کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
2076461 | 1079446 | 2009 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Modeling of glycolytic wave propagation in an open spatial reactor with inhomogeneous substrate influx
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
ریاضیات
مدلسازی و شبیه سازی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The spatio-temporal dynamics of traveling waves in glycolysis as it occurs in yeast extract have been studied, both theoretically and experimentally. We describe this phenomenon with the distributed Selkov model that accounts for the reactions of phosphofructokinase, which is a key enzyme of the glycolytic reaction cascade. To describe the experimentally observed phase waves in an open spatial reactor we introduce a non-homogeneous flux of substrate in the model. The experimental observation that waves can change their direction of propagation during the experiment is considered in the model. The mechanism for such a change in wave direction is discussed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosystems - Volume 97, Issue 2, August 2009, Pages 127-133
Journal: Biosystems - Volume 97, Issue 2, August 2009, Pages 127-133
نویسندگان
A.I. Lavrova, S. Bagyan, T. Mair, M.J.B. Hauser, L. Schimansky-Geier,