|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|4914576||1362626||2018||5 صفحه PDF||ندارد||دانلود رایگان|
â¢SC-CO2 extraction coupled with fractional separation has been used.â¢250Â bar, 40Â Â°C were the optimized extraction conditions.â¢The extraction process was faster when R. graveolens particle size was smaller.â¢Fractional separation allowed the selective elimination of cuticular waxes.
Supercritical CO2 (SC-CO2) extraction coupled with fractional separation of the extracts, has been used to concentrate the active principles of Ruta graveolens. Using 250Â bar, 40Â Â°C for the extraction process and cooling the first separator to â10Â Â°C, an efficient extraction and fractionation was obtained. Different particle sizes of the vegetable matter were tested (from 0.20 to 0.80Â mm); they indicated that the extraction process was faster when particle size was smaller; i.e., internal mass transfer controlled the process. Fractional separation allowed the selective elimination of cuticular waxes, that represented about 78% w/w of the total extract produced by SC-CO2 processing. The extract collected in the second separator was concentrated in active compounds up to 87% w/w. For comparison purposes, extraction was also performed using an organic solvent: the extract obtained using ethyl-acetate, contained low percentages of active compounds, mainly due to the co-extraction of large quantities of waxes.
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Journal: The Journal of Supercritical Fluids - Volume 131, January 2018, Pages 82-86