Computational study of substituent effects on the acidity, toxicity and chemical reactivity of bacteriostatic sulfonamides Fulltext Access 35 Pages 2018
Synthesis and characterization of a photoaffinity labelling probe based on the structure of the cystic fibrosis drug ivacaftor Fulltext Access 35 Pages 2018
Rapid characterization of chemical markers for discrimination of Moutan Cortex and its processed products by direct injection-based mass spectrometry profiling and metabolomic method Fulltext Access 35 Pages 2018
Microglial-specific transcriptome changes following chronic alcohol consumption Fulltext Access 35 Pages 2018
Albumin-Encapsulated Liposomes: A Novel Drug Delivery Carrier With Hydrophobic Drugs Encapsulated in the Inner Aqueous Core Fulltext Access 35 Pages 2018
Powder Compression Properties of Paracetamol, Paracetamol Hydrochloride, and Paracetamol Cocrystals and Coformers Fulltext Access 35 Pages 2018
Cancer chemotherapy: Effect of poloxamer modified nanoparticles on cellular function Fulltext Access 35 Pages 2018
A novel quantification method for serine hydrolases in cellular expression system using fluorophosphonate-biotin probe Fulltext Access 35 Pages 2018
Ocular irritation and cyclosporine A distribution in the eye tissues after administration of Solid Lipid Microparticles in the rabbit model Fulltext Access 35 Pages 2018
Combined hyaluronate-based films loaded with pemetrexed and cisplatin for the treatment of malignant pleural mesothelioma: Preliminary evaluation in an orthotopic tumor recurrence model Fulltext Access 35 Pages 2018
Cocrystallization as a novel approach to enhance the transdermal administration of meloxicam Fulltext Access 35 Pages 2018
Synthesis and biological evaluation of pyridazinone derivatives as potential anti-inflammatory agents Fulltext Access 35 Pages 2018
Discovery of new erbB4 inhibitors: Repositioning an orphan chemical library by inverse virtual screening Fulltext Access 35 Pages 2018
Synthesis, crystal structure and antimicrobial potential of some fluorinated chalcone-1,2,3-triazole conjugates Fulltext Access 35 Pages 2018
A visible fluorescent nanovaccine based on functional genipin crosslinked ovalbumin protein nanoparticles Fulltext Access 35 Pages 2018
Structure of focal adhesion kinase in healthy heart versus pathological cardiac hypertrophy: A modeling and simulation study Fulltext Access 35 Pages 2018
A targeted ferritin-microplasmin based thrombolytic nanocage selectively dissolves blood clots Fulltext Access 35 Pages 2018
Temporally dissociable effects of ketamine on neuronal discharge and gamma oscillations in rat thalamo-cortical networks Fulltext Access 36 Pages 2018
Mixtures of betamethasone butyrate propionate ointments and heparinoid oil-based cream: Physical stability evaluation Fulltext Access 36 Pages 2018
Thrombolytic therapies for ischemic stroke: Triumphs and future challenges Fulltext Access 36 Pages 2018
Enhancing glioblastoma treatment using cisplatin-gold-nanoparticle conjugates and targeted delivery with magnetic resonance-guided focused ultrasound Fulltext Access 36 Pages 2018
Nanomagnetic-mediated drug delivery for the treatment of dental disease Fulltext Access 36 Pages 2018
Self-powered therapeutic release from conducting polymer/graphene oxide films on magnesium Fulltext Access 36 Pages 2018
Formation of graphene oxide-hybridized nanogels for combinative anticancer therapy Fulltext Access 36 Pages 2018
A continuous manufacturing concept for a pharmaceutical oral suspension Fulltext Access 36 Pages 2018
Structure-Function Relationships for Recombinant Erythropoietins: A Case Study From a Proposed Manufacturing Change With Implications for Erythropoietin Biosimilar Study Designs Fulltext Access 36 Pages 2018
Development and in vitro evaluation of chitosan based system for local delivery of atorvastatin for treatment of periodontitis Fulltext Access 36 Pages 2018
Impact of trial design on the estimation of drug potency and power in clinical trials of haemophilia with inhibitors Fulltext Access 36 Pages 2018
Systematic evaluation of common lubricants for optimal use in tablet formulation Fulltext Access 36 Pages 2018
In vitro lung epithelial cell transport and anti-interleukin-8 releasing activity of liposomal ciprofloxacin Fulltext Access 36 Pages 2018
The Solubility-Permeability Trade-Off of Progesterone With Cyclodextrins Under Physiological Conditions: Experimental Observations and Computer Simulations Fulltext Access 36 Pages 2018
Hybrid nanoparticle-based nicotine nanovaccines: Boosting the immunological efficacy by conjugation of potent carrier proteins Fulltext Access 36 Pages 2018
High frequency stimulation-induced plasticity in the prelimbic cortex of rats emerges during adolescent development and is associated with an increase in dopamine receptor function Fulltext Access 36 Pages 2018
Drug delivery system composed of mesoporous silica and hollow mesoporous silica nanospheres for chemotherapeutic drug delivery Fulltext Access 36 Pages 2018
Recent progress in the structural modification and pharmacological activities of ligustrazine derivatives Fulltext Access 36 Pages 2018
Effect of Ginkgo biloba extract-761 on motor functions in permanent middle cerebral artery occlusion rats Fulltext Access 36 Pages 2018
Synthesis and anticancer activity evaluation of novel azacalix[2]arene[2]pyrimidines Fulltext Access 36 Pages 2018
Modeling of decision-making process for moving straight using inverse Bayesian inference Fulltext Access 36 Pages 2018
Synthesis, molecular modeling studies and evaluation of antifungal activity of a novel series of thiazole derivatives Fulltext Access 36 Pages 2018
Leukocytes and drug-resistant cancer cells are targets for intracellular delivery by adenoviral dodecahedron Fulltext Access 36 Pages 2018
Rescue of glutamate transport in the lateral habenula alleviates depression- and anxiety-like behaviors in ethanol-withdrawn rats Fulltext Access 36 Pages 2018
Synthesis and biological evaluation of new water-soluble photoactive chlorin conjugate for targeted delivery Fulltext Access 36 Pages 2018
Mycobacterial siderophore: A review on chemistry and biology of siderophore and its potential as a target for tuberculosis Fulltext Access 36 Pages 2018
Rational modification of a lead molecule: Improving the antifungal activity of indole - triazole - amino acid conjugates Fulltext Access 36 Pages 2018
Atypical dopamine transporter inhibitors attenuate compulsive-like methamphetamine self-administration in rats Fulltext Access 36 Pages 2018
Novel 1,2,4-triazole derivatives as potential anticancer agents: Design, synthesis, molecular docking and mechanistic studies Fulltext Access 36 Pages 2018
Design, synthesis and evaluation of amino-substituted 1H-phenalen-1-ones as anti-leishmanial agents Fulltext Access 36 Pages 2018
New pyrazolopyridine analogs: Synthesis, antimicrobial, antiquorum-sensing and antitumor screening Fulltext Access 36 Pages 2018
Discussions on the hepatic well-stirred model: Re-derivation from the dispersion model and re-analysis of the lidocaine data Fulltext Access 37 Pages 2018
Mechanics of Pharmaceutical Pellets-Constitutive Properties, Deformation, and Breakage Behavior Fulltext Access 37 Pages 2018
Amphetamine improves mouse and human attention in the 5-choice continuous performance test Fulltext Access 37 Pages 2018
Influence of Niobium Pentoxide Particulates on the Properties of Brushite/Gelatin/Alginate Membranes Fulltext Access 37 Pages 2018
Sustained release of herbal drugs using biodegradable scaffold for faster wound healing and better patient compliance Fulltext Access 37 Pages 2018
Producing Amorphous Solid Dispersions via Co-Precipitation and Spray Drying: Impact to Physicochemical and Biopharmaceutical Properties Fulltext Access 37 Pages 2018
Importance of kynurenine 3-monooxygenase for spontaneous firing and pharmacological responses of midbrain dopamine neurons: Relevance for schizophrenia Fulltext Access 37 Pages 2018
Fear extinction in an obsessive-compulsive disorder animal model: Influence of sex and estrous cycle Fulltext Access 37 Pages 2018
Derivatization of honokiol by integrated acetylation and methylation for improved cutaneous delivery and anti-inflammatory potency Fulltext Access 37 Pages 2018
Corticosterone impairs gap junctions in the prefrontal cortical and hippocampal astrocytes via different mechanisms Fulltext Access 37 Pages 2018
Polymer-lipid hybrid nanoparticles as enhanced indomethacin delivery systems Fulltext Access 37 Pages 2018
Synthesis and antiproliferative activity of podocarpane and totarane derivatives Fulltext Access 37 Pages 2018
Microwave-assisted one-pot synthesis of new phenanthrene fused-tetrahydrodibenzo-acridinones as potential cytotoxic and apoptosis inducing agents Fulltext Access 37 Pages 2018
Investigating isoindoline, tetrahydroisoquinoline, and tetrahydrobenzazepine scaffolds for their sigma receptor binding properties Fulltext Access 37 Pages 2018
Synthesis of novel ring-contracted artemisinin dimers with potent anticancer activities Fulltext Access 37 Pages 2018
Design and synthesis of novel quinacrine-[1,3]-thiazinan-4-one hybrids for their anti-breast cancer activity Fulltext Access 37 Pages 2018
A routinely used protein staining dye acts as an inhibitor of wild type and mutant alpha-synuclein aggregation and modulator of neurotoxicity Fulltext Access 37 Pages 2018
Computational morphogenesis - Embryogenesis, cancer research and digital pathology Fulltext Access 37 Pages 2018
Effect of laser fluence, nanoparticle concentration and total energy input per cell on photoporation of cells Fulltext Access 37 Pages 2018
Study of the influence of substrate and spectrophotometer characteristics on the in vitro measurement of sunscreens efficiency Fulltext Access 37 Pages 2018
Effect of milling on the plastic and the elastic stiffness of lactose particles Fulltext Access 37 Pages 2018
Proteomics of human liver membrane transporters: a focus on fetuses and newborn infants Fulltext Access 37 Pages 2018
Real-time monitoring of the tablet-coating process by near-infrared spectroscopy - Effects of coating polymer concentrations on pharmaceutical properties of tablets Fulltext Access 37 Pages 2018
Gadolinium nanoparticles as diagnostic and therapeutic agents: Their delivery systems in magnetic resonance imaging and neutron capture therapy Fulltext Access 37 Pages 2018
Discovery and synthesis of novel magnolol derivatives with potent anticancer activity in non-small cell lung cancer Fulltext Access 37 Pages 2018
Regulation of monocyte redox balance by 1,8-cineole (eucalyptol) controls oxidative stress and pro-inflammatory responses in vitro: A new option to increase the antioxidant effects of combined respiratory therapy with budesonide and formoterol? Fulltext Access 38 Pages 2018
In silico insight into voltage-gated sodium channel 1.7 inhibition for anti-pain drug discovery Fulltext Access 38 Pages 2018
Preparation, characterization and pharmacokinetics of extended-release tablets of marine polysaccharide drug Fulltext Access 38 Pages 2018
Antibacterial and antioxidant activities for natural and synthetic dual-active compounds Fulltext Access 38 Pages 2018
Novelty enhances memory persistence and remediates propranolol-induced deficit via reconsolidation Fulltext Access 38 Pages 2018
Early life stress determines the effects of glucocorticoids and stress on hippocampal function: Electrophysiological and behavioral evidence respectively Fulltext Access 38 Pages 2018
An eco-friendly catalytic system for multicomponent, one-pot synthesis of novel spiro-chromeno indoline-triones and their anti-prostate cancer potentials evaluated via alkaline phosphatase inhibition mechanism Fulltext Access 38 Pages 2018
Synthesis and biological evaluation of coumarin derivatives containing imidazole skeleton as potential antibacterial agents Fulltext Access 38 Pages 2018
Bioequivalence of topical generic products. Part 2. Paving the way to a tailored regulatory system Fulltext Access 38 Pages 2018
Optimization of nanostructured lipid carriers for Zidovudine delivery using a microwave-assisted production method Fulltext Access 38 Pages 2018
Pharmacokinetic and pharmaceutical properties of a novel buprenorphine/naloxone sublingual tablet for opioid substitution therapy versus conventional buprenorphine/naloxone sublingual tablet in healthy volunteers Fulltext Access 38 Pages 2018
Immunological effects of iron oxide nanoparticles and iron-based complex drug formulations: Therapeutic benefits, toxicity, mechanistic insights, and translational considerations Fulltext Access 38 Pages 2018
Effects of two droplet-based dissolving microneedle manufacturing methods on the activity of encapsulated epidermal growth factor and ascorbic acid Fulltext Access 38 Pages 2018
Topical Application of Keratinocyte Growth Factor Conjugated Gold Nanoparticles Accelerate Wound Healing Fulltext Access 38 Pages 2018
The Synergetic Effects of Nonpolar and Polar Protic Solvents on the Properties of Felodipine and Soluplus in Solutions, Casting Films, and Spray-Dried Solid Dispersions Fulltext Access 38 Pages 2018
Investigation of Ethylene Oxide-co-propylene Oxide for Dissolution Enhancement of Hot-Melt Extruded Solid Dispersions Fulltext Access 38 Pages 2018
Cognitive dysfunction and metabolic comorbidities in mood disorders: A repurposing opportunity for glucagon-like peptide 1 receptor agonists? Fulltext Access 38 Pages 2018
Protracted motivational dopamine-related deficits following adolescence sugar overconsumption Fulltext Access 38 Pages 2018
Discovery of potent and novel smoothened antagonists via structure-based virtual screening and biological assays Fulltext Access 39 Pages 2018