Do co-spray dried excipients offer better lysozyme stabilisation than single excipients? Fulltext Access 12 Pages 2008
Polyurethane Intravaginal Ring for Controlled Delivery of Dapivirine, a Nonnucleoside Reverse Transcriptase Inhibitor of HIV-1 Fulltext Access 12 Pages 2008
Development and pharmacological evaluation of ropivacaine-2-hydroxypropyl-β-cyclodextrin inclusion complex Fulltext Access 12 Pages 2008
A new principal component analysis-based approach for testing “similarity” of drug dissolution profiles Fulltext Access 12 Pages 2008
Copper ion-mediated liposomal encapsulation of mitoxantrone: The role of anions in drug loading, retention and release Fulltext Access 12 Pages 2008
Amine-reactive pyridylhydrazone-based PEG reagents for pH-reversible PEI polyplex shielding Fulltext Access 12 Pages 2008
Formation of hydrogen-bonded complexes between bile acids and lidocaine in the lidocaine transfer from an aqueous phase to chloroform Fulltext Access 12 Pages 2008
Thermosensitive polymer-conjugated albumin nanospheres as thermal targeting anti-cancer drug carrier Fulltext Access 12 Pages 2008
Interaction of mitoxantrone with human serum albumin: Spectroscopic and molecular modeling studies Fulltext Access 12 Pages 2008
In Vitro Phototoxic Potential and Photochemical Properties of Imidazopyridine Derivative: A Novel 5-HT4 Partial Agonist Fulltext Access 12 Pages 2008
Preparation of sustained release co-extrudates by hot-melt extrusion and mathematical modelling of in vitro/in vivo drug release profiles Fulltext Access 12 Pages 2008
Modulation of breast cancer resistance protein (BCRP/ABCG2) by non-basic chalcone analogues Fulltext Access 12 Pages 2008
Role of the microenvironment in tumor growth and in refractoriness/resistance to anti-angiogenic therapies Fulltext Access 12 Pages 2008
In-silico model of skin penetration based on experimentally determined input parameters. Part II: Mathematical modelling of in-vitro diffusion experiments. Identification of critical input parameters Fulltext Access 12 Pages 2008
Cell line-dependent internalization pathways and intracellular trafficking determine transfection efficiency of nanoparticle vectors Fulltext Access 12 Pages 2008
Comparison of salmeterol xinafoate microparticle production by conventional and novel antisolvent crystallization Fulltext Access 12 Pages 2008
Two-Scale, Three-Phase Theory for Swelling Drug Delivery Systems. Part II: Flow and Transport Models Fulltext Access 12 Pages 2008
Development and validation of the patient trust in community pharmacists (TRUST-Ph) scale: Results from a study conducted in Thailand Fulltext Access 12 Pages 2008
Medical Expenditure Panel Survey: A valuable database for studying racial and ethnic disparities in prescription drug use Fulltext Access 12 Pages 2008
Patients' views on the UK policy of prescription charges-Insights from qualitative interviews Fulltext Access 12 Pages 2008
Comparing 4 classification systems for drug-related problems: Processes and functions Fulltext Access 12 Pages 2008
Transplacental exposure to the vacuolar-ATPase inhibitor bafilomycin disrupts survival signaling in β cells and delays neonatal remodeling of the endocrine pancreas Fulltext Access 12 Pages 2008
Alteration of fertility endpoints in adult male F-344 rats by subchronic exposure to inhaled benzo(a)pyrene Fulltext Access 12 Pages 2008
Statistical analysis of in vitro data for risk assessment – Exemplified for a case of Ames test data Fulltext Access 12 Pages 2008
Protective effects of Angelica sinensis extract on amyloid β-peptide-induced neurotoxicity Fulltext Access 12 Pages 2008
Metabolic Bioactivation and Toxicity of Ethyl 4-Hydroxybenzoate in Human SK-MEL-28 Melanoma Cells Fulltext Access 12 Pages 2008
Charged nanoparticles as protein delivery systems: A feasibility study using lysozyme as model protein Fulltext Access 12 Pages 2008
Measurement of Surface pH of Pharmaceutical Solids: A Critical Evaluation of Indicator Dye-Sorption Method and its Comparison With Slurry pH Method Fulltext Access 12 Pages 2008
Effects of Solution Conditions, Processing Parameters, and Container Materials on Aggregation of a Monoclonal Antibody during Freeze-Thawing Fulltext Access 12 Pages 2008
The Development of Heated Tip Force-Distance Measurements as a Novel Approach to Site-Specific Characterization of Pharmaceutical Materials Fulltext Access 12 Pages 2008
Cytotoxicity and Apoptosis Enhancement in Brain Tumor Cells Upon Coadministration of Paclitaxel and Ceramide in Nanoemulsion Formulations Fulltext Access 12 Pages 2008
Studies on the Crystal forms of Pefloxacin: Preparation, Characterization, and Dissolution Profile Fulltext Access 12 Pages 2008
Complexation Hydrogels for Oral Insulin Delivery: Effects of Polymer Dosing on in Vivo Efficacy Fulltext Access 12 Pages 2008
Structural, Thermodynamic, and Kinetic Aspectsof the Trimorphism of Hydrocortisone Fulltext Access 12 Pages 2008
In Situ Monitoring of Polymorph Transformation of Clopidogrel Hydrogen Sulfate Using Measurement of Ultrasonic Velocity Fulltext Access 12 Pages 2008
Determination of Outer Layer and Bulk Dehydration Kinetics of Trehalose Dihydrate Using Atomic Force Microscopy, Gravimetric Vapour Sorption and Near Infrared Spectroscopy Fulltext Access 12 Pages 2008
Physicochemical Characterization and Membrane Binding Properties of Camptothecin Fulltext Access 12 Pages 2008
Direct Control of Drug Release Behavior from Layered Double Hydroxides through Particle Interactions Fulltext Access 12 Pages 2008
Inhibition of immune complex-mediated neutrophil oxidative metabolism: A pharmacophore model for 3-phenylcoumarin derivatives using GRIND-based 3D-QSAR and 2D-QSAR procedures Fulltext Access 12 Pages 2008
Synthesis of some novel thiourea derivatives obtained from 5-[(4-aminophenoxy)methyl]-4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thiones and evaluation as antiviral/anti-HIV and anti-tuberculosis agents Fulltext Access 12 Pages 2008
Synthesis and biochemical evaluation of guanidino-alkyl-ribitol derivatives as nucleoside hydrolase inhibitors Fulltext Access 12 Pages 2008
In silico prediction of brain and CSF permeation of small molecules using PLS regression models Fulltext Access 12 Pages 2008
Class II-selective histone deacetylase inhibitors. Part 2: Alignment-independent GRIND 3-D QSAR, homology and docking studies Fulltext Access 12 Pages 2008
Computational aqueous solubility prediction for drug-like compounds in congeneric series Fulltext Access 12 Pages 2008
An efficient tool for identifying inhibitors based on 3D-QSAR and docking using feature-shape pharmacophore of biologically active conformation – A case study with CDK2/CyclinA Fulltext Access 12 Pages 2008
Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo[3,4-d]pyrimidines Fulltext Access 12 Pages 2008
Rational design, synthesis and biological evaluation of new 1,5-diarylpyrazole derivatives as CB1 receptor antagonists, structurally related to rimonabant Fulltext Access 12 Pages 2008
Binding mode analysis and enrichment studies on homology models of the human histamine H4 receptor Fulltext Access 12 Pages 2008
Exploring molecular shape analysis of styrylquinoline derivatives as HIV-1 integrase inhibitors Fulltext Access 12 Pages 2008
QSAR, action mechanism and molecular design of flavone and isoflavone derivatives with cytotoxicity against HeLa Fulltext Access 12 Pages 2008
Structural insights into the Plasmodium falciparum histone deacetylase 1 (PfHDAC-1): A novel target for the development of antimalarial therapy Fulltext Access 12 Pages 2008
Design, synthesis and trypanocidal activity of lead compounds based on inhibitors of parasite glycolysis Fulltext Access 12 Pages 2008
Synthesis, cytotoxic activity, and SAR analysis of the derivatives of taxchinin A and brevifoliol Fulltext Access 12 Pages 2008
7-Aryl 1,5-dihydro-benzo[e][1,4]oxazepin-2-ones and analogs as non-steroidal progesterone receptor antagonists Fulltext Access 12 Pages 2008
Exploring the substituent effects on a novel series of C1′-dimethyl-aryl Δ8-tetrahydrocannabinol analogs Fulltext Access 12 Pages 2008
Quantitative determination of cesium binding to ferric hexacyanoferrate: Prussian blue Fulltext Access 12 Pages 2008
Metabolism pathway of vinorelbine (Navelbine®) in human: Characterisation of the metabolites by HPLC–MS/MS Fulltext Access 12 Pages 2008
Guidelines on good clinical laboratory practice: Bridging operations between research and clinical research laboratories Fulltext Access 12 Pages 2008
Structural elucidation of in vitro and in vivo metabolites of cryptotanshinone by HPLC–DAD–ESI–MSn Fulltext Access 12 Pages 2008
In vitro–in vivo correlations of self-emulsifying drug delivery systems combining the dynamic lipolysis model and neuro-fuzzy networks Fulltext Access 12 Pages 2008
Raman and thermal analysis of indomethacin/PVP solid dispersion enteric microparticles Fulltext Access 12 Pages 2008
Influence of crystal hydration on the mechanical properties of sodium naproxen Fulltext Access 12 Pages 2008
The influence of cationic lipid type on in-vitro release kinetic profiles of antisense oligonucleotide from cationic nanoemulsions Fulltext Access 12 Pages 2008
Effect of formulation parameters on 2-methoxyestradiol release from injectable cylindrical poly(dl-lactide-co-glycolide) implants Fulltext Access 12 Pages 2008
Liposomal vasoactive intestinal peptide for lung application: Protection from proteolytic degradation Fulltext Access 12 Pages 2008
Novel cationic liposome formulation for the delivery of an oligonucleotide decoy to NF-κB into activated macrophages Fulltext Access 12 Pages 2008
Bi-layered self-emulsifying pellets prepared by co-extrusion and spheronization: Influence of formulation variables and preliminary study on the in vivo absorption Fulltext Access 12 Pages 2008
An investigation into the relationship between carrier-based dry powder inhalation performance and formulation cohesive–adhesive force balances Fulltext Access 12 Pages 2008
Preparation, characterization and in vivo evaluation of amorphous atorvastatin calcium nanoparticles using supercritical antisolvent (SAS) process Fulltext Access 12 Pages 2008
Immune response by nasal delivery of hepatitis B surface antigen and codelivery of a CpG ODN in alginate coated chitosan nanoparticles Fulltext Access 12 Pages 2008
Modulation of gel formation and drug-release characteristics of lidocaine-loaded poly(vinyl alcohol)-tetraborate hydrogel systems using scavenger polyol sugars Fulltext Access 12 Pages 2008
Development of novel polymeric micellar drug conjugates and nano-containers with hydrolyzable core structure for doxorubicin delivery Fulltext Access 12 Pages 2008
Harmonization of strategies for the validation of quantitative analytical procedures: A SFSTP proposal: Part IV. Examples of application Fulltext Access 12 Pages 2008
Supercritical fluid technologies: An innovative approach for manipulating the solid-state of pharmaceuticals Fulltext Access 12 Pages 2008
Micronization processes with supercritical fluids: Fundamentals and mechanisms Fulltext Access 12 Pages 2008
Realizing the potential of the Actinium-225 radionuclide generator in targeted alpha particle therapy applications Fulltext Access 12 Pages 2008
Active targeting schemes for nanoparticle systems in cancer therapeutics Fulltext Access 12 Pages 2008
Overcoming the formulation obstacles towards targeted chemotherapy: In vitro and in vivo evaluation of cytotoxic drug loaded immunonanoparticles Fulltext Access 12 Pages 2008
Chemoenzymatic synthesis and antimicrobial activity evaluation of monogalactosyl diglycerides Fulltext Access 12 Pages 2008