Directions in QPPR development to complement the predictive models used in risk assessment of nanomaterials Fulltext Access 29 Pages 2018
CpG-oligodeoxynucleotides may be effective for preventing ionizing radiation induced pulmonary fibrosis Fulltext Access 29 Pages 2018
Mice deficient in aldo-keto reductase 1a (Akr1a) are resistant to thioacetamide-induced liver injury Fulltext Access 29 Pages 2018
Exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin promotes inflammation in mouse testes: The critical role of Klotho in Sertoli cells Fulltext Access 29 Pages 2018
Decreased H3K9ac level of StAR mediated testicular dysplasia induced by prenatal dexamethasone exposure in male offspring rats Fulltext Access 29 Pages 2018
2,3,7,8-Tetrachlorodibenzo-p-dioxin can alter the sex ratio of embryos with decreased viability of Y spermatozoa in mice Fulltext Access 29 Pages 2018
Subchronic toxicity study in rats evaluating genetically modified DAS-81419-2 soybean Fulltext Access 29 Pages 2018
Acrylamide applied during pregnancy causes the neurotoxic effect by lowering BDNF levels in the fetal brain Fulltext Access 29 Pages 2018
Association of exposure to manganese and iron with striatal and thalamic GABA and other neurometabolites - Neuroimaging results from the WELDOX II study Fulltext Access 29 Pages 2018
Gap junctional intercellular communication and endoplasmic reticulum stress regulate chronic cadmium exposure induced apoptosis in HK-2 cells Fulltext Access 29 Pages 2018
A biodynamic understanding of dietborne and waterborne Ag uptake from Ag NPs in the sediment-dwelling oligochaete, Tubifex tubifex Fulltext Access 29 Pages 2018
Exporisq-HAP database: 20 years of monitoring French occupational exposure to polycyclic aromatic hydrocarbon mixtures and identification of exposure determinants Fulltext Access 29 Pages 2018
Criticism of EFSA's scientific opinion on combinatorial effects of 'stacked' GM plants Fulltext Access 29 Pages 2018
In vitro toxicity evaluation of estragole-containing preparations derived from Foeniculum vulgare Mill. (fennel) on HepG2 cells Fulltext Access 29 Pages 2018
Aronia melanocarpa fruit juice ameliorates the symptoms of inflammatory bowel disease in TNBS-induced colitis in rats Fulltext Access 29 Pages 2018
Proteomic effects of repeated-dose oral exposure to 2-monochloropropanediol and its dipalmitate in rat testes Fulltext Access 29 Pages 2018
Sub-acute intravenous exposure to Fe2O3 nanoparticles does not alter cognitive performances and catecholamine levels, but slightly disrupts plasma iron level and brain iron content in rats Fulltext Access 29 Pages 2018
Organophosphate triesters and selected metabolites enhance binding of thyroxine to human transthyretin in vitro Fulltext Access 29 Pages 2018
Dose-dependent cytotoxicity of bismuth nanoparticles produced by LASiS in a reference mammalian cell line BALB/c 3T3 Fulltext Access 29 Pages 2018
Tribromophenol affects the metabolism, proliferation, migration and multidrug resistance transporters activity of murine melanoma cells B16F1 Fulltext Access 29 Pages 2018
Comparison of different cytotoxicity assays for in vitro evaluation of mesoporous silica nanoparticles Fulltext Access 29 Pages 2018
Monte Carlo based modelling approach for designing and predicting cytotoxicity of 2-phenylindole derivatives against breast cancer cell line MCF7 Fulltext Access 29 Pages 2018
Immunomodulation and cancer: Using mechanistic paradigms to inform risk assessment Fulltext Access 29 Pages 2018
RIFM fragrance ingredient safety assessment, (Z)-Octadec-9-enol, CAS Registry Number 143-28-2 Fulltext Access 29 Pages 2018
Evaluation of the inhibition effects of apatinib on human and rat cytochrome P450 Fulltext Access 29 Pages 2018
Uranium exposure of human dopaminergic cells results in low cytotoxicity, accumulation within sub-cytoplasmic regions, and down regulation of MAO-B Fulltext Access 29 Pages 2018
Ondansetron and teratogenicity in rats: Evidence for a mechanism mediated via embryonic hERG blockade Fulltext Access 29 Pages 2018
Baicalein represses TGF-β1-induced fibroblast differentiation through the inhibition of miR-21 Fulltext Access 29 Pages 2018
Effect of endocrine disruptors on the ratio of X and Y chromosome-bearing live spermatozoa Fulltext Access 29 Pages 2018
Tree nut allergy and anxiety related factors modulate food consumption behaviour in peanut-allergic patients: Results of the MIRABEL survey Fulltext Access 29 Pages 2018
Cytogenetic and genotoxic effects of Rosmaniric Acid on Allium cepa L. root meristem cells Fulltext Access 29 Pages 2018
Nrf1 is paved as a new strategic avenue to prevent and treat cancer, neurodegenerative and other diseases Fulltext Access 29 Pages 2018
ROS-independent toxicity of Fe3O4 nanoparticles to yeast cells: Involvement of mitochondrial dysfunction Fulltext Access 29 Pages 2018
Interaction of DNA with water soluble complex of Nickle and formation of DNA cross-links Fulltext Access 29 Pages 2018
A 14-day repeated-dose oral toxicological evaluation of an isothiocyanate-enriched hydro-alcoholic extract from Moringa oleifera Lam. seeds in rats Fulltext Access 29 Pages 2018
Di (2-ethylhexyl) phthalate (DEHP)-induced hepatotoxicity in quails (Coturnix japonica) via triggering nuclear xenobiotic receptors and modulating cytochrome P450 systems Fulltext Access 29 Pages 2018
Thiopurine-induced toxicity is associated with dysfunction variant of the human molybdenum cofactor sulfurase gene (xanthinuria type II) Fulltext Access 29 Pages 2018
Amelioration effect of Egyptian sweet orange hesperidin on Ehrlich ascites carcinoma (EAC) bearing mice Fulltext Access 29 Pages 2018
Residue analysis and dietary exposure risk assessment of tebufenozide in stem lettuce (Lactuca sativa L. var. angustana Irish) Fulltext Access 29 Pages 2018
Anti-proliferative activity-guided isolation of clerodermic acid from Salvia nemorosa L.: Geno/cytotoxicity and hypoxia-mediated mechanism of action Fulltext Access 29 Pages 2018
Zhiheshouwu ethanol extract induces intrinsic apoptosis and reduces unsaturated fatty acids via SREBP1 pathway in hepatocellular carcinoma cells Fulltext Access 29 Pages 2018
Antitrypanosomal, antileishmanial and cytotoxic activities of Brazilian red propolis and plant resin of Dalbergia ecastaphyllum (L) Taub Fulltext Access 29 Pages 2018
Effects of isopentyl ferulate on oxidative stress biomarkers and a possible GABAergic anxiolytic-like trait in Swiss mice Fulltext Access 29 Pages 2018
Multi-elemental composition and antioxidant properties of strawberry tree (Arbutus unedo L.) honey from the coastal region of Croatia: Risk-benefit analysis Fulltext Access 29 Pages 2018
Platycodon grandiflorum-derived saponin enhances exercise function, skeletal muscle protein synthesis, and mitochondrial function Fulltext Access 29 Pages 2018
Safety profile of AZT derivatives: Organoselenium moieties confer different cytotoxic responses in fresh human erythrocytes during in vitro exposures Fulltext Access 29 Pages 2018
Honey protects against wings posture error and molecular changes related to mitochondrial pathways induced by hypoxia/reoxygenation in adult Drosophila melanogaster Fulltext Access 30 Pages 2018
Patulin induced ROS-dependent autophagic cell death in Human Hepatoma G2 cells Fulltext Access 30 Pages 2018
Ovatodiolide suppresses yes-associated protein 1-modulated cancer stem cell phenotypes in highly malignant hepatocellular carcinoma and sensitizes cancer cells to chemotherapy in vitro Fulltext Access 30 Pages 2018
Removal of azo dye using Fenton and Fenton-like processes: Evaluation of process factors by Box-Behnken design and ecotoxicity tests Fulltext Access 30 Pages 2018
Pre-validation of an in vitro skin irritation test for medical devices using the reconstructed human tissue model EpiDerm⢠Fulltext Access 30 Pages 2018
Acrolein-induced autophagy-dependent apoptosis via activation of the lysosomal-mitochondrial pathway in EAhy926 cells Fulltext Access 30 Pages 2018
HPLC-DAD fingerprinting analysis, antioxidant activities of Tithonia diversifolia (Hemsl.) A. Gray leaves and its inhibition of key enzymes linked to Alzheimer's disease Fulltext Access 30 Pages 2018
NiO nanoparticles induce cytotoxicity mediated through ROS generation and impairing the antioxidant defense in the human lung epithelial cells (A549): Preventive effect of Pistacia lentiscus essential oil Fulltext Access 30 Pages 2018
Effects of Î9-tetrahydrocannabinol on irinotecan-induced clinical effects in rats Fulltext Access 30 Pages 2018
Dauricine upregulates the chemosensitivity of hepatocellular carcinoma cells: Role of repressing glycolysis via miR-199a:HK2/PKM2 modulation Fulltext Access 30 Pages 2018
Analysis of 3â²,5â²-dichloro-2,3,4-trihydroxy-2-methylbutylanilide (DTMBA) as a new potential biomarker of exposure to vinclozolin in urine Fulltext Access 30 Pages 2018
1800âMHz radiofrequency fields inhibits testosterone production via CaMKI /RORα pathway Fulltext Access 30 Pages 2018
Monosodium glutamate induced nociception and oxidative stress dependent on time of administration, age of rats and susceptibility of spinal cord and brain regions Fulltext Access 30 Pages 2018
Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells Fulltext Access 30 Pages 2018
Oxidative stress caused by TiO2 nanoparticles under UV irradiation is due to UV irradiation not through nanoparticles Fulltext Access 30 Pages 2018
Glycyrrhizin attenuates histamine-mediated MUC5AC upregulation, inflammatory cytokine production, and aquaporin 5 downregulation through suppressing the NF-κB pathway in human nasal epithelial cells Fulltext Access 30 Pages 2018
Triptolide enhances chemotherapeutic efficacy of antitumor drugs in non-small-cell lung cancer cells by inhibiting Nrf2-ARE activity Fulltext Access 30 Pages 2018
Schisandrin B exhibits potent anticancer activity in triple negative breast cancer by inhibiting STAT3 Fulltext Access 30 Pages 2018
Expression of cytochrome P450 epoxygenases and soluble epoxide hydrolase is regulated by hypolipidemic drugs in dose-dependent manner Fulltext Access 30 Pages 2018
Cunaniol-elicited seizures: Behavior characterization and electroencephalographic analyses Fulltext Access 30 Pages 2018
ERK1/2-mediated autophagy is essential for cell survival under Ochratoxin A exposure in IPEC-J2 cells Fulltext Access 30 Pages 2018
Xanthohumol inhibits cell proliferation and induces apoptosis in human thyroid cells Fulltext Access 30 Pages 2018
C. elegans Development and Activity Test detects mammalian developmental neurotoxins Fulltext Access 30 Pages 2018
Manganese exposure: Linking down-regulation of miRNA-7 and miRNA-433 with α-synuclein overexpression and risk of idiopathic Parkinson's disease Fulltext Access 30 Pages 2018
S-allyl-glutathione, a synthetic analogue of glutathione protected liver against carbon tetrachloride toxicity: Focus towards anti-oxidative efficiency Fulltext Access 30 Pages 2018
Case studies on genetically modified organisms (GMOs): Potential risk scenarios and associated health indicators Fulltext Access 30 Pages 2018
Highly sensitive SERS immunosensor for the detection of amantadine in chicken based on flower-like gold nanoparticles and magnetic bead separation Fulltext Access 30 Pages 2018
Oral exposure to silver nanoparticles increases oxidative stress markers in the liver of male rats and deregulates the insulin signalling pathway and p53 and cleaved caspase 3 protein expression Fulltext Access 30 Pages 2018
Chemical characterization, antioxidant, genotoxic and in vitro cytotoxic activity assessment of Juniperus communis var. saxatilis Fulltext Access 30 Pages 2018
Evaluation of the antioxidant and gastroprotective activity and HPLC analysis of the hydroalcoholic extract of Tocoyena formosa leaves (Cham. & Schlecht) K. Schum Fulltext Access 30 Pages 2018
Evaluation of antioxidant activities of ethanol extract from Ligusticum subjected to in-vitro gastrointestinal digestion Fulltext Access 30 Pages 2018
Development and validation of a rapid RP-HPLC-DAD analysis method for the quantification of pilocarpine in Pilocarpus microphyllus (Rutaceae) Fulltext Access 30 Pages 2018
Neuroprotective effects of cordycepin inhibit Aβ-induced apoptosis in hippocampal neurons Fulltext Access 30 Pages 2018
Isoliquiritigenin attenuates glutamate-induced mitochondrial fission via calcineurin-mediated Drp1 dephosphorylation in HT22 hippocampal neuron cells Fulltext Access 30 Pages 2018
Agathisflavone, a flavonoid derived from Poincianella pyramidalis (Tul.), enhances neuronal population and protects against glutamate excitotoxicity Fulltext Access 30 Pages 2018
Hsp90 Co-chaperone p23 contributes to dopaminergic mitochondrial stress via stabilization of PHD2: Implications for Parkinson's disease Fulltext Access 30 Pages 2018
Brain derived neurotrophic factor (BDNF), its tyrosine kinase receptor B (TrkB) and nicotine Fulltext Access 30 Pages 2018
Environmental neurotoxicant manganese regulates exosome-mediated extracellular miRNAs in cell culture model of Parkinson's disease: Relevance to α-synuclein misfolding in metal neurotoxicity Fulltext Access 30 Pages 2018
Resveratrol attenuates oxidative damage through activating mitophagy in an in vitro model of Alzheimer's disease Fulltext Access 30 Pages 2018
The food safety of DP-356Ã43 soybeans on SD rats reflected by physiological variables and fecal microbiota during a 90-day feeding study Fulltext Access 30 Pages 2018
Effects of low concentrations of ibuprofen on freshwater fish Rhamdia quelen Fulltext Access 30 Pages 2018
No subchronic toxicity of multiple herbicide-resistant soybean FG72 in Sprague-Dawley rats by 90-days feeding study Fulltext Access 30 Pages 2018
Melatonin attenuates Î9-tetrahydrocannabinol-induced reduction in rat sperm motility and kinematics in-vitro Fulltext Access 30 Pages 2018
Cynatratoside-C from Cynanchum atratum displays anti-inflammatory effect via suppressing TLR4 mediated NF-κB and MAPK signaling pathways in LPS-induced mastitis in mice Fulltext Access 30 Pages 2018
Effects of Î(9)-tetrahydrocannabinol (THC) on human amniotic epithelial cell proliferation and migration. Fulltext Access 30 Pages 2018
Coagonist of GLP-1 and glucagon decreases liver inflammation and atherosclerosis in dyslipidemic condition Fulltext Access 30 Pages 2018
Activation of p62-keap1-Nrf2 antioxidant pathway in the early stage of acetaminophen-induced acute liver injury in mice Fulltext Access 30 Pages 2018
Mass spectrometric analysis of sulfur mustard-induced biomolecular adducts: Are DNA adducts suitable biomarkers of exposure? Fulltext Access 30 Pages 2018
Leaves and stem bark from Allophylus africanus P. Beauv.: An approach to anti-inflammatory properties and characterization of their flavonoid profile Fulltext Access 30 Pages 2018
The size of zinc oxide nanoparticles controls its toxicity through impairing autophagic flux in A549 lung epithelial cells Fulltext Access 30 Pages 2018
ULK1-regulated autophagy: A mechanism in cellular protection for ALDH2 against hyperglycemia Fulltext Access 30 Pages 2018