Synthesis of terminally protected (S)-β3-H-DOPA by Arndt-Eistert homologation: an approach to crowned β-peptides Fulltext Access 8 Pages 2005
Fluorescent sensors for amino acid anions based on calix[4]arenes bearing two dansyl groups Fulltext Access 8 Pages 2005
Synthesis of (R)-ar-turmerone and its conversion to (R)-ar-himachalene, a pheromone component of the flea beetle: (R)-ar-himachalene is dextrorotatory in hexane, while levorotatory in chloroform Fulltext Access 8 Pages 2005
Crystallographic analysis of the interactions of Drosophila melanogaster Golgi α-mannosidase II with the naturally occurring glycomimetic salacinol and its analogues Fulltext Access 8 Pages 2005
Chiral imidazole derivatives synthesis from enantiopure N-protected α-amino acids Fulltext Access 8 Pages 2005
The enantiomeric recognition of dihydropyrimidonic compounds by chiral selectors derived from 4- or 2-chloro-3,5-dinitrobenzoic acid Fulltext Access 8 Pages 2005
A study of substituent effects on the enantioselective trimethylsilylcyanation of benzaldehyde catalyzed by chiral Schiff base-titanium(IV) complexes Fulltext Access 8 Pages 2005
Nitrite-mediated hydrolysis of epoxides catalyzed by halohydrin dehalogenase from Agrobacterium radiobacter AD1: a new tool for the kinetic resolution of epoxides Fulltext Access 8 Pages 2005
Alternative approaches towards glycosylated eight-membered ring compounds employing Claisen rearrangement of mono and disaccharide allyl vinyl ether precursors Fulltext Access 8 Pages 2005
Removal of the acyl donor residue allows the use of simple alkyl esters as acyl donors for the dynamic kinetic resolution of secondary alcohols Fulltext Access 8 Pages 2005
Spontaneous resolution of a novel chiral coordination polymer through supramolecular interactions and solvent symmetry breaking Fulltext Access 8 Pages 2005
Synthesis of novel types of divalent saccharide structures by a ketene acetal Claisen rearrangement Fulltext Access 8 Pages 2005
Resolution of inherently chiral anti-O,Oâ²-dialkylated calix[4]arenes and determination of their absolute stereochemistries by CD and X-ray methods Fulltext Access 8 Pages 2005
Comparative molecular similarity indices analysis (CoMSIA) studies of 1,2-naphthoquinone derivatives as PTP1B inhibitors Fulltext Access 8 Pages 2005
Structure–activity relationship for aryl and heteroaryl boronic acid inhibitors of hormone-sensitive lipase Fulltext Access 8 Pages 2005
Synthesis and antiamoebic activities of 1-N-substituted cyclised pyrazoline analogues of thiosemicarbazones Fulltext Access 8 Pages 2005
Heterocyclic inhibitors of dihydrodipicolinate synthase are not competitive Fulltext Access 8 Pages 2005
Fluorosubstitution and 7-alkylation as prospective modifications of biologically active 6-aryl derivatives of tricyclic acyclovir and ganciclovir analogues Fulltext Access 8 Pages 2005
Design, synthesis, antibacterial and QSAR studies of benzimidazole and imidazole chloroaryloxyalkyl derivatives Fulltext Access 8 Pages 2005
Novel A-ring analogs of the hormone 1α,25-dihydroxyvitamin D3: synthesis and preliminary biological evaluation Fulltext Access 8 Pages 2005
1,2,4-Triazino-[5,6b]indole derivatives: effects of the trifluoromethyl group on in vitro antimalarial activity Fulltext Access 8 Pages 2005
Design, synthesis and biological evaluation of novel riccardiphenol analogs Fulltext Access 8 Pages 2005
The novel GABA adamantane derivative (AdGABA): design, synthesis, and activity relationship with gabapentin Fulltext Access 8 Pages 2005
Quantitative structure and aldose reductase inhibitory activity relationship of 1,2,3,4-tetrahydropyrrolo[1,2-a]pyrazine-4-spiro-3â²-pyrrolidine-1,2â²,3,5â²-tetrone derivatives Fulltext Access 8 Pages 2005
Inhibition of classical pathway of complement activation with negative charged derivatives of bisphenol A and bisphenol disulphates Fulltext Access 8 Pages 2005
Effects of 8-methyl-2â²-deoxyadenosine incorporation into quadruplex forming oligodeoxyribonucleotides Fulltext Access 8 Pages 2005
Spectrometric studies of cytotoxic protoberberine alkaloids binding to double-stranded DNA Fulltext Access 8 Pages 2005
Discovery of melanin-concentrating hormone receptor R1 antagonists using high-throughput synthesis Fulltext Access 8 Pages 2005
Synthesis and evaluation of N-(5-fluoro-2-phenoxyphenyl)-N-(2-[18F]fluoromethoxy-d2-5-methoxybenzyl)acetamide: a deuterium-substituted radioligand for peripheral benzodiazepine receptor Fulltext Access 8 Pages 2005
Synthesis and potent antimicrobial activity of some novel 2-phenyl or methyl-4H-1-benzopyran-4-ones carrying amidinobenzimidazoles Fulltext Access 8 Pages 2005
Synthesis and cellular studies of an octa-anionic 5,10,15,20-tetra[3,5-(nido-carboranylmethyl)phenyl]porphyrin (H2OCP) for application in BNCT Fulltext Access 8 Pages 2005
Thio-heterocylic naphthalimides with aminoalkyl side chains: novel alternative tools for photodegradation of genomic DNA without impairment on bioactivities of proteins Fulltext Access 8 Pages 2005
Synthesis and biodistribution of [11C]R116301, a promising PET ligand for central NK1 receptors Fulltext Access 8 Pages 2005
Synthesis and anticancer activity of benzyloxybenzaldehyde derivatives against HL-60 cells Fulltext Access 8 Pages 2005
3D QSAR Markov model for drug-induced eosinophilia-theoretical prediction and preliminary experimental assay of the antimicrobial drug G1 Fulltext Access 8 Pages 2005
Synthesis and hybridization properties of the conjugates of oligonucleotides and stabilization agents. Part 3 Fulltext Access 8 Pages 2005
Synthesis of phthalates of betulinic acid and betulin with cytotoxic activity Fulltext Access 8 Pages 2005
Synthesis of 2-amino-6-(4-[11C]methoxyphenylthio)-9-[2-(phosphonomethoxy)ethyl]purine bis(2,2,2-trifluoroethyl) ester as a novel potential PET gene reporter probe for HBV and HSV-tk in cancers Fulltext Access 8 Pages 2005
Structure-activity relationship study on 13-deoxytedanolide, a highly antitumor macrolide from the marine sponge Mycale adhaerens Fulltext Access 8 Pages 2005
Asymmetric synthesis and biological evaluation of the enantiomeric isomers of the immunosuppressive FTY720-phosphate Fulltext Access 8 Pages 2005
Design and synthesis of (Z)-1,2-diphenyl-1-(4-methanesulfonamidophenyl)alk-1-enes and (Z)-1-(4-azidophenyl)-1,2-diphenylalk-1-enes: novel inhibitors of cyclooxygenase-2 (COX-2) with anti-inflammatory and analgesic activity Fulltext Access 8 Pages 2005
Binding of β-d-glucopyranosyl bismethoxyphosphoramidate to glycogen phosphorylase b: kinetic and crystallographic studies Fulltext Access 8 Pages 2005
Synthesis and structure-activity relationships of 6-{4-[(3-fluorobenzyl)oxy]phenoxy}nicotinamide derivatives as a novel class of NCX inhibitors: a QSAR study Fulltext Access 8 Pages 2005
A radial distribution function approach to predict A2B agonist effect of adenosine analogues Fulltext Access 8 Pages 2005
The effective molarity of the substrate phosphoryl group in the transition state for yeast OMP decarboxylase Fulltext Access 8 Pages 2005
A theoretical study of the different radical-scavenging activities of catechin, quercetin, and a rationally designed planar catechin Fulltext Access 8 Pages 2005
Stereospecificity of hydride transfer in NAD+-catalyzed 2-deoxy-scyllo-inosose synthase, the key enzyme in the biosynthesis of 2-deoxystreptamine-containing aminocyclitol antibiotics Fulltext Access 8 Pages 2005
Interpenetrating chiral 2D grid nets: hetero- versus homochiral 3D polycatenation in the crystal self-assembly of (RS)- and (R)-1,1′-binaphthalene-2,2′,6,6′-tetracarboxylic acids Fulltext Access 8 Pages 2005
Intrastrand base-stacking buttresses widening of major groove in interstrand cross-linked B-DNA Fulltext Access 8 Pages 2005
Understanding human 15-hydroxyprostaglandin dehydrogenase binding with NAD+ and PGE2 by homology modeling, docking and molecular dynamics simulation Fulltext Access 8 Pages 2005
New ether diglycosides from Matayba guianensis with antiplasmodial activity Fulltext Access 8 Pages 2005
Chemical regulation of abscisic acid catabolism in plants by cytochrome P450 inhibitors Fulltext Access 8 Pages 2005
A new polyamine derivative, a structural analog of spermine, with in vivo activity as an inhibitor of ethanol appetite Fulltext Access 8 Pages 2005
The first total synthesis of naturally occurring (+)-gymnasterkoreayne F and its enantiomer Fulltext Access 8 Pages 2005
Synthesis of optically active α-methylamino acids and amides through biocatalytic kinetic resolution of amides Fulltext Access 8 Pages 2005
Highly stereoselective synthesis of antitumor agents: both enantiomers of goniothales diol, altholactone, and isoaltholactone Fulltext Access 8 Pages 2005
Cymantrene-based iminodiamidophosphites: the first phosphite-type ligands with planar chirality Fulltext Access 8 Pages 2005
Napthalimidobenzamide DB-51630: a novel DNA binding agent inducing p300 gene expression and exerting a potent anti-cancer activity Fulltext Access 8 Pages 2005
Synthesis and determination of alkali metal binding selectivities of chiral macrocyclic bisamides derived from d-mannitol and l-threitol possessing 2,6-pyridinedicarboxamide subunits Fulltext Access 8 Pages 2005
Crystallization-induced asymmetric transformations (CIAT): stereoconvergent acid-catalyzed lactonization of substituted 2-amino-4-aryl-4-hydroxybutanoic acids Fulltext Access 8 Pages 2005
Fluorescence screening of tartaric acid-derived azamacrocycles synthesized via sequential hydroformylation/reductive amination as potential ligands for asymmetric catalysis Fulltext Access 8 Pages 2005
Synthesis of 2,4,5-trisubstituted thiazoline via a novel stereoselective intramolecular conjugate addition Fulltext Access 8 Pages 2005
Synthesis of calix[4]arene derivatives bearing chiral pendant groups as ligands for enantioselective catalysis Fulltext Access 8 Pages 2005
Optically active palladium-catalyzed asymmetric amination of aryl halide Fulltext Access 8 Pages 2005
Enantioselective synthesis of (2R,3R)- and (2S,3S)-2-[(3-chlorophenyl)-(2-methoxyphenoxy)methyl]morpholine Fulltext Access 8 Pages 2005
Synthesis of two new chiral fluorous bis(oxazolines) and their applications as ligands in catalytic asymmetric reactions Fulltext Access 8 Pages 2005
Novel chiral bis(oxazolines): synthesis and application as ligands in the copper-catalyzed enantioselective conjugate addition of diethylzinc to enones Fulltext Access 8 Pages 2005
QSAR study on thiazole and thiadiazole analogues as antagonists for the adenosine A1 and A3 receptors Fulltext Access 8 Pages 2005
1,4-Dihydropyridine derivatives as calcium channel modulators: the role of 3-methoxy-flavone moiety Fulltext Access 8 Pages 2005
Linear indices of the 'macromolecular graph's nucleotides adjacency matrix' as a promising approach for bioinformatics studies. Part 1: Prediction of paromomycin's affinity constant with HIV-1 Ψ-RNA packaging region Fulltext Access 8 Pages 2005
Biocatalysed synthesis of β-O-glucosides from 9-fluorenon-2-carbohydroxyesters. Part 3: IFN-inducing and anti-HSV-2 properties Fulltext Access 8 Pages 2005
Biotin-labeled abscisic acid as a probe for investigating abscisic acid binding sites on plasma membranes of barley aleurone protoplasts Fulltext Access 8 Pages 2005
An estradiol-conjugate for radiolabelling with 177Lu: an attempt to prepare a radiotherapeutic agent Fulltext Access 8 Pages 2005
Discovery of a novel small molecule, 1-ethoxy-3-(3,4-methylenedioxyphenyl)-2-propanol, that induces apoptosis in A549 human lung cancer cells Fulltext Access 8 Pages 2005
Towards new boron carriers for boron neutron capture therapy: metallacarboranes and their nucleoside conjugates Fulltext Access 8 Pages 2005
Docking simulation with a purine nucleoside specific homology model of deoxycytidine kinase, a target enzyme for anticancer and antiviral therapy Fulltext Access 8 Pages 2005
Tetrazolyl isoxazole amino acids as ionotropic glutamate receptor antagonists: Synthesis, modelling and molecular pharmacology Fulltext Access 8 Pages 2005
4-Aminoquinoline quinolizidinyl- and quinolizidinylalkyl-derivatives with antimalarial activity Fulltext Access 8 Pages 2005
Macroporous chiral ruthenium porphyrin polymers: a new solid-phase material used as a device for catalytic asymmetric carbene transfer Fulltext Access 8 Pages 2005
Synthesis and evaluation of the permeability transition inhibitory characteristics of paramagnetic and diamagnetic amiodarone derivatives Fulltext Access 8 Pages 2005
Anti-inflammatory activity and QSAR studies of compounds isolated from Hyacinthaceae species and Tachiadenus longiflorus Griseb. (Gentianaceae) Fulltext Access 8 Pages 2005
Syntheses of quinolone hydrochloride enantiomers from synthons (R)- and (S)-2-methylpiperazine Fulltext Access 8 Pages 2005
Evaluation of macrocyclic Grb2 SH2 domain-binding peptide mimetics prepared by ring-closing metathesis of C-terminal allylglycines with an N-terminal β-vinyl-substituted phosphotyrosyl mimetic Fulltext Access 8 Pages 2005
Stabilization of guanine quadruplex DNA by the binding of porphyrins with cationic side arms Fulltext Access 8 Pages 2005
Inhibitory effects of flavonol glycosides from Cinnamomum osmophloeum on inflammatory mediators in LPS/IFN-γ-activated murine macrophages Fulltext Access 8 Pages 2005
Copper-metalated peptide palindrome derived from prion octarepeat: synthesis, aggregation, and oxidative transformations Fulltext Access 8 Pages 2005
Synthesis and evaluation of bifunctional chelating agents derived from bis(2-aminophenylthio)alkane for radioimaging with 99mTc Fulltext Access 8 Pages 2005
Syntheses and binding affinities of 6-nitroquipazine analogues for serotonin transporter. Part 4: 3-Alkyl-4-halo-6-nitroquipazines Fulltext Access 8 Pages 2005
Synthesis and characterization of azole isoflavone inhibitors of aromatase Fulltext Access 8 Pages 2005