiopharmacological profile of 18F-labeled pyrimidines as cyclooxygenase-2 (COX-2) imaging agents Fulltext Access 34 Pages 2018
Time-dependent transcriptional response of GOT1 human small intestine neuroendocrine tumor after 177Lu[Lu]-octreotate therapy Fulltext Access 34 Pages 2018
Maternal high estradiol exposure alters CDKN1C and IGF2 expression in human placenta Fulltext Access 34 Pages 2018
Proteomic identification of altered protein O-GlcNAcylation in a triple transgenic mouse model of Alzheimer's disease Fulltext Access 34 Pages 2018
Fucosyltransferase 2 induced epithelial-mesenchymal transition via TGF-β/Smad signaling pathway in lung adenocarcinaoma Fulltext Access 34 Pages 2018
Overexpression of CXCR4 synergizes with LL-37 in the metastasis of breast cancer cells Fulltext Access 34 Pages 2018
Pathophysiological consequences of isoform-specific IP3 receptor mutations Fulltext Access 34 Pages 2018
Intracellular calcium dysregulation in autism spectrum disorder: An analysis of converging organelle signaling pathways Fulltext Access 34 Pages 2018
IL-23 production of liver inflammatory macrophages to damaged hepatocytes promotes hepatocellular carcinoma development after chronic hepatitis B virus infection Fulltext Access 34 Pages 2018
TRF1 as a major contributor for telomeres' shortening in the context of obesity Fulltext Access 34 Pages 2018
Discovery of furyl/thienyl β-carboline derivatives as potent and selective PDE5 inhibitors with excellent vasorelaxant effect Fulltext Access 34 Pages 2018
Redox-active trace metal-induced release of high mobility group box 1(HMGB1) and inflammatory cytokines in fibroblast-like synovial cells is Toll-like receptor 4 (TLR4) dependent Fulltext Access 34 Pages 2018
Synthesis and evaluation of novel coumarin-oxime ethers as potential anti-tubercular agents: Their DNA cleavage ability and BSA interaction study Fulltext Access 34 Pages 2018
Synthesis and antiproliferative activity of pyrrolo[2,3-b]pyridine derivatives bearing the 1,8-naphthyridin-2-one moiety Fulltext Access 34 Pages 2018
2-Substituted 7-trifluoromethyl-thiadiazolopyrimidones as alkaline phosphatase inhibitors. Synthesis, structure activity relationship and molecular docking study Fulltext Access 34 Pages 2018
A highly potent CDK4/6 inhibitor was rationally designed to overcome blood brain barrier in gliobastoma therapy Fulltext Access 34 Pages 2018
Design, synthesis and biological evaluation of novel 4-aminoquinazolines as dual target inhibitors of EGFR-PI3Kα Fulltext Access 34 Pages 2018
A certain role of SOD/CAT imbalance in pathogenesis of autism spectrum disorders Fulltext Access 34 Pages 2018
Unexplored antifungal activity of linear battacin lipopeptides against planktonic and mature biofilms of C. albicans Fulltext Access 34 Pages 2018
The 4-N-acyl and 4-N-alkyl gemcitabine analogues with silicon-fluoride-acceptor: Application to 18F-Radiolabeling Fulltext Access 34 Pages 2018
Synthesis of N-(1-(6-acetamido-5-phenylpyrimidin-4-yl) piperidin-3-yl) amide derivatives as potential inhibitors for mitotic kinesin spindle protein Fulltext Access 34 Pages 2018
Design, synthesis and identification of silicon-containing HCV NS5A inhibitors with pan-genotype activity Fulltext Access 34 Pages 2018
Design, synthesis, and biological evaluation of novel amide and hydrazide based thioether analogs targeting Histone deacteylase (HDAC) enzymes Fulltext Access 34 Pages 2018
Synthesis of C3-Neoglycosides of digoxigenin and their anticancer activities Fulltext Access 34 Pages 2018
Structure-activity relationships of 2, 4-disubstituted pyrimidines as dual ERα/VEGFR-2 ligands with anti-breast cancer activity Fulltext Access 34 Pages 2018
Discovery of 6-chloro-2-(propylthio)-8,9-dihydro-7H-purines containing a carboxamide moiety as potential selective anti-lung cancer agents Fulltext Access 34 Pages 2018
A novel NAE/UAE dual inhibitor LP0040 blocks neddylation and ubiquitination leading to growth inhibition and apoptosis of cancer cells Fulltext Access 34 Pages 2018
Structure-based design of novel quinoxaline-2-carboxylic acids and analogues as Pim-1 inhibitors Fulltext Access 34 Pages 2018
Design, synthesis, antiproliferative activity and docking studies of quinazoline derivatives bearing 2,3-dihydro-indole or 1,2,3,4-tetrahydroquinoline as potential EGFR inhibitors Fulltext Access 34 Pages 2018
Synergistic inhibition of the Hedgehog pathway by newly designed Smo and Gli antagonists bearing the isoflavone scaffold Fulltext Access 34 Pages 2018
Rational design of dimeric lipidated Xenopus glucagon-like peptide 1 analogues as long-acting antihyperglycaemic agents Fulltext Access 34 Pages 2018
8-Aryl-6-chloro-3-nitro-2-(phenylsulfonylmethyl)imidazo[1,2-a]pyridines as potent antitrypanosomatid molecules bioactivated by type 1 nitroreductases Fulltext Access 34 Pages 2018
Sulfiredoxin-1 enhances cardiac progenitor cell survival against oxidative stress via the upregulation of the ERK/NRF2 signal pathway Fulltext Access 34 Pages 2018
2-Arylbenzofurans from Artocarpus lakoocha and methyl ether analogs with potent cholinesterase inhibitory activity Fulltext Access 34 Pages 2018
The U2AF homology motif kinase 1 (UHMK1) is upregulated upon hematopoietic cell differentiation Fulltext Access 34 Pages 2018
HER4 promotes cell survival and chemoresistance in osteosarcoma via interaction with NDRG1 Fulltext Access 34 Pages 2018
Endothelial cells cope with hypoxia-induced depletion of ATP via activation of cellular purine turnover and phosphotransfer networks Fulltext Access 34 Pages 2018
Induction of REDD1 via AP-1 prevents oxidative stress-mediated injury in hepatocytes Fulltext Access 34 Pages 2018
Fluorescent organometallic rhodium(I) and ruthenium(II) metallodrugs with 4-ethylthio-1,8-naphthalimide ligands: Antiproliferative effects, cellular uptake and DNA-interaction Fulltext Access 35 Pages 2018
Fragment-growing guided design of Keap1-Nrf2 protein-protein interaction inhibitors for targeting myocarditis Fulltext Access 35 Pages 2018
IKK1/2 protect human cells from TNF-mediated RIPK1-dependent apoptosis in an NF-κB-independent manner Fulltext Access 35 Pages 2018
Structure-activity relationships of anticancer ruthenium(II) complexes with substituted hydroxyquinolines Fulltext Access 35 Pages 2018
Synthesis, characterization and biological evaluation of tertiary sulfonamide derivatives of pyridyl-indole based heteroaryl chalcone as potential carbonic anhydrase IX inhibitors and anticancer agents Fulltext Access 35 Pages 2018
Enhanced mitochondrial DNA repair of the common disease-associated variant, Ser326Cys, of hOGG1 through small molecule intervention Fulltext Access 35 Pages 2018
IgE induces hypotension in asthma mice by down-regulating vascular NCX1 expression through activating MiR-212-5p Fulltext Access 35 Pages 2018
A heart-enriched antisense long non-coding RNA regulates the balance between cardiac and skeletal muscle triadin Fulltext Access 35 Pages 2018
A novel S-nitrosocaptopril monohydrate for pulmonary arterial hypertension: H2O and -SNO intermolecular stabilization chemistry Fulltext Access 35 Pages 2018
Design, synthesis and bioevaluation of 1,2,3,9-tetrahydropyrrolo[2,1-b]quinazoline-1-carboxylic acid derivatives as potent neuroprotective agents Fulltext Access 35 Pages 2018
[18F]Diphenyl sulfide derivatives for imaging serotonin transporter (SERT) in the brain Fulltext Access 35 Pages 2018
Inhibition of EGFR attenuates fibrosis and stellate cell activation in diet-induced model of nonalcoholic fatty liver disease Fulltext Access 35 Pages 2018
2-Aryl benzimidazoles: Synthesis, In vitro α-amylase inhibitory activity, and molecular docking study Fulltext Access 35 Pages 2018
Human U3 protein14a is a novel type ubiquitin ligase that binds RB and promotes RB degradation depending on a leucine-rich region Fulltext Access 35 Pages 2018
n-3 Fatty acids combined with flavan-3-ols prevent steatosis and liver injury in a murine model of NAFLD Fulltext Access 35 Pages 2018
TRAIL protects against endothelial dysfunction in vivo and inhibits angiotensin-II-induced oxidative stress in vascular endothelial cells in vitro Fulltext Access 35 Pages 2018
New perspectives for pharmacological chaperoning treatment in methylmalonic aciduria cblB type Fulltext Access 35 Pages 2018
Activation of the EPOR-β common receptor complex by cibinetide ameliorates impaired wound healing in mice with genetic diabetes Fulltext Access 35 Pages 2018
Pigment epithelium derived factor regulates human Sost/Sclerostin and other osteocyte gene expression via the receptor and induction of Erk/GSK-3beta/beta-catenin signaling Fulltext Access 35 Pages 2018
Simvastatin blocks soluble SSAO/VAP-1 release in experimental models of cerebral ischemia: Possible benefits for stroke-induced inflammation control Fulltext Access 35 Pages 2018
Extracellular histones activate autophagy and apoptosis via mTOR signaling in human endothelial cells Fulltext Access 35 Pages 2018
Application of silica coated magnetite nanoparticles modified with Cu(I)-neocuproine as nanosorbent to simultaneous separation-preconcentration of trace amounts of nitrate and nitrite Fulltext Access 35 Pages 2018
miR-146a regulates inflammatory cytokine production in Porphyromonas gingivalis lipopolysaccharide-stimulated B cells by targeting IRAK1 but not TRAF6 Fulltext Access 35 Pages 2018
C-terminal oligomerization of podocin mediates interallelic interactions Fulltext Access 35 Pages 2018
Influence of transport line material on the molar activity of cyclotron produced [18F]fluoride Fulltext Access 35 Pages 2018
FGF binding proteins (FGFBPs): Modulators of FGF signaling in the developing, adult, and stressed nervous system Fulltext Access 35 Pages 2018