Atomizing into a Chilled Extraction Solvent Eliminates Liquid Gas from a Spray-Freeze Drying Microencapsulation Process Fulltext Access 14 Pages 2008
Comparison of Delivery Characteristics from a Combination Metered-Dose Inhaler Using the Andersen Cascade Impactor and the Next Generation Pharmaceutical Impactor Fulltext Access 14 Pages 2008
Biodegradable Films Developed by Electrospray Deposition for Sustained Drug Delivery Fulltext Access 14 Pages 2008
Alternative Drug Delivery Approaches for the Therapy of Inflammatory Bowel Disease Fulltext Access 14 Pages 2008
Evaluation of human nasal RPMI 2650 cells grown at an air-liquid interface as a model for nasal drug transport studies Fulltext Access 14 Pages 2008
Increased Paracellular Absorption by Bile Salts and P-Glycoprotein Stimulated Efflux of Otilonium Bromide in Caco-2 Cells Monolayers as a Model of Intestinal Barrier Fulltext Access 14 Pages 2008
Extent and Mechanism of Solvation and Partitioning of Isomers of Substituted Benzoic Acids: A Thermodynamic Study in the Solid State and in Solution Fulltext Access 14 Pages 2008
Conformation and Side Chains Environments of Recombinant Human Interleukin-1 Receptor Antagonist (rh-IL-1ra) Probed by Raman, Raman Optical Activity, and UV-Resonance Raman Spectroscopy Fulltext Access 14 Pages 2008
Effect Of Structural Relaxation On The Preparation And Drug Release Behavior Of Poly(lactic-co-glycolic)acid Microparticle Drug Delivery Systems Fulltext Access 14 Pages 2008
Noncovalent PEGylation: Different Effects of Dansyl-, l-Tryptophan-, Phenylbutylamino-, Benzyl- and Cholesteryl-PEGs on the Aggregation of Salmon Calcitonin and Lysozyme Fulltext Access 14 Pages 2008
A Laser Imaging and Neutron Reflection Investigation Into the Monolayer Behaviour of Fatty Acids Used for Taste Masking Microspheres Fulltext Access 14 Pages 2008
Formulating Poly(Lactide-Co-Glycolide) Particles for Plasmid DNA Delivery Fulltext Access 14 Pages 2008
Dimethoxyaurones: Potent inhibitors of ABCG2 (breast cancer resistance protein) Fulltext Access 14 Pages 2008
Comparison of drug transporter gene expression and functionality in Caco-2 cells from 10 different laboratories Fulltext Access 14 Pages 2008
Study of protein conformational stability and integrity using calorimetry and FT-Raman spectroscopy correlated with enzymatic activity Fulltext Access 14 Pages 2008
Role of mTOR in anticancer drug resistance: Perspectives for improved drug treatment Fulltext Access 14 Pages 2008
Development of HSA-free formulations for a hydrophobic cytokine with improved stability Fulltext Access 14 Pages 2008
Supercritical fluid drying of carbohydrates: Selection of suitable excipients and process conditions Fulltext Access 14 Pages 2008
Chitosan coated Ca–alginate microparticles loaded with budesonide for delivery to the inflamed colonic mucosa Fulltext Access 14 Pages 2008
Older adults' drug benefit beliefs: construct definition and measure development Fulltext Access 14 Pages 2008
Utilization, price, and spending trends for antidepressants in the US Medicaid program Fulltext Access 14 Pages 2008
Sulfonamides as a subject to study molecular interactions in crystals and solutions: Sublimation, solubility, solvation, distribution and crystal structure Fulltext Access 14 Pages 2008
S-Propranolol imprinted polymer nanoparticle-on-microsphere composite porous cellulose membrane for the enantioselectively controlled delivery of racemic propranolol Fulltext Access 14 Pages 2008
Linker-based lecithin microemulsions for transdermal delivery of lidocaine Fulltext Access 14 Pages 2008
An ionically crosslinked hydrogel containing vancomycin coating on a porous scaffold for drug delivery and cell culture Fulltext Access 14 Pages 2008
Size analysis of submicron particles by laser diffractometry—90% of the published measurements are false Fulltext Access 14 Pages 2008
The rheological properties of pharmaceutical foam: Implications for use Fulltext Access 14 Pages 2008
Physico-mechanical analysis of free ethyl cellulose films comprised with novel plasticizers of vitamin resources Fulltext Access 14 Pages 2008
Microencapsulation by solvent evaporation: State of the art for process engineering approaches Fulltext Access 14 Pages 2008
Synergism between natural products and antibiotics against infectious diseases Fulltext Access 14 Pages 2008
Extracts of Valeriana officinalis L. s.l. show anxiolytic and antidepressant effects but neither sedative nor myorelaxant properties Fulltext Access 14 Pages 2008
Effect of Centella asiatica leaf powder on oxidative markers in brain regions of prepubertal mice in vivo and its in vitro efficacy to ameliorate 3-NPA-induced oxidative stress in mitochondria Fulltext Access 14 Pages 2008
In Vivo comparative study of lipid/DNA complexes with different In Vitro serum stability: Effects on biodistribution and tumor accumulation Fulltext Access 14 Pages 2008
Metabolism and Disposition of Resveratrol in the Isolated Perfused Rat Liver: Role of Mrp2 in the Biliary Excretion of Glucuronides Fulltext Access 14 Pages 2008
Examination of Barriers and Barrier Alteration in Transscleral Iontophoresis Fulltext Access 14 Pages 2008
Variability in Caco-2 and MDCK Cell-Based Intestinal Permeability Assays Fulltext Access 14 Pages 2008
Influence of polymeric excipients on crystal hydrate formation kinetics in aqueous slurries Fulltext Access 14 Pages 2008
Synthesis and cytotoxicity evaluation of 22,23-oxygenated stigmastane derivatives Fulltext Access 14 Pages 2008
Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine α-hydroxylating monooxygenase (PHM) Fulltext Access 14 Pages 2008
Synthesis and structure–activity relationships for biphenyl H3 receptor antagonists with moderate anti-cholinesterase activity Fulltext Access 14 Pages 2008
Synthesis of indirubin-N′-glycosides and their anti-proliferative activity against human cancer cell lines Fulltext Access 14 Pages 2008
Structure–activity relationship studies of imidazo[1,2-c]pyrimidine derivatives as potent and orally effective Syk family kinases inhibitors Fulltext Access 14 Pages 2008
Design, synthesis, and structure–activity relationship of novel opioid κ-agonists Fulltext Access 14 Pages 2008
(3S)-N-(l-Aminoacyl)-1,2,3,4-tetrahydroisoquinolines, a class of novel antithrombotic agents: Synthesis, bioassay, 3D QSAR, and ADME analysis Fulltext Access 14 Pages 2008
Design, synthesis, and evaluation of potential inhibitors of nitric oxide synthase Fulltext Access 14 Pages 2008
Design and synthesis of benzenesulfonanilides active against methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus Fulltext Access 14 Pages 2008
Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists Fulltext Access 14 Pages 2008
Synthesis of both enantiomers of hydroxypipecolic acid derivatives equivalent to 5-azapyranuronic acids and evaluation of their inhibitory activities against glycosidases Fulltext Access 14 Pages 2008
Synthesis, antimalarial activity, structure-activity relationship analysis of thieno-[3,2-b]benzothiazine S,S-dioxide analogs Fulltext Access 14 Pages 2008
Benzenesulfonamide indole inhibitors of cytosolic phospholipase A2α: Optimization of in vitro potency and rat pharmacokinetics for oral efficacy Fulltext Access 14 Pages 2008
Imine derivatives as new potent and selective CB2 cannabinoid receptor agonists with an analgesic action Fulltext Access 14 Pages 2008
Selective alkylation of βII-tubulin and thioredoxin-1 by structurally related subsets of aryl chloroethylureas leading to either anti-microtubules or redox modulating agents Fulltext Access 14 Pages 2008
Pyrazino[1,2-b]isoquinolines: Synthesis and study of their cytostatic and cytotoxic properties Fulltext Access 14 Pages 2008
Specific targeting of metzincin family members with small-molecule inhibitors: Progress toward a multifarious challenge Fulltext Access 14 Pages 2008
Structure–activity relationship studies of a new series of imidazo[2,1-f]purinones as potent and selective A3 adenosine receptor antagonists Fulltext Access 14 Pages 2008
Analysis of the constituents in the rat plasma after oral administration of Yin Chen Hao Tang by UPLC/Q-TOF-MS/MS Fulltext Access 14 Pages 2008
Influence of the polymerization-mixture composition for monolithic methacrylate-based columns on the electrochromatographic performance of drug molecules Fulltext Access 14 Pages 2008
Development of microporous drug-releasing films cast from artificial nanosized latexes of poly(styrene-co-methyl methacrylate) or poly(styrene-co-ethyl methacrylate) Fulltext Access 14 Pages 2008
Exploring the use of novel drug delivery systems for antiretroviral drugs Fulltext Access 14 Pages 2008
Application of supercritical fluid to preparation of powders of high-molecular weight drugs for inhalation Fulltext Access 14 Pages 2008
Antibody tumor penetration: Transport opposed by systemic and antigen-mediated clearance Fulltext Access 14 Pages 2008
Use of antibodies and immunoconjugates for the therapy of more accessible cancers Fulltext Access 14 Pages 2008
Determination of bisphosphonate active pharmaceutical ingredients in pharmaceuticals and biological material: A review of analytical methods Fulltext Access 14 Pages 2008
Cyclic nucleotide phosphodiesterase type 4 inhibitors: Evaluation of pyrazolo[1,5-a]-1,3,5-triazine ring system as an adenine bioisostere Fulltext Access 14 Pages 2008
3D-QSAR studies of Checkpoint Kinase Weel inhibitors based on molecular docking, CoMFA and CoMSIA Fulltext Access 14 Pages 2008
Antitumor studies – Part 2: Structure–activity relationship study for flavin analogs including investigations on their in vitro antitumor assay and docking simulation into protein tyrosine kinase Fulltext Access 14 Pages 2008
Synthesis and biological evaluation of pyrazoline analogues with β-amino acyl group as dipeptidyl peptidase IV inhibitors Fulltext Access 14 Pages 2008
Active core structure of terfestatin A, a new specific inhibitor of auxin signaling Fulltext Access 14 Pages 2008
Synthesis and structure–activity relationships of potent 4-fluoro-2-cyanopyrrolidine dipeptidyl peptidase IV inhibitors Fulltext Access 14 Pages 2008
Selective plasma protein binding of antimalarial drugs to α1-acid glycoprotein Fulltext Access 14 Pages 2008