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Daneshyari Toxicology Journas Latest Articles

Toxicology Research Articles

Metabonomics reveals that triclocarban affects liver metabolism by affecting glucose metabolism, β-oxidation of fatty acids, and the TCA cycle in male mice
Fulltext Access 27 Pages 2018
The BH3 mimetic compound BH3I-1 impairs mitochondrial dynamics and promotes stress response in addition to its pro-apoptotic key function
Fulltext Access 27 Pages 2018
Heme Oxygenase-1 protects astroglia against manganese-induced oxidative injury by regulating mitochondrial quality control
Fulltext Access 27 Pages 2018
Assessment of N-acetylcysteine as a therapy for phosgene-induced acute lung injury
Fulltext Access 27 Pages 2018
Metabolomic analysis uncovered an association of serum phospholipid levels with estrogen-induced mammary tumors in female ACI/Seg rats
Fulltext Access 27 Pages 2018
Triptolide suppresses paraquat induced idiopathic pulmonary fibrosis by inhibiting TGFB1-dependent epithelial mesenchymal transition
Fulltext Access 27 Pages 2018
Effect of UGT2B7*2 and CYP2C8*4 polymorphisms on diclofenac metabolism
Fulltext Access 27 Pages 2018
Kinetic time courses of lambda-cyhalothrin metabolites after dermal application of Matador EC 120 in volunteers
Fulltext Access 27 Pages 2018
Mitochondrial bioenergetics and locomotor activity are altered in zebrafish (Danio rerio) after exposure to the bipyridylium herbicide diquat
Fulltext Access 27 Pages 2018
Impact of fasting followed by short-term exposure to interleukin-6 on cytochrome P450 mRNA in mice
Fulltext Access 27 Pages 2018
Transcriptional inhibition of TCDD-mediated induction of cytochrome P450 1A1 and alteration of protein expression in a zebrafish hepatic cell line following the administration of TCDD and Cd2+
Fulltext Access 27 Pages 2018
UVA and UVB formulation phototoxicity in a three-dimensional human skin model: Photodegradation effect
Fulltext Access 27 Pages 2018
Role of the equine CYP3A94, CYP3A95 and CYP3A97 in ketamine metabolism in presence of medetomidine, diazepam and methadone studied by enantioselective capillary electrophoresis
Fulltext Access 27 Pages 2018
MicroRNA-191, regulated by HIF-2α, is involved in EMT and acquisition of a stem cell-like phenotype in arsenite-transformed human liver epithelial cells
Fulltext Access 27 Pages 2018
Immunofluorescence/fluorescence assessment of brain-derived neurotrophic factor, c-Fos activation, and apoptosis in the brain of zebrafish (Danio rerio) larvae exposed to glufosinate
Fulltext Access 27 Pages 2018
Latent consequences of early-life lead (Pb) exposure and the future: Addressing the Pb crisis
Fulltext Access 27 Pages 2018
Children's contrast sensitivity function in relation to organophosphate insecticide prenatal exposure in the mother-child PELAGIE cohort
Fulltext Access 27 Pages 2018
Neuroprotective action of 4-Hydroxyisophthalic acid against paraquat-induced motor impairment involves amelioration of mitochondrial damage and neurodegeneration in Drosophila
Fulltext Access 27 Pages 2018
Developmental exposure to low concentrations of two brominated flame retardants, BDE-47 and BDE-99, causes life-long behavioral alterations in zebrafish
Fulltext Access 27 Pages 2018
The STIM1 inhibitor ML9 disrupts basal autophagy in cardiomyocytes by decreasing lysosome content
Fulltext Access 27 Pages 2018
Hypoxia regulates the level of glutamic acid decarboxylase enzymes and interrupts inhibitory synapse stability in primary cultured neurons
Fulltext Access 28 Pages 2018
Effects of bisphenol A and its analogs on reproductive health: A mini review
Fulltext Access 28 Pages 2018
Hydroxyurea embryotoxicity is enhanced in P53-deficient mice
Fulltext Access 28 Pages 2018
Safety assessment of ethanolic extract of Olea europaea L. leaves after acute and subacute administration to Wistar rats
Fulltext Access 28 Pages 2018
Multigenerational effects of maternal cigarette smoke exposure during pregnancy on sperm counts of F1 and F2 male offspring
Fulltext Access 28 Pages 2018
Ferroptosis is newly characterized form of neuronal cell death in response to arsenite exposure
Fulltext Access 28 Pages 2018
Acute and repeated dose 28-day oral toxicity of poly(3-hydroxybutyrate-co-4-hydroxybutyrate) nanoparticles in Sprague-Dawley rats
Fulltext Access 28 Pages 2018
Inhibition of protein tyrosine phosphatase 1B by flavonoids: A structure - activity relationship study
Fulltext Access 28 Pages 2018
Microcystis bloom containing microcystin-LR induces type 2 diabetes mellitus
Fulltext Access 28 Pages 2018
Oxidative stress, caspase-3 activation and cleavage of ROCK-1 play an essential role in MeHg-induced cell death in primary astroglial cells
Fulltext Access 28 Pages 2018
Nobiletin bioactivation in MDA-MB-468 breast cancer cells by cytochrome P450 CYP1 enzymes
Fulltext Access 28 Pages 2018
Differential responses of lineages-committed hematopoietic progenitors and altered expression of self-renewal and differentiation-related genes in 1,4-benzoquinone (1,4-BQ) exposure
Fulltext Access 28 Pages 2018
Evaluating opportunities for advancing the use of alternative methods in risk assessment through the development of fit-for-purpose in vitro assays
Fulltext Access 28 Pages 2018
9-O-benzoyl-substituted berberine exerts a triglyceride-lowering effect through AMPK signaling pathway in human hepatoma HepG2 cells
Fulltext Access 28 Pages 2018
FDA regulatory approach to steviol glycosides
Fulltext Access 28 Pages 2018
Protective effects of apigenin against 3-MCPD-induced renal injury in rat
Fulltext Access 28 Pages 2018
Development of a human physiologically based pharmacokinetic (PBPK) model for phthalate (DEHP) and its metabolites: A bottom up modeling approach
Fulltext Access 28 Pages 2018
Captan-induced increase in the concentrations of intracellular Ca2+ and Zn2+ and its correlation with oxidative stress in rat thymic lymphocytes
Fulltext Access 28 Pages 2018
CSF sodium at toxic levels precedes delirium in hip fracture patients
Fulltext Access 28 Pages 2018
Propranolol inhibits proliferation and invasion of hemangioma-derived endothelial cells by suppressing the DLL4/Notch1/Akt pathway
Fulltext Access 28 Pages 2018
Steroidogenic disruptive effects of the serotonin-noradrenaline reuptake inhibitors duloxetine, venlafaxine and tramadol in the H295R cell assay and in a recombinant CYP17 assay
Fulltext Access 28 Pages 2018
Degradation of pesticides with RSDL® (reactive skin decontamination lotion kit) lotion: LC-MS investigation
Fulltext Access 28 Pages 2018
TGFβ1-mediated suppression of cytochrome P450(CYP) induction responses in rat hepatocyte-fibroblast co-cultures
Fulltext Access 28 Pages 2018
Silicon dioxide nanoparticles induce COX-2 expression through activation of STAT3 signaling pathway in HaCaT cells
Fulltext Access 28 Pages 2018
Phenotypic markers of oral keratinocytes seeded on two distinct 3D oral mucosa models
Fulltext Access 28 Pages 2018
Anticancer activity of flavonoids isolated from Achyrocline satureioides in gliomas cell lines
Fulltext Access 28 Pages 2018
Low-functional programming of the CREB/BDNF/TrkB pathway mediates cognitive impairment in male offspring after prenatal dexamethasone exposure
Fulltext Access 28 Pages 2018
PGAM5 regulates PINK1/Parkin-mediated mitophagy via DRP1 in CCCP-induced mitochondrial dysfunction
Fulltext Access 28 Pages 2018
NLRP3 inflammasome activation in the thymus of MPTP-induced Parkinsonian mouse model
Fulltext Access 28 Pages 2018
Development of an ELISA assay to determine neutralising capacity of horse serum following immunisation with Daboia siamensis venom in Myanmar
Fulltext Access 28 Pages 2018
StaySafe: A self-administered android tablet application for helping individuals on probation make better decisions pertaining to health risk behaviors
Fulltext Access 28 Pages 2018
Tatanan A from the Acorus calamus L. root inhibited dengue virus proliferation and infections
Fulltext Access 28 Pages 2018
Bavachalcone from Cullen corylifolium induces apoptosis and autophagy in HepG2 cells
Fulltext Access 28 Pages 2018
Chemical analysis of aqueous extracts of Origanum majorana and Foeniculum vulgare and their efficacy on Blastocystis spp. cysts
Fulltext Access 28 Pages 2018
Determination of quality markers of Xuezhiling tablet for hyperlipidemia treatment
Fulltext Access 28 Pages 2018
Exposure to diisodecyl phthalate exacerbated Th2 and Th17-mediated asthma through aggravating oxidative stress and the activation of p38 MAPK
Fulltext Access 28 Pages 2018
Extending knowledge of the clinical picture of Balkan adder (Vipera berus bosniensis) envenoming: The first photographically-documented neurotoxic case from South-Western Hungary
Fulltext Access 28 Pages 2018
Role of l-amino acid oxidase isolated from Calloselasma rhodostoma venom on neutrophil NADPH oxidase complex activation
Fulltext Access 28 Pages 2018
Coptisine-induced apoptosis in human colon cancer cells (HCT-116) is mediated by PI3K/Akt and mitochondrial-associated apoptotic pathway
Fulltext Access 28 Pages 2018
Identification of a unique insertion in plant organellar DNA polymerases responsible for 5′-dRP lyase and strand-displacement activities: Implications for Base Excision Repair
Fulltext Access 28 Pages 2018
Expression of zinc transporters ZIP4, ZIP14 and ZnT9 in hepatic carcinogenesis-An immunohistochemical study
Fulltext Access 28 Pages 2018
Quantification of spheno-occipital synchondrosis fusion in a contemporary Malaysian population
Fulltext Access 28 Pages 2018
Post-feeding activity of Lucilia sericata (Diptera: Calliphoridae) on common domestic indoor surfaces and its effect on development
Fulltext Access 28 Pages 2018
GPR and ERT detection and characterization of a mass burial, Spanish Civil War, Northern Spain
Fulltext Access 28 Pages 2018
Estimating the age of Lucilia illustris during the intrapuparial period using two approaches: Morphological changes and differential gene expression
Fulltext Access 28 Pages 2018
Investigation of some of the factors influencing fingermark detection
Fulltext Access 28 Pages 2018
Course-, dose-, and stage-dependent toxic effects of prenatal dexamethasone exposure on long bone development in fetal mice
Fulltext Access 28 Pages 2018
RIFM fragrance ingredient safety assessment, 2-methylundecanal dimethyl acetal, CAS Registry Number 68141-17-3
Fulltext Access 28 Pages 2018
Micronucleus induction and cell cycle alterations produced by deoxynivalenol and its acetylated derivatives in individual and combined exposure on HepG2 cells
Fulltext Access 28 Pages 2018
A comparative study of the disinfection efficacy of H2O2/ferrate and UV/H2O2/ferrate processes on inactivation of Bacillus subtilis spores by response surface methodology for modeling and optimization
Fulltext Access 28 Pages 2018
Effects of different Ca2+ level on fluoride-induced apoptosis pathway of endoplasmic reticulum in the rabbit osteoblast in vitro
Fulltext Access 28 Pages 2018
Achillea millefolium L. hydroethanolic extract inhibits growth of human tumor cell lines by interfering with cell cycle and inducing apoptosis
Fulltext Access 28 Pages 2018
Genipin inhibits the invasion and migration of colon cancer cells by the suppression of HIF-1α accumulation and VEGF expression
Fulltext Access 28 Pages 2018
Protection of cyanidin-3-O-glucoside against acrylamide- and glycidamide-induced reproductive toxicity in leydig cells
Fulltext Access 28 Pages 2018
Acute toxicity, uptake, and elimination of zinc oxide nanoparticles (ZnO NPs) using saltwater microcrustacean, Artemia franciscana
Fulltext Access 28 Pages 2018
Ecotoxicological effect of fipronil and its metabolites on Folsomia candida in tropical soils
Fulltext Access 28 Pages 2018
The use of liver slices from the Cape vulture (Gyps coprotheres) to better understand the role of liver toxicity of non-steroidal anti-inflammatory drugs (NSAIDs) in vultures
Fulltext Access 28 Pages 2018
BET-inhibition by JQ1 alleviates streptozotocin-induced diabetic cardiomyopathy
Fulltext Access 28 Pages 2018
Toxicological assessment of PEGylated single-walled carbon nanotubes in early developing zebrafish
Fulltext Access 28 Pages 2018
Teroxirone motivates apoptotic death in tumorspheres of human lung cancer cells
Fulltext Access 28 Pages 2018
Regulation and role of nuclear factor-E2-related factor 2 (Nrf2) in multidrug resistance of hepatocellular carcinoma
Fulltext Access 28 Pages 2018
The in vitro radiosensitizer potential of resveratrol on MCF-7 breast cancer cells
Fulltext Access 28 Pages 2018
An integrated strategy for rapid discovery and identification of quality markers in Guanxin Kangtai preparation using UHPLC-TOF/MS and multivariate statistical analysis
Fulltext Access 29 Pages 2018
The 2016 ENFSI Fingerprint Working Group testing programme
Fulltext Access 29 Pages 2018
1,5-Anhydro-d-glucitol in vitreous humor and cerebrospinal fluid - A helpful tool for identification of diabetes and diabetic coma post mortem
Fulltext Access 29 Pages 2018
Pharmacotherapy for amphetamine dependence: A systematic review
Fulltext Access 29 Pages 2018
Molecular modeling and in vitro approaches towards cholinesterase inhibitory effect of some natural xanthohumol, naringenin, and acyl phloroglucinol derivatives
Fulltext Access 29 Pages 2018
Novel RAS inhibitor 25-O-methylalisol F attenuates epithelial-to-mesenchymal transition and tubulo-interstitial fibrosis by selectively inhibiting TGF-β-mediated Smad3 phosphorylation
Fulltext Access 29 Pages 2018
Borderline personality disorder symptoms in treatment-naïve actively drinking alcoholics
Fulltext Access 29 Pages 2018
Difference in sensitivities of blood HDL cholesterol and LDL cholesterol levels to alcohol in middle-aged Japanese men
Fulltext Access 29 Pages 2018
Lipidome of plasma lipoproteins and liver is zinc- modulated in High fat diet treated mice
Fulltext Access 29 Pages 2018
Workers of São Paulo city, Brazil, exposed to air pollution: Assessment of genotoxicity
Fulltext Access 29 Pages 2018
Preclinical evaluation of the neutralizing ability of a monospecific antivenom for the treatment of envenomings by Bothrops lanceolatus in Martinique
Fulltext Access 29 Pages 2018
Rational design of botulinum neurotoxin A1 mutants with improved oxidative stability
Fulltext Access 29 Pages 2018
Conservation analysis and decomposition of residue correlation networks in the phospholipase A2 superfamily (PLA2s): Insights into the structure-function relationships of snake venom toxins
Fulltext Access 29 Pages 2018
Effects of combined treatment with ochratoxin A and citrinin on oxidative damage in kidneys and liver of rats
Fulltext Access 29 Pages 2018
Adsorptive removal of microcystin-LR from surface and wastewater using tyre-based powdered activated carbon: Kinetics and isotherms
Fulltext Access 29 Pages 2018
Inhibitory effect of Ligustrum vulgare leaf extract on the development of neuropathic pain in a streptozotocin-induced rat model of diabetes
Fulltext Access 29 Pages 2018
Simulation of mouse and rat spermatogenesis to inform genotoxicity testing using OECD test guideline 488
Fulltext Access 29 Pages 2018
Tracing the evolution of venom phospholipases A2 in Gloydius strauchii and related pitvipers: A tale of two acidic isozymes
Fulltext Access 29 Pages 2018
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