Ocular transport model for ophthalmic delivery of timolol through p-HEMA contact lenses Fulltext Access 11 Pages 2007
Influence of polymer behaviour in organic solution on the production of polylactide nanoparticles by nanoprecipitation Fulltext Access 11 Pages 2007
Rate-modulating PHBHV/PCL microparticles containing weak acid model drugs Fulltext Access 11 Pages 2007
5-ASA loaded chitosan–Ca–alginate microparticles: Preparation and physicochemical characterization Fulltext Access 11 Pages 2007
Oxidative stress induced by fluoride in adult mice and their suckling pups Fulltext Access 11 Pages 2007
Potential osteogenic differentiation of cisplatin-resistant rat malignant fibrous histiocytoma-derived cell lines Fulltext Access 11 Pages 2007
Diazinon toxicity affects histophysiological and biochemical parameters in rabbits Fulltext Access 11 Pages 2007
Toxicological evaluation of cigarettes with two banded cigarette paper technologies Fulltext Access 11 Pages 2007
DNA ploidy distribution in renal tumours induced in male rats by dietary ochratoxin A Fulltext Access 11 Pages 2007
Expression of mRNAs related to connective tissue metabolism in rat hepatic stellate cells and myofibroblasts Fulltext Access 11 Pages 2007
Bioassay by intratracheal instillation for detection of lung toxicity due to fine particles in F344 male rats Fulltext Access 11 Pages 2007
Subtype-specific activation of estrogen receptors by a special extract of Rheum rhaponticum (ERr 731®), its aglycones and structurally related compounds in U2OS human osteosarcoma cells Fulltext Access 11 Pages 2007
Stabilized Amorphous State of Ibuprofen by CoâSpray Drying With Mesoporous SBAâ15 to Enhance Dissolution Properties Fulltext Access 11 Pages 2007
Synthesis and in vitro evaluation of thiolated hyaluronic acid for mucoadhesive drug delivery Fulltext Access 11 Pages 2007
Screening for differences in the amorphous state of indomethacin using multivariate visualization Fulltext Access 11 Pages 2007
Rat epidermal keratinocyte organotypic culture (ROC) compared to human cadaver skin: The effect of skin permeation enhancers Fulltext Access 11 Pages 2007
Interaction of macrocyclic lactones with P-glycoprotein: Structure–affinity relationship Fulltext Access 11 Pages 2007
Eudragit RS 100 microparticles containing 2-hydroxypropyl-β-cyclodextrin and glutathione: Physicochemical characterization, drug release and transport studies Fulltext Access 11 Pages 2007
Population pharmacokinetic model of fluvoxamine in rats: Utility for application in animal behavioral studies Fulltext Access 11 Pages 2007
Permeation of permanently positive charged molecules through artificial membranes—Influence of physico-chemical properties Fulltext Access 11 Pages 2007
A simulation study with statistical evaluation for the determination of non-isothermal kinetics conditions in drugs stability Fulltext Access 11 Pages 2007
Inhalable microparticles containing large payload of anti-tuberculosis drugs Fulltext Access 11 Pages 2007
In vitro and in vivo evaluation of a fast-disintegrating lyophilized dry emulsion tablet containing griseofulvin Fulltext Access 11 Pages 2007
Mechanistic study on the intestinal absorption and disposition of baicalein Fulltext Access 11 Pages 2007
Quantifying ternary mixtures of different solid-state forms of indomethacin by Raman and near-infrared spectroscopy Fulltext Access 11 Pages 2007
Difunctional Pluronic copolymer micelles for paclitaxel delivery: Synergistic effect of folate-mediated targeting and Pluronic-mediated overcoming multidrug resistance in tumor cell lines Fulltext Access 11 Pages 2007
Use of surfactants as plasticizers in preparing solid dispersions of poorly soluble API: Selection of polymer–surfactant combinations using solubility parameters and testing the processability Fulltext Access 11 Pages 2007
Xanthan–alginate composite gel beads: Molecular interaction and in vitro characterization Fulltext Access 11 Pages 2007
Stabilization of protein encapsulated in poly(lactide-co-glycolide) microspheres by novel viscous S/W/O/W method Fulltext Access 11 Pages 2007
Humidity-induced changes of the aerodynamic properties of dry powder aerosol formulations containing different carriers Fulltext Access 11 Pages 2007
Alginate-magnesium aluminum silicate films: Effect of plasticizers on film properties, drug permeation and drug release from coated tablets Fulltext Access 11 Pages 2007
Investigation of surface-modified solid lipid nanocontainers formulated with a heterolipid-templated homolipid Fulltext Access 11 Pages 2007
Experimental study of wet granulation in fluidized bed: Impact of the binder properties on the granule morphology Fulltext Access 11 Pages 2007
Novel hybrid silica xerogels for stabilization and controlled release of drug Fulltext Access 11 Pages 2007
Influence of the formulation on the tolerance profile of nanoparticle-bound doxorubicin in healthy rats: Focus on cardio- and testicular toxicity Fulltext Access 11 Pages 2007
Induction of lymphocytes activated marker CD69 following exposure to chitosan and alginate biopolymers Fulltext Access 11 Pages 2007
Structure–activity relationship analysis of a novel necroptosis inhibitor, Necrostatin-5 Fulltext Access 11 Pages 2007
Comparison of cytochrome P450 inhibition assays for drug discovery using human liver microsomes with LC–MS, rhCYP450 isozymes with fluorescence, and double cocktail with LC–MS Fulltext Access 11 Pages 2007
Effect of preparation method on compactability of paracetamol granules and agglomerates Fulltext Access 11 Pages 2007
Solid dispersions of itraconazole and enteric polymers made by ultra-rapid freezing Fulltext Access 11 Pages 2007
Parallel screening approach to identify solubility-enhancing formulations for improved bioavailability of a poorly water-soluble compound using milligram quantities of material Fulltext Access 11 Pages 2007
5-Fluorouracil plasma levels and biodegradation of subcutaneously injected drug-loaded microspheres prepared by spray-drying poly(d,l-lactide) and poly(d,l-lactide-co-glycolide) polymers Fulltext Access 11 Pages 2007
The effect of water solubility of solutes on their flux through human skin in vitro: An extended Flynn database fitted to the Roberts–Sloan equation Fulltext Access 11 Pages 2007
Combined effects of iontophoretic and chemical enhancement on drug delivery Fulltext Access 11 Pages 2007
Process analytical technology (PAT): Effects of instrumental and compositional variables on terahertz spectral data quality to characterize pharmaceutical materials and tablets Fulltext Access 11 Pages 2007
Novel isomarabarican triterpenes, exhibiting selective anti-proliferative activity against vascular endothelial cells, from marine sponge Rhabdastrella globostellata Fulltext Access 11 Pages 2007
The 1,4-naphthoquinone scaffold in the design of cysteine protease inhibitors Fulltext Access 11 Pages 2007
Synthesis and HCV inhibitory properties of 9-deaza- and 7,9-dideaza-7-oxa-2′-C-methyladenosine Fulltext Access 11 Pages 2007
Pyrrolidinones as orally bioavailable antagonists of the human melanocortin-4 receptor with anti-cachectic activity Fulltext Access 11 Pages 2007
Design, synthesis, binding, and molecular modeling studies of new potent ligands of cannabinoid receptors Fulltext Access 11 Pages 2007
Second generation of α-tocopherol analogs-nitric oxide donors: Synthesis, physicochemical, and biological characterization Fulltext Access 11 Pages 2007
2D Quantitative structure–activity relationship studies on a series of cholesteryl ester transfer protein inhibitors Fulltext Access 11 Pages 2007
Estimation of hERG inhibition of drug candidates using multivariate property and pharmacophore SAR Fulltext Access 11 Pages 2007
α-Substituted N-(4-tert-butylbenzyl)-N′-[4-(methylsulfonylamino)benzyl]thiourea analogues as potent and stereospecific TRPV1 antagonists Fulltext Access 11 Pages 2007
Optimization and determination of the absolute configuration of a series of potent inhibitors of human papillomavirus type-11 E1–E2 protein–protein interaction: A combined medicinal chemistry, NMR and computational chemistry approach Fulltext Access 11 Pages 2007
Novel chiral isoxazole derivatives: Synthesis and pharmacological characterization at human β-adrenergic receptor subtypes Fulltext Access 11 Pages 2007
Development of Tyrocidine A analogues with improved antibacterial activity Fulltext Access 11 Pages 2007
Comparative molecular field analysis of flavonoid inhibitors of the PIM-1 kinase Fulltext Access 11 Pages 2007
Construction of a three-dimensional pharmacophore for Bcl-2 inhibitors by flexible docking and the multiple copy simultaneous search method Fulltext Access 11 Pages 2007
Determination of neomycin sulfate and impurities using high-performance anion-exchange chromatography with integrated pulsed amperometric detection Fulltext Access 11 Pages 2007
Fingerprint analysis of the fruits of Cnidium monnieri extract by high-performance liquid chromatography–diode array detection–electrospray ionization tandem mass spectrometry Fulltext Access 11 Pages 2007
Impurity profiling of atropine sulfate by microemulsion electrokinetic chromatography Fulltext Access 11 Pages 2007
Development and validation of a quantitative cell-based bioassay for comparing the pharmacokinetic profiles of two recombinant erythropoietic proteins in serum Fulltext Access 11 Pages 2007
Evaluation of monolithic HPLC columns for various pharmaceutical separations: Method transfer from conventional phases and batch to batch repeatability Fulltext Access 11 Pages 2007
Chromatographic analysis and decomposition product characterization of compound SR16157 (NSC 732011) Fulltext Access 11 Pages 2007
Metabolism of a 14C/3H-labeled GABAA receptor partial agonist in rat, dog and human liver microsomes: Evaluation of a dual-radiolabel strategy Fulltext Access 11 Pages 2007
Identification of tanshinones and their metabolites in rat bile after oral administration of TTE-50, a standardized extract of Salvia miltiorrhiza by HPLC–ESI–DAD–MSn Fulltext Access 11 Pages 2007
Recent applications of liquid chromatography–mass spectrometry in natural products bioanalysis Fulltext Access 11 Pages 2007
Identification of a series of novel derivatives as potent HCV inhibitors by a ligand-based virtual screening optimized procedure Fulltext Access 11 Pages 2007
Ring substituent effects on biological activity of vinyl sulfones as inhibitors of HIV-1 Fulltext Access 11 Pages 2007
4-Pyridone derivatives as new inhibitors of bacterial enoyl-ACP reductase FabI Fulltext Access 11 Pages 2007
Influence of the position of substituents in the cytotoxic activity of trans platinum complexes with hydroxymethyl pyridines Fulltext Access 11 Pages 2007
Design and study of some novel ibuprofen derivatives with potential nootropic and neuroprotective properties Fulltext Access 11 Pages 2007
Dioxane and oxathiane nuclei: Suitable substructures for muscarinic agonists Fulltext Access 11 Pages 2007
Chemoenzymatic synthesis of artificial glycopolypeptides containing multivalent sialyloligosaccharides with a γ-polyglutamic acid backbone and their effect on inhibition of infection by influenza viruses Fulltext Access 11 Pages 2007
Mimetics of the tri- and tetrasaccharide epitope of GQ1bα as myelin-associated glycoprotein (MAG) ligands Fulltext Access 11 Pages 2007
Synthesis and biological evaluation of non-peptide αvβ3/α5β1 integrin dual antagonists containing 5,6-dihydropyridin-2-one scaffolds Fulltext Access 11 Pages 2007
Additional level of information about complex interaction between non-nucleoside inhibitor and HIV-1 reverse transcriptase using biosensor-based thermodynamic analysis Fulltext Access 11 Pages 2007
The use of mixed-mode ion-exchange solid phase extraction to characterize pharmaceutical drug degradation Fulltext Access 11 Pages 2007
Novel synthesis of [1]-benzothiepino[5,4-b]pyridine-3-carbonitriles and their anti-inflammatory properties Fulltext Access 11 Pages 2007
Novel piperazines: Potent melanocortin-4 receptor antagonists with anxiolytic-like activity Fulltext Access 11 Pages 2007
Cholinesterase inhibitors: SAR and enzyme inhibitory activity of 3-[ω-(benzylmethylamino)alkoxy]xanthen-9-ones Fulltext Access 11 Pages 2007
Modifications of the pyroglutamic acid and histidine residues in thyrotropin-releasing hormone (TRH) yield analogs with selectivity for TRH receptor type 2 over type 1 Fulltext Access 11 Pages 2007
Synthesis and SAR study of novel 7-(pyridinium-3-yl)-carbonyl imidazo[5,1-b]thiazol-2-yl carbapenems Fulltext Access 11 Pages 2007
Chemoselective synthesis of erythromycin A ketolides substituted in the C10-methyl group Fulltext Access 11 Pages 2007
Synthesis, biological evaluation and molecular modelling of sulfonohydrazides as selective PI3K p110α inhibitors Fulltext Access 11 Pages 2007
In vitro affinities of various halogenated benzamide derivatives as potential radioligands for non-invasive quantification of D2-like dopamine receptors Fulltext Access 11 Pages 2007
Synthesis and evaluation of antifungal properties of a series of the novel 2-amino-5-oxo-4-phenyl-5,6,7,8-tetrahydroquinoline-3-carbonitrile and its analogues Fulltext Access 11 Pages 2007