BF3·nano SiO2 as a catalytic system for one-pot green synthesis of pyrophthalone derivatives under microwave conditions : 1st Nano Update

The expeditious and solvent-free approach that involves the exposure of neat reactants to microwave (MW) irradiation in conjunction with the use of supported catalysts was described. A simple one-pot and green reaction of methylpyridine derivatives and phthalic anhydride derivatives on the surface of a nano silica gel impregnated with BF3 as solid supported catalysts under microwave irradiation without any solvent according to green chemistry was developed. The salient features of these high yield protocols are the enhanced reaction rates, greater selectivity and the experimental ease of manipulation.