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Daneshyari Pharmaceutical Science Journas Latest Articles

Pharmaceutical Science Research Articles

Photosensitiser-loaded biodegradable polymeric micelles: Preparation, characterisation and in vitro PDT efficacy
Fulltext Access 10 Pages 2007
β-Lapachone-containing PEG–PLA polymer micelles as novel nanotherapeutics against NQO1-overexpressing tumor cells
Fulltext Access 10 Pages 2007
Effect of polymer molecular weight on the tumor targeting characteristics of self-assembled glycol chitosan nanoparticles
Fulltext Access 10 Pages 2007
Production of heparin-functionalized hydrogels for the development of responsive and controlled growth factor delivery systems
Fulltext Access 10 Pages 2007
Electrophoretic purification of tumor-targeted polyethylenimine-based polyplexes reduces toxic side effects in vivo
Fulltext Access 10 Pages 2007
Wanted and unwanted properties of surface PEGylated nucleic acid nanoparticles in ocular gene transfer
Fulltext Access 10 Pages 2007
Inhibition of transferrin iron release increases in vitro drug carrier efficacy
Fulltext Access 10 Pages 2007
Poly(ethylene carbonate): A thermoelastic and biodegradable biomaterial for drug eluting stent coatings?
Fulltext Access 10 Pages 2007
Comparison of the endocytic properties of linear and branched PEIs, and cationic PAMAM dendrimers in B16f10 melanoma cells
Fulltext Access 10 Pages 2007
Factors modulating the delivery and effect of enzymatic cargo conjugated with antibodies targeted to the pulmonary endothelium
Fulltext Access 10 Pages 2007
Evaluation of bioadhesive polymers as delivery systems for nose to brain delivery: In vitro characterisation studies
Fulltext Access 10 Pages 2007
Glucosylated heparin derivatives as non-toxic anti-cancer drugs
Fulltext Access 10 Pages 2007
Cationic lipids and polymers mediated vectors for delivery of siRNA
Fulltext Access 10 Pages 2007
Piezoelectric control of needle-free transdermal drug delivery
Fulltext Access 10 Pages 2007
Transport mechanisms of mmePEG750P(CL-co-TMC) polymeric micelles across the intestinal barrier
Fulltext Access 10 Pages 2007
PLGA nanoparticles for oral delivery of cyclosporine: Nephrotoxicity and pharmacokinetic studies in comparison to Sandimmune Neoral®
Fulltext Access 10 Pages 2007
Towards controlled release of BDNF — Manufacturing strategies for protein-loaded lipid implants and biocompatibility evaluation in the brain
Fulltext Access 10 Pages 2007
10-Hydroxycamptothecin loaded nanoparticles: Preparation and antitumor activity in mice
Fulltext Access 10 Pages 2007
Delivery of G3139 using releasable PEG-linkers: Impact on pharmacokinetic profile and anti-tumor efficacy
Fulltext Access 10 Pages 2007
On the design of in situ forming biodegradable parenteral depot systems based on insulin loaded dialkylaminoalkyl-amine-poly(vinyl alcohol)-g-poly(lactide-co-glycolide) nanoparticles
Fulltext Access 10 Pages 2007
Expression profile of plasmid DNA by spermine derivatives of pullulan with different extents of spermine introduced
Fulltext Access 10 Pages 2007
Acoustically-active microbubbles conjugated to liposomes: Characterization of a proposed drug delivery vehicle
Fulltext Access 10 Pages 2007
Gastrointestinal distribution and in vivo gene transfection studies with nanoparticles-in-microsphere oral system (NiMOS)
Fulltext Access 10 Pages 2007
Synthesis, biodistribution and excretion of radiolabeled poly(2-alkyl-2-oxazoline)s
Fulltext Access 10 Pages 2007
Design, parallel synthesis and SAR of novel urotensin II receptor agonists
Fulltext Access 10 Pages 2007
Highly efficient and carcinoma-specific adenoviral replication restricted by the EGP-2 promoter
Fulltext Access 10 Pages 2007
A mechanistic model of controlled drug release from polymer millirods: Effects of excipients and complex binding
Fulltext Access 10 Pages 2007
Development and evaluation of novel biodegradable microspheres based on poly(d,l-lactide-co-glycolide) and poly(ε-caprolactone) for controlled delivery of doxycycline in the treatment of human periodontal pocket: In vitro and in vivo studies
Fulltext Access 10 Pages 2007
New packaging method of mycobacterial cell wall using octaarginine-modified liposomes: Enhanced uptake by and immunostimulatory activity of dendritic cells
Fulltext Access 10 Pages 2007
Bio-distribution, toxicity and pathology of cowpea mosaic virus nanoparticles in vivo
Fulltext Access 10 Pages 2007
Post-pegylated lipoplexes are promising vehicles for gene delivery in RPE cells
Fulltext Access 10 Pages 2007
Nanolayer biomaterial coatings of silk fibroin for controlled release
Fulltext Access 10 Pages 2007
Optimization of (1,2-diamino-cyclohexane)platinum(II)-loaded polymeric micelles directed to improved tumor targeting and enhanced antitumor activity
Fulltext Access 10 Pages 2007
Synergistic effect of ultrasound and PEI on DNA transfection in vitro
Fulltext Access 10 Pages 2007
Optimising histidine rich peptides for efficient DNA delivery in the presence of serum
Fulltext Access 10 Pages 2007
Synthesis and characterization of guanidinylated poly(propylene imine) dendrimers as gene transfection agents
Fulltext Access 10 Pages 2007
Coating of negatively charged liposomes by polylysine: Drug release study
Fulltext Access 10 Pages 2007
Sustained release of bioactive therapeutic proteins from a biodegradable elastomeric device
Fulltext Access 10 Pages 2007
3D-QSAR and molecular docking studies on benzothiazole derivatives as Candida albicans N-myristoyltransferase inhibitors
Fulltext Access 10 Pages 2007
Effective uptake of N-acetylglucosamine-conjugated liposomes by cardiomyocytes in vitro
Fulltext Access 10 Pages 2007
Effective oral delivery of insulin in animal models using vitamin B12-coated dextran nanoparticles
Fulltext Access 10 Pages 2007
PEGylated PLGA-based nanoparticles targeting M cells for oral vaccination
Fulltext Access 10 Pages 2007
NanoCipro encapsulation in monodisperse large porous PLGA microparticles
Fulltext Access 10 Pages 2007
Periodontal regeneration using novel glycidyl methacrylated dextran (Dex-GMA)/gelatin scaffolds containing microspheres loaded with bone morphogenetic proteins
Fulltext Access 10 Pages 2007
Polymer-based siRNA delivery: Perspectives on the fundamental and phenomenological distinctions from polymer-based DNA delivery
Fulltext Access 10 Pages 2007
Colloidally stable novel copolymeric system for gene delivery in complete growth media
Fulltext Access 10 Pages 2007
Mechanisms of co-modified liver-targeting liposomes as gene delivery carriers based on cellular uptake and antigens inhibition effect
Fulltext Access 10 Pages 2007
Bubble growth within the skin by rectified diffusion might play a significant role in sonophoresis
Fulltext Access 10 Pages 2007
Delivery of photosensitisers and light through mucus: Investigations into the potential use of photodynamic therapy for treatment of Pseudomonas aeruginosa cystic fibrosis pulmonary infection
Fulltext Access 10 Pages 2007
Enzymosomes with surface-exposed superoxide dismutase: In vivo behaviour and therapeutic activity in a model of adjuvant arthritis
Fulltext Access 10 Pages 2007
Study of ascorbic acid interaction with hydroxypropyl-β-cyclodextrin and triethanolamine, separately and in combination
Fulltext Access 10 Pages 2007
Structural analysis of photo-degradation in thiazole-containing compounds by LC–MS/MS and NMR
Fulltext Access 10 Pages 2007
Immobilized P2X2 purinergic receptor stationary phase for chromatographic determination of pharmacological properties and drug screening
Fulltext Access 10 Pages 2007
Identification of imatinib mesylate degradation products obtained under stress conditions
Fulltext Access 10 Pages 2007
Sample preparation strategy for the simultaneous determination of macrolide antibiotics in animal feedingstuffs by liquid chromatography with electrochemical detection (HPLC-ECD)
Fulltext Access 10 Pages 2007
A novel antibiotic bone assay by liquid chromatography/tandem mass spectrometry for quantitation of tigecycline in rat bone
Fulltext Access 10 Pages 2007
Pharmaceutical analysis of synthetic lipid A-based vaccine adjuvants in poly (d,l-lactic-co-glycolic acid) nanoparticle formulations
Fulltext Access 10 Pages 2007
Determination of neomycin and bacitracin in human or rabbit serum by HPLC–MS/MS
Fulltext Access 10 Pages 2007
Effect of system variables involved in packed column supercritical fluid chromatography of stavudine taken as model analyte using response surface methodology along with study of thermodynamic parameters
Fulltext Access 10 Pages 2007
Quantification of nitrated tryptophan in proteins and tissues by high-performance liquid chromatography with electrospray ionization tandem mass spectrometry
Fulltext Access 10 Pages 2007
Applying spectral peak area analysis in near-infrared spectroscopy moisture assays
Fulltext Access 10 Pages 2007
Analysis of underivatized polyamines by reversed phase liquid chromatography with electrospray tandem mass spectrometry
Fulltext Access 10 Pages 2007
Comparison of solid-phase microextraction and liquid–liquid extraction in 96-well format for the determination of a drug compound in human plasma by liquid chromatography with tandem mass spectrometric detection
Fulltext Access 10 Pages 2007
Development and application of electrospray-active derivatization reagents for hydroxysteroids
Fulltext Access 10 Pages 2007
Simultaneous determination of safflor yellow A, puerarin, daidzein, ginsenosides (Rg1, Rb1, Rd), and notoginsenoside R1 in rat plasma by liquid chromatography–mass spectrometry
Fulltext Access 10 Pages 2007
Response surface analysis of solution-mediated polymorphic transformation of buspirone hydrochloride
Fulltext Access 10 Pages 2007
Structural identification and characterization of potential impurities of pantoprazole sodium1
Fulltext Access 10 Pages 2007
Liquid chromatography tandem mass spectrometry method for simultaneous determination of antidiabetic drugs metformin and glyburide in human plasma
Fulltext Access 10 Pages 2007
Isolation and identification of impurities in chlorin e6
Fulltext Access 10 Pages 2007
Improved quality control method for Fufang Danshen preparations through simultaneous determination of phenolic acids, saponins and diterpenoid quinones by HPLC coupled with diode array and evaporative light scattering detectors
Fulltext Access 10 Pages 2007
Exploration of liquid and supercritical fluid chromatographic chiral separation and purification of Nutlin-3—A small molecule antagonist of MDM2
Fulltext Access 10 Pages 2007
Isolation, identification and determination of the major degradation product in alprazolam tablets during their stability assay
Fulltext Access 10 Pages 2007
On-line H/D exchange LC–MS strategy for structural elucidation of pharmaceutical impurities
Fulltext Access 10 Pages 2007
Characterization of flavonoids in the extract of Sophora flavescens Ait. by high-performance liquid chromatography coupled with diode-array detector and electrospray ionization mass spectrometry
Fulltext Access 10 Pages 2007
Validated stability-indicating methods for determination of cilostazol in the presence of its degradation products according to the ICH guidelines
Fulltext Access 10 Pages 2007
Development of integrase inhibitors for treatment of AIDS: An overview
Fulltext Access 10 Pages 2007
Design, synthesis and cytotoxic properties of novel 1-[4-(2-alkylaminoethoxy)phenylcarbonyl]-3,5-bis(arylidene)-4-piperidones and related compounds
Fulltext Access 10 Pages 2007
Design, synthesis, biochemical evaluation and antimycobacterial action of phosphonate inhibitors of antigen 85C, a crucial enzyme involved in biosynthesis of the mycobacterial cell wall
Fulltext Access 10 Pages 2007
Synthesis and in vitro antitumor effect of diclofenac and fenoprofen thiolated and nonthiolated polyaspartamide-drug conjugates
Fulltext Access 10 Pages 2007
Docking and quantum mechanic studies on cholinesterases and their inhibitors
Fulltext Access 10 Pages 2007
Effect of substituents on diarylmethanes for antitubercular activity
Fulltext Access 10 Pages 2007
Identification of novel short chain 4-substituted indoles as potent αvβ3 antagonist using structure-based drug design
Fulltext Access 10 Pages 2007
Synthesis, stereochemistry and antimicrobial evaluation of some N-morpholinoacetyl-2,6-diarylpiperidin-4-ones
Fulltext Access 10 Pages 2007
Quinone reductase induction activity of methoxylated analogues of resveratrol
Fulltext Access 10 Pages 2007
Clubbed triazoles: A novel approach to antitubercular drugs
Fulltext Access 10 Pages 2007
Synthesis and pharmacological evaluation of novel conformationally constrained homologues of glutamic acid
Fulltext Access 10 Pages 2007
Syntheses of new tetrasubstituted thiophenes as novel anti-inflammatory agents
Fulltext Access 10 Pages 2007
Synthesis of some new bioactive 3-amino-2-mercapto-5,6,7,8-tetrahydro[1]benzothieno[2,3-d]pyrimidin-4(3H)-one derivatives
Fulltext Access 10 Pages 2007
Analysis of the polyphenolic fraction of propolis from different sources by liquid chromatography–tandem mass spectrometry
Fulltext Access 10 Pages 2007
Synthesis, antibacterial activity, and quantitative structure–activity relationships of new (Z  )-2-(nitroimidazolylmethylene)-3(2H2H)-benzofuranone derivatives
Fulltext Access 10 Pages 2007
2-Styrylchromones: Novel strong scavengers of reactive oxygen and nitrogen species
Fulltext Access 10 Pages 2007
Design, synthesis, inhibitory activity, and SAR studies of pyrrolidine derivatives as neuraminidase inhibitors
Fulltext Access 10 Pages 2007
QSAR analysis for heterocyclic antifungals
Fulltext Access 10 Pages 2007
Clubbed thiazoles by MAOS: A novel approach to cyclin-dependent kinase 5/p25 inhibitors as a potential treatment for Alzheimer’s disease
Fulltext Access 10 Pages 2007
Inhibition of colon cancer cell growth and antioxidant activity of bioactive compounds from Poncirus trifoliata (L.) Raf.
Fulltext Access 10 Pages 2007
A novel approach to cyclin-dependent kinase 5/p25 inhibitors: A potential treatment for Alzheimer’s disease
Fulltext Access 10 Pages 2007
Development and validation of chemometrics-assisted spectrophotometric and liquid chromatographic methods for the simultaneous determination of two multicomponent mixtures containing bronchodilator drugs
Fulltext Access 10 Pages 2007
Evaluation of the iCE280 Analyzer as a potential high-throughput tool for formulation development
Fulltext Access 10 Pages 2007
Study of the physicochemical properties in aqueous medium and molecular modeling of tagitinin C/cyclodextrin complexes
Fulltext Access 10 Pages 2007
Evaluation of an International Pharmacopoeia method for the analysis of saquinavir (mesilate) bulk drugs by liquid chromatography
Fulltext Access 10 Pages 2007
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