Antifibrotic role of PGC-1α-siRNA against TGF-β1-induced renal interstitial fibrosis Fulltext Access 21 Pages 2018
CS2164 exerts an antitumor effect against human Non-Hodgkin's lymphomas in vitro and in vivo Fulltext Access 21 Pages 2018
Rab7 empowers renal tubular epithelial cells with autophagy-mediated protection against albumin-induced injury Fulltext Access 21 Pages 2018
Synthesis and biological evaluation of some novel diastereoselective benzothiazole β-lactam conjugates Fulltext Access 21 Pages 2018
Discovery of a novel series of α-terpineol derivatives as promising anti-asthmatic agents: Their design, synthesis, and biological evaluation Fulltext Access 21 Pages 2018
The SMYD3 VNTR 3/3 polymorphism confers an increased risk and poor prognosis of hepatocellular carcinoma in a Chinese population Fulltext Access 21 Pages 2018
Mechanism of TRIM25 mediated ubiquitination of metastasis associated protein (MTA) 1 in normal liver cells Fulltext Access 21 Pages 2018
Negative roles of B7-H3 and B7-H4 in the microenvironment of cervical cancer Fulltext Access 21 Pages 2018
Predicting and analyzing early wake-up associated gene expressions by integrating GWAS and eQTL studies Fulltext Access 21 Pages 2018
Label-free quantitative proteomic analysis of drought stress-responsive late embryogenesis abundant proteins in the seedling leaves of two wheat (Triticum aestivum L.) genotypes Fulltext Access 21 Pages 2018
Nucleolin is expressed in patient-derived samples and glioblastoma cells, enabling improved intracellular drug delivery and cytotoxicity Fulltext Access 21 Pages 2018
MicroRNA-30e-5p suppresses non-small cell lung cancer tumorigenesis by regulating USP22-mediated Sirt1/JAK/STAT3 signaling Fulltext Access 21 Pages 2018
Mesenchymal stem cell exosomes promote immunosuppression of regulatory T cells in asthma Fulltext Access 21 Pages 2018
Sodium bicarbonate regulates nitric oxide production in mouse macrophage cell lines stimulated with lipopolysaccharide and interferon γ Fulltext Access 21 Pages 2018
A hypothetical new role for single-stranded DNA binding proteins in the immune system Fulltext Access 21 Pages 2018
Helicobacter pylori induces direct activation of the lymphotoxin beta receptor and non-canonical nuclear factor-kappa B signaling Fulltext Access 21 Pages 2018
Impact of atrial fibrillation in patients with chronic kidney disease undergoing transcatheter aortic valve replacement: Insights of the Healthcare Cost and Utilization Project's National Inpatient Sample Fulltext Access 21 Pages 2018
Novel mutant P277 peptide VP to ameliorate atherogenic side-effects and to preserve anti-diabetic effects in NOD mice Fulltext Access 21 Pages 2018
Discovery of potent liver-selective stearoyl-CoA desaturase-1 (SCD1) inhibitors, thiazole-4-acetic acid derivatives, for the treatment of diabetes, hepatic steatosis, and obesity Fulltext Access 21 Pages 2018
Novel indanone derivatives as MAO B/H3R dual-targeting ligands for treatment of Parkinson's disease Fulltext Access 21 Pages 2018
Design, synthesis and biological evaluation of 3-piperazinecarboxylate sarsasapogenin derivatives as potential multifunctional anti-Alzheimer agents Fulltext Access 21 Pages 2018
The TET2/E-cadherin/β-catenin regulatory loop confers growth and invasion in hepatocellular carcinoma cells Fulltext Access 21 Pages 2018
Mechano-growth factor protects against mechanical overload induced damage and promotes migration of growth plate chondrocytes through RhoA/YAP pathway Fulltext Access 21 Pages 2018
Design, synthesis and ability of non-gold complexed substituted purine derivatives to inhibit LPS-induced inflammatory response Fulltext Access 21 Pages 2018
N-(1,3,4-oxadiazol-2-yl)benzamide analogs, bacteriostatic agents against methicillin- and vancomycin-resistant bacteria Fulltext Access 21 Pages 2018
GRP78 Promotes Hepatocellular Carcinoma proliferation by increasing FAT10 expression through the NF-κB pathway Fulltext Access 21 Pages 2018
Survivin regulated by autophagy mediates hyperglycemia-induced vascular endothelial cell dysfunction Fulltext Access 22 Pages 2018
Long non-coding RNAs expression levels in diffuse large B-cell lymphoma: An in silico analysis Fulltext Access 22 Pages 2018
The emerging risk of exposure to air pollution on cognitive decline and Alzheimer's disease - Evidence from epidemiological and animal studies Fulltext Access 22 Pages 2018
Comprehending a Killer: The Akt/mTOR Signaling Pathways Are Temporally High-Jacked by the Highly Pathogenic 1918 Influenza Virus Fulltext Access 22 Pages 2018
Chitosan oligosaccharides enhance lipid droplets via down-regulation of PCSK9 gene expression in HepG2 cells Fulltext Access 22 Pages 2018
RNA helicase DDX5 participates in oxLDL-induced macrophage scavenger receptor 1 expression by suppressing mRNA degradation Fulltext Access 22 Pages 2018
Genetically-modified bone mesenchymal stem cells with TGF-β3 improve wound healing and reduce scar tissue formation in a rabbit model Fulltext Access 22 Pages 2018
Impact of sex on short term in-hospital outcomes with transcatheter edge-to-edge mitral valve repair Fulltext Access 22 Pages 2018
MiR-138/SIRT1 axis is implicated in impaired learning and memory abilities of cerebral ischemia/reperfusion injured rats Fulltext Access 22 Pages 2018
TOP2A induces malignant character of pancreatic cancer through activating β-catenin signaling pathway Fulltext Access 22 Pages 2018
Macrophages in keloid are potent at promoting the differentiation and function of regulatory T cells Fulltext Access 22 Pages 2018
Hrd1 induces cardiomyocyte apoptosis via regulating the degradation of IGF-1R by sema3a Fulltext Access 22 Pages 2018
Indolyl-isoxazolidines attenuate LPS-stimulated pro-inflammatory cytokines and increase survival in a mouse model of sepsis: Identification of potent lead Fulltext Access 22 Pages 2018
Polypharmacology in HIV inhibition: can a drug with simultaneous action against two relevant targets be an alternative to combination therapy? Fulltext Access 22 Pages 2018
Discovery of meta-sulfamoyl N-hydroxybenzamides as HDAC8 selective inhibitors Fulltext Access 22 Pages 2018
Synthesis and SAR of 4,5-dihydro-1H-pyrazolo[4,3-h]quinazoline derivatives as potent and selective CDK4/6 inhibitors Fulltext Access 22 Pages 2018
Marine derived xyloketal derivatives exhibit anti-stress and anti-ageing effects through HSF pathway in Caenorhabditis elegans Fulltext Access 22 Pages 2018
The association between COX-2 gene rs5275 polymorphism and Nasopharyngeal carcinoma risk Fulltext Access 22 Pages 2018
Part III: Novel checkpoint kinase 2 (Chk2) inhibitors; design, synthesis and biological evaluation of pyrimidine-benzimidazole conjugates Fulltext Access 22 Pages 2018
Design, synthesis and bioevalucation of novel 2,3-dihydro-1H-inden-1-amine derivatives as potent and selective human monoamine oxidase B inhibitors based on rasagiline Fulltext Access 22 Pages 2018
New insights into structure-activity relationship of ipomoeassin F from its bioisosteric 5-oxa/aza analogues Fulltext Access 22 Pages 2018
Molecular design, synthesis and biological evaluation of cage compound-based inhibitors of hepatitis C virus p7 ion channels Fulltext Access 22 Pages 2018
Systematic identification of rabbit LncRNAs reveals functional roles in atherosclerosis Fulltext Access 22 Pages 2018
MBD2-mediated Th17 differentiation in severe asthma is associated with impaired SOCS3 expression Fulltext Access 22 Pages 2018
FTO demethylase activity is essential for normal bone growth and bone mineralization in mice Fulltext Access 22 Pages 2018
Extracellular matrix content and WNT/β-catenin levels of cartilage determine the chondrocyte response to compressive load Fulltext Access 22 Pages 2018
Cold atmospheric plasma conveys selectivity on triple negative breast cancer cells both in vitro and in vivo Fulltext Access 22 Pages 2018
Trx-1 ameliorates learning and memory deficits in MPTP-induced Parkinson's disease model in mice Fulltext Access 22 Pages 2018
Increased TFAM binding to mtDNA damage hot spots is associated with mtDNA loss in aged rat heart Fulltext Access 22 Pages 2018
Paracrine HGF/c-MET enhances the stem cell-like potential and glycolysis of pancreatic cancer cells via activation of YAP/HIF-1α Fulltext Access 23 Pages 2018
Dynamic glucose enhanced MRI of the placenta in a mouse model of intrauterine inflammation Fulltext Access 23 Pages 2018
Molecular imaging of platelet-derived growth factor receptor-alpha (PDGFRα) in papillary thyroid cancer using immuno-PET Fulltext Access 23 Pages 2018
Evaluation of [18F]FNM biodistribution and dosimetry based on whole-body PET imaging of rats Fulltext Access 23 Pages 2018
Sirtuin1 is required for proper trophoblast differentiation and placental development in mice Fulltext Access 23 Pages 2018
MynxGrip® vascular closure device versus manual compression for hemostasis of percutaneous transfemoral venous access closure: Results from a prospective multicenter randomized study Fulltext Access 23 Pages 2018
Quantitative microinjection using fluorescence calibration of streaming microdroplets on a superhydrophobic surface Fulltext Access 23 Pages 2018
Fascin1 promotes gastric cancer progression by facilitatingcell migrationand epithelial-mesenchymal transition Fulltext Access 23 Pages 2018
Mini-peptide RPL41 attenuated retinal neovascularization by inducing degradation of ATF4 in oxygen-induced retinopathy mice Fulltext Access 23 Pages 2018
Stimulus-dependent chromatin dynamics, citrullination, calcium signalling and ROS production during NET formation Fulltext Access 23 Pages 2018
A cardiac glycoside HTF-1 isolated from Helleborus thibetanus Franch displays potent in vitro anti-cancer activity via caspase-9, MAPK and PI3K-Akt-mTOR pathways Fulltext Access 23 Pages 2018
Piperidylthiosemicarbazones Cu(II) complexes with a high anticancer activity by catalyzing hydrogen peroxide to degrade DNA and promote apoptosis Fulltext Access 23 Pages 2018
WDR26/MIP2 interacts with VDAC1 and regulates VDAC1 expression levels in H9c2 cells Fulltext Access 23 Pages 2018
Piperlongumine (piplartine) as a lead compound for anticancer agents - Synthesis and properties of analogues: A mini-review Fulltext Access 23 Pages 2018
Influence of the C-5 substitution in polysubstituted pyrimidines on inhibition of prostaglandin E2 production Fulltext Access 23 Pages 2018
Design and synthesis of novel benzenesulfonamide containing 1,2,3-triazoles as potent human carbonic anhydrase isoforms I, II, IV and IX inhibitors Fulltext Access 23 Pages 2018
Development of novel amino-quinoline-5,8-dione derivatives as NAD(P)H:quinone oxidoreductase 1 (NQO1) inhibitors with potent antiproliferative activities Fulltext Access 23 Pages 2018
Dual inhibitors of the pro-survival proteins Bcl-2 and Mcl-1 derived from natural compound meiogynin A Fulltext Access 23 Pages 2018
Regioselective synthesis of 7-O-esters of the flavonolignan silibinin and SARs lead to compounds with overadditive neuroprotective effects Fulltext Access 23 Pages 2018
Discovery of 2-aminothiazolyl berberine derivatives as effectively antibacterial agents toward clinically drug-resistant Gram-negative Acinetobacter baumanii Fulltext Access 23 Pages 2018
Xanthine oxidase inhibitory activity of natural and hemisynthetic flavonoids from Gardenia oudiepe (Rubiaceae) in vitro and molecular docking studies Fulltext Access 23 Pages 2018
Design, synthesis, and evaluation of NDGA analogues as potential anti-ischemic stroke agents Fulltext Access 23 Pages 2018
Amlexanox provides a potential therapy for nonsense mutations in the lysosomal storage disorder Aspartylglucosaminuria Fulltext Access 23 Pages 2018
99mTc labeled D(LPR): A novel retro-inverso peptide for VEGF receptor-1 targeted tumor imaging Fulltext Access 23 Pages 2018
Evaluation of the p53 and Thioredoxin reductase in sperm from asthenozoospermic males in comparison to normozoospermic males Fulltext Access 23 Pages 2018
The effect of the electrophilic fatty acid nitro-oleic acid on TRP channel function in sensory neurons Fulltext Access 23 Pages 2018
Increased TERRA levels and RNase H sensitivity are conserved hallmarks of post-senescent survivors in budding yeast Fulltext Access 23 Pages 2018
Inhibition of miR-135b by SP-1 promotes hypoxia-induced vascular endothelial cell injury via HIF-1α Fulltext Access 23 Pages 2018
Overexpression of miR-133 decrease primary endothelial cells proliferation and migration via FGFR1 targeting Fulltext Access 23 Pages 2018
Long non-coding RNA UCA1 upregulation promotes the migration of hypoxia-resistant gastric cancer cells through the miR-7-5p/EGFR axis Fulltext Access 23 Pages 2018
TRIM24 promotes hepatocellular carcinoma progression via AMPK signaling Fulltext Access 23 Pages 2018
Artemin regulates CXCR4 expression to induce migration and invasion in pancreatic cancer cells through activation of NF-κB signaling Fulltext Access 23 Pages 2018
6-Shogaol induces caspase-independent paraptosis in cancer cells via proteasomal inhibition Fulltext Access 23 Pages 2018
mmu-miR-1963 negatively regulates the ameloblast differentiation of LS8 cell line by directly targeting Smoc2 3'UTR Fulltext Access 23 Pages 2018
Cytotoxic T cell responses to Streptococcus are associated with improved prognosis of oral squamous cell carcinoma Fulltext Access 23 Pages 2018
Preclinical study of an 18F-labeled glutamine derivative for cancer imaging Fulltext Access 23 Pages 2018