Development, characterization and antimalarial efficacy of dihydroartemisinin loaded solid lipid nanoparticles

Dihydroartemisinin (DHA) was packaged into solid lipid nanoparticles achieving desirable particle characteristics for nanomedicine drug delivery. The spherical DHA-SLNs were examined for antimalarial efficacy using both in vitro culture method and in vivo mice model. Results indicated significant enhancement of efficacy when compared to free DHA.78