Asymmetric reduction of acetophenone using lithium aluminium hydride modified with some novel amino alcohol Schiff bases Fulltext Access 4 Pages 2005
Construction of quaternary carbon stereocentres: catalytic enantioselective allylation assisted by a bimetallic catalytic system Fulltext Access 4 Pages 2005
Asymmetric reduction of a variety of ketones with a recombinant carbonyl reductase: identification of the gene encoding a versatile biocatalyst Fulltext Access 4 Pages 2005
Lipase-catalyzed alcoholysis of diol dibenzoates: selective enzymatic access to the 2-benzoyl ester of 1,2-propanediol and preparation of the enantiomerically pure (R)-1-O-benzoyl-2-methylpropane-1,3-diol Fulltext Access 4 Pages 2005
Efficient chromatographic resolution of a configurationally fragile atropisomeric diphenol via its N-(α)-Boc-tryptophan diesters Fulltext Access 4 Pages 2005
A chiron approach to (1R,2R,5S,7S)-2-hydroxy-exo-brevicomin: a component of the volatiles produced by the male mountain pine beetle, Dendroctonus ponderosae Fulltext Access 4 Pages 2005
Chemoenzymatic synthesis of both enantiomers of 2-chloro-1-(2-furyl)ethanol Fulltext Access 4 Pages 2005
Design and solid-phase synthesis of chiral acyclic and cyclic diamine ligands Fulltext Access 4 Pages 2005
Immobilization does not influence the enantioselectivity of CAL-B catalyzed kinetic resolution of secondary alcohols Fulltext Access 4 Pages 2005
Enantioselective reduction of ketones with NaBH4/diglyme possibly catalysed by trialkyl borate: optically active sec-alcohols from prochiral ketones with catalytic (â)-menthol: autocatalysis option Fulltext Access 4 Pages 2005
Design, synthesis and evaluation of racemic 1-(4-hydroxyphenyl)-2-[3-(substituted phenoxy)-2-hydroxy-1-propyl]amino-1-propanol hydrochlorides as novel uterine relaxants Fulltext Access 4 Pages 2005
Investigation of glycine α-ketoamide HCV NS3 protease inhibitors: Effect of carboxylic acid isosteres Fulltext Access 4 Pages 2005
Synthesis of some pyrazole derivatives and preliminary investigation of their affinity binding to P-glycoprotein Fulltext Access 4 Pages 2005
The first asymmetric addition of organogallium to aldehydes catalyzed by chiral titanium catalysts Fulltext Access 4 Pages 2005
Molluscicidal activity of synthetic lapachol amino and hydrogenated derivatives Fulltext Access 4 Pages 2005
An efficient asymmetric synthesis of (S)-atenolol: using hydrolytic kinetic resolution Fulltext Access 4 Pages 2005
Enantioselective hydrogenation of ethyl pyruvate catalyzed by alumina support rhodium modified with quinine Fulltext Access 4 Pages 2005
2-Aryl-5,5-bisoxazolin-2-yl[1,3]dioxanes as solution phase and immobilised ligands for highly enantioselective cyclopropanations Fulltext Access 4 Pages 2005
Primary amine catalyzed direct asymmetric aldol reaction assisted by water Fulltext Access 4 Pages 2005
Boron trifluoride etherate-assisted ring opening of ethylene oxide by a chiral organolithium: enantioselective synthesis of (R)-N-Boc-2-(2-hydroxyethyl)pyrrolidine Fulltext Access 4 Pages 2005
The influence of solvent choice, acid activation and surfactant addition on the hydrolytic kinetic resolution (HKR) of terminal epoxides Fulltext Access 4 Pages 2005
9H-Xanthene-9-carboxylic acid [1,2,4]oxadiazol-3-yl- and (2H-tetrazol-5-yl)-amides as potent, orally available mGlu1 receptor enhancers Fulltext Access 4 Pages 2005
Dihydrobenzopyran skeleton from β-lactams: a stereoselective ring opening-ring closure reaction sequence Fulltext Access 4 Pages 2005
Efficient preparation of (1â²R)-(â)-1-(2â²-hydroxy-1â²-phenylethyl)piperidin-2-one: synthesis of (2â²S,3R)-(+)-stenusine Fulltext Access 4 Pages 2005
The synthesis of new planar chiral heterobidentate chelate ligands for asymmetric catalysis Fulltext Access 4 Pages 2005
New bidentate alkoxy-NHC ligands for enantioselective copper-catalysed conjugate addition Fulltext Access 4 Pages 2005
Synthesis of N-linked glycopeptides on solid support and their evaluation as protease substrates Fulltext Access 4 Pages 2005
Preliminary studies on the incorporation of sugars into naphthoquinones: synthesis of (1R,2S,3S,4R,4aS,11bS)-2-(benzyloxy)-1,2,3,4,4a,5-hexahydro-1,3,4-trihydroxy-11bH-benzo[b]carbazole-6,11-dione Fulltext Access 4 Pages 2005
A novel benzoyl-type fluorous protecting group for use in fluorous synthesis Fulltext Access 4 Pages 2005
Transforming bivalent ligands into retractable enzyme inhibitors through polypeptide–protein interactions Fulltext Access 4 Pages 2005
Discovery of 4-heteroarylbicyclo[2.2.2]octyltriazoles as potent and selective inhibitors of 11β-HSD1: Novel therapeutic agents for the treatment of metabolic syndrome Fulltext Access 4 Pages 2005
Photocurable hard and porous biomaterials from ROMP precursors cross-linked with diyl radicals Fulltext Access 4 Pages 2005
N-[(3S)-1-Benzylpyrrolidin-3-yl]-(2-thienyl)benzamides: Human dopamine D4 ligands with high affinity for the 5-HT2A receptor Fulltext Access 4 Pages 2005
Structure–activity relationship studies on a series of cyclohexylpiperazines bearing a phanylacetamide as ligands of the human melanocortin-4 receptor Fulltext Access 4 Pages 2005
Self-complementary peptides for the formation of collagen-like triple helical supramolecules Fulltext Access 4 Pages 2005
Synthesis and antitubercular activity of 2-hydroxy-aminoalkyl derivatives of diaryloxy methano phenanthrenes Fulltext Access 4 Pages 2005
A small library of trisubstituted pyrimidines as antimalarial and antitubercular agents Fulltext Access 4 Pages 2005
In silico fragment-based discovery of indolin-2-one analogues as potent DNA gyrase inhibitors Fulltext Access 4 Pages 2005
Phosphinate, sulfonate, and sulfonamidate dipeptides as potential inhibitors of Escherichia coli aminopeptidase N Fulltext Access 4 Pages 2005
Design, synthesis, and evaluation of octahydropyranopyrrole-based inhibitors of mammalian ribonucleotide reductase Fulltext Access 4 Pages 2005
Highly sensitive peptide-based probes for protein tyrosine phosphatase activity utilizing a fluorogenic mimic of phosphotyrosine Fulltext Access 4 Pages 2005
Synthesis and ex vivo evaluation of carbon-11 labelled N-(4-methoxybenzyl)-N′-(5-nitro-1,3-thiazol-2-yl)urea ([11C]AR-A014418): A radiolabelled glycogen synthase kinase-3β specific inhibitor for PET studies Fulltext Access 4 Pages 2005
Synthesis and in vivo evaluation of a new PET radioligand for studying sigma-2 receptors Fulltext Access 4 Pages 2005
Calorimetric and computational study of enthalpy of formation of 3,6-dibutanoic-1,2,4,5-tetroxane Fulltext Access 4 Pages 2005
Indole alkaloids from Tabernaemontana australis (Müell. Arg) Miers that inhibit acetylcholinesterase enzyme Fulltext Access 4 Pages 2005
Human serum transferrin cobalt complex: Stability and cellular uptake of cobalt Fulltext Access 4 Pages 2005
Asymmetric hydrogenation of enamides with a new chiral phosphine–phosphinite ligand Fulltext Access 4 Pages 2005
Candida viswanathii as a novel biocatalyst for stereoselective reduction of heteroaryl methyl ketones: a highly efficient enantioselective synthesis of (S)-α-(3-pyridyl)ethanol Fulltext Access 4 Pages 2005
Novel chiral copper complexes of N,P-ferrocenyl ligands with central and planar chirality as efficient catalyst for asymmetric addition of diethylzinc to imines Fulltext Access 4 Pages 2005
Microbial Baeyer–Villiger oxidation applied to the synthesis of the N-protected (1R,5R)-Geisman–Waiss lactone Fulltext Access 4 Pages 2005
Synthesis and biological activity of macrocyclic inhibitors of hepatitis C virus (HCV) NS3 protease Fulltext Access 4 Pages 2005
Optimization of piperazinebenzylamines with a N-(1-methoxy-2-propyl) side chain as potent and selective antagonists of the human melanocortin-4 receptor Fulltext Access 4 Pages 2005
Potent and selective MC-4 receptor agonists based on a novel disulfide scaffold Fulltext Access 4 Pages 2005
The synthesis and antioxidant activity of the Schiff bases of chitosan and carboxymethyl chitosan Fulltext Access 4 Pages 2005
The hydrogen peroxide induced enhancement of DNA cleavage in the ambient light photolysis of CpFe(CO)2Ph: A potential strategy for targeting cancer cells Fulltext Access 4 Pages 2005
Hydroxylated N-alkyl-4-piperidinyl-2,3-diarylpyrrole derivatives as potent broad-spectrum anticoccidial agents Fulltext Access 4 Pages 2005
8-Substituted 3,4-dihydroquinolinones as a novel scaffold for atypical antipsychotic activity Fulltext Access 4 Pages 2005
Glycolipids and other constituents from Desmodium gangeticum with antileishmanial and immunomodulatory activities Fulltext Access 4 Pages 2005
Synthesis and antibacterial activity of N-[2-(5-bromothiophen-2-yl)-2-oxoethyl] and N-[(2-5-bromothiophen-2-yl)-2-oximinoethyl] derivatives of piperazinyl quinolones Fulltext Access 4 Pages 2005
The enigma of coproporphyrinogen oxidase: How does this unusual enzyme carry out oxidative decarboxylations to afford vinyl groups? Fulltext Access 4 Pages 2005
Synthesis and in vitro and in vivo antimycobacterial activity of isonicotinoyl hydrazones Fulltext Access 4 Pages 2005
Synthesis and evaluation of a series of tropane analogues as novel vesicular monoamine transporter-2 ligands Fulltext Access 4 Pages 2005
Privileged structure-based ligands for melanocortin receptors—tetrahydroquinolines, indoles, and aminotetralines Fulltext Access 4 Pages 2005
A synthesis of 3-deoxydihydrolycoricidine: Refinement of a structurally minimum pancratistatin pharmacophore Fulltext Access 4 Pages 2005
Orally bioavailable highly potent HIV protease inhibitors against PI-resistant virus Fulltext Access 4 Pages 2005
Inhibitors of the serotonin transporter protein (SERT): The design and synthesis of biotinylated derivatives of 3-(1,2,3,6-tetrahydro-pyridin-4-yl)-1H-indoles. High-affinity serotonergic ligands for conjugation with quantum dots Fulltext Access 4 Pages 2005
Photoregulation of DNA polymerase I (Klenow) with caged fluorescent oligodeoxynucleotides Fulltext Access 4 Pages 2005
Synthesis and biological evaluation of novel bisheterocycle-containing compounds as potential anti-influenza virus agents Fulltext Access 4 Pages 2005