Antiproliferative effects of formononetin on human colorectal cancer via suppressing cell growth in vitro and in vivo

- Formononetin (FT) inhibits RKO cell proliferation.
- FT inactivates ERK pathway associated with cell proliferation.
- FT induces apoptosis in human colorectal cancer cells.
- FT inhibits tumor growth in vivo via blocking TNF-α/NF-κB pathway.
- FT may be a new therapeutic strategy for treating colorectal cancer.