کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1201767 1493656 2012 17 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Recent development of cyclodextrin chiral stationary phases and their applications in chromatography
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Recent development of cyclodextrin chiral stationary phases and their applications in chromatography
چکیده انگلیسی

The current article reviews the development and applications of novel cyclodextrin chiral stationary phases (CD-CSPs) in liquid chromatography (LC), capillary electrochromatography (CEC), gas chromatography (GC) and supercritical fluid chromatography (SFC) over the period of January 2007 to March 2012. The synthetic routes of CD-CSPs, as well as the presence of selective functional groups in effecting inclusion complexation and molecular interactions have been found to exert profound influence in the enantioseparation process. In this article, various synthetic and functional groups immobilization strategies of novel CD-CSPs, and their applications in chiral resolution using different chromatography techniques are discussed. After introducing the topic in Section 1, Section 2 describes novel CD-CSPs in LC applications, where the CSPs are classified according to its coating approaches (physical and chemical manners) for ease of readership. Section 3 discusses recent development of CD-CSPs in open tubular CEC (OT-CEC), packed-bed CEC (P-CEC), pseudostationary phase CEC (PSP-CEC) and monolithic CEC. The last part illustrates novel CD-CSPs in gas chromatography (GC) and supercritical fluid chromatography (SFC).


► Review of novel cyclodextrin chiral stationary phases (CD-CSPs) in chromatography.
► Review period from January 2007 to March 2012.
► The synthetic strategy of CD-CSPs was found to affect enantioseparation.
► CD functional groups affect inclusion complexation and molecular interactions.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Chromatography A - Volume 1269, 21 December 2012, Pages 52–68
نویسندگان
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