α-Aminoalkylphosphonates as a tool in experimental optimisation of P1 side chain shape of potential inhibitors in S1 pocket of leucine- and neutral aminopeptidases Fulltext Access 8 Pages 2005
Microwave-assisted enzyme-catalyzed reactions in various solvent systems Fulltext Access 8 Pages 2005
Synthesis and cytotoxic activity of 2-acyl-1H-indole-4,7-diones on human cancer cell lines Fulltext Access 8 Pages 2005
The interaction between resistance modifiers such as pyrido[3,2-g]quinoline, aza-oxafluorene and pregnane derivatives with DNA, plasmid DNA and tRNA Fulltext Access 8 Pages 2005
Synthesis of novel amino and acetyl amino-4-methylcoumarins and evaluation of their antioxidant activity Fulltext Access 8 Pages 2005
Molecular basis of the low activity of antitumor anthracenediones, mitoxantrone and ametantrone, in oxygen radical generation catalyzed by NADH dehydrogenase. Enzymatic and molecular modelling studies Fulltext Access 8 Pages 2005
Novel Cu(II) quinoxaline N1,N4-dioxide complexes as selective hypoxic cytotoxins Fulltext Access 8 Pages 2005
Benzoyl and/or benzyl substituted 1,2,3-triazoles as potassium channel activators. VIII Fulltext Access 8 Pages 2005
Preparation of celecoxib-dimethyl-β-cyclodextrin inclusion complex: characterization and in vitro permeation study Fulltext Access 8 Pages 2005
The influence and utility of varying field strength for the separation of tryptic peptides by ion mobility-mass spectrometry Fulltext Access 8 Pages 2005
1-N-Substituted Thiocarbamoyl-3-Phenyl-2-Pyrazolines: Synthesis and In Vitro Antiamoebic Activities Fulltext Access 8 Pages 2005
Synthesis and potent antibacterial activity against MRSA of some novel 1,2-disubstituted-1H-benzimidazole-N-alkylated-5-carboxamidines Fulltext Access 8 Pages 2005
Synthesis and properties of isocannabinoid and cholesterol derivatized rhamnosurfactants: application to liposomal targeting of keratinocytes and skin Fulltext Access 8 Pages 2005
Synthesis, antibacterial, antifungal activity and interaction of CT-DNA with a new benzimidazole derived Cu(II) complex Fulltext Access 8 Pages 2005
Synthesis and antiproliferative activity of 2,6-Dibenzylamino-3,5-dicyanopyridines on human cancer cell lines Fulltext Access 8 Pages 2005
Synthesis and antimicrobial activity of some novel derivatives of benzofuran: part 1. Synthesis and antimicrobial activity of (benzofuran-2-yl)(3-phenyl-3-methylcyclobutyl) ketoxime derivatives Fulltext Access 8 Pages 2005
Synthesis, antimicrobial activity and molecular modeling of cobalt and nickel complexes containing the bulky ligand: bis[N-(2,6-diisopropylphenyl)imino] acenaphthene Fulltext Access 8 Pages 2005
Synthesis of 2,6-diphenylpyrazine derivatives and their DNA binding and cytotoxic properties Fulltext Access 8 Pages 2005
A fluorescent chemosensor for Al3+ based on julolidine and tryptophan moieties Fulltext Access 8 Pages 2005
Nγ-Aryl glutamine analogues as probes of the ASCT2 neutral amino acid transporter binding site Fulltext Access 8 Pages 2005
Selective interactions of perylene derivatives having different side chains with inter- and intramolecular G-quadruplex DNA structures. A correlation with telomerase inhibition Fulltext Access 8 Pages 2005
QSAR studies on structurally similar 2-(4-methanesulfonylphenyl)pyran-4-ones as selective COX-2 inhibitors: a Hansch approach Fulltext Access 8 Pages 2005
Novel pyrazinone mono-amides as potent and reversible caspase-3 inhibitors Fulltext Access 8 Pages 2005
QSAR studies on benzene sulfonamide carbonic anhydrase inhibitors: need of hydrophobic parameter for topological modeling of binding constants of sulfonamides to human CA-II Fulltext Access 8 Pages 2005
Identification and characterization of nonsubstrate based inhibitors of the essential dengue and West Nile virus proteases Fulltext Access 8 Pages 2005
New antiestrogens from a library screen of homoallylic amides, allylic amides, and C-cyclopropylalkylamides Fulltext Access 8 Pages 2005
Synthesis and photodynamic activity of zinc(II) phthalocyanine derivatives bearing methoxy and trifluoromethylbenzyloxy substituents in homogeneous and biological media Fulltext Access 8 Pages 2005
Classical and three-dimensional QSAR for the inhibition of [3H]ponasterone A binding by diacylhydrazine-type ecdysone agonists to insect Sf-9 cells Fulltext Access 8 Pages 2005
Formylchromone derivatives as irreversible and selective inhibitors of human protein tyrosine phosphatase 1B. Kinetic and modeling studies Fulltext Access 8 Pages 2005
NMR conformational analysis of p-tolyl furanopyrimidine 2â²-deoxyribonucleoside and crystal structure of its 3â²,5â²-di-O-acetyl derivative Fulltext Access 8 Pages 2005
Study on supramolecular complexing ability vis-à-vis estimation of pKa of substituted sulfonamides: Dominating role of Balaban index (J) Fulltext Access 8 Pages 2005
Structural Characterization of Lipoarabinomannans from Mycobacterium tuberculosis and Mycobacterium smegmatis by ESI Mass Spectrometry Fulltext Access 8 Pages 2005
Simultaneous Kinetic Characterization of Multiple Protein Forms by Top Down Mass Spectrometry Fulltext Access 8 Pages 2005
Determination of Affinity Constants and Response Factors of the Noncovalent Dimer of Gramicidin by Electrospray Ionization Mass Spectrometry and Mathematical Modeling Fulltext Access 8 Pages 2005
Structural Characterization of Sulfadiazine Metabolites Using H/D Exchange Combined with Various MS/MS Experiments Fulltext Access 8 Pages 2005
Shifts in protein charge state distributions with varying redox reagents in nanoelectrospray triple quadrupole mass spectrometry Fulltext Access 8 Pages 2005
Combined Ion-Mobility and Mass-Spectrometry Investigations of Metallothionein Complexes Using a Tandem Mass Spectrometer with a Segmented Second Quadrupole Fulltext Access 8 Pages 2005
Volumetric intensity dependence on the formation of molecular and atomic ions within a high intensity laser focus Fulltext Access 8 Pages 2005
LC-mass spectrometry analysis of N- and C-terminal boundary sequences of polypeptide fragments by limited proteolysis Fulltext Access 8 Pages 2005
Carbon nanotubes as adsorbent of solid-phase extraction and matrix for laser desorption/ionization mass spectrometry Fulltext Access 8 Pages 2005
Asymmetric version of P-S to P-C [1,3]-sigmatropic rearrangement in the ferrocene series Fulltext Access 8 Pages 2005
Synthesis of chromenochalcones and evaluation of their in vitro antileishmanial activity Fulltext Access 8 Pages 2005
Synthesis of some monocyclic analogues of mycophenolic acid via the Johnson ortho ester Claisen rearrangement Fulltext Access 8 Pages 2005
Synthesis and antitumor activity of 5-(9-acridinylamino)anisidine derivatives Fulltext Access 8 Pages 2005
Nitric oxide releasing derivatives of tolfenamic acid with anti-inflammatory activity and safe gastrointestinal profile Fulltext Access 8 Pages 2005
Oxidation of liposomal membrane suppressed by flavonoids: Quantitative structure-activity relationship Fulltext Access 8 Pages 2005
Functional studies on a ketoreductase gene from Streptomyces sp. AM-7161 to control the stereochemistry in medermycin biosynthesis Fulltext Access 8 Pages 2005
Design and synthesis of N-benzylpiperidine–purine derivatives as new dual inhibitors of acetyl- and butyrylcholinesterase Fulltext Access 8 Pages 2005
Tetra substituted thiophenes as anti-inflammatory agents: Exploitation of analogue-based drug design Fulltext Access 8 Pages 2005
Total synthesis of two novel brominated acetylenic diols (+)-diplyne C and E: stereoselective construction of the (E)-1-bromo-1-alkene Fulltext Access 8 Pages 2005
A highly enantioselective chemoenzymatic synthesis of syn-3-amino-2-hydroxy esters: key intermediates for taxol side chain and phenylnorstatine Fulltext Access 8 Pages 2005
Processing of cyclopropylarenes by toluene dioxygenase: isolation and absolute configuration of metabolites Fulltext Access 8 Pages 2005
Encapsulation of a chiral MnIII(salen) complex in ordered mesoporous silicas: an approach towards heterogenizing asymmetric epoxidation catalysts for non-functionalized alkenes Fulltext Access 8 Pages 2005
Coupled chemoenzymatic transfer hydrogenation catalysis for enantioselective reduction and oxidation reactions Fulltext Access 8 Pages 2005
Lipase-catalyzed enantiomeric separation of 1-aryloxy-3-thiocyanatopropan-2-ols: an attempt to prepare optically active thiiranes Fulltext Access 8 Pages 2005
Polymer-supported chiral phosphinooxazolidine ligands for palladium-catalyzed asymmetric allylic alkylations and Diels–Alder reactions Fulltext Access 8 Pages 2005
Influence of (S)-1-phenylethylamine para substitution on the resolution of (±)-1,4-benzodioxane-2-carboxylic acid: a crystallographic, theoretical and morphologic approach Fulltext Access 8 Pages 2005
Optically active P-chiral phosphinoselenoic amides: stereochemical outcome at the P-stereogenic center in the synthesis of these substances and their characterization Fulltext Access 8 Pages 2005
An effective approach to the enantiomers of alicyclic β-aminonitriles by using lipase catalysis Fulltext Access 8 Pages 2005
Ketoreductases: stereoselective catalysts for the facile synthesis of chiral alcohols Fulltext Access 8 Pages 2005
Asymmetric synthesis of 5,6-dehydrosenedigitalene using lipase-catalyzed highly enantioselective transesterification of a primary alcohol with vinyl 3-(4-trifluoromethylphenyl)propanoate Fulltext Access 8 Pages 2005
A study toward understanding the role of a phosphorus stereogenic center in (5S)-1,3-diaza-2-phospha-2-oxo-3-phenylbicyclo(3.3.0)octane derivatives as catalysts in the borane-mediated asymmetric reduction of prochiral ketones Fulltext Access 8 Pages 2005
New reagents for phosphatidylserine recognition and detection of apoptosis Fulltext Access 8 Pages 2005
Synthesis and in vitro cytotoxicity of novel hydrophilic chiral 2-alkoxy-1,4-butanediamine platinum (II) complexes Fulltext Access 8 Pages 2005
Analysis of structure–activity relationships for the ‘B-region’ of N-(4-t-butylbenzyl)-N′-[4-(methylsulfonylamino)benzyl]-thiourea analogues as TRPV1 antagonists Fulltext Access 8 Pages 2005
Comparison of positively charged DNG with DNA duplexes: a computational approach Fulltext Access 8 Pages 2005
Synthesis and preliminary biological evaluation of O6-[4-(2-[18F]fluoroethoxymethyl)benzyl]guanine as a novel potential PET probe for the DNA repair protein O6-alkylguanine-DNA alkyltransferase in cancer chemotherapy Fulltext Access 8 Pages 2005
Synthesis and pharmacological activities of some mononuclear Ru(II) complexes Fulltext Access 8 Pages 2005
Metabolism of pentacarboxylate porphyrinogens by highly purified human coproporphyrinogen oxidase: Further evidence for the existence of an abnormal pathway for heme biosynthesis Fulltext Access 8 Pages 2005
Synthesis and biological evaluation of new 4β-anilino- and 4β-imido-substituted podophyllotoxin congeners Fulltext Access 8 Pages 2005
‘O-Acyl isopeptide method’ for the efficient preparation of amyloid β peptide 1–42 mutants Fulltext Access 8 Pages 2005
Identification and characterization of small molecule modulators of KChIP/Kv4 function Fulltext Access 8 Pages 2005
Organic synthesis in pursuit of immunology: Large-scale synthesis of peracetylated GM2 glycosylamino acid for preparation of a multiantigenic prostate cancer vaccine Fulltext Access 8 Pages 2005
The solution structure of a lasalocid A metal complex in lipophilic solvents Fulltext Access 8 Pages 2005
Theoretical simulation of the electronic circular dichroism spectrum of calicheamicin Fulltext Access 8 Pages 2005
Comparison of different heterocyclic scaffolds as substrate analog PDE5 inhibitors Fulltext Access 8 Pages 2005
Modeling Km values using electrotopological state: Substrates for cytochrome P450 3A4-mediated metabolism Fulltext Access 9 Pages 2005
3,5-Bicyclic aryl piperidines: A novel class of α4β2 neuronal nicotinic receptor partial agonists for smoking cessation Fulltext Access 9 Pages 2005
Insecticidal anthranilic diamides: A new class of potent ryanodine receptor activators Fulltext Access 9 Pages 2005