Remission induction by Raising the dose of Remicade in RA (RRRR) study: Rationale and study protocol for a randomized controlled trial comparing for sustained clinical remission after discontinuation of infliximab in patients with rheumatoid arthritis Fulltext Access 6 Pages 2017
Skeletal muscle autophagy and its role in sarcopenia and organismal aging Fulltext Access 6 Pages 2017
In vivo infection models in the pre-clinical pharmacokinetic/pharmacodynamic evaluation of antimicrobial agents Fulltext Access 6 Pages 2017
Tocilizumab Promotes Regulatory T-cell Alleviation in STAT3 Gain-of-functionâassociated Multi-organ Autoimmune Syndrome Fulltext Access 6 Pages 2017
Phytochemical composition and antibacterial activity of the essential oils from different parts of sea buckthorn (Hippophae rhamnoides L.) Fulltext Access 6 Pages 2017
Determination of urea in milk based on N-bromosuccinimide-dichlorofluorescein postchemiluminescence method Fulltext Access 6 Pages 2017
The over-representation of significant p values in abstracts compared to corresponding full texts: A systematic review of surgical randomized trials Fulltext Access 6 Pages 2017
Assessing the feasibility, acceptability, and potential effectiveness of a behavioral-automaticity focused lifestyle intervention for African Americans with metabolic syndrome: The Pick two to Stick to protocol Fulltext Access 6 Pages 2017
Mediterranean diet based intervention in pregnancy to improve maternal and fetal outcomes: Methodological challenges and lessons learned from the multicentre ESTEEM study Fulltext Access 6 Pages 2017
ASSERT trial - How to assess the safety and efficacy of a high frequency rTMS in postpartum depression ? A multicenter, double blinded, randomized, placebo-controlled clinical trial Fulltext Access 6 Pages 2017
Rationale and design of DUAL study: Doxycycline to Upgrade response in light chain (AL) amyloidosis (DUAL): A phase 2 pilot study of a two-pronged approach of prolonged doxycycline with plasma cell-directed therapy in the treatment of AL amyloidosis Fulltext Access 6 Pages 2017
Proanthocyanidins from Vitis vinifera inhibit oxidative stress-induced vascular impairment in pulmonary arteries from diabetic rats Fulltext Access 6 Pages 2017
Antitrypanosomal activity and evaluation of the mechanism of action of dehydrodieugenol isolated from Nectandra leucantha (Lauraceae) and its methylated derivative against Trypanosoma cruzi Fulltext Access 6 Pages 2017
Ephenidine: A new psychoactive agent with ketamine-like NMDA receptor antagonist properties Fulltext Access 6 Pages 2017
A slow excitatory postsynaptic current mediated by a novel metabotropic glutamate receptor in CA1 pyramidal neurons Fulltext Access 6 Pages 2017
C0818, a novel curcumin derivative, interacts with Hsp90 and inhibits Hsp90 ATPase activity Fulltext Access 6 Pages 2017
Euphorbia factor L2 induces apoptosis in A549 cells through the mitochondrial pathway Fulltext Access 6 Pages 2017
Aromatic compounds from an aqueous extract of “ban lan gen” and their antiviral activities Fulltext Access 6 Pages 2017
ORIGINAL ARTICLEA set of interesting sequoiatones stereoisomers from a wetland soil-derived fungus Talaromyces flavus Fulltext Access 6 Pages 2017
Sex and gender differences in the treatment of Alzheimer's disease: A systematic review of randomized controlled trials Fulltext Access 6 Pages 2017
Use of Bayesian Methods to Analyze and Visualize Content Uniformity Capability Versus United States Pharmacopeia and ASTM Standards Fulltext Access 6 Pages 2017
Simultaneous estimation of Ofloxacin and Cefixime in tablet form in presence of the inactive Ofloxacin USP Related compound A Fulltext Access 6 Pages 2017
Quercetin nanoparticles attenuates scopolamine induced spatial memory deficits and pathological damages in rats Fulltext Access 6 Pages 2017
A validated HPTLC method for the quantification of friedelin in Putranjiva roxburghii Wall extracts and in polyherbal formulations Fulltext Access 6 Pages 2017
TLC-densitometric and first derivative spectrophotometric methods for determination of cefoxitin-sodium in presence of its alkali-induced degradation product Fulltext Access 6 Pages 2017
Ãvolution des stratégies thérapeutiques et du parcours de soins du patient diabétique Fulltext Access 6 Pages 2017
Overview of 3Rs opportunities in drug discovery and development using non-human primates Fulltext Access 6 Pages 2017
Isocitrate dehydrogenase (IDH) inhibition as treatment of myeloid malignancies: Progress and future directions Fulltext Access 6 Pages 2017
Scanometry as microplate reader for high throughput method based on DPPH dry reagent for antioxidant assay Fulltext Access 6 Pages 2017
Adrenoceptors promote glucose uptake into adipocytes and muscle by an insulin-independent signaling pathway involving mechanistic target of rapamycin complex 2 Fulltext Access 6 Pages 2017
Polypharmacy in older adults: Association Rule and Frequent-Set Analysis to evaluate concomitant medication use Fulltext Access 6 Pages 2017
Cannabidiol in medical marijuana: Research vistas and potential opportunities Fulltext Access 6 Pages 2017
Anti-CD3 antibody therapy attenuates the progression of hypertension in female mice with systemic lupus erythematosus Fulltext Access 6 Pages 2017
Lignocaine augments the in-vitro uterine contractions involving NO-guanylyl cyclase dependent mechanisms Fulltext Access 6 Pages 2017
In vitro metabolism of 4, 5-dimethoxycanthin-6-one by human liver microsomes and its inhibition on human CYP1A2 Fulltext Access 6 Pages 2017
Expression of AR, 5αR1 and 5αR2 in bladder urothelial carcinoma and relationship to clinicopathological factors Fulltext Access 6 Pages 2017
Maternal ethanol consumption reduces Se antioxidant function in placenta and liver of embryos and breastfeeding pups Fulltext Access 6 Pages 2017
Effects of N-acetylcysteine on isolated skeletal muscle contractile properties after an acute bout of aerobic exercise Fulltext Access 6 Pages 2017
Original articleThe NK-1 receptor antagonist L-732,138 induces apoptosis in human gastrointestinal cancer cell lines Fulltext Access 6 Pages 2017
Research articleNicotine pretreatment reduced cocaine-induced CPP and its reinstatement in a sex- and dose-related manner in adult C57BL/6J mice Fulltext Access 6 Pages 2017
Ceftriaxone reduces alcohol intake in outbred rats while upregulating xCT in the nucleus accumbens core Fulltext Access 6 Pages 2017
Research articleIncubation of cue-induced reinstatement of cocaine, but not sucrose, seeking in C57BL/6J mice Fulltext Access 6 Pages 2017
Research articleÎ9-tetrahydrocannabinol (Î9-THC) administration after neonatal exposure to phencyclidine potentiates schizophrenia-related behavioral phenotypes in mice Fulltext Access 6 Pages 2017
Research articleThe new HDAC1 inhibitor LG325 ameliorates neuropathic pain in a mouse model Fulltext Access 6 Pages 2017
Effects of the dimeric PSD-95 inhibitor UCCB01-144 on functional recovery after fimbria-fornix transection in rats Fulltext Access 6 Pages 2017
Original articleFear memory in a neurodevelopmental model of schizophrenia based on the postnatal blockade of NMDA receptors Fulltext Access 6 Pages 2017
Differential effects of liver steatosis on pharmacokinetic profile of two closely related hepatoselective NO-donors; V-PYRRO/NO and V-PROLI/NO Fulltext Access 6 Pages 2017
Original articleThe effects of desipramine, fluoxetine, or tianeptine on changes in bulbar BDNF levels induced by chronic social instability stress and inflammation Fulltext Access 6 Pages 2017
Original articlePharmacological effects of β-d-mannuronic acid (M2000) on miR-146a, IRAK1, TRAF6 and NF-κB gene expression, as target molecules in inflammatory reactions Fulltext Access 6 Pages 2017
Original articleC-phycocyanin suppresses transforming growth factor-β1-induced epithelial mesenchymal transition in human epithelial cells Fulltext Access 6 Pages 2017
Original articleEtidronate down-regulates Toll-like receptor (TLR) 2 ligand-induced proinflammatory cytokine production by inhibiting NF-κB activation Fulltext Access 6 Pages 2017
P2 purinergic receptor antagonists disrupt maternal behavior in lactating rats Fulltext Access 6 Pages 2017
Original articleMagnolol attenuates the inflammation and apoptosis through the activation of SIRT1 in experimental stroke rats Fulltext Access 6 Pages 2017
Original articleThe role of arachidonic acid/cyclooxygenase cascade, phosphodiesterase IV and Rho-kinase in H2S-induced relaxation in the mouse corpus cavernosum Fulltext Access 6 Pages 2017
Original articleEnhancement of oral bioavailability of rivastigmine with quercetin nanoparticles by inhibiting CYP3A4 and esterases Fulltext Access 6 Pages 2017
Original articleOn the sulfation of O-desmethyltramadol by human cytosolic sulfotransferases Fulltext Access 6 Pages 2017
Effects of atrazine on ovarian growth, in the estuarine crab Neohelice granulata Fulltext Access 6 Pages 2017
Electrophysiological activity of a neurotoxic fraction from the venom of box jellyfish Carybdea marsupialis Fulltext Access 6 Pages 2017
Growth, blood health, antioxidant status, immune response and resistance to Aeromonas hydrophila of juvenile yellow catfish exposed to di-2-ethylhexyl phthalate (DEHP) Fulltext Access 6 Pages 2017
L'analgésie acupuncturale : une pratique controversée. « Qu'est ce qui sous-tend l'analgésie induite par acupuncture, sham ou réelle ? » Fulltext Access 6 Pages 2017
L'évaluation psychiatrique pour la pose d'un neurostimulateur médullaire Fulltext Access 6 Pages 2017
Le syndrome de Pancoast-Tobias : une entité à plusieurs visages, à propos de 95 cas Fulltext Access 6 Pages 2017
PerspectiveFeatureUpdating molecular properties during early drug discovery Fulltext Access 6 Pages 2017
Arylamine N-acetyltransferase 2 genotype-dependent N-acetylation of isoniazid in cryopreserved human hepatocytes Fulltext Access 6 Pages 2017
Crystal structures, absolute configurations and molecular docking studies of naftopidil enantiomers as α1D-adrenoceptor antagonists Fulltext Access 6 Pages 2017
Phytochemical study of Illicium angustisepalum and its biological activities Fulltext Access 6 Pages 2017
3,5-Bis(arylidene)-4-piperidones as potential dengue protease inhibitors Fulltext Access 6 Pages 2017
Diagnostic accuracy of CSF neurofilament light chain protein in the biomarker-guided classification system for Alzheimer's disease Fulltext Access 6 Pages 2017
Blockade of intracellular Zn2+ signaling in the basolateral amygdala affects object recognition memory via attenuation of dentate gyrus LTP Fulltext Access 6 Pages 2017
Rapid communicationLow serum vitamin D levels and anti-N-methyl-d-aspartate receptor encephalitis: A case-control study Fulltext Access 6 Pages 2017
Homovanillic acid in CSF of mild stage Parkinson's disease patients correlates with motor impairment Fulltext Access 6 Pages 2017
Does acupuncture ameliorate motor impairment after stroke? An assessment using the CatWalk gait system Fulltext Access 6 Pages 2017
Review InformaticsNext-generation sequencing: big data meets high performance computing Fulltext Access 6 Pages 2017
PerspectiveFeatureRejecting the Alzheimer's disease vaccine development for the wrong reasons Fulltext Access 6 Pages 2017
PerspectiveFeatureMinimizing the risk of chemically reactive metabolite formation of new drug candidates: implications for preclinical drug design Fulltext Access 6 Pages 2017
ReviewPost screenBioimaging of nanoparticles: the crucial role of discriminating nanoparticles from free probes Fulltext Access 6 Pages 2017
PerspectiveFeatureSemiconductor technology in protein kinase research and drug discovery: sensing a revolution Fulltext Access 6 Pages 2017
PerspectiveFeatureThe implications of model-informed drug discovery and development for tuberculosis Fulltext Access 6 Pages 2017
ReviewPost screenRecombinant high-density lipoproteins and their use in cardiovascular diseases Fulltext Access 6 Pages 2017
ReviewPost-screenPredicting toxicities in humans by nonclinical safety testing: an update with particular reference to anticancer compounds Fulltext Access 6 Pages 2017
FeatureThorough QT (TQT) studies: concordance with torsadogenesis and an evolving cardiac safety testing paradigm Fulltext Access 6 Pages 2017
Further evaluation of the potential anxiolytic activity of imidazo[1,5-a][1,4]diazepin agents selective for α2/3-containing GABAA receptors Fulltext Access 6 Pages 2017
Involvement of presynaptic 5-HT1A receptors in the low propensity of brexpiprazole to induce extrapyramidal side effects in rats Fulltext Access 6 Pages 2017
Stress-induced change in serum BDNF is related to quantitative family history of alcohol use disorder and age at first alcohol use Fulltext Access 6 Pages 2017