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Daneshyari Molecular Medicine Journas Latest Articles

Molecular Medicine Research Articles

Differential biotin labelling of the cell envelope proteins in lipopolysaccharidic diderm bacteria: Exploring the proteosurfaceome of Escherichia coli using sulfo-NHS-SS-biotin and sulfo-NHS-PEG4-bismannose-SS-biotin
Fulltext Access 37 Pages 2018
ALK3 undergoes ligand-independent homodimerization and BMP-induced heterodimerization with ALK2
Fulltext Access 37 Pages 2018
Mutant p53 prevents GAPDH nuclear translocation in pancreatic cancer cells favoring glycolysis and 2-deoxyglucose sensitivity
Fulltext Access 37 Pages 2018
Selenium, selenoprotein P, and Alzheimer's disease: is there a link?
Fulltext Access 37 Pages 2018
Adult onset hereditary hemochromatosis is associated with a novel recurrent Hemojuvelin (HJV) gene mutation in north Indians
Fulltext Access 37 Pages 2018
Pax2 is essential for proliferation and osteogenic differentiation of mouse mesenchymal stem cells via Runx2
Fulltext Access 37 Pages 2018
Non-tumor adjacent tissue of advanced stage from CRC shows activated antioxidant response
Fulltext Access 37 Pages 2018
Sirtuin 5 overexpression attenuates glucolipotoxicity-induced pancreatic β cells apoptosis and dysfunction
Fulltext Access 37 Pages 2018
Computed tomography (CT) assessment of the membranous septal anatomy prior to transcatheter aortic valve replacement (TAVR) with the balloon-expandable SAPIEN 3 valve
Fulltext Access 37 Pages 2018
Caveolae-mediated effects of TNF-α on human skeletal muscle cells
Fulltext Access 37 Pages 2018
Neuron-specific knockdown of Drosophila PDHB induces reduction of lifespan, deficient locomotive ability, abnormal morphology of motor neuron terminals and photoreceptor axon targeting
Fulltext Access 37 Pages 2018
Cigarette smoke constituents cause endothelial nitric oxide synthase dysfunction and uncoupling due to depletion of tetrahydrobiopterin with degradation of GTP cyclohydrolase
Fulltext Access 37 Pages 2018
Post-translational modifications of eNOS augment nitric oxide availability and facilitates hypoxia adaptation in Ladakhi women
Fulltext Access 37 Pages 2018
RACK1/TRAF2 regulation of modulator of apoptosis-1 (MOAP-1)
Fulltext Access 37 Pages 2018
C1QTNF1 attenuates angiotensin II-induced cardiac hypertrophy via activation of the AMPKa pathway
Fulltext Access 37 Pages 2018
Anagliptin inhibits neointimal hyperplasia after balloon injury via endothelial cell-specific modulation of SOD-1/RhoA/JNK signaling in the arterial wall
Fulltext Access 37 Pages 2018
Identification of ethanol tolerant outer membrane proteome reveals OmpC-dependent mechanism in a manner of EnvZ/OmpR regulation in Escherichia coli
Fulltext Access 37 Pages 2018
β-Arrestin2 directly or through GRK2 inhibits PKCβII activation in a ubiquitination-dependent manner
Fulltext Access 38 Pages 2018
An electrochemical approach for removal of radionuclidic contaminants of Eu from 153Sm for effective use in metastatic bone pain palliation
Fulltext Access 38 Pages 2018
Alanine and glycine conjugates of (2S,4R)-4-[18F]fluoroglutamine for tumor imaging
Fulltext Access 38 Pages 2018
Production of bioactive recombinant human Eb-peptide of pro-IGF-I and identification of binding components from the plasma membrane of human breast cancer cells (MDA-MB-231)
Fulltext Access 38 Pages 2018
Neutrophil CD16b crosslinking induces lipid raft-mediated activation of SHP-2 and affects cytokine expression and retarded neutrophil apoptosis
Fulltext Access 38 Pages 2018
Targeting ALDH2 with disulfiram/copper reverses the resistance of cancer cells to microtubule inhibitors
Fulltext Access 38 Pages 2018
4-(Phenoxy) and 4-(benzyloxy)benzamides as potent and selective inhibitors of mono-ADP-ribosyltransferase PARP10/ARTD10
Fulltext Access 38 Pages 2018
Relation of nNOS isoforms to mitochondrial density and PGC-1alpha expression in striated muscles of mice
Fulltext Access 38 Pages 2018
New aziridine-based inhibitors of cathepsin L-like cysteine proteases with selectivity for the Leishmania cysteine protease LmCPB2.8
Fulltext Access 38 Pages 2018
Calpeptin attenuates cigarette smoke-induced pulmonary inflammation via suppressing calpain/IκBα signaling in mice and BEAS-2B cells
Fulltext Access 38 Pages 2018
Nontypeable Haemophilus influenzae DNA stimulates type I interferon expression via STING signaling pathway
Fulltext Access 38 Pages 2018
Rab7a modulates ER stress and ER morphology
Fulltext Access 38 Pages 2018
Different phosphorylation patterns regulate α1D-adrenoceptor signaling and desensitization
Fulltext Access 38 Pages 2018
IP3R3 silencing induced actin cytoskeletal reorganization through ARHGAP18/RhoA/mDia1/FAK pathway in breast cancer cell lines
Fulltext Access 38 Pages 2018
TGF-β and BMP signals regulate insect diapause through Smad1-POU-TFAM pathway
Fulltext Access 38 Pages 2018
Honokiol alleviates the degeneration of intervertebral disc via suppressing the activation of TXNIP-NLRP3 inflammasome signal pathway
Fulltext Access 38 Pages 2018
Discovery of novel β-carboline/acylhydrazone hybrids as potent antitumor agents and overcome drug resistance
Fulltext Access 38 Pages 2018
Missense mutation of SPAST protein (I344K) results in loss of ATPase activity and prolonged the half-life, implicated in autosomal dominant hereditary spastic paraplegia
Fulltext Access 38 Pages 2018
Design, synthesis, docking studies and biological screening of 2-thiazolyl substituted -2,3-dihydro-1H-naphtho[1,2-e][1,3]oxazines as potent HIV-1 reverse transcriptase inhibitors
Fulltext Access 38 Pages 2018
Use of ribosomal proteins as biomarkers for identification of Flavobacterium psychrophilum by MALDI-TOF mass spectrometry
Fulltext Access 38 Pages 2018
Cytotoxicity of Clostridium perfringens enterotoxin depends on the conditions of claudin-4 in ovarian carcinoma cells
Fulltext Access 38 Pages 2018
Pd(II) and Pt(II) saccharinate complexes of bis(diphenylphosphino)propane/butane: Synthesis, structure, antiproliferative activity and mechanism of action
Fulltext Access 38 Pages 2018
Promastigote parasites cultured from the lesions of patients with mucosal leishmaniasis are more resistant to oxidative stress than promastigotes from a cutaneous lesion
Fulltext Access 38 Pages 2018
NADPH oxidase, oxidative stress and fibrosis in systemic sclerosis
Fulltext Access 38 Pages 2018
Calcium signaling and the lytic cycle of the Apicomplexan parasite Toxoplasma gondii
Fulltext Access 38 Pages 2018
Hippo, Drosophila MST, is a novel modifier of motor neuron degeneration induced by knockdown of Caz, Drosophila FUS
Fulltext Access 38 Pages 2018
Proteomic analysis reveals the important roles of alpha-5-collagen and ATP5β during skin ulceration syndrome progression of sea cucumber Apostichopus japonicus
Fulltext Access 38 Pages 2018
A comprehensive review on xanthone derivatives as α-glucosidase inhibitors
Fulltext Access 38 Pages 2018
Boronic ester-linked macrocyclic lipopeptides as serine protease inhibitors targeting Escherichia coli type I signal peptidase
Fulltext Access 38 Pages 2018
Tub and β-catenin play a key role in insulin and leptin resistance-induced pancreatic beta-cell differentiation
Fulltext Access 38 Pages 2018
Proteome response of dental pulp cells to exogenous FGF8
Fulltext Access 38 Pages 2018
Activation of the monocytic α7 nicotinic acetylcholine receptor modulates oxidative stress and inflammation-associated development of coronary artery spasm via a p38 MAP-kinase signaling-dependent pathway
Fulltext Access 38 Pages 2018
Activation of bradykinin B2 receptor induced the inflammatory responses of cytosolic phospholipase A2 after the early traumatic brain injury
Fulltext Access 38 Pages 2018
YAP promotes breast cancer metastasis by repressing growth differentiation factor-15
Fulltext Access 38 Pages 2018
Histone methyltransferase G9a modulates hepatic insulin signaling via regulating HMGA1
Fulltext Access 38 Pages 2018
Discovery of novel HSP90 inhibitors that induced apoptosis and impaired autophagic flux in A549 lung cancer cells
Fulltext Access 38 Pages 2018
Inhibitor of the human telomerase reverse trancriptase (hTERT) gene promoter induces cell apoptosis via a mitochondrial-dependent pathway
Fulltext Access 38 Pages 2018
Autophagy and oxidative stress in non-communicable diseases: A matter of the inflammatory state?
Fulltext Access 38 Pages 2018
5-Bromo-oxoisoaporphine platinum(II) complexes exhibit tumor cell cytotoxcicity via inhibition of telomerase activity and disruption of c-myc G-quadruplex DNA and mitochondrial functions
Fulltext Access 38 Pages 2018
Apigenin C-glycosides of Microcos paniculata protects lipopolysaccharide induced apoptosis and inflammation in acute lung injury through TLR4 signaling pathway
Fulltext Access 38 Pages 2018
New insights in Au-NHCs complexes as anticancer agents
Fulltext Access 38 Pages 2018
Dysregulated Txnip-ROS-Wnt axis contributes to the impaired ischemic heart repair in diabetic mice
Fulltext Access 39 Pages 2018
Alkoxyphenylthiazoles with broad-spectrum activity against multidrug-resistant gram-positive bacterial pathogens
Fulltext Access 39 Pages 2018
Hepatitis B virus upregulates host microRNAs that target apoptosis-regulatory genes in an in vitro cell model
Fulltext Access 39 Pages 2018
Novel ruthenium methylcyclopentadienyl complex bearing a bipyridine perfluorinated ligand shows strong activity towards colorectal cancer cells
Fulltext Access 39 Pages 2018
Biological activity of dihydropyrimidinone (DHPM) derivatives: A systematic review
Fulltext Access 39 Pages 2018
How to use and integrate bioinformatics tools to compare proteomic data from distinct conditions? A tutorial using the pathological similarities between Aortic Valve Stenosis and Coronary Artery Disease as a case-study
Fulltext Access 39 Pages 2018
TRPM2 mediates mitochondria-dependent apoptosis of melanocytes under oxidative stress
Fulltext Access 39 Pages 2018
ARID1A mutant ovarian clear cell carcinoma: A clear target for synthetic lethal strategies
Fulltext Access 39 Pages 2018
Hepatocyte-specific deletion of LASS2 protects against diet-induced hepatic steatosis and insulin resistance
Fulltext Access 39 Pages 2018
Hydroxymethyl bioisosteres of phenolic GluN2B-selective NMDA receptor antagonists: Design, synthesis and pharmacological evaluation
Fulltext Access 39 Pages 2018
Design, synthesis, and structure-activity-relationship of a novel series of CXCR4 antagonists
Fulltext Access 39 Pages 2018
Novel hybrids of brefeldin A and nitrogen mustards with improved antiproliferative selectivity: Design, synthesis and antitumor biological evaluation
Fulltext Access 39 Pages 2018
Proteomic comparison of three clinical diarrhoeagenic drug-resistant Escherichia coli isolates grown on CHROMagar™STEC media
Fulltext Access 39 Pages 2018
The concept of hybrid molecules of tacrine and benzyl quinolone carboxylic acid (BQCA) as multifunctional agents for Alzheimer's disease
Fulltext Access 39 Pages 2018
LAURDAN fluorescence and phasor plots reveal the effects of a H2O2 bolus in NIH-3T3 fibroblast membranes dynamics and hydration
Fulltext Access 39 Pages 2018
Synthesis of gold(I) phosphine complexes containing the 2-BrC6F4PPh2 ligand: Evaluation of anticancer activity in 2D and 3D spheroidal models of HeLa cancer cells
Fulltext Access 39 Pages 2018
Experimental design and data-analysis in label-free quantitative LC/MS proteomics: A tutorial with MSqRob
Fulltext Access 39 Pages 2018
Design, synthesis and anticancer evaluation of novel spirobenzo[h]chromene and spirochromane derivatives with dual EGFR and B-RAF inhibitory activities
Fulltext Access 39 Pages 2018
Synthesis and biological evaluation of novel Jiyuan Oridonin A-1,2,3-triazole-azole derivatives as antiproliferative agents
Fulltext Access 39 Pages 2018
Mixed-ligand Cu(II) hydrazone complexes designed to enhance anticancer activity
Fulltext Access 39 Pages 2018
Lysosomal N-acetyltransferase interacts with ALIX and is detected in extracellular vesicles
Fulltext Access 39 Pages 2018
Reduction of nitrosative stress by methane: Neuroprotection through xanthine oxidoreductase inhibition in a rat model of mesenteric ischemia-reperfusion
Fulltext Access 39 Pages 2018
Facile synthesis of vanillin-based novel bischalcones identifies one that induces apoptosis and displays synergy with Artemisinin in killing chloroquine resistant Plasmodium falciparum
Fulltext Access 39 Pages 2018
Nrf2 inhibits oxaliplatin-induced peripheral neuropathy via protection of mitochondrial function
Fulltext Access 39 Pages 2018
New 6-amino-pyrido[2,3-d]pyrimidine-2,4-diones as novel agents to treat type 2 diabetes: A simple and efficient synthesis, α-glucosidase inhibition, molecular modeling and kinetic study
Fulltext Access 39 Pages 2018
Design, synthesis and pharmacological evaluation of ALK and Hsp90 dual inhibitors bearing resorcinol and 2,4-diaminopyrimidine motifs
Fulltext Access 39 Pages 2018
ROS modifiers and NOX4 affect the expression of the survivin-associated radio-adaptive response
Fulltext Access 39 Pages 2018
Soft drug-resistant ovarian cancer cells migrate via two distinct mechanisms utilizing myosin II-based contractility
Fulltext Access 39 Pages 2018
The uL10 protein, a component of the ribosomal P-stalk, is released from the ribosome in nucleolar stress
Fulltext Access 39 Pages 2018
Cannabidiol induced apoptosis in human monocytes through mitochondrial permeability transition pore-mediated ROS production
Fulltext Access 39 Pages 2018
Development of a novel monoclonal antibody against 4-hydroxy-2E,6Z-dodecadienal (4-HDDE)-protein adducts: Immunochemical application in quantitative and qualitative analyses of lipid peroxidation in vitro and ex vivo
Fulltext Access 39 Pages 2018
Cannabidiol restores differentiation capacity of LPS exposed adipose tissue mesenchymal stromal cells
Fulltext Access 39 Pages 2018
Interactions between monomeric CCTδ and p150Glued: A novel function for CCTδ at the cell periphery distinct from the protein folding activity of the molecular chaperone CCT
Fulltext Access 39 Pages 2018
RalGPS2 is involved in tunneling nanotubes formation in 5637 bladder cancer cells
Fulltext Access 39 Pages 2018
UVA-induced carbon-centred radicals in lightly pigmented cells detected using ESR spectroscopy
Fulltext Access 39 Pages 2018
Utrophin up-regulation by artificial transcription factors induces muscle rescue and impacts the neuromuscular junction in mdx mice
Fulltext Access 39 Pages 2018
Herpud1 impacts insulin-dependent glucose uptake in skeletal muscle cells by controlling the Ca2+-calcineurin-Akt axis
Fulltext Access 39 Pages 2018
Re(CO)3([18F]FEDA), a novel 18F PET renal tracer: Radiosynthesis and preclinical evaluation
Fulltext Access 39 Pages 2018
Nesfatin-1 functions as a switch for phenotype transformation and proliferation of VSMCs in hypertensive vascular remodeling
Fulltext Access 39 Pages 2018
Transradial versus Transfemoral access in patients undergoing peripheral artery angioplasty/stenting: A meta-analysis
Fulltext Access 39 Pages 2018
Epigenetic dysregulation of ZEB1 is involved in LMO2-promoted T-cell acute lymphoblastic leukaemia leukaemogenesis
Fulltext Access 39 Pages 2018
Pharmacomodulation on Gold-NHC complexes for anticancer applications - is lipophilicity the key point?
Fulltext Access 39 Pages 2018
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