Separation of chloroform from a dilute solution using a cyclic peptide nanotube: A molecular dynamics study Fulltext Access 42 Pages 2018
Development and applications of a physiologically-based model of paediatric oral drug absorption Fulltext Access 42 Pages 2018
Effects of hydrochlorothiazide and amlodipine on single oral dose pharmacokinetics of valsartan in healthy Korean subjects: Population model-based approach Fulltext Access 42 Pages 2018
Preclinical pharmacokinetics of benznidazole-loaded interpolyelectrolyte complex-based delivery systems Fulltext Access 42 Pages 2018
Manipulating the enone moiety of levoglucosenone: 1,3-Transposition reactions including ones leading to isolevoglucosenone Fulltext Access 42 Pages 2018
Structure-based design of allosteric calpain-1 inhibitors populating a novel bioactivity space Fulltext Access 42 Pages 2018
In silico design of small peptides antagonist against leptin receptor for the treatment of obesity and its associated immune-mediated diseases Fulltext Access 42 Pages 2018
Hemozoin inhibiting 2-phenylbenzimidazoles active against malaria parasites Fulltext Access 42 Pages 2018
Alignment-based and alignment-free methods converge with experimental data on amino acids coded by stop codons at split between nuclear and mitochondrial genetic codes Fulltext Access 43 Pages 2018
Update on the main use of biomaterials and techniques associated with tissue engineering Fulltext Access 43 Pages 2018
Characterizing eutectic mixtures of gliclazide with succinic acid prepared by electrospray deposition and liquid assisted grinding methods Fulltext Access 43 Pages 2018
Local low dose curcumin treatment improves functional recovery and remyelination in a rat model of sciatic nerve crush through inhibition of oxidative stress Fulltext Access 43 Pages 2018
Synthesis and characterization of dual responsive sodium alginate-g-acryloyl phenylalanine-poly N-isopropyl acrylamide smart hydrogels for the controlled release of anticancer drug Fulltext Access 43 Pages 2018
Design and development of an innovative water insoluble film-coating combination for oral pulsatile drug delivery Fulltext Access 43 Pages 2018
Podophyllotoxin derivatives as an excellent anticancer aspirant for future chemotherapy: A key current imminent needs Fulltext Access 43 Pages 2018
Peripheral modulation of the endocannabinoid system in metabolic disease Fulltext Access 43 Pages 2018
Brush border enzyme-cleavable linkers: Evaluation for reducing renal uptake of radiolabeled prostate-specific membrane antigen inhibitors Fulltext Access 43 Pages 2018
Design and biological activity of novel stealth polymeric lipid nanoparticles for enhanced delivery of hydrophobic photodynamic therapy drugs Fulltext Access 43 Pages 2018
A novel bio-inspired optimization model based on Yellow Saddle Goatfish behavior Fulltext Access 43 Pages 2018
Ophthalmic administration of a 10-fold-lower dose of conventional nanoliposome formulations caused levels of intraocular pressure similar to those induced by marketed eye drops Fulltext Access 43 Pages 2018
Synthesis and biological evaluation of novel 2-oxo-1,2-dihydroquinoline-4-carboxamide derivatives for the treatment of esophageal squamous cell carcinoma Fulltext Access 43 Pages 2018
Benzomorphan skeleton, a versatile scaffold for different targets: A comprehensive review Fulltext Access 43 Pages 2018
Synthesis of carbohydrazides and carboxamides as anti-tubercular agents Fulltext Access 43 Pages 2018
The role of lactose carrier on the powder behavior and aerodynamic performance of bosentan microparticles for dry powder inhalation Fulltext Access 43 Pages 2018
Novel drug delivery systems based on the encapsulation of superparamagnetic nanoparticles into lipid nanocomposites Fulltext Access 44 Pages 2018
Functional engineered mesenchymal stem cells with fibronectin-gold composite coated catheters for vascular tissue regeneration Fulltext Access 44 Pages 2018
Melt-electrospinning as a method to improve the dissolution and physical stability of a poorly water-soluble drug Fulltext Access 44 Pages 2018
Design of alpha mangostin-loaded chitosan/alginate controlled-release nanoparticles using genipin as crosslinker Fulltext Access 44 Pages 2018
Role of plasticizer in membrane coated extended release oral drug delivery system Fulltext Access 44 Pages 2018
Dual Therapeutic Effects of an Albumin-Based Nitric Oxide Donor on 2 Experimental Models of Chronic Kidney Disease Fulltext Access 44 Pages 2018
Neurological, sensorimotor and cardiorespiratory alterations induced by methoxetamine, ketamine and phencyclidine in mice Fulltext Access 44 Pages 2018
Design, synthesis, molecular docking of new lipophilic acetamide derivatives affording potential anticancer and antimicrobial agents Fulltext Access 44 Pages 2018
Design, synthesis, antimicrobial, antiquorum-sensing and antitumor evaluation of new series of pyrazolopyridine derivatives Fulltext Access 44 Pages 2018
The Repurposing of Ivermectin for Malaria: A Prospective Pharmacokinetics-Based Virtual Clinical Trials Assessment of Dosing Regimen Options Fulltext Access 44 Pages 2018
Influence of supramolecular layer-crosslinked structure on stability of dual pH-Responsive polymer nanoparticles for doxorubicin delivery Fulltext Access 45 Pages 2018
Reprecipitation of poorly water-soluble cilostazol crystals using adsorbing carriers for enhanced dissolution and physicochemical modification Fulltext Access 45 Pages 2018
Experimental optimization of Lornoxicam liposomes for sustained topical delivery Fulltext Access 45 Pages 2018
Formulation of 3D Printed Tablet for Rapid Drug Release by Fused Deposition Modeling: Screening Polymers for Drug Release, Drug-Polymer Miscibility and Printability Fulltext Access 45 Pages 2018
Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3 Fulltext Access 45 Pages 2018
An efficient computational fluid-particle dynamics method to predict deposition in a simplified approximation of the deep lung Fulltext Access 45 Pages 2018
CD44 directed nanomicellar payload delivery platform for selective anticancer effect and tumor specific imaging of triple negative breast cancer Fulltext Access 45 Pages 2018
Benzopyrroloxazines containing a bridgehead nitrogen atom as promising scaffolds for the achievement of biologically active agents Fulltext Access 45 Pages 2018
Novel Tacrine-Hydroxyphenylbenzimidazole hybrids as potential multitarget drug candidates for Alzheimer's disease Fulltext Access 45 Pages 2018
Increasing kynurenine brain levels reduces ethanol consumption in mice by inhibiting dopamine release in nucleus accumbens Fulltext Access 45 Pages 2018
Synthesis, anticancer activity and mechanism of action of new thiazole derivatives Fulltext Access 45 Pages 2018
Design, synthesis and biological evaluation of novel pyridine-thiazolidinone derivatives as anticancer agents: Targeting human carbonic anhydrase IX Fulltext Access 45 Pages 2018
Roflumilast promotes memory recovery and attenuates white matter injury in aged rats subjected to chronic cerebral hypoperfusion Fulltext Access 45 Pages 2018
Exposure to environmental enrichment attenuates addiction-like behavior and alters molecular effects of heroin self-administration in rats Fulltext Access 45 Pages 2018
From determination of enantiopurity to the construction of complex molecules: The Horeau principle and its application in synthesis Fulltext Access 45 Pages 2018
Facilitating the translation of nanomedicines to a clinical product: challenges and opportunities Fulltext Access 45 Pages 2018
Maladaptive behavioral regulation in alcohol dependence: Role of kappa-opioid receptors in the bed nucleus of the stria terminalis Fulltext Access 45 Pages 2018
Incomplete Loading of Sodium Lauryl Sulfate and Fasted State Simulated Intestinal Fluid Micelles Within the Diffusion Layers of Dispersed Drug Particles During Dissolution Fulltext Access 46 Pages 2018
Investigations on the Mechanism of Magnesium Stearate to Modify Aerosol Performance in Dry Powder Inhaled Formulations Fulltext Access 46 Pages 2018
Molecular hypotheses to explain the shared pathways and underlying pathobiological causes in catatonia and in catatonic presentations in neuropsychiatric disorders Fulltext Access 46 Pages 2018
Synthesis and mechanistic studies of quinolin-chlorobenzothioate derivatives with proteasome inhibitory activity in pancreatic cancer cell lines Fulltext Access 46 Pages 2018
Preparation of dual-drug conjugated polymeric micelles with synergistic anti-cancer efficacy in vitro Fulltext Access 46 Pages 2018
Alkylated resveratrol prodrugs and metabolites as potential therapeutics for neurodegenerative diseases Fulltext Access 46 Pages 2018
Design of two-tail compounds with rotationally fixed benzenesulfonamide ring as inhibitors of carbonic anhydrases Fulltext Access 46 Pages 2018
Functionalized extracellular vesicles as advanced therapeutic nanodelivery systems Fulltext Access 46 Pages 2018
Gold nanoparticles in injectable calcium phosphate cement enhance osteogenic differentiation of human dental pulp stem cells Fulltext Access 46 Pages 2018
Amino acid conjugated antimicrobial drugs: Synthesis, lipophilicity- activity relationship, antibacterial and urease inhibition activity Fulltext Access 47 Pages 2018
Targeting glycogen synthase kinase-3 for oxidative stress and neuroinflammation: Opportunities, challenges and future directions for cerebral stroke management Fulltext Access 47 Pages 2018
Synthesis, biological evaluation, and metabolic stability of phenazine derivatives as antibacterial agents Fulltext Access 47 Pages 2018
Synthesis and antibacterial evaluation of novel cationic chalcone derivatives possessing broad spectrum antibacterial activity Fulltext Access 47 Pages 2018
A minimalistic approach to develop new anti-apicomplexa polyamines analogs Fulltext Access 47 Pages 2018
Etoposide encapsulated functionalized mesoporous silica nanoparticles: Synthesis, characterization and effect of functionalization on dissolution kinetics in simulated and biorelevant media Fulltext Access 47 Pages 2018
Proteomic characterization of hippocampus of chronically socially isolated rats treated with fluoxetine: Depression-like behaviour and fluoxetine mechanism of action Fulltext Access 47 Pages 2018
Juvenile social defeat stress exposure persistently impairs social behaviors and neurogenesis Fulltext Access 47 Pages 2018
Modulation of quantum dots and clearance of Helicobacter pylori with synergy of cell autophagy Fulltext Access 48 Pages 2018
Antiplasmodial and antimalarial activities of quinolone derivatives: An overview Fulltext Access 48 Pages 2018
Design, synthesis and biological evaluation of hybrid nitroxide-based non-steroidal anti-inflammatory drugs Fulltext Access 48 Pages 2018
Facile synthesis of 1,2-dione-containing abietane analogues for the generation of human carboxylesterase inhibitors Fulltext Access 48 Pages 2018
Recent advances of imidazole-containing derivatives as anti-tubercular agents Fulltext Access 48 Pages 2018
Glutamine has antidepressive effects through increments of glutamate and glutamine levels and glutamatergic activity in the medial prefrontal cortex Fulltext Access 48 Pages 2018
Mechanisms of interaction of biodegradable polyester nanocapsules with non-phagocytic cells Fulltext Access 48 Pages 2018
Jietacins, azoxy antibiotics with potent nematocidal activity: Design, synthesis, and biological evaluation against parasitic nematodes Fulltext Access 48 Pages 2018
Polymeric bile acid sequestrants: Review of design, in vitro binding activities, and hypocholesterolemic effects Fulltext Access 48 Pages 2018
Glycogen synthase kinase-3 and its inhibitors: Potential target for various therapeutic conditions Fulltext Access 48 Pages 2018
Dissociable contributions of dorsal and ventral striatal regions on a rodent cost/benefit decision-making task requiring cognitive effort Fulltext Access 48 Pages 2018
Dose-reduction antiangiogenic curcumin-low molecular weight heparin nanodrugs for enhanced combinational antitumor therapy Fulltext Access 48 Pages 2018
Controlled-release biodegradable nanoparticles: From preparation to vaginal applications Fulltext Access 48 Pages 2018
Effect of poly(ethylene glycol) on insulin stability and cutaneous cell proliferation in vitro following cytoplasmic delivery of insulin-loaded nanoparticulate carriers - A potential topical wound management approach Fulltext Access 48 Pages 2018
Nanoencapsulation techniques for compounds and products with antioxidant and antimicrobial activity - A critical view Fulltext Access 49 Pages 2018
Influenza A virus polymerase: an attractive target for next-generation anti-influenza therapeutics Fulltext Access 49 Pages 2018
Hippocampal neural progenitor cells play a distinct role in fear memory retrieval in male and female CIE rats Fulltext Access 49 Pages 2018