Synthesis and biological evaluation of benzimidazole derivatives as potent AMP-activated protein kinase activators Fulltext Access 29 Pages 2006
A Multiphase Microscopic Diffusion Model for Stratum Corneum permeability. I. Formulation, Solution, and Illustrative Results for Representative Compounds Fulltext Access 29 Pages 2006
Solvent and in situ catalyst preparation impacts upon Noyori reductions of aryl-chloromethyl ketones: application to syntheses of chiral 2-amino-1-aryl-ethanols Fulltext Access 29 Pages 2006
Recent developments in the clinical activity of topoisomerase-1 inhibitors Fulltext Access 29 Pages 2006
Qualitative simulation of the carbon starvation response in Escherichia coli Fulltext Access 29 Pages 2006
Design, synthesis, structure–activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists Fulltext Access 30 Pages 2006
A journey across the sequential development of macrolides and ketolides related to erythromycin Fulltext Access 30 Pages 2006
Chiral non-racemic sulfinimines: versatile reagents for asymmetric synthesis Fulltext Access 37 Pages 2006
Neuropharmacology of cognition and memory: A unifying theory of neuromodulator imbalance in psychiatry and amnesia Fulltext Access 38 Pages 2006
The chemistry of recently isolated naturally occurring quinazolinone alkaloids Fulltext Access 40 Pages 2006
Integration of hepatic drug transporters and phase II metabolizing enzymes: Mechanisms of hepatic excretion of sulfate, glucuronide, and glutathione metabolites Fulltext Access 40 Pages 2006
Les systèmes de délivrance des médicaments : un réel progress pour la thérapeutique* Fulltext Access 41 Pages 2006
Heterocyclic compounds with a silicon atom and another non-adjacent different heteroatom Fulltext Access 43 Pages 2006
Tetrahedron report number 762Synthesis and biological activity of pyrrole, pyrroline and pyrrolidine derivatives with two aryl groups on adjacent positions Fulltext Access 44 Pages 2006
Synthesis and role of glycosylthio heterocycles in carbohydrate chemistry Fulltext Access 56 Pages 2006
Lipase-promoted dynamic kinetic resolution of racemic β-hydroxyalkyl sulfones Fulltext Access 4 Pages 2005
Organocatalysis of asymmetric epoxidation mediated by iminium salts: comments on the mechanism Fulltext Access 4 Pages 2005
Diastereoselective rhodium-catalyzed nitrene transfer starting from chiral sulfonimidamide-derived iminoiodanes Fulltext Access 4 Pages 2005
Diastereoselective alkylation of chiral 2-imidazolidinone glycolates: asymmetric synthesis of α-hydroxy carboxylic acids Fulltext Access 4 Pages 2005
An in situ silver cationization method for hydrocarbon mass spectrometry Fulltext Access 4 Pages 2005
Phosphoramidite ligands for the enantioselective iridium-catalyzed asymmetric hydroboration of meso-bicyclic hydrazines Fulltext Access 4 Pages 2005
Synthesis of optically active (+)-2-benzyl-, (+)-2-octyl-, and (+)-2-tetradec-5′-enylcyclobutanones via metallated chiral imines or hydrazones Fulltext Access 4 Pages 2005
A versatile synthesis of phosphine–aminophosphine ligands for asymmetric catalysis Fulltext Access 4 Pages 2005
Ionic-Liquid Matrices for Improved Analysis of Phospholipids by MALDI-TOF Mass Spectrometry Fulltext Access 4 Pages 2005
Unusual base dependent enantioselectivity in a transfer hydrogenation using axially chiral Ir(III)-catalysts Fulltext Access 4 Pages 2005
Chiral separation of amino acids by chiral octamide derivatives of calixarenes derived from resorcinol by impregnation on a polymeric support Fulltext Access 4 Pages 2005
A highly enantioselective, moderately anti-selective aldol reaction using a novel hydrazone moiety as stereo director Fulltext Access 4 Pages 2005
Stereocontrolled synthesis of conformationally restricted enantiopure triols and dihydroxy acids based on the norbornane framework Fulltext Access 4 Pages 2005
Microwave-assisted ethylene–alkyne cross-metathesis: synthesis of chiral 2-(N-1-acetyl-1-arylmethyl)-1,3-butadienes Fulltext Access 4 Pages 2005
Stereochemistry of the Diels–Alder reaction at high pressure: diastereo- and enantioselective [4+2]cycloaddition of buta-1,3-diene to glyoxylic acid derivatives catalysed by (salen) chromium(III) complexes Fulltext Access 4 Pages 2005
The first total synthesis of (R)-7-butyl-6,8-dihydroxy-3-pentylisochroman-1-one Fulltext Access 4 Pages 2005
Synthesis and characterization of axially chiral enantiopure novel dendrimers Fulltext Access 4 Pages 2005
Enzymatic resolution of (±)-2-endo-hydroxymethyl and acetoxymethyl substituted hexachloronorbornene derivatives Fulltext Access 4 Pages 2005
Chiral tertiary alcohols from a trans-1-arenesulfonyl-amino-2-isoborneolsulfonylaminocyclohexane-catalyzed addition of organozincs to ketones Fulltext Access 4 Pages 2005
Improved catalytic asymmetric carbon–carbon bond formation using combinations of chiral and achiral monodentate ligands Fulltext Access 4 Pages 2005
Furanoside thioether-phosphinite ligands for Rh-catalyzed asymmetric hydrosilylation of ketones Fulltext Access 4 Pages 2005
Enzymatic desymmetrization of 2-amino-2-methyl-1,3-propanediol: asymmetric synthesis of (S)-N-Boc-N,O-isopropylidene-α-methylserinal and (4R)-methyl-4-[2-(thiophen-2-yl)ethyl]oxazolidin-2-one Fulltext Access 4 Pages 2005
Asymmetric conjugate addition of metal alkyl reagents catalyzed by copper complexes with BINPO: a hemilabile P,O-heterobidentate axially chiral ligand Fulltext Access 4 Pages 2005
‘Green’ synthesis of important pharmaceutical building blocks: enzymatic access to enantiomerically pure α-chloroalcohols Fulltext Access 4 Pages 2005
Catalytic enantioselective Michael addition in the synthesis of α-aminophosphonates Fulltext Access 4 Pages 2005