کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
2076514 1079450 2009 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Optimal treatment of an SIR epidemic model with time delay
موضوعات مرتبط
مهندسی و علوم پایه ریاضیات مدل‌سازی و شبیه سازی
پیش نمایش صفحه اول مقاله
Optimal treatment of an SIR epidemic model with time delay
چکیده انگلیسی

In this paper the optimal control strategies of an SIR (susceptible–infected–recovered) epidemic model with time delay are introduced. In order to do this, we consider an optimally controlled SIR epidemic model with time delay where a control means treatment for infectious hosts. We use optimal control approach to minimize the probability that the infected individuals spread and to maximize the total number of susceptible and recovered individuals. We first derive the basic reproduction number and investigate the dynamical behavior of the controlled SIR epidemic model. We also show the existence of an optimal control for the control system and present numerical simulations on real data regarding the course of Ebola virus in Congo. Our results indicate that a small contact rate(probability of infection) is suitable for eradication of the disease (Ebola virus) and this is one way of optimal treatment strategies for infectious hosts.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biosystems - Volume 98, Issue 1, October 2009, Pages 43–50
نویسندگان
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